scholarly journals Miller Fisher Syndrome: a case report

2017 ◽  
Vol 4 (4) ◽  
pp. 1193
Author(s):  
Shubhransu Patro ◽  
Vipin S. ◽  
Pankaj K. Khora ◽  
Payod K. Jena
Keyword(s):  
Case Report ◽  
Clinical Diagnosis ◽  
Clinical Features ◽  
Antibody Titer ◽  
Conservative Management ◽  
Recovery Phase ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Positive Serum ◽  
History Of

Miller Fisher Syndrome (MFS) is an uncommon variant of Guillain Barre syndrome (GBS). It is largely a clinical diagnosis based on the cardinal clinical features of ophthalmoplegia, ataxia and areflexia. The following case report is that of a patient who presented with an acute history of reeling of head, difficulty in opening the eyelids and swaying while walking, on clinical examination revealed the above-mentioned cardinal features and on investigation showed positive serum anti GQ1b antibody titer. The patient started recovering with conservative management and was discharged in the recovery phase.

scholarly journals Miller Fisher syndrome with early intracranial hypertension and delayed bilateral simultaneous facial nerve palsy: a case report

2019 ◽  
Vol 48 (3) ◽  
pp. 030006051986749
Author(s):  
Yu-Ming Liu ◽  
Yan-Li Chen ◽  
Yan-Hua Deng ◽  
Yan-Ling Liang ◽  
Wei Li ◽  
...  
Keyword(s):  
Case Report ◽  
Facial Nerve ◽  
Intracranial Hypertension ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Miller Fisher Syndrome ◽  
Ivig Treatment ◽  
Fisher Syndrome ◽  
Igm Antibodies ◽  
History Of

Miller Fisher syndrome (MFS), a variant of Guillain–Barré syndrome, is characterized by ataxia, areflexia and ophthalmoplegia. This case report describes a 40-year old male that presented with a 3-day history of unsteady walking and numbness on both hands, and a 2-day history of seeing double images and unclear articulation. Lumbar puncture revealed an opening pressure of 260 mm H2O. Plasma serology was positive for anti-ganglioside M1-immunoglobulin M (anti-GM1-IgM) antibodies and negative for anti-ganglioside Q1b (anti-GQ1b) antibodies. The patient was diagnosed with MFS based on the clinical course and neurophysiological findings. On the 4th day of treatment with intravenous immunoglobulin (IVIG), his ataxia and unsteady walking improved, but his bilateral eyeballs were fixed, and over the next few days he developed bilateral peripheral facial paralysis. After 5 days of IVIG treatment, methylprednisolone treatment was offered and the patient's symptoms gradually improved. Early intracranial hypertension and delayed facial nerve palsy may be atypical presentations of MFS. Anti-GM1-IgM antibodies may be the causative antibodies for MFS. If the IVIG therapy does not stop the progression of the disease, the addition of corticosteroid therapy may be effective. However, the relationship between IgM type, anti-GM1 antibody and MFS remains unclear and requires further research.

scholarly journals Miller Fisher variant of Guillain Barre Syndrome: A Case Report

2016 ◽  
Vol 10 (1) ◽  
pp. 44-45
Author(s):  
Radheshyam Saha ◽  
Suranjit Kumar Saha ◽  
Muhammad Nurul Islam ◽  
Mohammad Rafiqul Kabir ◽  
Aniruddha Mondal ◽  
...  
Keyword(s):  
Case Report ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Onset ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
History Of ◽  
Tendon Reflexes ◽  
Csf Examination

Miller Fisher Syndrome (MFS) is characterized by acute onset of ophthalmoplegia, ataxia and loss of tendon reflexes with relative sparing of strength in the extremities and trunk. Our patient Mr. Akter Sheikh, 40 years male, non diabetic, non hypertensive, presented with generalized weakness and difficulty in walking for 7 days preceded by a history of respiratory tract infection. After clinical and CSF examination, he was diagnosed as a case of Miller-Fisher syndrome. With treatment he improved significantly.Faridpur Med. Coll. J. Jan 2015;10(1): 44-45

scholarly journals Recurrent Miller Fisher syndrome: Case report

2021 ◽  
Author(s):  
A. Peral Quirós ◽  
F. Acebrón ◽  
M. del Carmen Blanco Valero ◽  
F. Labella Álvarez
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome

scholarly journals Acute Bilateral Ophthalmoparesis with Pupilary Areflexical Mydriasis in Miller-Fisher Syndrome Treated with Intravenous Immunoglobulin

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Theocharis Papanikolaou ◽  
Cath Gray ◽  
Bernard Boothman ◽  
Gerald Naylor ◽  
George Mariatos
Keyword(s):  
Intravenous Immunoglobulin ◽  
Nerve Palsy ◽  
Rare Condition ◽  
Miller Fisher Syndrome ◽  
Uneventful Recovery ◽  
Fisher Syndrome ◽  
History Of ◽  
Classical Triad ◽  
Fourth Nerve Palsy ◽  
Sixth Nerve

Miller-Fisher syndrome (MFS) is a rare condition characterized by the classical triad of ophthalmoplegia, ataxia, and areflexia (Fisher, 1956). It is considered a variant of Guillain-Barré syndrome (GBS) with which it may overlap, or it can occur in more limited forms. We report a case of a thirty-five-year-old male who presented with a six-day history of diplopia, following a recent chest infection. On examination, he was found to have bilateral sixth nerve palsy, bilateral fourth nerve palsy, bilateral areflexical mydriasis, ataxia and total absence of reflexes. After excluding other conditions, a diagnosis of Miller-Fisher syndrome was made. The patient was administered intravenous immunoglobulin and made an uneventful recovery.

scholarly journals Ocular Manifestations of Miller Fisher Syndrome: a Case Report

2021 ◽  
Vol 75 (3) ◽  
pp. 234
Author(s):  
Maja Ravlic ◽  
Lana Knezevic ◽  
Iva Krolo ◽  
Jelena Herman
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Ocular Manifestations

Headache and Ophthalmoparesis: Case Report of an “Atypical” Incomplete Miller-Fisher Syndrome

2018 ◽  
Vol 58 (5) ◽  
pp. 746-749
Author(s):  
David Moreno-Ajona ◽  
Pablo Irimia ◽  
Marta Fernández-Matarrubia
Keyword(s):  
Case Report ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome

scholarly journals Miller-Fisher Syndrome: Are Anti-GAD Antibodies Implicated in Its Pathophysiology?

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Ioannis E. Dagklis ◽  
Sotirios Papagiannopoulos ◽  
Varvara Theodoridou ◽  
Dimitrios Kazis ◽  
Ourania Argyropoulou ◽  
...  
Keyword(s):  
Clinical Features ◽  
Gamma Globulin ◽  
Miller Fisher Syndrome ◽  
Acid Decarboxylase ◽  
Gad Antibodies ◽  
Fisher Syndrome ◽  
Future Studies ◽  
Neurological Improvement ◽  
Intravenous Gamma Globulin

Miller-Fisher syndrome (MFS) is considered as a variant of the Guillain-Barre syndrome (GBS) and its characteristic clinical features are ophthalmoplegia, ataxia, and areflexia. Typically, it is associated with anti-GQ1b antibodies; however, a significant percentage (>10%) of these patients are seronegative. Here, we report a 67-year-old female patient who presented with the typical clinical features of MFS. Workup revealed antibodies against glutamic acid decarboxylase (GAD) in relatively high titers while GQ1b antibodies were negative. Neurological improvement was observed after intravenous gamma globulin and follow-up examinations showed a continuous clinical amelioration with simultaneous decline of anti-GAD levels which finally returned to normal values. This case indicates that anti-GAD antibodies may be associated with a broader clinical spectrum and future studies in GQ1b-seronegative patients could determine ultimately their clinical and pathogenetic significance in this syndrome.

Pleomorphic adenoma of the external auditory canal: a case report and review of the literature

1996 ◽  
Vol 110 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Hidetoshi Haraguchi ◽  
Hitoshi Hentona ◽  
Hidekazu Tanaka ◽  
Atsushi Komatuzaki
Keyword(s):  
Case Report ◽  
Natural History ◽  
Pleomorphic Adenoma ◽  
Clinical Features ◽  
External Auditory Canal ◽  
World Wide ◽  
Review Of The Literature ◽  
The World ◽  
History Of ◽  
Uncommon Tumour

AbstractPleomorphic adenoma arising in the external auditory canal is rare. We report the case of a 38-year-old man. To better grasp the clinical features and natural history of this uncommon tumour, we also reviewed the world wide literature and found 24 similar cases, which we analysed together with our own.

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