scholarly journals Fungal nasopharyngitis masquerading as nasopharyngeal mass in an immunocompetent patient: a case report

Author(s):  
P. Karthikeyan ◽  
Nikhil Sivanand ◽  
Neelima Vijayan ◽  
Vishnu Kumar ◽  
Nanditha Srinivasa ◽  
...  

<p><span>Isolated nasopharyngeal candidiasis in an immunocompetent host, has not been reported in literature. This is a case of a 48 year old lady with no comorbidities who presented with a mass in the nasopharynx mimicking nasopharyngeal malignancy. Endoscopic debridement and biopsy revealed necrotic tissue with fungal ball composed of filamentous hyphae suggestive of aspergillus and budding yeast form of Candida. A diagnosis of fungal nasopharyngitis was made and started on antifungal therapy for 6 weeks following which patient is relieved of symptoms.</span></p>

2014 ◽  
Vol 7 (2) ◽  
pp. 64-66
Author(s):  
Amanjit Bal ◽  
Bhumika Gupta ◽  
Rijuneeta Gupta

ABSTRACT Invasive mycotic infections can be effectively treated if rapid identification of fungus is obtained. We reported a case of coinfection by Aspergillus and Rhizopus sp. involving nose, paranasal sinuses and orbit in a 51 years old male patient diagnosed as diabetic on admission. He presented to ENT OPD with history of drooping of right upper eyelid, decreased vision right eye and deviation of angle of mouth to left side for 12 days. NCCT nose, PNS and orbit showed soft tissue density in right maxillary sinus, ethmoids and destruction of right inferior turbinate. MRI of nose, PNS and orbit revealed hypointense density in right maxillary and ethmoid sinuses on T1-weighted images and on T2-weighted; it was hyperintense. Patient underwent endoscopic debridement under general anesthesia and tissue was sent for microbiological and histopathological examination which confirmed presence of Aspergillus and Rhizopus. Patient responded to therapy with IV amphotericin B and surgical debridement. On discharge patient's condition was good. How to cite this article Gupta R, Gupta B, Bal A, Gupta AK. Sinonasal Mucormycosis with Fungal Ball: A Rare Case Report. Clin Rhinol An Int J 2014;7(2):64-66.


2019 ◽  
Vol 6 (2) ◽  
pp. 50-54
Author(s):  
Sergio Moya ◽  
Mily Yañez ◽  
Cristóbal Palma

Introduction: Aspergillosis is the second most frequent opportunistic fungal infection of the paranasal sinuses. It primarily affects the maxillary sinus and occurs mainly in immunocompromised individuals. Infection is caused by inhalation of spores or by an oro-sinusal communication. Aspergillosis is classified into an invasive and non-invasive form or Aspergilloma, which usually affects immunocompetent patients. Violaceous lesions, ulcers, necrosis and tissue destruction can be manifested clinically. Patients may experience pain, paresthesias, increases in the volume of purulent or bloody nasal discharge and congestion. Case report: A 62-year-old female patient, immunocompetent, with a condition evolving for about six years. Condition began after a dental extraction, and consisted of absence of scarring and recurrent episodes of symptomatology suggestive of maxillary sinusitis with poor response to antibiotics. The patient was referred to the maxillofacial care unit, presenting an increase of volume in the right genial region, pain and paraesthesia of infraorbital region. The CT scan showed the presence of a radiopaque foreign body in the right maxillary sinus. A surgical procedure was carried out using the Caldwell-Luc technique and biopsy; the case was diagnosed with Aspergillosis. The patient was treated without antifungal therapy because she had a good immune status. Conclusion: Aspergilloma is the most common form of Aspergillosis in immunocompetent individuals. It is usually diagnosed late, as its clinical picture is similar to bacterial sinusitis. In most cases, patients respond well to surgical treatment, and systemic antifungal therapy is not necessary.


2019 ◽  
Vol 2019 (8) ◽  
Author(s):  
Geng Ju Tuang ◽  
Farah Dayana Zahedi ◽  
Izzah Akashah ◽  
Jennifer Peak Hui Lee ◽  
Zainal Azmi Zainal Abidin

Abstract The clinical presentation of a sphenoid fungal ball (FB) is often non-specific and tends to be overlooked, particularly in hosts with an intact immune status. Rarely, potentially life-threatening complications may arise, owning its anatomical characteristics with contiguous structures. Herein, we present an unusual case of sphenoid FB complicated with orbital apex syndrome in an immunocompetent patient. The diagnosis dilemma and subsequent management are further discussed.


2021 ◽  
Vol 156 (8) ◽  
pp. 411-412
Author(s):  
Diana Esteller ◽  
Laura Llansó ◽  
Ona Escoda

Author(s):  
Esfandiar Shojaei ◽  
Joanna C Walsh ◽  
Nikhil Sangle ◽  
Brian Yan ◽  
Michael S Silverman ◽  
...  

Abstract Disseminated histoplasmosis is a life-threatening disease usually seen in immunocompromised patients living in endemic areas. We present an apparently immunocompetent patient with gastrointestinal histoplasmosis who was initially diagnosed as biopsy-proven Crohn’s disease. Following discontinuation of anti-inflammatory drugs and institution of antifungal therapy, his GI illness completely improved. Specific fungal staining should be routinely included in histopathologic assessment of tissue specimens diagnosed as Crohn’s disease.


2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
P. Lucas Ramirez ◽  
Kelly Barnhill ◽  
Alan Gutierrez ◽  
Claire Schutte ◽  
Laura Hewitson

This case report describes the benefits of antibiotic and antifungal therapy on behavior in a child with autism undergoing treatment for encopresis. Over the course of treatment, the child exhibited a reduction in aberrant behaviors, increased gastrointestinal function, and improved quality of life.


2010 ◽  
Vol 52 (2) ◽  
pp. 107-110 ◽  
Author(s):  
Juan Nunura ◽  
Tania Vásquez ◽  
Sergio Endo ◽  
Daniela Salazar ◽  
Alejandrina Rodriguez ◽  
...  

We report a case of severe toxoplasmosis in an immunocompetent patient, characterized by pneumonia, retinochoroiditis, hepatitis and myositis. Diagnosis was confirmed by serology, T. gondii in thick blood smear and presence of bradyzoites in muscle biopsy. Treatment with pyrimethamine plus sulfadoxine was successful but visual acuity and hip extension were partially recovered. This is the first case report of severe toxoplasmosis in an immunocompetent patient from Peru.


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