Effect of Anterolateral Thigh Perforator Flap Repair on the Appearance, Language and Masticatory Function of Oral Cancer Patients after Radical Surgery

2021 ◽  
Vol 7 (5) ◽  
pp. 4277-4285
Author(s):  
Fengchun Hou ◽  
Di Wang ◽  
Tao Jiang
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Myocutaneous Flap ◽  
Perforator Flap ◽  
Pectoralis Major ◽  
Pectoralis Major Myocutaneous Flap ◽  
Control Group ◽  
Study Group ◽  
Masticatory Function ◽  
Oral Cancer Patients

Purpose: The purpose was to explore the application effect of anterolateral thigh perforator flap (ALTP) and pectoralis major myocutaneous flap on repairing the tissuedefects after oral cancer surgery. Methods: 100 oral cancer patients treated in our hospital from January 2018 to December 2020 were selected as the research objects. After both groups of patients received extended resection of tumors, neck lymph node dissection and other routine treatment, the control group was repaired by pectoralis major myocutaneous flap while the study group was repaired by ALTP to compare the flap survival rate, language, masticatory function and other related indicators between the two groups. Results: The flap harvesting time and defect repair time in the control group were shorter than those in the study group (P<0.05); The language, masticatory function and swallowing function in both groups after treatment were significantly better than those before treatment (P<0.05); The total incidence of complications in the study group was significantly lower than that in the control group (P<0.05); After treatment, the quality of life scores in both groups were significantly higher than those before treatment (P<0.05). Conclusion: Both ALTP and pectoralis major myocutaneous flap can be used to repair the tissue defects after radical resection of oral cancer, which can effective improve the postoperative appearance, language and masticatory function of oral cancer patients. However, pectoralis major myocutaneous flap has easier operation and shorter operation time while ALTP can significantly reduce the incidence of postoperative complications with higher safety.

scholarly journals Effect of Methylxanthines (Coffee/tea Consumers) on Oral Precancer and Oral Cancer Patients with Smoking and Smokless Tobacco Habits

2012 ◽  
Vol 13 (6) ◽  
pp. 745-748 ◽  
Author(s):  
Bijle Mohammed Nadeem Ahmed ◽  
Yasmeen F Zubairy ◽  
Vinayak W Patil ◽  
Tabita Benjamin ◽  
Daya Jangam
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Smokeless Tobacco ◽  
Biochemical Parameters ◽  
Control Group ◽  
Study Group ◽  
Oral Precancer ◽  
Whole Saliva ◽  
Oral Cancer Patients ◽  
Submucous Fibrosis

ABSTRACT Aim To study, whether the consumption of regular tea/coffee (methylxanthines) increases the risk of oral cancer in patients with smoking and smokeless tobacco habits. Materials and methods This study was conducted on a total of 90 oral cancer and precancerous patients, from western Maharashtra (India) males in the age group of 20 to 45 years who were with smoking and smokeless tobacco habits; also regular tea/coffee consumers were subjected to biochemical parameters such as aspartate transaminase (AST) and alanine transaminase (ALT) from saliva and serum of patients with oral precancer (submucous fibrosis, leukoplakia) and oral cancer patients and compared with 90-age and sex-matched controls. Individuals consent was taken to measure their biochemical parameters, by using Hafkenscheid method in whole saliva and serum. Statistical analysis of variance (ANOVA) with Tukey's correction for multiple group comparisons was performed using Student t-test. Results Results show, that a statistically significant increase in value (p < 0.05) in ALT, AST in both saliva and serum was observed in precancerous and oral cancer patients among the study group as compared to the control group. Conclusion In the present study, there was increase in the levels of ALT, AST enzymes in both saliva and serum levels in the study group as compared to the control group which was statistically significant (p < 0.05) suggesting that long-term exposure of methylxanthines results in impairment of salivary gland antioxidant system which may affect the anticarcinogenic action of saliva. Clinical significance Oral fluids may be utilized effectively to study the variations in the biochemical constituents of saliva of leukoplakia, submucous fibrosis and oral cancer patients. How to cite this article Zubairy YF, Patil VW, Benjamin T, Jangam D, Bijle MNA, Patil S. Effect of Methylxanthines (Coffee/ tea Consumers) on Oral Precancer and Oral Cancer Patients with Smoking and Smokless Tobacco Habits. J Contemp Dent Pract 2012;13(6):745-748.

ELEMENTAL ANALYSIS OF BLOOD IN ORAL CANCER

2002 ◽  
Vol 12 (01n02) ◽  
pp. 41-46 ◽  
Author(s):  
T. R. RAUTRAY ◽  
V. VIJAYAN ◽  
P. K. HOTA
Keyword(s):  
Trace Elements ◽  
Oral Cancer ◽  
Cancer Patients ◽  
Epidemiological Studies ◽  
Spectroscopic Technique ◽  
Control Group ◽  
Carcinogenic Effect ◽  
Carcinogenic Agents ◽  
Oral Cancer Patients ◽  
Oral Malignancies

Fluctuations of the concentration levels of trace elements play an egregious role in enhancing carcinogenic effect in healthy persons and in the pathogenesis of oral malignancies. Epidemiological studies regarding the role of external carcinogenic agents in oral cancer have documented the involvement of certain trace elements either directly or indirectly. An analysis of trace elements like K, Ca, Fe, Cu, Zn, Se And Pb was done in seventeen oral cancer patients having tobacco habits by drawing their whole blood and determining their concentrations using Energy Dispersive X-ray Fluorescence (EDXRF) spectroscopic technique at Institute of Physics. Bhubaneswar, India which is rapid, efficient, multi-elemental and non-destructive in nature and in principle sensitive to all elements from Na to U. Fifteen healthy non-cancerous persons with tobacco habits were also taken as control. The results of the study group when compared with the control group illustrated that K, Cu and Se concentrations were significantly higher in the oral cancer patients as an effect of deleterious tobacco upon their blood whereas the rest of the elements like Ca, Zn, Fe and Pb did not reveal significant changes.

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