scholarly journals A rare case of a solitary laryngeal xanthoma and its clinical implications in a developing country like India

Author(s):  
Bharathi Murundi Basavarajaiah ◽  
Kumar Shankar De ◽  
Rakesh Bambore Suryanarayan Rao ◽  
Babu Ambale Rudrappa

<p class="abstract">We present a rare case of a solitary laryngeal xanthoma in a 42 year old male, with complaints of hoarseness and change in voice since1 year. Direct laryngoscopic examination revealed a smooth textured polyp like mass arising from anterior 1/3rd of left vocal cord. No other similar lesions were noted anywhere else on his body. Microlaryngeal excision of mass was done and sent for histopathological examination, which showed fragments of stratified squamous epithelium with sub-epithelium displaying sheets of foamy cells. Immunohistochemistry was positive for CD68 and a diagnosis of solitary laryngeal xanthoma was arrived at. Follow up of the patient showed no recurrence but investigations revealed dyslipidemia, which was newly detected. Hence a diagnosis of a solitary laryngeal xanthoma, even without any other lesions, warrants a thorough investigative workup, including lipid profile, even in patients who are not known cases of dyslipidemia. This becomes especially important in a country like India, where a large number of cases of dyslipidemia go undetected; leading to atherosclerosis and even cardiac events in the future.</p>

Author(s):  
Firamir Bin Zulkifli ◽  
Farah Dayana Bintin Zahedi ◽  
Ahmad Bin Nordin ◽  
Yong Doh Jeing

<p>Pilonidal sinus is widely associated with disease involving the gluteal cleft. Derived from the Latin word (Pilus=hair; nidus=nest), it was first described by Herbert Mayo in 1833. The pathognomonic finding of the pilonidal sinus is the presence of loose hairs in the sinus tract or cavity. We report a case of a fit middle age policeman who developed an unusual chronic discharging sinus over the tip of the nose. A computed tomography (CT) sinogram showed a localized blind subcutaneous tract over the nose. The course of management is discussed with reference to other reported works of literature. The patient was diagnosed to have a subcutaneous sinus over the tip of the nose with the aid of CT sinogram. Surgery was performed to excised the sinus tract through external rhinoplasty approached. Histopathological examination confirmed a sinus tract lined by keratinized stratified squamous epithelium with a tuft of hair. Patient was follow up for another year with no evidence of recurrence.</p>


Author(s):  
Rakesh Srivastava ◽  
Vini Tandon

<p class="abstract">Teratomas are embryonal neoplasm arises from totipotent germ cells. They are having tissues from all the three blastodermic layers. There are various locations of congenital teratoma. Naso-oropharyngeal site teratoma are either sessile or pedunculated. We describe a rare case of laryngeal teratoma in a five years old patient presented with change in voice and breathing difficulty. On flexible laryngoscopy, it appeared like supraglottic cyst but on CT scan it was confirmed as teratoma. Pre-operative tracheostomy and transoral carbon dioxide laser assisted excision done. Histopathological examination showed osteoid trabeculae, chondroid tissue with loose myxoid islands and adipose tissue. No recurrence of tumor on 18 months follow-up. This is the first case report of pediatric larynx teratoma reported in present century.</p>


2012 ◽  
Vol 02 (01) ◽  
pp. 51-53
Author(s):  
Harish S. Permi ◽  
Pretty D'Souza ◽  
K.R. Bhagavan ◽  
Mary Raju ◽  
Pooja Sarda

AbstractPrimary Dirofilariasis is caused by a Zoonotic filarial nematode. It is transmitted to humans by Culex, Aedes, or Anopheles mosquitoes, which ingest blood-containing microfilaria from affected dogs, cats, or raccoons. Chest wall tumors are uncommon lesions that originate from blood vessels, nerves, bone, cartilage, or fat. We report a case of Human Dirofilariasis due to D. Repens occurring in the chest wall in a 32 year old male. Clinical diagnosis of benign chest wall tumor was considered and it was excised. Histopathological examination confirmed it as Dirofilaria repens. On regular follow up he is doing fine.


2015 ◽  
Vol 87 (9) ◽  
Author(s):  
Radhika Vidyasagar ◽  
Sudarshan ◽  
Sreedhar ◽  
Subramanya ◽  
Vidya Bhat

AbstractMesenteric fibromatosis is a part of the clinical-pathologic spectrum of deep fibromatoses. We report this rare case of primary mesenteric tumor that was diagnosed to be a mesenteric fibromatosis on histopathological examination.In majority of patients it may remain asymptomatic and the management of these tumors depends on histopathological examination. Postoperatively, patient was well and subsequent follow up showed normal recovery.


2012 ◽  
Vol 02 (02) ◽  
pp. 57-59
Author(s):  
Harish S. Permi ◽  
Rohan Shetty ◽  
Shalmali Alva ◽  
Balakrishna Shetty ◽  
Rajesh Ballal ◽  
...  

AbstractScrotal calcinosis is a benign disease characterized by multiple calcified scrotal nodules. The nodules develop slowly over many years and patients usually do not seek for treatment, until they grow to large size. Histopathological examination shows deposition of basophilic amorphous material surrounded by giant cell granulomatous reaction. We report two cases of scrotal calcinosis occurring in 27 year and 45 year old males who presented with multiple scrotal swellings. Clinical diagnosis was multiple sebaceous cysts. On histopathology, excised swellings showed deposition of calcium with giant cell reaction. On regular follow up both are doing fine without any recurrence.


Author(s):  
Pranav Gupta ◽  
Etti Goyal ◽  
A Dokania ◽  
Y Rizvi

ABSTRACT Papilloma is a histopathological term describing tumors of a classical finger-like or cauliflower morphology. Though benign, they carry profound malignancy potential and can present at numerous anatomical locations, such as skin, cervix, esophagus, respiratory tract, breast duct, etc. Papillomas over conjunctiva are not frequently encountered and carry special significance. A 60-year-old diabetic female presented with a left upper lid marginal sessile mass of 9 months duration with mild epiphora and foreign body sensation. On examination, a solitary, fleshy, sessile, polypoidal mass measuring 1 × 1 cm was seen, with irregular cauliflower-like surface present over lateral aspect of left upper lid, firm in consistency with raised edges. Visual acuity in right eye was 6/18→6/9 and left eye 6/36→6/9, intraocular pressure (IOP) was 14.6 mm Hg in both eyes by Schiotz tonometry. Complete excision of the lesion employing microsurgical technique with close apposition of lid margin using 6-0 Vicryl sutures was done under local anesthesia (LA). Histopathological examination revealed stratified squamous epithelium forming papillae with variable goblet cells supported by prominent branching fibrovascular cores in the center. A satisfactory cosmetic result was achieved. Follow-up of 6 months did not reveal any recurrence. A satisfactory functional and cosmetic result achieved. Squamous papillomas over lid margin are uncommon presentations. Even though benign they carry morbidity potential in the form of chronic epiphora, corneal erosions, and lid deformities if inadequately managed. How to cite this article Goyal E, Gupta P, Dokania A, Rizvi Y. Squamous Papilloma over Lid Margin: An Uncommon Presentation. Int J Adv Integ Med Sci 2016;1(3):128-130.


1975 ◽  
Vol 84 (3) ◽  
pp. 308-314 ◽  
Author(s):  
John Compagno ◽  
Vincent J. Hyams ◽  
Pierre Ste-Marie

The clinical, microscopic, and gross features of 36 cases of benign granular cell tumor arising in the larynx are reviewed and studied. This infrequent lesion, when in the larynx, is found most commonly on the true vocal cord in adults in their third, fourth, and fifth decades; there is no obvious sex predilection. Slowly increasing hoarseness was the primary complaint in our cases. Clinically, the tumors are considered benign. The most common clinical impression was a vocal cord papilloma. The microscopic pattern of the granular cell tumors is uniform and bland, but there may be a marked pseudoepitheliomatous hyperplasia of the overlying squamous epithelium, often stimulating squamous cell carcinoma. Follow-up information is discussed, as is the origin and histogenesis of this lesion.


2019 ◽  
Vol 6 (12) ◽  
pp. 4654-4656
Author(s):  
Yücel Kılıçkap ◽  
Mehmet Aktaş ◽  
Lezgin Kıran ◽  
Abdullah Gedik ◽  
M.Kamuran Bircan

Renal cell carcinoma (RCC), is the most common kidney cancer, that accounts for approximately  90% of all adult renal malignancies with 30% of patients presenting with metastasis at initial diagnosis.There are several reports of metastases developing after 10-20 years even if curative nephrectomy has been made. Clear cell (60%-75%), papillary (10%-15%), chromophobe (5%), and collecting duct carcinoma are well characterized subtypes of RCC.Renal cell carcinoma mainly metastasizes to the lungs,the bones,the liver,the lymph nodes and brain.Metastasis to the head and neck region is rare.In this case report we present a tonsil metastasis after 5 years of nephrectomy.Surgery with histopathological examination confirmed that metastasis of clear cell carcinom.The patient was successfully treated by surgery and referred to oncology.Later he was out of our follow-up.


2019 ◽  
Vol 11 (2) ◽  
pp. 181-188
Author(s):  
Eliya Shrestha ◽  
Laxman Banstola ◽  
Indra Man Maharjan ◽  
Babita Gurung ◽  
Harimaya Gurung ◽  
...  

Purpose: This study has attempted to assess the profile and treatment outcome of patients with OSSN and report the recurrence rate following treatment of primary OSSN. Materials and Methods: This was a retrospective, non-comparative hospital based observational study. The case files of OSSN patients from Jan 2010 to Dec 2017were assessed. The study site was Himalaya Eye Hospital, Gharipatan, Pokhara. This hospital is the only eye hospital in province 4, Nepal. All the files of suspicious cases of conjunctival mass or OSSN were reviewed. Data regarding demographic characteristics, vision acuity, involved eye, clinical features, conjunctival lesion type, duration of symptoms, preoperative clinical diagnosis, history, other eye disease, associated systemic diseases, occupation as well as treatment modalities of the patients and its outcome were taken. Results: Out of 40 cases, females were 21(52.5%) vesus 19(47.5%) male. Amongthem, 19 patients had keratinized stratified squamous epithelium, 17 had conjunctiva intraepithelial squamous neoplasia and 4 had invasive squalors cell carcinoma. Predominance age group was 15-59 age (25/40, 62.5%), among which 12 had keratinized stratified squamous epithelium, 11 conjunctival intraepithelial squamousneoplasia and 2 had invasive squamous cell carcinoma conjunctival lesion. The mean duration of symptoms was about nine months (S.D. = 5.972). The mean size of lesion mass was 3.28 mm (SD=1.569). More than half of the cases (55%, 22/40) had the mass located at nasal limbus. 95% (38/40) cases underwent lesion total excision and direct closure and 5% (2/40) underwent lesion excision followed by Amniotic Membrane grafting. Only 5% (2/40) cases, those who had undergone lesion excision, the lesion recurrence was observed during follow up period of 31 months. Conclusion: The outcome of the OSSN following the treatment was found to be satisfactory. Further studies with prolonged follow-up are recommended to evaluate the risk of recurrence and other adverse effects.


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