scholarly journals Ambulatory Management of Worsening Heart Failure: Current Strategies and Future Directions

2021 ◽  
Vol 15 (1) ◽  
pp. 49
Author(s):  
Alison L Wand ◽  
Stuart D Russell ◽  
Nisha A Gilotra ◽  
◽  
◽  
...  
Keyword(s):  
Heart Failure ◽  
Future Directions

Heart failure and atrial fibrillation: new concepts in pathophysiology, management, and future directions

2021 ◽  
Author(s):  
Grigorios Tsigkas ◽  
Anastasios Apostolos ◽  
Stefanos Despotopoulos ◽  
Georgios Vasilagkos ◽  
Eleftherios Kallergis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Future Directions ◽  
New Concepts

scholarly journals Family Caregiving for Individuals With Heart Failure: A Scientific Statement From the American Heart Association

Circulation ◽  
2020 ◽  
Vol 141 (22) ◽  
Author(s):  
Lisa Kitko ◽  
Colleen K. McIlvennan ◽  
Julie T. Bidwell ◽  
J. Nicholas Dionne-Odom ◽  
Shannon M. Dunlay ◽  
...  
Keyword(s):  
Heart Failure ◽  
Family Caregiving ◽  
Heart Association ◽  
Well Being ◽  
Clinical Settings ◽  
Financial Health ◽  
Future Directions ◽  
Scientific Statement ◽  
The Relationship ◽  
Health And Well Being

Many individuals living with heart failure (HF) rely on unpaid support from their partners, family members, friends, or neighbors as caregivers to help manage their chronic disease. Given the advancements in treatments and devices for patients with HF, caregiving responsibilities have expanded in recent decades to include more intensive care for increasingly precarious patients with HF—tasks that would previously have been undertaken by healthcare professionals in clinical settings. The specific tasks of caregivers of patients with HF vary widely based on the patient’s symptoms and comorbidities, the relationship between patient and caregiver, and the complexity of the treatment regimen. Effects of caregiving on the caregiver and patient range from physical and psychological to financial. Therefore, it is critically important to understand the needs of caregivers to support the increasingly complex medical care they provide to patients living with HF. This scientific statement synthesizes the evidence pertaining to caregiving of adult individuals with HF in order to (1) characterize the HF caregiving role and how it changes with illness trajectory; (2) describe the financial, health, and well-being implications of caregiving in HF; (3) evaluate HF caregiving interventions to support caregiver and patient outcomes; (4) summarize existing policies and resources that support HF caregivers; and (5) identify knowledge gaps and future directions for providers, investigators, health systems, and policymakers.

Heart failure with preserved ejection fraction: controversies, challenges and future directions

Heart ◽  
2018 ◽  
Vol 104 (5) ◽  
pp. 377-384 ◽  
Author(s):  
Rosita Zakeri ◽  
Martin R Cowie
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Management Strategies ◽  
Cyclic Guanosine Monophosphate ◽  
Guanosine Monophosphate ◽  
Protein Kinase G ◽  
Preserved Ejection Fraction ◽  
Future Directions ◽  
Novel Treatments ◽  
Inflammatory State

Heart failure with preserved ejection fraction (HFpEF) comprises almost half of the population burden of HF. Because HFpEF likely includes a range of cardiac and non-cardiac abnormalities, typically in elderly patients, obtaining an accurate diagnosis may be challenging, not least due to the existence of multiple HFpEF mimics and a newly identified subset of patients with HFpEF and normal plasma natriuretic peptide concentrations. The lack of effective treatment for these patients represents a major unmet clinical need. Heterogeneity within the patient population has triggered debate over the aetiology and pathophysiology of HFpEF, and the neutrality of randomised clinical trials suggests that we do not fully understand the syndrome(s). Dysregulated nitric oxide–cyclic guanosine monophosphate–protein kinase G signalling, driven by comorbidities and ageing, may be the fundamental abnormality in HFpEF, resulting in a systemic inflammatory state and microvascular endothelial dysfunction. Novel informatics platforms are also being used to classify HFpEF into subphenotypes, based on statistically clustered clinical and biological characteristics: whether such subclassification will lead to more targeted therapies remains to be seen. In this review, we summarise current concepts and controversies, and highlight the diagnostic and therapeutic challenges in clinical practice. Novel treatments and disease management strategies are discussed, and the large gaps in our knowledge identified.

scholarly journals Update on heart failure management and future directions

2019 ◽  
Vol 34 (1) ◽  
pp. 11-43 ◽  
Author(s):  
Hong-Mi Choi ◽  
Myung-Soo Park ◽  
Jong-Chan Youn
Keyword(s):  
Heart Failure ◽  
Heart Failure Management ◽  
Future Directions

Heart failure with preserved ejection fraction: future directions in medical treatment

2013 ◽  
Vol 11 (9) ◽  
pp. 1085-1087
Author(s):  
Dimitrios M Konstantinou ◽  
Yiannis S Chatzizisis ◽  
George D Giannoglou
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Medical Treatment ◽  
Preserved Ejection Fraction ◽  
Future Directions

scholarly journals Response to Letter Regarding Article, “Hydralazine and Isosorbide Dinitrate in Heart Failure: Historical Perspectives, Mechanisms, and Future Directions”

Circulation ◽  
2011 ◽  
Vol 124 (23) ◽  
Author(s):  
Robert T. Cole ◽  
Andreas P. Kalogeropoulos ◽  
Vasiliki V. Georgiopoulou ◽  
Arshed A. Quyyumi ◽  
Javed Butler ◽  
...  
Keyword(s):  
Heart Failure ◽  
Isosorbide Dinitrate ◽  
Future Directions ◽  
Historical Perspectives

scholarly journals Beta-blockers in heart failure: Future directions

1996 ◽  
Vol 17 (suppl B) ◽  
pp. 39-42 ◽  
Author(s):  
N. Sharpe
Keyword(s):  
Heart Failure ◽  
Beta Blockers ◽  
Future Directions

scholarly journals Letter by Makkar et al Regarding Article, “Cell Therapy for Heart Failure: A Comprehensive Overview of Experimental and Clinical Studies, Current Challenges, and Future Directions”

2014 ◽  
Vol 115 (11) ◽  
Author(s):  
Raj R. Makkar ◽  
Rachel R. Smith ◽  
Lawrence S.C. Czer ◽  
Stuart D. Russell ◽  
Gary Gerstenblith ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cell Therapy ◽  
Clinical Studies ◽  
Comprehensive Overview ◽  
Future Directions
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