scholarly journals Comparative study of fine needle Aspiration Cytology, Acid Fast Bacilli staining and Cartridge Based Nucleic Acid Amplification test in the diagnosis of extrapulmonary tuberculosis

2020 ◽  
Vol 5 (2) ◽  
pp. 151-156
Author(s):  
Mythreyi M U ◽  
◽  
M S Siddegowda ◽  
Shivakumar S ◽  
◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Extrapulmonary Tuberculosis ◽  
Needle Aspiration ◽  
Nucleic Acid Amplification Test ◽  
Nucleic Acid Amplification ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Cervical lymphadenopathy: scrofula revisited

2008 ◽  
Vol 123 (7) ◽  
pp. 764-767 ◽  
Author(s):  
R Khan ◽  
S H Harris ◽  
A K Verma ◽  
A Syed
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Extrapulmonary Tuberculosis ◽  
Cervical Lymphadenopathy ◽  
Polymerase Chain Reaction Analysis ◽  
Needle Aspiration ◽  
Cervical Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

AbstractBackground:The commonest form of extrapulmonary tuberculosis is tubercular cervical lymphadenitis, or scrofula.Methods and results:A total of 1827 patients with cervical lymphadenopathy who presented to various out-patients clinics of our institution were studied over a three-year period. Eight hundred and ninety-three (48.87 per cent) of these patients had lesions of tubercular origin. The most common observation was unilateral, matted adenopathy in female patients aged between 11 and 20 years and without constitutional symptoms of tuberculosis. Posterior triangle nodes were affected in 43.8 per cent of cases, followed by upper deep cervical nodes in 33.9 per cent. Fine needle aspiration cytology constituted the main diagnostic tool, with a positive yield in 90 per cent of patients. Polymerase chain reaction analysis was performed in 126 patients, with a sensitivity of 63 per cent. Only 18 per cent of patients had associated pulmonary tuberculosis, the rest having isolated involvement of cervical nodes. Medical treatment with anti-tubercular drugs for a period of six months formed the mainstay of treatment and cure. Surgical management was reserved for selected refractory patients.Conclusion:Tubercular cervical lymphadenitis can readily be diagnosed by fine needle aspiration cytology, a simple and cost-effective test. The disease can be cured completely by a short course of anti-tubercular chemotherapy, without surgical intervention.

Fine-needle aspiration cytology finding uric acid crystals produced by Aspergillus

2021 ◽  
pp. 004947552110301
Author(s):  
Anju Khairwa
Keyword(s):  
Uric Acid ◽  
Nucleic Acid ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Urate Oxidase ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Fungal Hyphae ◽  
Needle Aspiration Cytology

Uric acid is a metabolic product of nucleic acid and protein. Hyperuricemia results from failure or lack of urate oxidase. We present a case of a 61-year-old man with a painless forearm swelling, from which uric acid crystals were found on cytology. There were also septate fungal hyphae with morphology of Aspergillus, which has the source of the uric acid. Serum uric acid levels in our patient were normal.

Role of Fine Needle Aspiration Cytology in Extrapulmonary Tuberculosis

2021 ◽  
Vol 18 (2) ◽  
pp. 31-34
Author(s):  
Subarna Acharya ◽  
Sharmila Gupta
Keyword(s):  
Pulmonary Tuberculosis ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Extrapulmonary Tuberculosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Introduction: Extrapulmonary tuberculosis is equally important as that of pulmonary tuberculosis. Fine needle aspiration cytology (FNAC) is accurate, cost effective, minimal invasive outpatient procedure and aids in prompt diagnosis of extrapulmonary tuberculosis. Aims: To determine the role of fine needle aspiration cytology for diagnosis of extra pulmonary tuberculosis. Methods: This is a hospital based descriptive study done over a period of one and half year April 2019 to October 2020 at Nepalgunj Medical College Teaching Hospital, Nepalgunj, Nepal. All the 80 patients who were clinically suspected for tuberculosis had undergone fine needle aspiration cytology and diagnosed as tuberculosis in cytology were included in study. Cytological diagnosis was made with microscopic features and positive acid fast bacilli staining. Microscopy showed epithelioid histiocytes, granulomas, multinucleated giant cells, caseous necrosis, neutrophils and mature lymphocytes. Results: Out of 930 cases received, 80 cases were diagnosed as tuberculosis in cytology. 33 cases were diagnosed with acid fast bacilli positive. Rest was diagnosed with cytological features. Among 80 aspirated samples, a portion of purulent specimen was evaluated with Genexpert test in 11 cases for Mycobacterium Tuberculosis detection and rifampicin sensitivity/ resistant. Out of 11 positive patients in Genexpert tests; 10 were rifampicin sensitive and one was rifampicin resistant. Conclusion: Common presentation of extrapulmonary tuberculosis is in lymph nodes with increased frequency in age group of 21 to 30 years. Therefore, lymph nodes in this age group should be prioritized more for investigation of extrapulmonary tuberculosis.

Role of fine needle aspiration cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118

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