Morbidity profile and immediate outcome of late preterm neonates compared to term neonates in a rural tertiary care hospital of Gujarat

Background: Late premature infants are born near term, but are immature. As a consequence, late preterm infants are at higher risk than term infants to develop morbidities. Although late preterm infants are the largest subgroup of preterm infants, there is a very limited data available on problems regarding late preterm infants in rural India.Methods: This is a retrospective cohort study using previously collected data from neonates born at Dhiraj Hospital and neonates who were born outside but admitted at SNCU of Dhiraj Hospital, Piparia, Vadodara district, Gujarat, India between January 2015 to December 2015.Results: 168 late preterm infants and 1025 term infants were included in this study. The need for SNCU admission is significantly higher in late preterm compared to full term (41.07% vs 2.04%). Morbidities were higher in late preterm neonates compared to full term neonates. Sepsis (4.76% vs 1.07%), TTN (10.11% vs 2.04%), hyperbilirubinemia (19.04% vs 9.36%), RDS (1.78% vs 0.09%), hypoglycemia (1.78% vs 0.29%), PDA (1.78% vs 0.58%), risk of major congenital malformation (2.38% vs 0.58%). Need for respiratory support was 5.95% in late preterm vs 2.04% in full term neonates. Immediate neonatal outcome in terms of death and DAMA (non-salvageable) cases was poor in late preterm neonates compared to full term neonates (1.19% vs 0.78%).Conclusions: Late preterm neonates are at higher risk of morbidities and mortalities. They require special care. Judicious obstetric decisions are required to prevent late preterm births.

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Early neonatal morbidities in late preterm compared to term neonates born in a tertiary care private hospital

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20200680 ◽

2020 ◽

Vol 7 (3) ◽

pp. 565

Author(s):

Yogesh P. Mehta ◽

Manjusha Bhicurao Naik ◽

Kinnera Putrevu

Keyword(s):

Preterm Infants ◽

Tertiary Care ◽

Full Term ◽

Late Preterm ◽

Term Infants ◽

Term Neonates ◽

Late Preterm Infants ◽

Increased Risk ◽

Preterm Babies ◽

Term Newborns

Background: Late preterm babies, born between 34 completed weeks of gestation through 36 weeks 6/7 gestation, tend to be physiologically less mature than term infants, subjecting them to an increased risk of developing various morbidities. Limited information is available regarding the current scenario in India. Therefore, the objective of this study was to understand and compare the early morbidities in late preterm newborns with those in full term babies in a tertiary hospital in India.Methods: The current prospective, observational study consisted of total 150 babies divided into two groups equally; late preterm neonates born between 34 and 36 weeks of gestation and full-term neonates. Weight (at birth, at 72 hours), heart rate, temperature and respiratory parameters were noted of all babies. The newborns were examined for respiratory morbidities, ability to breastfeed, hypoglycemia, hypothermia, neonatal jaundice and signs of sepsis. The need for resuscitation, admission to neonatal intensive care unit (NICU) and parenteral nutrition was also assessed. Data was expressed as mean±SD and was analyzed using the Student ‘t’ and Mann Whitney U tests.Results: The mean length and weight at birth in late preterm babies was significantly lesser than term newborns. Late preterm babies were found to have significantly higher incidence of complications like hyperbilirubinemia (62.7% vs 13.3%), respiratory morbidities (16% vs 4%), poor feeding, hypothermia, hypoglycemia, and sepsis compared to term newborns (p<0.01).Conclusions: Late preterm infants are at a higher risk than term infants for a number of neonatal complications. Initiatives imparting special care to late preterm infants are required in order to lower the morbidities endured by this population.

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Morbidity and Mortality Outcome in Late Preterm Neonates at a Tertiary Care Hospital

Journal of Armed Forces Medical College Bangladesh ◽

10.3329/jafmc.v12i1.39966 ◽

2016 ◽

Vol 12 (1) ◽

pp. 44-47

Author(s):

Tahsinul Amin ◽

Ayesha Najma Nur

Keyword(s):

Preterm Infants ◽

Tertiary Care ◽

Late Preterm ◽

Morbidity And Mortality ◽

Respiratory Morbidity ◽

Preterm Neonates ◽

Care Hospital ◽

Term Neonates ◽

Late Preterm Infants ◽

Significant Difference

Introduction: The morbidity and mortality in late preterm neonates is higher than term neonates. The main reason is the relative physical and neurologic immaturity, though there is no significant difference in the weight or the size of the two groups. Objective: The study was conducted to compare the early neonatal morbidity and mortality (within first 7 days of life) in late preterm infants (34–36 6/7 weeks) with those in term neonates (37–41 6/7 weeks). Materials and Methods: This was a prospective study conducted from 01 January 2015 to 30 June 2015 in the department of Neonatology at a tertiary hospital. Results: Total 100 neonates were included in the study; fifty neonates in each group. Late preterm infants had significantly higher morbidity due to any cause, e.g. respiratory morbidity (p<0.05), jaundice (p<0.05), hypoglycemia (p<0.05), sepsis (p<0.05) and perinatal asphyxia (p<0.05). Early neonatal mortality in late preterm neonates was significantly higher than term neonates (p<0.05). Conclusion: Late preterm neonates are at high risk for morbidity and mortality as compared to term neonates. Journal of Armed Forces Medical College Bangladesh Vol.12(1) 2016: 44-47

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Early health issues in late pre-terms

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20190005 ◽

2019 ◽

Vol 6 (2) ◽

pp. 369

Author(s):

Monica Choudhary ◽

Kamna Jain

Keyword(s):

Preterm Infants ◽

Preterm Births ◽

Late Preterm ◽

Morbidity And Mortality ◽

Respiratory Morbidity ◽

Preterm Neonates ◽

Term Infants ◽

Term Neonates ◽

Late Preterm Infants ◽

Early Health

Background: Rates of preterm birth are increasing worldwide, mostly due to late preterm births (i.e. 34-36 6/7 weeks). The objective of the study is to calculate incidence of early morbidity and mortality in late preterm neonates (within first 7 days of life) compared with term neonates.Methods: It was a prospective cohort study. All live inborn late preterm infants (34 0/7 to 36 6/7 weeks) and term infants (37 0/7 to 41 6/7 weeks) who were born between November 2010 to October 2011. Study was done to find out early morbidity and mortality in late preterm births.Results: Present study included 256 late preterm infants and 498 term infants, amongst whom 95 (37.10%) late preterm and 98 (19.67%) term infants required NICU care (p<0.001). Late preterm infants were at significantly higher risk for overall morbidity due to any cause (P<0.001; Odds Ratio (OR):2.4; 95% CI: 1.7-3.3), respiratory morbidity (P<0.001; OR:3.64; 95% CI:1.7-7.4), neonatal depression (p<0.001; OR:2.94; 95% CI:1.00-8.62), any resuscitation/ventilation (P<0.05; OR: 3.1; 95% CI:1.15-8.31), probable sepsis (P<0.001; OR:11.2; 95% CI:2.5-49.8), confirmed sepsis (p=0.05; OR:7.7; 95% CI:0.9-63.9), or other problems like jaundice, hypoglycemia, hypothermia and feeding difficulty. The incidence of morbidity increased as gestational age decreases from 19.67% in term infants (>37 weeks) to 27.8%, 43%, 54.5% at 36, 35 and 34 weeks, respectively (P<0.001).Conclusions: The morbidity risk in late preterm births is 1.3 times more at 36 weeks, 2 times more at 35 weeks and 2.7 times more at 34 weeks as compared with term neonates. The mean cost of stay increased 1.8 times in the late preterm neonates as compared to the term neonates.

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A comparative study of morbidity pattern among term and late preterm infants in a tertiary care hospital

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20190693 ◽

2019 ◽

Vol 6 (2) ◽

pp. 593

Author(s):

Kiran Haridas ◽

Rajendra Shinde ◽

Pritesh Nagar ◽

Hemant Parakh

Keyword(s):

Birth Weight ◽

Preterm Infants ◽

Neonatal Period ◽

Tertiary Care ◽

Late Preterm ◽

Care Hospital ◽

Term Infants ◽

Late Preterm Infants ◽

Early Neonatal Period ◽

Increased Risk

Background: The incidence of preterm birth, defined as delivery before the end of the 37th week of pregnancy from the first day of the last menstrual period, is increasing. India accounts for the 40% of the global burden of low birth weight babies with 7.5million babies born with a birth weight of <2500g. The objective of the study is to compare the morbidity suffered by the late preterm infants with that of term infants.Methods: This was a retrospective study and the data for this study came from the medical records of maternal and neonatal case sheets and discharge summaries. The data was collected for the period between January 2014 and December 2014. All the late preterm infants born and admitted during early neonatal period were compared with term infants who were born and admitted during early neonatal period to the Aditya Hospital on the basis of maternal, infant and clinical characteristics.Results: A total 292 infants including LPTI and term infant records were obtained. LPTI group had significant problems compared to term infants. The predominant clinical problems at birth and during the early neonatal period are neonatal jaundice, transient tachypnea of newborn, feeding difficulty and probable sepsis.Conclusions: LPTI are at increased risk of morbidity compared to term infants and hence require special attention and care for possible complication during their early neonatal period.

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A prospective study comparing the morbidities of late preterm and term infants in the neonatal period in a tertiary care hospital

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20211666 ◽

2021 ◽

Vol 8 (5) ◽

pp. 803

Author(s):

Sirajuddin Nazeer ◽

Sivagurunathan Panchanathan ◽

Karthikeyan Soundararajan

Keyword(s):

Preterm Birth ◽

Prospective Study ◽

Preterm Infants ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Late Preterm ◽

Care Hospital ◽

Term Infants ◽

Late Preterm Infants ◽

Increased Risk

Background: In obstetric practice, 34 completed weeks is considered as maturational milestone for the fetus. Despite relatively large size and apparent functional maturity, late preterm infants are at increased risk for neonatal morbidity compared with full term infants. Aim of the study was to study the incidence of late preterm births in a tertiary care hospital in Trichy, Tamil Nadu and to study the pattern of neonatal morbidities in late preterm infants and to compare it with term infants.Methods: Hospital based prospective study was conducted from April 2019 to March 2020. Total 470 late preterm infants were included in our study. All infants enrolled in the study were followed up daily till discharge and after discharge, all infants were than reviewed at 15 and 28 days in a well-baby clinic.Results: There were a total of 1941 live births during the study period. Of these, 470 (24.2%) were late preterm and 1263 (65%) were term births. Late preterm infants accounted for 71.1% of preterm birth. Late preterm infants were at significantly higher risk for overall morbidity due to any cause, respiratory 22.1%, neonatal jaundice 62%, sepsis 4%, hypoglycemia 8.9%, hospital readmission 8.1%. 63% of late preterm infants were readmitted for jaundice.Conclusions: The incidence of late preterm birth was 24%. Late preterm infants had a higher incidence of jaundice, sepsis and respiratory morbidities. Late preterm infants had a longer hospital stay. They were also more likely to get readmitted in the hospital when compared to term infants.

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Morbidity and Mortality Profile of Late Preterm Neonates as Compared to Term Neonates from a Tertiary Care Centre in Silchar

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2021/458 ◽

2021 ◽

Vol 10 (30) ◽

pp. 2239-2243

Author(s):

Pranav N. Saji ◽

Anupama Deka

Keyword(s):

Preterm Infants ◽

Late Preterm ◽

Morbidity And Mortality ◽

Preterm Neonates ◽

Term Infants ◽

Term Neonates ◽

Maternal Risk ◽

Late Preterm Infants ◽

Increased Risk ◽

Preterm Babies

BACKGROUND Late preterm infants are less mature physiologically and have poor compensatory responses when compared to term infants. Recent studies have implied increased morbidities in late preterm infants and higher rate of hospital admission during neonatal period. Multiple maternal risk factors lead to the increasing incidence of late preterm births. We wanted to study the morbidity and mortality profile of late preterm infants compared to term infants. METHODS The study was conducted in the special newborn care unit (SCNU) of Silchar Medical College and Hospital. The study population comprised of 175 late preterm and 175 term babies admitted in SCNU. It was a cross sectional study. RESULTS In this study 175 late preterm neonates were compared with 175 term neonates. Late preterm babies were at increased risk of hypoglycemia (P value = 0.0130), neonatal jaundice (P = 0.021), culture positive sepsis (P = 0.001), respiratory distress (P = 0.000), hypocalcaemia (P = 0.030), difficulty in feeding (P = 0.000) and birth asphyxia (P = 0.013), longer hospital stay and mortality (P = 0.009) when compared to term babies. In babies of mothers with oligohydramnios and pregnancy induced hypertension, preterm babies had significant morbidity compared to term babies. CONCLUSIONS Late preterm babies have an increased risk of morbidity and mortality when compared to term neonates and need special care. Premature rupture of membranes, antepartum hemorrhage and pre-eclampsia are the main maternal complications leading to premature delivery of the baby. KEY WORDS Late Preterm, Preeclampsia, Oligohydramnios, Morbidity

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A RETROSPECTIVE ANALYSIS OF MATERNALAND FETAL OUTCOMES OF PRETERM DELIVERIES IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA.

10.36106/ijsr/0701516 ◽

2021 ◽

pp. 42-44

Author(s):

Varsha Konyala ◽

Poornima M ◽

Suma K.B

Keyword(s):

Preterm Delivery ◽

South India ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Preterm Births ◽

Late Preterm ◽

Preterm Neonates ◽

Care Hospital ◽

Maternal Complications ◽

Record Keeping

Aim:To study preterm delivery outcomes in a tertiary care hospital in South India. Methods: The study was conducted for a 7 month period from July 1, 2020 to January 31, 2021at JSS Hospital, Mysuru. Relevant details of every pregnant woman who underwent a preterm delivery and the subsequent neonate born were collected and followed till discharge. Results: The prevalence rate of preterm births was 11.81%. There were 44 early preterm deliveries and 88 late preterm deliveries. The most common maternal complications that lead to preterm births PPROM and preeclampsia.36 early preterm and 29 late preterm neonates required an NICU admission. This included 7 pairs of twins in the early preterm and 1 pair of twins in the late preterm. In the NICU, the most common complications noted were RDS, and sepsis.4 neonates remained by mother's side soon after delivery in the early preterm subset, whereas 54 of late preterm neonates were kept by the mother's side soon after delivery. 31 of 40 early preterm, 86 of the 88 of late preterm neonates were healthy and t for discharge. Conclusion:The prevalence of preterm birth rate in our study stands comparable to the reported global average. Preterm births have a multifactorial etiology. Timely referral to higher centers, experienced obstetricians, and a good NICU facility proved helpful to both the mother and neonate. Thorough record keeping also allows a true picture of preterm prevalence on the basis of which, policies and decisions can be made to further improve preterm care.

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"COMPARATIVE STUDY OF EARLY NEONATAL MORBIDITIES OF LATE PRETERM AND TERM NEONATES"

10.36106/8532772 ◽

2021 ◽

pp. 23-25

Author(s):

Jatin Manocha ◽

Kusum Mahajan ◽

Anuj Kumar

Keyword(s):

Preterm Infants ◽

Prospective Observational Study ◽

Neonatal Period ◽

Newborn Infants ◽

Late Preterm ◽

Preterm Neonates ◽

Feeding Problems ◽

Term Neonates ◽

Late Preterm Infants ◽

Study Results

Background- Newborn infants are unique in their physiology and the health problems that they experience. Neonatal period is dened from birth to under four weeks of age. Late preterm infants may physiologically and physically appear like infants born at term, but most late preterm infants may undergo complications like respiratory distress, apnea, hypothermia, feeding problems, hypoglycemia, hyperbilirubinemia, sepsis, and mortality. AIM-To compare the clinical prole of late preterm neonates with term neonates. MATERIALAND METHODS: This prospective observational study was carried out in neonatal division of department of pediatrics MMIMSR, Mullana. Eligible neonates delivered at MMIMSR, Mullana born from 34 weeks up to 42 weeks gestation were included. All infants enrolled in the study was followed daily till rst 7 days of life for any morbidity by clinical evaluation and review of hospital records.104 preterms included in the study and 226 term neonates were included in the study. Results- Preterms born via LSCS and NVD were(58%vs.42%).Morbidities in late preterms were Hypoglycemia (21.2% vs. 9.3%), Hypothermia (15.4%vs5.7%), hypocalcaemia (38.4% vs. 5.3%), neonatal hyperbilirubinemia(67.3% vs. 30.5%), feeding difculties(44.2% vs. 14.6%), sepsis(40.4% vs. 19.5%), respiratory support(53% vs. 47%)

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