scholarly journals Investigating the Unexpected Behavior for the Release Kinetics of Brilliant Blue Encapsulated into Calcium Alginate Beads

2009 ◽  
Vol 12 (1) ◽  
pp. 69 ◽  
Author(s):  
Magdy M. Elnashar ◽  
Mohamed A. Yassin ◽  
Abou El-Fetouh Abdel Moneim ◽  
Elsayed M. Abdel Bary
Keyword(s):  
Calcium Alginate ◽  
Release Kinetics ◽  
Alginate Beads ◽  
Brilliant Blue ◽  
Unusual Behavior ◽  
Calcium Alginate Beads ◽  
Alginate Concentration ◽  
Optimum Formulation ◽  
Kinetics Of ◽  
Unexpected Behavior

This work is focused on investigating the unexpected behavior for the release kinetics of brilliant blue (BB) encapsulated into calcium alginate beads. By increasing the alginate concentration from 1-3% (w/v), the release of BB over time was found to follow two different behaviors. For the first two hours, the order was 1% > 2% > 3%, after which it was as follow: 1% > 3% > 2%. The unanticipated increase in BB release using 3% (w/v) alginate beads after two hours over that of 2% (w/v) alginate was examined by the swelling and bursting tests. The results were showing clear evidences by data and image the unusual behavior of 3% (w/v) alginate beads at two hours of swelling. This unexpected behavior for the 3% (w/v) alginate beads might be due to the higher osmotic pressure inside the beads. Overall, 2% (w/v) calcium alginate beads were considered to be the optimum formulation showing an excellent carrier for targeting drugs to the intestine, where the swelling of the beads were 60 % in the acidic medium, it was 5000 % in the alkaline medium.

Effects of Drying Methods on the Release Kinetics of Vitamin B12in Calcium Alginate Beads

2009 ◽  
Vol 27 (11) ◽  
pp. 1258-1265 ◽  
Author(s):  
Nada Abubakr ◽  
Sean Xuqi Lin ◽  
Xiao Dong Chen
Keyword(s):  
Calcium Alginate ◽  
Release Kinetics ◽  
Alginate Beads ◽  
Drying Methods ◽  
Calcium Alginate Beads ◽  
Kinetics Of

Viability and delivery of immobilised Lactobacillus reuteri DPC16 within calcium alginate gel systems during sequential passage through simulated gastrointestinal fluids

2011 ◽  
Vol 2 (2) ◽  
pp. 129-138 ◽  
Author(s):  
Q. Zhao ◽  
S. Lee ◽  
A. Mutukumira ◽  
I. Maddox ◽  
Q. Shu
Keyword(s):  
Calcium Alginate ◽  
Lactobacillus Reuteri ◽  
Skim Milk ◽  
Alginate Beads ◽  
Simulated Gastric Fluid ◽  
Gi Tract ◽  
Calcium Alginate Beads ◽  
Alginate Gel ◽  
Alginate Concentration ◽  
Calcium Alginate Gel

The objective of the study was to design and produce calcium alginate beads that can deliver immobilised Lactobacillus reuteri DPC16 to a target site of the colon in the gastrointestinal (GI) tract. In this study, several factors that might affect the effectiveness of calcium alginate gel beads entrapping L. reuteri DPC16 cells were investigated. An in vitro GI tract model was used to simulate the pH variation and the existence of enzymes. Firstly, by varying the concentration of alginate at a constant concentration of CaCl2 the survival of immobilised DPC16 cells in simulated gastric fluid (SGF) was observed; secondly, the physical stability of calcium alginate beads containing skim milk during sequential incubation in the GI fluids was observed using optimal concentrations of alginate; finally, the survival of DPC16 cells immobilised within alginate beads containing skim milk were compared when the beads were incubated for different times during sequential exposure to the simulated fluids. The results demonstrated that non-encapsulated DPC16 cells were sensitive to an acidic environment, and no viable cells were detected after 90 min exposure in SGF (pH 1.2). With the protection of calcium alginate gel, the survival rate of immobilised DPC16 cells was slightly improved. An alginate concentration of 4% (w/v) was the most effective of those tested, but due to the irregular shape it formed, an alginate concentration of 3% (w/v) was used in further investigations. When skim milk (8% (w/v)) was added to the alginate solution, the cell survival was improved markedly. The optimal concentration of calcium chloride was 0.3 M, because the beads maintained their integrity in SGF and simulated intestinal fluid while disintegrating in simulated colonic fluid. The beads made from 3% alginate, 8% skim milk and 0.3 M CaCl2 proved to be an effective delivery and release system for DPC16 cells.

scholarly journals INMOVILIZACIÓN DE LAS MICROALGAS Scenedesmus ovalternus (Scenedesmaceae) Y Chlorella vulgaris (Chlorellaceae) EN ESFERAS DE ALGINATO DE CALCIO

2016 ◽  
Vol 21 (2) ◽  
pp. 437-442
Author(s):  
Mario Andres Forero-Cujiño ◽  
Luis Carlos Montengro Ruiz ◽  
Gabriel Antonio Pinilla-Agudelo ◽  
Luz Marina Melgarejo-Muñoz
Keyword(s):  
Growth Rate ◽  
Population Density ◽  
Chlorella Vulgaris ◽  
Calcium Alginate ◽  
Alginate Beads ◽  
Calcium Alginate Beads ◽  
The Stability ◽  
Kinetics Of

<p>En este trabajo se describe la técnica de inmovilización de microalgas en esferas de alginato de calcio. Se emplearon las especies Scenedesmus ovalternus y Chlorella vulgaris, se determinó la estabilidad de las esferas, la cinética de crecimiento y la concentración de las microalgas en el interior de las esferas. Chlorella vulgaris alcanzó mayores densidades poblacionales y tasas de crecimiento más altas cuando se inmovilizó en concentraciones del 10 % v/v con el alginato (1,31*10<span>6 </span>cél/ml). Para Scenedesmus ovalternus se observó una mayor densidad poblacional y una mayor tasa de crecimiento cuando se inmovilizó en concentraciones del 20 % v/v (7,06*10<span>5 </span>cél/ml). Estos resultados son útiles para aplicaciones prácticas de las algas encapsuladas, tales como el biomonitoreo o la biorremediación.</p><p><strong>Immobilization of Microalgae<em> Scenedesmus ovalternus</em> (Scenedesmaceae) and <em>Chlorella vulgaris</em> (Chlorellaceae) in Calcium Alginate Beads</strong></p><p>This paper describes the immobilization technique of microalgae in calcium alginate beads. Scenedesmus ovalternus and Chlorella vulgaris species were used. The stability of beads, the kinetics of growth and the concentrations of microalgae inside the beads were determined. The higher density and the upper growth rate of Chlorella vulgaris occurred when it was immobilized in alginate at a concentration of 10 %v/v (1,31*10<span>6 </span>cél/ml). Scenedesmus ovalternus achieved a higher population density and an elevated growth rate when it was immobilized at a concentration of 20 % v/v (7,06*10<span>5 </span>cél/ml). These results are useful for subsequent applications of the encapsulated algae, such as biomonitoring and bioremediation.</p>

scholarly journals Alginate-pomegranate peels' polyphenols beads: effects of formulation parameters on loading efficiency

2014 ◽  
Vol 50 (4) ◽  
pp. 741-748 ◽  
Author(s):  
Wissam Zam ◽  
Ghada Bashour ◽  
Wassim Abdelwahed ◽  
Warid Khayata
Keyword(s):  
Sodium Alginate ◽  
Calcium Chloride ◽  
Calcium Alginate ◽  
Chloride Concentration ◽  
Natural Antioxidants ◽  
Alginate Beads ◽  
Food Supplementation ◽  
Calcium Alginate Beads ◽  
Loading Efficiency ◽  
Alginate Concentration

Calcium alginate beads containing pomegranate peels' polyphenol extract were encapsulated by ionic gelation method. The effects of various formulation factors (sodium alginate concentration, calcium chloride concentration, calcium chloride exposure time, gelling bath time maintaining, and extract concentration) on the efficiency of extract loading were investigated. The formulation containing an extract of 1 g pomegranate peels in 100 mL distilled water encapsulated with 3 % of sodium alginate cured in 0.05 M calcium chloride for 20 minutes and kept in a gelling bath for 15 minutes was chosen as the best formula regarding the loading efficiency. These optimized conditions allowed the encapsulation of 43.90% of total extracted polyphenols and 46.34 % of total extracted proanthocyanidins. Microencapsulation of pomegranate peels' extract in calcium alginate beads is a promising technique for pharmaceutical and food supplementation with natural antioxidants.

SHRINKING KINETICS OF CALCIUM ALGINATE BEADS IN ALCOHOLIC SODA

1982 ◽  
Vol 15 (1-4) ◽  
pp. 197-206 ◽  
Author(s):  
F. FERRERO ◽  
P. CAMPAGNA ◽  
N. PICCrNINI
Keyword(s):  
Calcium Alginate ◽  
Alginate Beads ◽  
Calcium Alginate Beads ◽  
Kinetics Of

Effects of encapsulation process parameters of calcium alginate beads on Vitamin B12drug release kinetics

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Nada Abubakr ◽  
Amanthi Jayemanne ◽  
Niken Audrey ◽  
Sean Xuqi Lin ◽  
Xiao Dong Chen
Keyword(s):  
Process Parameters ◽  
Calcium Alginate ◽  
Release Kinetics ◽  
Alginate Beads ◽  
Calcium Alginate Beads ◽  
Encapsulation Process

Release characteristics of brilliant blue from calcium-alginate beads coated with quaternized chitosan

2006 ◽  
Vol 23 (4) ◽  
pp. 405-415 ◽  
Author(s):  
X.-W. Shi ◽  
Y.-M. Du ◽  
J. Li ◽  
X.-L. Su ◽  
J.-H. Yang
Keyword(s):  
Calcium Alginate ◽  
Alginate Beads ◽  
Brilliant Blue ◽  
Calcium Alginate Beads ◽  
Quaternized Chitosan

scholarly journals Removal of Lead from Water Using Calcium Alginate Beads Doped with Hydrazine Sulphate-Activated Red Mud as Adsorbent

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
A. Naga Babu ◽  
G. V. Krishna Mohan ◽  
K. Kalpana ◽  
K. Ravindhranath
Keyword(s):  
Red Mud ◽  
Calcium Alginate ◽  
Surface Characterization ◽  
Complete Removal ◽  
Alginate Beads ◽  
Lead Extraction ◽  
Kinetics Of Adsorption ◽  
Calcium Alginate Beads ◽  
Hydrazine Sulphate ◽  
Kinetics Of

Calcium alginate beads doped with hydrazine sulphate-treated red mud are investigated as adsorbent for extracting lead ions from water using batch methods of extraction. Different extraction conditions are optimised for maximum lead extraction. Substantial amount of lead is removed, and the adsorption ability is found to be 138.6 mg/g. Surface characterization using FTIR, EDX, and FESEM confirms that lead is “onto” the surface of the adsorbent. Thermodynamic parameters, adsorption isotherms, and kinetics of adsorption are analysed. Adsorption is “physisorption” in nature and spontaneous. The adsorbent developed can be regenerated using 0.1 M HCl. Thus regenerated adsorbent can be used as the adsorbent for further removal of lead at least 10 times, and this enables the complete removal of lead from water by repetitive use of the regenerated adsorbent. The beads facilitate the easy filtration. The methodology developed is successfully applied for removing lead from industrial waste waters.

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