scholarly journals An observational study of effect of Mullerian anomalies on pregnancy

Author(s):  
Neha Raj ◽  
Niranjan N. Chavan

Background: Mullerian anomalies occur in approximately 3-4% of fertile and infertile women, 5–10% of women with recurrent early pregnancy loss, and up to 25% of women with late first or second-trimester pregnancy loss or preterm delivery. However, due to low prevalence rate and asymptomatic course of the anomalies, Mullerian anomalies remain underdiagnosed and often overlooked as a possible cause of recurrent pregnancy failures, preterm deliveries, IUGR and low birth weight.Methods: Total of 30 cases of Mullerian anomalies with pregnancy, prior diagnosed or incidental during LSCS, were studied for complications during pregnancy, history of gynecological complaints and rate of diagnosis with routine imaging technique.Results: Septate uterus was the most common anomaly seen in this study (36.6%).56.6% were diagnosed incidentally during LSCS despite the fact 26.6% of cases had history of 2 or more abortions and 30% had some or other gynecological complaints previously. 10% of pregnancies ended in abortions, 20% had preterm delivery, 36.6% had malpresentations and there was case of rupture uterus (03.3%).Conclusions: Mullerian anomalies are often asymptomatic or have subtle gynecological symptoms which are often missed by both patient and gynecologists. It is observed that due to the asymptomatic course of Mullerian anomalies, invasive nature of HSG and lack of 1.5 Tesla MRI at many institutes leads to low rate of diagnosis of Mullerian anomalies. Pregnancy with Mullerian anomalies often have preterm delivery, IUGR and malpresentation, so, require proper counselling and close monitoring during antenatal period.

2020 ◽  
Vol 136 (6) ◽  
pp. 1232-1232
Author(s):  
Simone Garzon ◽  
Antonio Simone Laganà ◽  
Amerigo Vitagliano ◽  
Sergio Haimovich ◽  
Luis Alonso Pacheco ◽  
...  

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
J Malhotra ◽  
N Malhotra ◽  
N Malhotra

Abstract text Mullerian Anomalies are present in approximately 5% to 7% of the general population and the incidence is a little more in infertile and recurrent miscarriage women. Most of the recent studies have reported that the obstetric outcome is compromised in this group with greater risk of infertility, recurrent pregnancy loss, intrauterine growth retardation, preterm birth and many other obstetric complications, which may be individually related to the different types of Mullerian Anomalies. In this presentation, We are going to discuss on how the outcomes are different in the various Mullerian Anomalies depending upon the degree of the defects related to different complications with more profound defects. We will also discuss on how to optimize the pregnancy outcomes with various interventions and what the literature review supports. Trial registration number Study funding Funding source


2003 ◽  
Vol 55 (3) ◽  
pp. 186-188 ◽  
Author(s):  
Mohammad Fatum ◽  
Nathan Rojansky ◽  
Asher Shushan

2021 ◽  
Vol 3 (Number 1) ◽  
pp. 38-40
Author(s):  
Nusrat Mahjabeen ◽  
Shaikh Zinnat Ara Nasreen

Cervical incompetence is characterized by painless dilatation of the incompetent cervix and results in miscarriages and preterm delivery during second trimester. Cervical cerclage (CC) has been utilized for the cure of loss in second trimester pregnancy. The detection of cervical incompetency is difficult. Usually patients have history of repeated second trimester demise or early preterm delivery after cervical dilatation without pain having no bleeding, contractions, or other reasons. We report a 28years old patient, 3rd gravida, para 0+2, at 11 weeks’ gestation with the diagnosis of cervical incompetence, in whom cervical cerclage (McDonald’s suture) was performed successfully. There were no operative or immediate postoperative complications. A healthy infant was delivered at 37 weeks by caesarean section. After delivery the suture was removed. Cervical cerclage during pregnancy can be safe and effective treatment for well-selected patients with cervical incompetence.


2021 ◽  
Vol 74 (6) ◽  
pp. 1355-1359
Author(s):  
Aidyn G. Salmanov ◽  
Oleg M. Ishchak ◽  
Yuliia M. Shostak ◽  
Viktoriia V. Kozachenko ◽  
Victor O. Rud ◽  
...  

The aim: To find out whether or not the presence of pregnancy loss and preterm birth was associated with the history of healthcare-associated infection (HAI) of women reproductive tract. Materials and methods: We performed a retrospective cohort study was based on surveillance data. This study included 1,027 fertile women aged 21-50 years admitted to 8 hospitals from 2017-2019 with complaints to pregnancy loss or preterm birth. Definitions HAI of women reproductive tract were used from the CDC/ NHSN. Results: Of 1,027 fertile women with complaints to pregnancy loss or preterm birth, 702 (68.4%) HAIs of reproductive tract were detected. The predominant HAIs were: postpartum endometritis (19.1), bacterial vaginitis (15.8%), chorioamnionitis (11.3%), vaginal cuff infection (9.1%), and parametritis (5.6%). According to the statistical data, a significant association between HAI of women reproductive tract and the history of pregnancy loss (p < 0.05) was determined. The presence of HAI had no effect on the first trimester miscarriage (p > 0.05), but HAI women reproductive tract had strongly affected the second trimester pregnancy losses (p < 0.05). Main causative agents of HAI were Escherichia coli (31.5%), Enterobacter spp. (18.4%), Klebsiella pneumoniae (12.5%), Enterococcus faecalis (11.6%),Staphylococcus aureus (10.2%), Pseudomonas aeruginosa (8.4%). Conclusions: This study identified a significant association between healthcare-associated infection of women reproductive tract and a history of miscarriage. However, there was no association between HAI and a history of preterm birth.


2021 ◽  
pp. 47-49
Author(s):  
Amita Yadav ◽  
Archana Kumari ◽  
Anupama Gupta

Objective: To diagnose the various types of Mullerian abnormalities using different modalities and to nd out its prevalence among infertile women. Method: A prospective study was conducted on 200 infertile women attending the outpatient and inpatient department of Obstetrics and Gynaecology in Swaroop Rani Nehru hospital and kamla Nehru Hospital of MLN medical College,Prayagraj during the year 2019-2020. Hysterosalpingography, 3 D ultrasonography and hysterolaparoscopy was used as diagnostic modalities to nd the prevalence of mullerian anomalies among infertile women of age group of 20 to 40 years. A total of 18 cases (9%) Results: were diagnosed to have mullerian anomalies which included 7 cases of partial septate uterus(3.5%), 2 cases (1%) each of complete septate,partial bicornuate and arcuate uterus respectively, 1 case(0.5%) each of agenesis, didelphys, complete bicornuate,unicornuate-non communicant and unicornuate without horn respectively. Conclusion: Prevalence of Mullerian anomalies in our study was 9% among infertile women, partial septate being the most common. Diagnostic hysterolaparoscopy was best investigation(sensitivity=100%, specicity=100%,PPV=100%,NPV=100%). 3D ultrasonography ,being non-invasive and more convenient was stongly comparable to hysterolaparoscopy( kappa value=0.906) than to hysterosalpingography( kappa value=0.660).


Diagnostics ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 149 ◽  
Author(s):  
Enrique Reyes-Muñoz ◽  
Salvatore Giovanni Vitale ◽  
Deisi Alvarado-Rosales ◽  
Esther Iyune-Cojab ◽  
Amerigo Vitagliano ◽  
...  

Background: To evaluate the prevalence of Müllerian anomalies (MAs) in a cohort of infertile Mexican women candidates for infertility treatments (intrauterine insemination or IVF (In vitro fertilization) cycles). Methods: We performed a retrospective observational study on a cohort of consecutive women, who underwent hysteroscopy and laparoscopy as part of the basic infertility workup from 2002 to 2014, at our center. Our aim was to calculate the prevalence of MAs and each subtype. Results: A total of 4005 women were included in the study. The MA prevalence was 4.4% (95% CI; 3.8–5.1; n = 177). Among women with MAs, the prevalence of different MA types was: septate uterus 54.2% (n = 96), arcuate uterus 15.8% (n = 28), bicornuate uterus 10.7% (n = 19), unicornuate uterus 8.5% (n = 15), didelphys uterus 6.2% (n = 11) and hypoplasia/agenesis 3.4% (n = 6), unclassifiable 1.1% (n = 2). Women with MAs who achieved pregnancy were: 33.3% (n = 59). The MA associated with the highest pregnancy rate was septate uterus after hysteroscopic correction, at 38.5% (37/96). Conclusions: The prevalence of MAs among infertile Mexican women can be considered as low, but not negligible. The septate uterus is the most common MA in women with infertility.


Author(s):  
Suman Choudhary ◽  
Prasuna Jelly ◽  
Prakash Mahala

Bicornuate uterus is a major cause of spontaneous abortion. The recurrent pregnancy loss has been reported to the range of 15% to 27%. There is different type of congenital uterine abnormalities like Bicornuate uterus, septate uterus, arcuate uterus, unicornuate uterus, didelphys uterus. It is important to consider this diagnosis in recurrent miscarriages, malpresentation, intra uterine growth restrictionand preterm deliveries. This report is about self at the age of 25-year-old pregnancy with a history of missed abortion. I was not diagnosing with a bicornuate uterus in my first pregnancy. However, I was diagnosed with a bicornuate uterus based on transvaginal ultrasound and hysterosalpingogram. A successful caesarean section was donein the 38th week of gestation. According to the results, successful outcome could be achieved with bicornuate uterus. The outcome of bicornuate uterus was successful.


2018 ◽  
Vol 03 (02/03) ◽  
pp. 184-188
Author(s):  
Indrani Garre ◽  
Lalita Nemani ◽  
Raju Nallagasu

Abstract Aim To observe the association of pregnancy-related factors on the incidence of cardiovascular disease (CVD). Introduction CVD is one of the leading causes of death in women. It really emphasizes the need for early recognition of cardiovascular risk in women. Heart disease in women poses a major challenge in that the first events are more likely to be fatal. Pregnancy itself predicts cardiovascular disease in later life and is a screening test for CVD. Methods Total 136 female patients from the outpatient clinic, as well as patients of our hospital, were included in our retrospective single-center study. Along with demographic data and details of risk factors, the reproductive history of all patients such as age at first pregnancy, number of children, any hormonal therapy, and mode and place of delivery were noted. Pregnancy-related data, such as the history of hypertension, diabetes, abortion, pregnancy loss; preterm delivery; and the weight of the newborn were taken into consideration. We excluded unmarried and nulliparous women. Results The study population comprised 136 female patients. There were 69 (50.74%) in group 1 (coronary artery disease [CAD] group) and 67 (49.36%) in group 2 (non-CAD group). Mean age of patients at enrollment was 53.2 ± 12.52 years. Twenty-seven (19.8%) patients fell under lost pregnancy or child category, and abortions and preterm delivery were faced in 26 (19.1%). Seventy-one (52.2%) patients attained menopause whereas hysterectomy was done in 35 (25.7%). The average age of hysterectomy was 38.37 ± 8.50 years, and that for menopause was 46.78 ± 5.04 years. During pregnancy, the history of hypertension was given only in 4 (3%), diabetes was in given none, and history of a low birth weight of the newborn was given in 3 (2.2%) women. The univariate analysis was done to see the statistical significance of mainly pregnancy factors on long-term cardiac outcomes along with risk factors. Generally, hypertension (p = 0.01) and diabetes (p = 0.01) had significance with cardiac outcomes. In spite of these, the history of a lost pregnancy/child and pregnancy complications both have shown near significance, that is, p = 0.06. Conclusion Our study suggests an impact of pregnancy loss irrespective of the etiology on the future cardiac outcomes as along with predominant impact factors of hypertension and diabetes.


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