scholarly journals Fine needle aspiration cytology as a first line investigation in cervical swellings of 470 cases

2018 ◽  
Vol 6 (10) ◽  
pp. 3385
Author(s):  
Bhavna G. Gamit ◽  
Mubin I. Patel ◽  
Mandakini M. Patel ◽  
Sharmistha M. Patel
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Invasive Technique ◽  
First Line ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology ◽  
Reactive Hyperplasia

Background: Fine needle aspiration cytology (FNAC) is a first line investigation in cervical swellings. The etiology varies from an inflammatory process to a malignant condition.Methods: The study was carried out in department of Pathology, Government Medical College, affiliated with government hospital in Gujarat. There were 470 patients with cervical swelling in a period from January 2017 to December 2017. Patients with thyroid swelling (swelling moves with deglutition) were excluded from the study. FNAC procedure was performed, smears prepared, stained with haematoxylin and eosin (H and E), May Grunwald Giemsa (MGG) and Pap stain. Zeihl Neelsen stain was carried out when required. Patient history, local examination findings and microscopic findings were recorded.Results: Total 470 patients, age ranged from 2 months to 90 years were studied. There were 286 males and 184 females. There were 449 cases in which conclusive opinion given. 111 cases were neoplastic and 338 cases were non-neoplastic. Various cytological diagnosis were; 207 cases of granulomatous lymphadenitis (tuberculosis), 1 case of filarial lymphadenitis, 72 cases of chronic reactive hyperplasia, 25 cases of acute suppurative inflammation, 1 case of sialadenitis, 10 cases of keratinous cyst, 6 cases of benign cystic lesion, 12 cases of lipoma, 4 cases of lymphoproliferative lesion, 1 cases of benign appendage tumor, 2 cases of mucoepidermoid carcinoma, 103 cases of metastasis and 5 cases of non Hodgkin lymphoma.Conclusions: FNAC is a simple, quick, inexpensive and minimally invasive technique to diagnose cervical swellings. It can differentiate the infective process from neoplastic one and avoids unnecessary surgeries.

scholarly journals Clinical profile of cervical lymphadenopathy and to find diagnostic efficacy of fine-needle aspiration cytology, ultrasonography and histopathological examination

2020 ◽  
Vol 6 (3) ◽  
pp. 551
Author(s):  
Nitin Sharma ◽  
Maya Singh ◽  
Pritosh Sharma ◽  
Rahul Nahar ◽  
V. P. Goyal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Tuberculous Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Cervical lymphadenopathy is the sign of a disease process which involves lymph nodes that are anomalous in uniformity and dimensions. It is very vital to exercise fine-needle aspiration biopsy, histopathological investigation, and ultrasonography for the diagnosis of palpable lesions.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study of 12-month duration from January 2018 to December 2018 in 61 patients presenting with cervical lymphadenopathy admitted in the ENT Department at Geetanjali Medical College and Hospital, Udaipur.  </p><p class="abstract"><strong>Results:</strong> In biopsy, most common diagnosis was chronic granulomatous lymphadenitis i.e. in 62.3% of the patients. As compared to biopsy, fine-needle aspiration cytology (FNAC) showed chronic granulomatous lymphadenitis in 46% of the patients, with overall sensitivity of 91.1%, and specificity of 60.0%. and accuracy of 88.5%. Whereas ultrasonography (USG) reported, 64% cervical lymphadenopathy in patients, with overall sensitivity came out to be 91.1%, specificity to be 40.0%, accuracy was 86.9%.</p><p class="abstract"><strong>Conclusions:</strong> Present study showed that biopsy is the gold standard procedure for diagnosis of cervical lymphadenopathy lesions followed by FNAC, USG. Tuberculous lymphadenitis was most common diagnosis made by the diagnostic modalities.</p>

scholarly journals Pattern of Lymphadenopathy on Fine Needle Aspiration Cytology in a Tertiary Level Hospital in Kathmandu

2018 ◽  
Vol 1 (2) ◽  
pp. 97-99
Author(s):  
Amar Narayan Shrestha ◽  
Shova Kunwar ◽  
Barun Babu Aryal ◽  
Anurag Adhikari ◽  
Ayusha Poudel
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Tertiary Level ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology ◽  
Tubercular Lymphadenitis ◽  
Level Hospital

Introduction: Fine Needle Aspiration Cytology is a relatively simple, inexpensive and rapid diagnostic procedure for identifying cause of lymphadenopathy without need for surgical procedures. This study aims to explain the pattern of lymphadenopathy seen on fine needle aspiration cytology in a tertiary level hospital in KathmanduMaterials and Methods: This study was conducted at Shree Birendra Hospital Nepal. Cases of lymph node FNAC done in the years 2073 and 2074 BS were included in the study. The cases were classified into reactive lymphadenitis, granulomatous lymphadenitis, tubercular lymphadenitis, lymphomas, leukemias, and metastases.Results: A total of 215 patients were included in the study, ranging in age from 2 to 84 years, out of which 98 were female and 117 were male. Reactive lymphadenitis was the most common diagnosis (n=126; 58.6%), followed by granulomatous lymphadenitis (n=34; 15.8%) and tubercular lymphadenitis (n=18; 8.4%). There were 18 cases of metastatic malignancies, 15 cases of suppurative lymphadenitis, and 2 cases of Hodgkin lymphoma and 2 cases of non-Hodgkin lymphoma.Conclusions: Reactive lymphadenitis is the most common type of lymphadenopathy encountered in FNAC, while in the elderly, metastases are more common.

scholarly journals Correlation of Fine Needle Aspiration Cytology and Histopathology of the Neck Swellings Presenting at National Academy of Medical Sciences, Kathmandu, Nepal

2017 ◽  
Vol 2 (2) ◽  
pp. 206-210
Author(s):  
Harihar Devkota ◽  
YC Sibakoti ◽  
S Menyangbo ◽  
S Basnet ◽  
MK Jha ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Gold Standard ◽  
Fine Needle Aspiration Cytology ◽  
Calculated Data ◽  
Needle Aspiration ◽  
Invasive Technique ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neck Masses ◽  
Needle Aspiration Cytology

IntroductionNeck masses are frequently found in clinical practice. A spectrum of pathological lesions ranging from inflammation to benign and highly malignant manifestation is observed. Fine needle aspiration cytology (FNAC) of neck masses is a quick, easy, safe and cheap technique in the diagnosis which has been a well-accepted procedure in diagnosing various swellings. Histopathology is a gold standard technique in diagnosing any swelling which also provide detail architecture, however it also requires OT setings, more manpower, expensive, time consuming, more traumatic and can sometimes become difficult.ObjectiveThe objective of our study was to evaluate the frequencies of neck swellings and how efficacy FNAC is in diagnosing neck masses by correlating the gold standard histopathological examination.MethodologyA Hospital based descriptive cross sectional prospective study was conducted in 50 patients with neck swellings presenting in the surgery OPD and admitied patient for some other reasons. FNAC and histopathological examinations were done from those lesions and were compared. The sensitivity, specificity and accuracy rates were calculated. Data entry and analysis was performed using SPSS.ResultsA total of 50 patient were subjected to both FNAC and histopathology examination (HPE). Out of 50 cases, 25 were male and 25 were female. The age ranged from 16 to 82 years. Lymph nodes 22 (44%) was the most common case, followed by thyroid 17 (34%), salivary glands 10 (20%) and soft issue 1 (2%).Among all Tubercular lymphadenitis (18%) followed by papillary carcinoma of thyroid (14%),metastatic carcinoma of lymph node, NHL, and pleomorphic adenoma 10% each. The sensitivity of FNAC in diagnosing neck masses is 90.08%, specificity is of 98.53%, and diagnostic accuracy is of 87.64%.ConclusionFNAC is a simple, fast, inexpensive, and minimally invasive technique which can be used as the first line investigation in diagnosing neck swellings.Birat Journal of Health SciencesVol.2/No.1/Issue 2/ Jan - April 2017, page: 206-210

scholarly journals The role of core needle biopsies in the management of neck lumps

2019 ◽  
Vol 101 (3) ◽  
pp. 193-196
Author(s):  
A Kalra ◽  
G-M Prucher ◽  
S Hodges
Keyword(s):  
Fine Needle Aspiration ◽  
Core Needle Biopsy ◽  
Fine Needle Aspiration Cytology ◽  
Needle Biopsy ◽  
Needle Aspiration ◽  
Invasive Technique ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Introduction King’s College Hospital has proudly provided a one-stop neck lump clinic since 2012. These multidisciplinary clinics allow for rapid diagnoses due to in-clinic investigations. In April 2013, ultrasound-guided core needle biopsies were introduced as an alternative/adjunct to fine-needle aspiration cytology and open biopsies for obtaining histological diagnoses. The aim of the study was to assess the impact of core needle biopsies on the diagnosis of neck lumps compared with fine-needle aspiration cytology and open biopsies between April 2015 and May 2016. Materials and methods Data were collected prospectively between April 2015 and May 2016 and analysed for numbers of fine-needle aspiration cytology, core needle biopsies and open biopsies performed and diagnoses made. Results A total of 190 patients were seen on the clinic; 51 had fine-needle aspiration cytology and 19 procedures gave a diagnosis. Of the remainder of these patients, 21 went on to have a core needle biopsy and 12 biopsies gave a diagnosis. An additional eight patients only had a core needle biopsy, of which five biopsies gave a diagnosis. Of the ten patients who had an open biopsy, four had a previous fine-needle aspiration cytology and core needle biopsy, three only a core needle biopsy, two had neither and one had fine-needle aspiration cytology. Conclusion The introduction of core needle biopsies has reduced the number of open biopsies performed. With increasing acceptance of this minimally invasive technique, core needle biopsies appear to be forming the key diagnostic investigation in patients with neck lumps.

scholarly journals Peripheral Lymphadenopathy in Children, Comparison of Fine Needle Aspiration Cytology with Open Biopsy

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Mukhtar Hussain ◽  
Akram Shad Chishti ◽  
Rubina Mukhtar ◽  
Hanif Khan ◽  
Hussain Siddiqui ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Clinical Findings ◽  
Paediatric Surgery ◽  
Open Biopsy ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Reactive Hyperplasia

Objective: To compare the results of Fine Needle Aspiration Cytology (FNAC) with open biopsy in cases of Peripheral Lymphadenopathy. Design: A comparative study. Place and duration of study: Department of Paediatric Surgery & Department of Pathology, Nishtar Medical College & Hospital, Multan from January 2004 to September 2004. Subjects and methods: Patients presenting with Peripheral Lymphadenopathy in Paediatric Surgery out patient department were included in study. Relevant history and clinical findings were entered in performa and patients were submitted to investigations like FNAC and open lymphnode biopsy, after getting consent, on OPD basis. Results: Results of both FNAC and histopathology in 54 patients were available for comparison at the end of study. FNAC showed tuberculosis in 36 (66.67%), lymphoproliferative process in 16 (29.63%) and poor yield in 2 (3.71%) cases. Whereas open lymphnode biopsy on histopathology confirmed tuberculosis in 42 (77.78%), Hodgkin`s lymphoma in 4.(7.42%), Non Hodgkin`s in 6 (11.13%) and reactive hyperplasia in 2 (3.71%) cases. Sensitivity of FNAC in tuberculosis was 85.7% with a specificity of 100% in cases of tuberculosis while it was 71.5% in cases of lymphomatous process with an overall sensitivity of 78.5% in peripheral lymphadenopathy. Conclusion: In our setup lymphnode biopsy should be performed in all suspected cases to avoid long term morbidity and mortality especially in clinically malignant illnesses.

scholarly journals Fine needle aspiration cytology of thyroid swellings: Experience in a tertiary care hospital of Nepal

2012 ◽  
Vol 18 (2) ◽  
pp. 119-123
Author(s):  
R Nepali ◽  
G Banita ◽  
G Thakur
Keyword(s):  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Invasive Technique ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neoplastic Lesions ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

Introduction: Fine Needle Aspiration Cytology (FNAC) being a minimally invasive technique, is particularly suitable in the sensitive neck area. FNAC can obviate the need for surgery if the lesion is shown to be non neoplastic or if it confirms suspected recurrent tumor. A preoperative cytological diagnosis of a primary neoplasm of thyroid may allow more rational    planning of surgery.Method: This descriptive observational study was carried out at the Department of ENT- Head & Neck Surgery, Gandaki Medical College and Charak Hospital, Pokhara, Nepal, from August 2010 to November 2011. A total of 154 consecutive FNAC of thyroid swellings was included.Results: Out of 154 patients female were 142 (92%) and men were 12 (8%). In this series of 154 thyroid swellings on FNAC one hundred and thirty six (88%) were non neoplastic and eighteen (12%) neoplastic. Among non neoplastic thyroid swelling, adenoma was the most common sixty two (40%), followed by colloid cyst, Hashimoto thypoiditis, subacute thyroiditis, adenoma, cystic lesion, Graves’s disease, thyroglossal cyst and lymphocytic thyroiditis. Among neoplastic thyroid swelling papillary carcinoma was the commonest nine (5.8%) followed by follicular neoplasm six (3.9%).Conclusion: It is concluded from the present study that female in our region were more affected, non-neoplastic lesions of the thyroid were more common (colloid goiter being the commonest) than neoplastic lesions (papillary carcinoma being the commonest). DOI:http://dx.doi.org/10.3329/bjo.v18i2.11984 Bangladesh J Otorhinolaryngol 2012; 18(2): 119-123    

scholarly journals Reliability of FNAC as a diagnostic tool in lymphadenopathy

2017 ◽  
Vol 4 (4) ◽  
pp. 1073
Author(s):  
Sheela K. M. ◽  
Priya M. G.
Keyword(s):  
Lymph Node ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
First Line ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Clinical Presentations ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology is a first line investigation modality for the evaluation of cervical lymphadenopathies. Cervical lymphadenopathy is one of the most common clinical presentations affecting all age groups. Fine needle aspiration cytology is a first line investigation modality for the evaluation of cervical lymphadenopathies. Cervical lymphadenopathy is one of the most common clinical presentations affecting all age groups.Methods: This study was carried out in the Department of Pathology of Government Medical College Thiruvananthapuram over a two year. Out of 1020 aspirations 122 cases where identified and included in the study. All the diagnosis obtained by fine needle aspiration cytology was correlated with histopathology.Results: The age of the patients ranged from seven years to seventy-eight years in which 44% were males and 56% were females. Incidence of non-neoplastic lymph node lesions was common during 2 to 4 decades. Incidence of neoplastic lymph node lesions was common during 4 to 6th decade. Reactive change and Tuberculosis were seen more common in females whereas Non-Hodgkin’s lymphoma and metastatic tumors were more common in males. The overall accuracy of lymph node lesions in our study was found to be 90.98%, sensitivity 84 % and specificity 95.8%.Conclusions: Our study concluded that FNAC is simple, quick, minimally invasive technique to diagnose lymphadenopathy. The overall accuracy of lymph node lesions in our study was found to be 90.98%, sensitivity 84% and specificity 95.8%. Findings in this study are comparable and consistent with studies conducted elsewhere. The limitations of FNAC are that only positive results have clinical significance. The limitations have to be taken into account while interpreting the smears and skill has to be gained by constant practice.

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