scholarly journals Microbiological profile and their antibiotic sensitivity pattern in patients of chronic suppurative otitis media at eastern tertiary care center of Nepal

2020 ◽  
Vol 3 (3) ◽  
pp. 86-90
Author(s):  
Bajarang Prasad Sah ◽  
◽  
Shyam Thapa Chettri ◽  
Narayan Raj Bhattarai ◽  
Shankar Prasad Shah ◽  
...  
Author(s):  
Raj Tajamul Hussain ◽  
Sanam Altaf ◽  
Owais Makhdoomi ◽  
Mariya Ali

<p class="abstract"><strong>Background:</strong> The aim of the study was to discern the patterns in microbial diversity and the resistogram among the patients suffering from CSOM.</p><p class="abstract"><strong>Methods:</strong> A total number of 100 ear swabs were investigated for the present study. Their gram staining, direct microscopy with KOH, culture sensitivity, and biochemical tests were carried out to identify the organisms and to know their sensitivity pattern. All the swabs were collected from clinically diagnosed cases of chronic suppurative otitis media visiting otolaryngology outpatient department of tertiary care hospital. The study period was one year, from January 2016 to December 2017.  </p><p class="abstract"><strong>Results:</strong> Out of total 100 cases, 90 were culture<strong> </strong>positives, 6 showed no growth and 4 were<strong> </strong>skin contaminants (mirococci). Out of 90 culture positives, fungal culture was positive in 5 (5.5%) while combined bacteria and fungi obtained in 18 (20%) cases and only bacteria in 67 (74.4%) cases. Among the aerobic bacterial isolates, Pseudomonas aeruginosa was the most common bacteria isolated from the bacterial culture (n=36; 34.95%) followed by <em>Staphylococcus aureus </em>(n=28; 27.18%) and <em>Proteus</em> (n=13; 12.62%). Among the fungal isolates,<strong> </strong><em>Aspergillus niger </em>was predominant followed<strong> </strong>by Candida <em>albicans </em>&amp; <em>Aspergillus flavus.</em> Amikacin and imipenem were found to be the most effective antibiotics with low resistance rates.</p><p><strong>Conclusions:</strong> The present study gave an insight into the bacteriological profile of the cases of CSOM and their antibiotic sensitivity patterns. This in turn will ensure rational and judicious use of antibiotics and thus prevent emergence of resistant bugs and also the complications associated with CSOM.</p>


2020 ◽  
Vol VOLUME 8 (ISSUE 2) ◽  
pp. 23-27
Author(s):  
Harendra Kumar Gautam

Abstract Background: Chronic suppurative otitis media (CSOM) remains one of the most common ear diseases in the general population. The socioeconomic burden of CSOM is still very high both nancially and non-nancially for the society. There is a need for capacity building to reduce the burden as well as the associated risk. Aims and Objectives: The aim of this study was to study the clinical and epidemiological prole of post operated patients of chronic suppurative otitis media (CSOM) at a tertiary care center. Materials and Methods: This was a retrospective study of 265 patients of clinically diagnosed CSOM. The study was carried out at the ENT department, LLR hospital, GSVM medical college Kanpur during the period of 6 years from August 2013 to July 2019. Results: The data collec ted from the Clinicoepidemiological study of chronic suppurative otitis media carried out on 265 patients, showed that 197 patients had unilateral ear disease while 68 patients had bilateral ear disease. Among 265 patients, 126 (47.54%) were male and 139 (52.42%) were female. 44.15% patients were in age group 11to20 years of age. 72.82% patients belonged to lower socioeconomic status. Tubotympanic type constituted majority 207 (78.12%) cases followed by atticoantral type in 58 (21.88%) cases. Most patients presented with moderate hearing impairment 113 (42.64%). Conclusion: CSOM is a preventable cause of hearing impairment. Early diagnosis and management can effectively reduce the socioeconomic burden and prevent deafness. Keywords: CSOM, Socioeconomic status, Hearing impairment


Author(s):  
P. Chaitanya ◽  
Rahul Magar

<p><strong>Background: </strong>Chronic suppurative otitis media (CSOM) is a disease of middle ear. The aim of this study is to know the antibiotic sensitivity pattern in CSOM cases attending to ENT out patient department (OPD) in a tertiary care hospital and device an appropriate antibiotic protocol to treat CSOM cases.</p><p><strong>Methods: </strong>This is a prospective observational study. Fifty-eight patients of CSOM who present to the ENT OPD with ear discharge will be studied. Ear swabs of these patients will be collected and sent to microbiology to know the causative bacteria and their drug susceptibility.</p><p><strong>Results: </strong>Of the 58 patients studied 64% were males and 36% were females. Of the organisms isolated Stap aureus (53%) was most common followed by <em>Pseudomonas</em> (36%). All the gram-positive organisms were sensitive to cotimaxozole, amikacin and gentamycin and all gram-negative organisms were sensitive to ciprofloxacin, amikacin and netlimycin. </p><p><strong>Conclusions: </strong>It is better to collect an ear swab in all CSOM cases and then start antibiotics based upon the culture and sensitivity reports in order to improve the results and reduce the emergence of resistant strains, which can happen when antibiotics are prescribed randomly.</p>


Author(s):  
Rashmi Ramashesh ◽  
Samira Abdul Wajid ◽  
Smitha Chandra

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is an ever growing concern of preventable hearing loss and is a major health concern especially in tropical countries. Lack of cleanliness, overcrowding, poverty, malnutrition and medical ignorance are few of the contributing factors. The microbiological flora is constantly changing due to indiscriminate use of antibiotics with rapid change in the antibiotic sensitivity patterns. Hence, this study was undertaken to determine the epidemiological profile, bacteriological profile and the antibiotic sensitivity pattern which would help in establishing a protocol in management of CSOM patients in the hospital.</p><p class="abstract"><strong>Methods:</strong> A total of 100 patients of CSOM attending the ENT Outpatient Department of The Oxford medical College, Hospital and Research Centre were included in the study. The samples were immediately sent to the Microbiology laboratory for further processing according to standard procedure.  </p><p class="abstract"><strong>Results:</strong> Out of 100 cases, 74 were active mucosal type and 26 were active squamous, with Pseudomonas species (33.6%) being the predominant organism. <em>Staphylococcus aureus</em> was the next common organism with MSSA (16.3%) and MRSA (12.5%), CONS were 6.7%. Among the 28 gram-negative bacilli, <em>Klebsiella pneumoniae</em> (7.7%), was followed by <em>Escherichia coli</em> (5.7%), and <em>Proteus mirabilis</em> (4.8%).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas species and <em>Staphylococcus aureus</em> are the commonest organisms of CSOM. Ciprofloxacin can be used as a topical agent for treating gram-negative bacilli. Among systemic antibiotics- Linezolid, Amikacin and Imepenam remains the drug of choice.</p><p><br /><br /></p>


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