scholarly journals Image guided biopsy/FNAC in head and neck cancers in covid 19 pandemic

Author(s):  
Rajesh A Kantharia ◽  
Roopa Ganta ◽  
Shehnaz R Kantharia ◽  
Bhavin Bhupendra Shah

Suspected growth in the region of base of tongue, pharynx, and larynx need direct/indirect laryngoscopy for establishing Diagnosis and for Staging of the disease. The Covid 19 Pandemic has severely affected these modes of examination because they are Aerosol Generating Procedures and carry very high risk of transmission of the Virus. The Department of Head And Neck Oncosurgery at KCHRC is one of the busiest department at our Institute with an average annual footfall of around 20,000 new patients. The main objective of our study is to know the role of Image Guided Biopsy/FNAC for primary diagnosis in Head and Neck Cancers. Retrospective analysis of prospectively collected data of 35 patients was done from April to September 2020. Histopathological records along with patient’s clinical records were reviewed. Of the 35 patients, 23 patients underwent CT Guided biopsies, 11 patients had CT Guided FNA and one patient had USG guided biopsy. In 23 patients (CT Guided Biopsy), the biopsy was taken from tongue in 16 patients, Larynx in two patient, Pyriform sinus(PFS), posterior pharyngeal wall, RMT (retromolar trigone), lower GBS and Tonsil sites had one patient each. Of the 11 CT Guided FNAC patients, the site of FNA was from PFS in 7 patients, Tongue in 2 patients RMT and soft palate had one patient each. One patient had undergone USG Guided biopsy for PFS lesion. Out of 35 patients, tissue specimen taken was adequate in 33 patients and inadequate in two patients. The results were supported both histologically and clinically. The histological confirmation was found in 88.6% cases (31/35), squamous cell carcinoma was found in 74.3% cases (26/35), no malignancy in 8.5% cases(3/35), no specific lesion in 5.7% cases(2/35), no definitive diagnosis in 2.8% cases(1/35) and in inadequate in 8.5% cases(3/35). Repeat biopsy in one patient revealed no malignancy. There were no post procedure complications noted. Image guided biopsy/FNAC is a safe, reliable minimally invasive technique and can be used for primary diagnosis of Head and Neck cancers without the risk of Aerosol generation in the current Covid -19 Pandemic.

2014 ◽  
Author(s):  
Charles W. Spangler ◽  
Jean R. Starkey ◽  
Bo Liang ◽  
Sara Fedorka ◽  
Hao Yang ◽  
...  

2004 ◽  
Vol 130 (6) ◽  
pp. 690-697 ◽  
Author(s):  
Samuel Ryu ◽  
Mumtaz Khan ◽  
Fang-Fang Yin ◽  
Adrianne Concus ◽  
Munther Ajlouni ◽  
...  

2000 ◽  
Vol 110 (3) ◽  
pp. 382-385 ◽  
Author(s):  
Elmar M. Merkle ◽  
Jonathan S. Lewin ◽  
Andrik J. Aschoff ◽  
David W. Stepnick ◽  
Jeffrey L. Duerk ◽  
...  

2013 ◽  
Vol 7 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Dario Pasalic ◽  
Patrick H. Luetmer ◽  
Christopher H. Hunt ◽  
Peter S. Rose ◽  
Felix E. Diehn ◽  
...  

We report a case of a benign notochordal cell tumor (BNCT) of the sacrum with atypical imaging features, which was incidentally discovered in a 74-year-old man undergoing evaluation for progressively worsening hip and back pain. It is important for radiologists, pathologists and orthopedic surgeons to be aware of the diagnosis of BNCT and be familiar with its radiographic features to avoid unnecessary treatment. This case illustrates the advantage of percutaneous computed tomography (CT)-guided biopsy as a minimally invasive technique for definitive diagnosis of a BNCT with atypical imaging features.


2021 ◽  
Vol 10 ◽  
Author(s):  
Liang Zhao ◽  
Peiqiong Chen ◽  
Kaili Fu ◽  
Jinluan Li ◽  
Yaqing Dai ◽  
...  

ObjectiveProgrammed death-ligand 1 (PD-L1) expression status is a crucial index for identifying patients who will benefit from anti-programmed cell death protein 1 (PD-1)/PD-L1 therapy for non-small cell lung cancer (NSCLC). However, the concordance of Tumor Proportion Score (TPS) between biopsies and matched surgical specimens remains controversial. This study aims to evaluate the concordance of PD-L1 expression between image-guided percutaneous biopsies and matched surgical specimens.MethodWe evaluated 157 patients diagnosed with operable NSCLC on both surgical tissue sections and matched lung biopsies retrospectively. The patients underwent either regular computed tomography (CT)-guided biopsy (n = 82) or positron emission tomography (PET)/CT-guided biopsy (n = 75). The concordance between surgical specimens and lung biopsies for PD-L1 TPS was evaluated using Cohen’s kappa (κ) coefficient.ResultsImmunohistochemical expression of PD-L1 was evaluated in both surgical resected specimens and matched biopsies in the eligible 138 patients. The concordance rate of PD-L1 expression between surgical tissue sections and matched biopsies was fairly high at 84.1% (116/138), and the κ value was 0.73 (95% CI: 0.63–0.83, P < 0.001). The concordance rate was higher for tissue sections from PET/CT-guided biopsy than for tissue sections from CT-guided biopsy [88.6% (62/70, κ value: 0.81) vs 79.4% (54/68, κ value: 0.66)].ConclusionPD-L1 TPS was strongly concordant between surgical specimens and matched lung biopsies. Thus, the routine evaluation of PD-L1 expression in diagnostic percutaneous biopsies could be reliable for identifying patients who will benefit from anti-PD-1/PD-L1 immunotherapy.


1994 ◽  
Vol 73 (1) ◽  
pp. 41-43 ◽  
Author(s):  
Nicholas J. Daniello ◽  
Steven I. Goldstein

Retropharyngeal hematomas are relatively rare. They are clinically important because of the close proximity of the retropharyngeal space to the upper airway. Any swelling in the space may cause the posterior pharyngeal wall to bulge anteriorly into the airway and cause airway obstruction. Management starts with securing and maintaining the patient's airway. Diagnosis rests upon clinical examination and radiographic studies. Treatment depends upon the size of the hematoma as well as the clinical course of the patient. Smaller hematomas may be observed. Larger hematomas and those that fail to reabsorb should undergo drainage. A case of retropharyngeal hematoma following minor blunt head and neck trauma is presented. We review the literature and present management and treatment principles for this group of patients.


2010 ◽  
Vol 76 (3) ◽  
pp. 767-774 ◽  
Author(s):  
Omar A. Zeidan ◽  
Adam J. Huddleston ◽  
Choonik Lee ◽  
Katja M. Langen ◽  
Patrick A. Kupelian ◽  
...  

Oral Oncology ◽  
2011 ◽  
Vol 47 (9) ◽  
pp. 900-904 ◽  
Author(s):  
Nam P. Nguyen ◽  
Dave Abraham ◽  
Anand Desai ◽  
Michael Betz ◽  
Rick Davis ◽  
...  

2005 ◽  
Vol 84 (6) ◽  
pp. 362-365 ◽  
Author(s):  
Himani Lade ◽  
Neelima Gupta ◽  
P.P. Singh ◽  
Geeta Dev

Spindle-cell hemangioendothelioma is an uncommon vascular lesion that exhibits a predilection for the extremities. Very few reports have been published describing this lesion in the head and neck, and to the best of our knowledge, its occurrence in the oropharynx has not been previously reported. In addition to reporting an unusual site of this lesion, our rationale for publishing this case is to comment on the diagnostic dilemma that arose in view of an unclear clinicohistopathologic pattern and to discuss this lesion's similarity to other aggressive tumors.


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