Comparative study of efficacy and safety of fractional CO2 laser and microneedling fractional radiofrequency (MnRF) in the treatment of striae distensae

Abstract Background Acne scarring is often the primary concern of a patient with acne. Acne scarring can cause depression and is a risk factor for suicide. Patients feel their appearance interferes with their relationships and chances of future employment. Acne scars can be classified into 3 different types: atrophic, hypertrophic, or keloidal. Atrophic acne scars are the most common type. Atrophic acne scars are divided into three main types: ice pick, rolling and boxcar scars. Aim of the Work To compare the results of whole facial area versus Focal Acne Scar Treatment (FAST) by factional CO2 laser in a split face study. Patients and Methods The present study is a split face comparative study which included 20 adult patients with atrophic acne scars ranged from 18 to 44 years old of both sex. The study was approved by the Research Ethical Committee, Faculty of Medicine, Ain Shams University and fulfilled all the ethical aspects required in human research. All patients received full information about description of the procedure of treatment, possible side effects, photo documentation and they all provided written consent. Results Patients were asked to compare the pain, peeling and complications between the right and left sides post CO2 fractional treatment: pain was more at right side in 35% of cases and more at left side in 30% of cases and equal in the rest of cases, peeling was faster at the right side in 60% of cases, faster at the left side in 20% of cases and equal at the rest of cases, 4 of the patients had post inflammatory hyperpigmentation (1 patient at right side, 2 patients at left side and 1 patient at both sides), no other complications were recorded as secondary infection, scaring keloid and prolonged erythema. Conclusion We compared the results of whole facial area treatment in the right side of the face versus Focal Acne Scar Treatment (FAST) in the left side by factional CO2 laser. We discovered that there is a statistically highly significant relationship between the improvement of acne scars and treatment with fractional CO2 laser by the either techniques. Both techniques are preferable in treating acne scars in equal degree.

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Comparative study of fractional CO2 laser and fractional CO2 laser-assisted drug delivery of topical steroid and topical vitamin C in macular amyloidosis

Lasers in Medical Science ◽

10.1007/s10103-018-2457-1 ◽

2018 ◽

Vol 33 (4) ◽

pp. 909-916 ◽

Cited By ~ 8

Author(s):

Rehab Mohamed Sobhi ◽

Iman Sharaoui ◽

Eman Ahmad El Nabarawy ◽

Reham Shehab El Nemr Esmail ◽

Rehab Aly Hegazy ◽

...

Keyword(s):

Drug Delivery ◽

Vitamin C ◽

Comparative Study ◽

Co2 Laser ◽

Topical Steroid ◽

Fractional Co2 Laser ◽

Macular Amyloidosis

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A comparative study on the efficacy of fractional CO2 laser and fractional CO2 laser with autologous platelet-rich plasma in scars

Indian Dermatology Online Journal ◽

10.4103/idoj.idoj_174_20 ◽

2020 ◽

Vol 11 (6) ◽

pp. 930

Author(s):

Sandeep Arora ◽

Satish Godara ◽

Rajeshwari Dabas ◽

Gulhima Arora ◽

Gopi Renganathan ◽

...

Keyword(s):

Comparative Study ◽

Co2 Laser ◽

Platelet Rich Plasma ◽

Fractional Co2 Laser ◽

Autologous Platelet Rich Plasma ◽

Autologous Platelet

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Efficacy of Fractional Co2 Laser and Human Lyophilized Growth Factors in the Treatment of Stretch Marks: A Clinical and Histopathological Study

QJM ◽

10.1093/qjmed/hcab093.043 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Mahmoud Abdel Reheem Abdallah ◽

Azza Esmat Mostafa ◽

Shawkat Mohammad Abdel Hameed Mohammad

Keyword(s):

Growth Factors ◽

Co2 Laser ◽

Punch Biopsy ◽

Skin Condition ◽

Histopathological Study ◽

Natural Evolution ◽

Striae Distensae ◽

Medical Problems ◽

Fractional Co2 Laser ◽

Common Skin

Abstract Background Striae distensae are a well-recognized, common skin condition that rarely causes any significant medical problems but are often a significant source of distress to those affected. The natural evolution of striae is from red or purple, raised wavy lesions (striae rubra) to white atrophic lesions with wrinkly surface (striae alba). Objectives The present study was designed to compare the efficacy of fractional CO2 laser alone or combined with lyophilized growth factors or to its efficacy alone in the treatment of striae distensae. Patients and Methods The present study included 20 female patients with SD; they were all recruited from Dermatology Outpatient Clinic, Ain Shams University from may 2017 to march 2018. An informed consent for treatment, photography and punch biopsy was taken before enrollment and the study was approved by Dermatology Research Ethical Committee. Results The present study showed statistically significant clinical and histopathological improvement in areas A and B after treatment. This impronment was in rubra more than alba. Area C showed no clinical and histopathological improvement. Area B showed better results than area A.We propose that LGF alone did not show clinical or histopathologiacl improvement. Treatment was tolerated well by all patients where side effects were minimal in the form of transient PIH that resolved after using bleaching creams. There was no statistically sgnificant difference in the incidence of PIH between areas A& B. Conclusion We concluded that fractional CO2 alone is effective in treatment of SD especially stria rubra in skin type III and IV.

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Response to the letter to the editor: Efficacy and safety of ablative fractional CO2 laser for the treatment of burn scars: A case-control study

Burns ◽

10.1016/j.burns.2021.08.003 ◽

2021 ◽

Author(s):

Andrea C. Issler-Fisher ◽

Oliver M. Fisher ◽

Peter A. Haertsch ◽

Zhe Li ◽

Peter K.M. Maitz

Keyword(s):

Co2 Laser ◽

Case Control Study ◽

Case Control ◽

Efficacy And Safety ◽

Fractional Co2 Laser ◽

Letter To The Editor ◽

Control Study

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A comparative study of efficacy of dermaroller versus fractional CO2 laser for management of post acne scars

International Journal of Dermatology, Venereology and Leprosy Sciences ◽

10.33545/26649411.2021.v4.i1b.72 ◽

2021 ◽

Vol 4 (1) ◽

pp. 83-87

Author(s):

BM Monisha ◽

Kannan Gopalan ◽

Dr. TV Ramana Rao

Keyword(s):

Comparative Study ◽

Co2 Laser ◽

Fractional Co2 Laser ◽

Acne Scars

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THE EFFICACY OF FRACTIONAL CO2 LASER WHEN COMBINED WITH PLATELET-RICH FIBRIN MEMBRANE FOR FACIAL REJUVENATION

10.36106/ijsr/2535923 ◽

2021 ◽

pp. 1-3

Author(s):

Vasim F Chauhan ◽

Krina B Patel ◽

Nitin S Vora

Keyword(s):

Co2 Laser ◽

Topical Application ◽

Autologous Blood ◽

Facial Rejuvenation ◽

Efficacy And Safety ◽

Platelet Rich Fibrin ◽

Fractional Co2 Laser ◽

Combined Use ◽

Aesthetic Procedures ◽

Fibrin Membrane

Background: Facial rejuvenation is different from other aesthetic procedures in that it directly restores a younger appearance in patients. Demand for a youthful and attractive appearance has increased recently and mass media have promoted the desire for beauty. Fractional-CO2 laser one of the most utilised modality for this purpose nowadays but there are few drawbacks of this method which can be reduced and efficacy can be increased by the addition of autologous blood components. Objectives: We evaluated the synergistic efficacy and safety of combined use of fractional-CO2 laser and topical application platelet-rich fibrin membrane for facial rejuvenation. Methodology: Total of 12 patients (M:5, F:7) was included in the study. All patients were treated once with fractional-CO2 laser followed by topical application of platelet-rich fibrin membrane application over face for 30 minutes. Patients were evaluated at baseline, one, four, and eight weeks after the session. Result: PRF when applied after fractional-CO2 laser showed additive effects on facial rejuvenation with lesser downtime.

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