scholarly journals Utilization of fresh frozen plasma in a tertiary care hospital in central Kerala

Author(s):  
S. N. Sreelekshmi ◽  
Lekshmidevi . ◽  
G. Rajan ◽  
M. S. Suma

Background: The demand for blood and its components always exceeds the supply in our health care setting. Hence there is a need to prioritize the usage of these components. An audit makes this possible. The present study is conducted on utilization of Fresh frozen plasma which is one of the most requested blood components.Methods: The study was conducted on the first 241 FFP transfusions during the study period of 1 year. Requisition forms for issuing FFP from various departments were reviewed and relevant data collected. Patients’ case record was also retrieved to collect data related to the transfusion episodes. The data collected were compiled, coded and expressed using descriptive statistical tools like mean, mode, percentage and ratio using Microsoft Excel 2010.Results: Most of the patients who underwent FFP transfusion were males and in the age group 60-70. Most of the requests for FFP issue came from Cardiothoracic department. Most common indication for FFP transfusion was raised PT INR. FFP units remained unutilized in CTVS, General surgery and general medicine. 20% of the received request forms were incompletely filled with the Clinical diagnosis and Indication for FFP being most frequently omitted information.Conclusions: Various departments at Government Medical College, Kottayam are efficiently utilizing FFP. But more intervention is needed in addressing issues related to the sending of requisition forms and ensuring adequate usage of FFP to prevent its wastage.

Hematology ◽  
2012 ◽  
Vol 17 (5) ◽  
pp. 306-310 ◽  
Author(s):  
Sangeeta Pahuja ◽  
Neha Sethi ◽  
Smita Singh ◽  
Sunita Sharma ◽  
Manjula Jain ◽  
...  

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 4184-4184
Author(s):  
Kamran Darabi ◽  
Lynne Uhl

Abstract INTRODUCTION: Various guidelines define appropriateness of FFP administration based on prothrombin time (PT) greater than 1.5 times normal. However, FFP is often transfused to patients with PTs that are in the upper range of normal or mildly prolonged. There is a paucity of data on whether transfusion of FFP to such patients will change their PT. METHODS: We retrospectively reviewed all FFP transfusions that were administered to patients with a PT below 17 seconds (normal reference range 11.3–13.6 seconds) at a tertiary care hospital in 2004. Patients were included in our analysis if their PT was measured prior to and within six hours of transfusion and if they received no more than two units of FFP. We identified 143 consecutive cases that met these criteria. RESULTS: 66 patients received one unit and 77 patients received 2 units of FFP. The median decrease in PT after the infusion of one or two units of FFP was 0.4 seconds and 0.6 seconds respectively. The pretransfusion PTs in 6 patients ranged between 12.2–13 seconds (subgroup 1), in 17 patients 13–14 seconds (subgroup 2), in 46 patients 14–15 seconds (subgroup 3), in 37 patients 15–16 seconds (subgroup 4), and in 37 patients 16–17 seconds (subgroup 5). Patients in subgroups 1 and 2 were noted to have higher PT values after the administration of FFP (median prolongation of 0.6 and 0.1 seconds respectively). The PT shortened in subgroup 3 by 0.4 seconds (median) and in subgroups 4 and 5 by 0.9 seconds (median) when compared to the pretransfusion PT, which represent clinically insignificant corrections. CONCLUSION: Transfusion of blood products is not without risks; given that PT values of less than 17 seconds do not significantly change following transfusion of one to two units of FFP, this clinical practice should be avoided.


2007 ◽  
Vol 82 (12) ◽  
pp. 1091-1094 ◽  
Author(s):  
Bulent Ozgonenel ◽  
Barbara O'Malley ◽  
Priya Krishen ◽  
A.B. Eisenbrey

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