scholarly journals Vacuum assisted closure versus total contact casting in the healing of plantar foot ulcers: a comparative prospective study

2019 ◽  
Vol 6 (9) ◽  
pp. 3152
Author(s):  
Srikanth Reddy Challapalli ◽  
Theja Peddavenkatagari ◽  
Chanda Sukanya ◽  
Venkataprakash Gandikota ◽  
Praveena Srimanthula Venkata ◽  
...  
Keyword(s):  
Prospective Study ◽  
Hospital Stay ◽  
Foot Ulcers ◽  
Vacuum Assisted Closure ◽  
Effective Work ◽  
Wound Size ◽  
Returns To Work ◽  
Total Contact Casting ◽  
Group B ◽  
Comparative Prospective Study

Background: The objective of the study was to compare the effectiveness of vacuum assisted closure (VAC) and total contact casting (TCC) in the healing of plantar foot ulcers. Chronic leg ulcers are a significant cause of morbidity in developing countries like India, leading to excessive health care expenses and loss of effective work hours, inspite of availability of various novel modalities of management. This study aims to compare the effectiveness of vacuum assisted closure and total contact casting in the healing in plantar foot ulcers, in order to standardise a procedure with maximum benefits.Methods: This comparative prospective study was conducted on 150 individuals admitted to SVRRGG Hospital, Tirupati, with the diagnosis of plantar foot ulcers from august 2017 to march 2019. They were divided into 2 groups, Group A (75 patients treated with VAC) and Group B (75 patients treated with TCC). In this study, the outcomes assessed were reduction of wound size and length of hospital stay.Results: In this study, mean reduction of wound surface area with VAC and TCC was 21.09 and 12.83 respectively, mean percentage of reduction of wound size with VAC is 90.43 and in TCC was 52.36. Mean hospital stay with VAC and TCC was 24.90 days and 51.29 days respectively.Conclusions: VAC is more effective than TCC in the treatment of foot ulcers, with less duration of hospital stay and earlier returns to work.

Comparison of 3% saline and 0.9% normal saline nebulization as diluent in children with bronchiolitis

2020 ◽  
pp. 1-10
Author(s):  
Shobha Sapkota ◽  
Ammara Kaleem ◽  
Suffura Huma ◽  
Muhammad Aleem Ud-Din ◽  
Shabbir Ahmad ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Prospective Study ◽  
Hospital Stay ◽  
Normal Saline ◽  
Saline Solution ◽  
Length Of Hospital Stay ◽  
Group A ◽  
Key Words 3 ◽  
Group B ◽  
Mean Time

Abstract Objective: To compare the outcome in terms of mean time to disappearance of cough, wheezing, crackles and length of hospital stay in patients treated with sodium chloride 3% with sodium chloride 0.9% as nebulisation diluent in children for suffering from bronchiolitis. Methods: The prospective study was conducted at the Department of Paediatric Medicine Sheikh Zayed Hospital, Lahore, Pakistan, from November 2014 to April 2015, and comprised children aged between 6 weeks and 24 months having bronchiolitis. Group A received 3% sodium chloride and Group B received 0.9% of the same solution. Duration of cough, wheezing, crackles and duration of stay at hospital were compared between the groups. Data was analysed using SPSS 17. Results: Of the 100 patients, there were 50(50%) in Group A with a mean age of 7.17±4.46, and as many in Group B with a mean age of 6.6±3.74. Overall, there were 55(55%) boys and 45(45%) girls. Mean cough and wheezing remission time as well as length of hospital stay was significantly different between the groups (p<0.05). Conclusion: In children having bronchiolitis, 3% saline as nebuliser solution was found to be more effective than 0.9% saline solution. Key Words: 3% saline solution, Bronchiolitis, Wheezing, Crepitations, Hospital stay.

scholarly journals Comparison of modified vacuum dressing and wet normal saline dressing in treatment of non-healing diabetic foot ulcers

2019 ◽  
Vol 6 (8) ◽  
pp. 2772
Author(s):  
Muhammed Muneer ◽  
Thomas K. Thomas ◽  
Dayananda Babu ◽  
Deepak Paul
Keyword(s):  
Hospital Stay ◽  
Diabetic Foot ◽  
Financial Burden ◽  
Large Population ◽  
Healing Time ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Group A ◽  
Group B ◽  
The Cost

Background: Diabetic foot a complication of diabetes can lead to significant morbidity and have financial burden. The standard of dressing diabetic foot ulcers has been saline dressings. Negative pressure vacuum devices have come and had a significant impact on treatment of diabetic ulcers. But in developing countries the cost associated with it makes it inaccessible to a large population. Our study aims to compare the use of modified vacuum dressing against saline dressing and compare healing rates, costs involved and hospital stay of patients.Methods: Our study was prospective study of 80 patients randomised into two groups, of 40 each. Group A consisted of patients with modified vacuum dressing and group B with wet saline dressing. Simple randomisation technique was used. They were compared for healing rates, hospital stay and cost involved.Results: There was a 43.75% decrease in area of the ulcer in group A compared to 25.15% in group B after 4 weeks. Decrease in wound depth was 55.41% and 26.94% in group A and B respectively. The mean hospital stay was 33.18 days in group A compared to 45.58 days in group B. The average cost incurred for patients in group A was rupees 14,381 compared to 19,465 rupees in group B.Conclusions: From our study we found that modified vacuum dressing in spite of being cheap it reduces healing time, hospital stay there by the cost incurred to patients. So we recommended modified vacuum dressings as a go to method of treating diabetic foot ulcers.

scholarly journals Drain fluid amylase in defining clinically relevant postoperative pancreatic fistula following pancreaticoduodenectomy: day 5 is better than day 3

2017 ◽  
Vol 4 (12) ◽  
pp. 4058
Author(s):  
Venkatarami Reddy Vutukuru ◽  
Sivarama Krishna Gavini ◽  
Chandramaliteeswaran C. ◽  
Dinakar Reddy A. ◽  
Varun Dasari ◽  
...  
Keyword(s):  
Prospective Study ◽  
Hospital Stay ◽  
Pancreatic Fistula ◽  
Postoperative Pancreatic Fistula ◽  
P Value ◽  
Duration Of Hospital Stay ◽  
Drain Fluid ◽  
Group A ◽  
Group B ◽  
Better Than

Background: Postoperative pancreatic fistula (POPF) remains the most serious complication of Pancreaticoduodenectomy. ISGPF defined POPF in 2005 based on drain fluid amylase on or after day 3 and graded the severity. But as Grade A fistulas are not clinically relevant, most of the clinicians do not consider them as POPF. Hence exact incidence of POPF is not known. Our aim is to see weather drain fluid amylase on or after day 5 can define clinically relevant POPF better than day 3.Methods: Prospective study included all patients who underwent Pancreaticoduodenectomy during the period January 2013 to November 2016. Serum and Drain fluid amylase were analyzed on Day 3. Those who met criteria of POPF underwent repeat amylase on Day 5. These patients were divided into 2 groups. Group A includes patients whose Day 5 amylase normalized and Group B where elevated Amylase persisted. Outcomes were compared in 2 Groups in terms of clinically relevant POPF (CRF), DGE, Haemorrhage (PPH), hospital stay and 30 Days mortality. Results were analysed and p value <0.05 was considered significant.Results: On 110 patients, 44 (40%) met ISGPF criteria of POPF. Of 44, 36 (82%) had normalized Amylase on Day 5 (Group A). Only 8 (18%) had persistent elevated amylase (Group B). None in Group A had CRF, whereas in Group B, 6(75%) had CRF and 2(25%) had only biochemical leak (p<0.0001). DGE was significantly higher in Group B (87.5% vs. 33.3%; p=0.013). PPH was seen in only 1 patient (Group A). Duration of hospital stay and 30day mortality were similar.Conclusions: Drain fluid amylase levels on or after Day 5 defines clinically relevant POPF better than levels on or after day 3.

scholarly journals A prospective study on effectiveness of use of papain urea based preparation in dressings compared with regular conventional dressings in diabetic foot ulcers

2017 ◽  
Vol 4 (6) ◽  
pp. 1984 ◽  
Author(s):  
Balasubrahmanya K. S. ◽  
Praveen M. Pawar ◽  
Srinidhi M. ◽  
Shruthi S. ◽  
Jinumon K. V. ◽  
...  
Keyword(s):  
Prospective Study ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Necrotic Tissue ◽  
Group A ◽  
Group B ◽  
A Prospective Study

Background: Diabetic foot ulcer is a very common condition encountered in surgical practise. Wound management pose a good challenge for a treating surgeon due to its physical, mental and social implications. The devitalised necrotic tissue present in ulcer does not favour the wound healing as it increases the chance of infection and delays appearance of granulation tissue. Hence debriding of devitalised tissue plays a key role in wound care. In present study ,we used papain urea based preparation in dressings which is a autolytic agent. This study was conducted to evaluate the effectiveness of use of papain urea based preparations compared with regular conventional dressing in diabetic foot ulcer management.Methods: This was a prospective study conducted in K. R. Hospital, Mysore, Karnataka, India. 60 eligible subjects with diabetic foot ulcers were selected and subjects were randomly allocated into two groups Group A and Group B with 30 subjects in each group. Subjects in Group A underwent dressing with papain urea based preparation and in Group B underwent regular conventional dressing. Results were assessed with respect to percentage decrease in necrotic tissue, incidence of infection, appearance of granulation and hospital stay.Results: Among Group A subjects percentage reduction of necrotic tissue was more, granulation appeared early and the hospital stay was less compared to Group B subjects which were statistically significant. However, there was no significant difference with respect to incidence of infection in both groups.Conclusions: Papain urea based preparation is effective in diabetic foot ulcer care.

scholarly journals Is vacuum assisted closure dressing better than conventional management of diabetic wounds?

2018 ◽  
Vol 5 (6) ◽  
pp. 2199
Author(s):  
Abhijit Bagul ◽  
Nandkishor Narwade ◽  
Ankit Bhupatkar ◽  
Sridevi Murali ◽  
Yashraj Shah
Keyword(s):  
Granulation Tissue ◽  
Foot Ulcers ◽  
Vacuum Therapy ◽  
Vacuum Assisted Closure ◽  
Prolonged Length ◽  
Early Appearance ◽  
Patients With Diabetes ◽  
Group A ◽  
Group B ◽  
Diabetic Wounds

Background: Foot ulcers are a major cause of hospitalization in patients with Diabetes Mellitus (DM) which increases hospital stay because of multiple surgical procedures, prolonged length of stay. The objectives of this study were to test the conventional therapy for diabetic wounds with respect to time and wound healing, to compare the outcomes of the two methods after a stipulated period and to prove the efficacy of one method over the other by appropriate statistical methods at the end of data collection.Methods: A prospective randomized hospital based observational study of 47 patients was conducted at the Hospital of D. Y. Patil University School of Medicine, Nerul, Navi Mumbai, Maharashtra, India for a period of 24 months (June 2014 to June 2016). All these 47 patients were studied, and the data was statistically evaluated to determine the efficacy of vacuum assisted closure in healing of diabetic wounds and to compare it with conventional method of treatment of diabetic wounds. The patients were divided into 2 groups, Group ‘A’ which consisted of 22 who received Vacuum Therapy (VAC), Group ‘B’ which consisted of 25 and received conventional dressing.Results: The patients on VAC therapy had early appearance of granulation tissue as compared to patients treated by Conventional dressing (90.9% Vs 76% at the end of one week. All patients developed granulation tissue by the end of 2 weeks.Conclusions: We thus conclude that VAC appears to be superior compared to conventional dressings in the treatment of diabetic foot ulcers in terms of early appearance of granulation tissue and decrease in wound depth.

scholarly journals A comparative study of vacuum assisted closure dressing with conventional dressings in the management of infected wounds

2020 ◽  
Vol 8 (1) ◽  
pp. 97
Author(s):  
Karanvir Singh ◽  
Gurlal Singh Puar ◽  
Vikas Kakkar ◽  
Rana Ranjit Singh
Keyword(s):  
Hospital Stay ◽  
Wound Management ◽  
Vacuum Assisted Closure ◽  
Average Hospital ◽  
Total Hospital Stay ◽  
Significant Difference ◽  
Infected Wounds ◽  
Group A ◽  
Group B ◽  
Day By Day

Background: In the whole world including India, incidence of infected wounds is increasing day by day. Trauma is the most common cause of wounds and number of other factors contribute to wound infection there on. Wound management and care thus carry an important role for such patients in the form of dressings, debridement etc. Many conventional dressings are being used these days, but vacuum assisted closure (VAC) dressing as widely gained acceptance now.Methods: Our study was conducted on 60 patients divided in 2 groups of 30 each to compare VAC dressing with conventional dressings.Results: There was significant difference in total hospital stay, no. of debridement done, granulation tissue fill up and graft take up in both groups, for example, the average hospital stay in group A was 21.8±7.61 and in group B was 26.47±9.55.Conclusions: So, VAC dressing was found to be more beneficial and patient friendly with lesser hospital stay and thus lesser cost than conventional dressings.

scholarly journals DIABETIC FOOT ULCERS;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
SOHAIL Farooq ◽  
Shaukat Javed ◽  
Nazish Jahan
Keyword(s):  
Granulation Tissue ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Wound Size ◽  
Group A ◽  
Group B

Introduction: Traditionally, moist dressings are being in used routinely by surgeons for management of diabetic foot ulcers. Recently, there is an encouraging trend of using VAC dressings in such patients. This study aimed to compare the outcome of VAC with moist dressing for management of diabetic foot ulcer. Study Design: Prospective randomized controlled trial. Setting: Department of Surgery, Al-Bukyriah General Hospital, Al-Bukayriah, Alqaseem KSA. Period: June 2012 to 07 December 2016. Methods and Material: 200 patients with diabetic foot ulcers. The patients were divided in two equal groups containing 100 patients each. In group A, 100 patients received VAC dressing treatment while in group B, 100 patients received wet dressings. Wound size, % reduction in wound size, appearance of granulation tissue and fate of wound were main outcome measured which were noted at start of study and at the end of study (4th week of therapy). Results: In group A, there were 73 (73%) men and 27 (27%) women with a mean age of 54.98+7.68 years and in group B, there were there were 75 (75%) men and 25 (25%) women with a mean age of 55.23+6.98 years. Size of wound before treatment in group A was 14.23± 6.78 cm2 which reduced to 5.11±1.91 cm2 at 4th wee and in group B it was 14.41±5.93 cm2 in the start which reduced to 11.29±3.63 cm2 at 4th week (p<0.05). Mean %reduction in wound size in group A was 63.22±9.19 and 22.92±7.18 in group B (p<0.05). In group A, 43 (43%) wounds healed spontaneously with shrinkage and group B only 2(2%) healed spontaneously (p<0.05). Conclusions: VAC therapy is superior to moist dressing in terms of achieving early granulation tissue, reduction in wound size and spontaneous wound shrinkage.

scholarly journals Outcomes of VAC versus conventional dressings in patients with lower limb ulcer

2018 ◽  
Vol 5 (5) ◽  
pp. 1792
Author(s):  
Hemant B. Janugade ◽  
Raunaq S. Chabbra ◽  
Ankur G. Das ◽  
Aniket Surushe ◽  
Harshvardhan Saygaonkar
Keyword(s):  
Hospital Stay ◽  
Lower Limb ◽  
Wound Management ◽  
Vacuum Assisted Closure ◽  
Duration Of Hospital Stay ◽  
Long Duration ◽  
Significant Burden ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Chronic leg ulcers are a significant cause of morbidity in developing countries causing a significant burden on the health care system. The orthodox methods of dressing the wound requires long duration of hospital stay. The recent technique of vacuum assisted closure (VAC) has brought about new horizons in wound management with better outcomes.Methods: A comparative randomized case control study was conducted with a total of 60 patients from November 2015 to December 2017 in patients admitted with lower limb ulcers to KIMSDU, Karad, Maharashtra.Results: The mean graft uptake of Group A(VAC) and Group B (conventional dressings) was 82.23±15.60 and 70.07±18.42 respectively. Healing was achieved in minimum of 11 days and maximum of 48 days in Group A and minimum of 22 days and maximum of 59 days in Group B. The mean duration of wound healing in Group A and Group B was 27.70±9.57 and 41.93±11.58 days respectively. The duration of hospital stay was minimum of 13 days and maximum of 50 days in Group A and minimum of 24 days and maximum of 60 days in Group B.Conclusions: Rate of granulation tissue formation, overall graft survival and patient compliance was better in vacuum assisted closure dressing group as compared to conventional dressing group. It was also seen that the overall hospital stay and post-operative complications were less in the vacuum assisted closure dressing group.

scholarly journals Stapled versus open haemorrhoidectomy: a prospective study

2020 ◽  
Vol 7 (11) ◽  
pp. 3740
Author(s):  
Serbin Mohammed ◽  
Kavitha Jayanthi Balachandran ◽  
S. Vineed ◽  
Meer M. Chisthi
Keyword(s):  
Prospective Study ◽  
Hospital Stay ◽  
Standard Procedure ◽  
Medical College ◽  
Early Return ◽  
Significant Difference ◽  
Lower Pain ◽  
Group A ◽  
Group B ◽  
A Prospective Study

Background: In this era of staplers and advanced techniques in surgery Milligan Morgan technique of open haemorrhoidectomy is still considered as gold standard procedure for symptomatic haemorrhoids. Stapler haemorrhoidectomy, even though it is practiced in many centres has not become common due to various factors. The present study was done to compare the efficacy, safety and advantages, if any, of the stapled haemorrhoidectomy to open procedure.Methods: This prospective study was performed in the department of general surgery, Government medical college, Thiruvananthapuram, Kerala over a period of 12 months from March 2015 to March 2016. Symptomatic patients with grade 3 and4 haemorrhoids were selected for the study. The patients were randomized into two equal groups of 20 each. Group A underwent conventional open haemorrhoidectomy and group B, stapled haemorrhoidectomy.Results: Mean operative time period for group A was 39.25 ±5.5 minutes and group B was 26.75±4.7 minutes. There was significant difference in the pain score between these procedures on first 3 post-operative days. There was also significant difference in group A and group B which was 6.55±1.099 and 3.55±0.759 days respectively for mean hospital stay and 9.90±1.651 and 5.70±0.865 days respectively for return to normal work.Conclusions: Stapler haemorrhoidectomy is associated with lower pain scores postoperatively and shorter duration of hospital stay with early return to work when compared to conventional open haemorrhoidectomy.

scholarly journals Prospective study of hair recovery after (neo)adjuvant chemotherapy with scalp cooling in Japanese breast cancer patients

2021 ◽  
Author(s):  
Shozo Ohsumi ◽  
Sachiko Kiyoto ◽  
Mina Takahashi ◽  
Seiki Takashima ◽  
Kenjiro Aogi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Prospective Study ◽  
Cancer Patients ◽  
Scalp Cooling ◽  
Breast Cancer Patients ◽  
Chemotherapy Infusion ◽  
Group A ◽  
Neo Adjuvant Chemotherapy ◽  
Group B

Abstract Purpose Scalp cooling during chemotherapy infusion to mitigate alopecia for breast cancer patients is becoming widespread; however, studies regarding hair recovery after chemotherapy with scalp cooling are limited. We conducted a prospective study of hair recovery after chemotherapy with scalp cooling. Patients and methods One hundred and seventeen Japanese female breast cancer patients who completed planned (neo)adjuvant chemotherapy using the Paxman Scalp Cooling System for alopecia prevention were evaluated for alopecia prevention in our prospective study. We evaluated their hair recovery 1, 4, 7, 10, and 13 months after chemotherapy. Primary outcomes were grades of alopecia judged by two investigators (objective grades) and patients’ answers to the questionnaire regarding the use of a wig or hat (subjective grades). Results Of 117 patients, 75 completed scalp cooling during the planned chemotherapy cycles (Group A), but 42 discontinued it mostly after the first cycle (Group B). Objective and subjective grades were significantly better in Group A than in Group B throughout 1 year, and at 4 and 7 months after chemotherapy. When we restricted patients to those with objective Grade 3 (hair loss of > 50%) at 1 month, Group A exhibited slightly faster hair recovery based on the objective grades than Group B. There was less persistent alopecia in Group A than in Group B. Conclusions Scalp cooling during chemotherapy infusion for Japanese breast cancer patients increased the rate of hair recovery and had preventive effects against persistent alopecia.

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