scholarly journals Cutaneous Manifestations of Diabetes Mellitus in a Tertiary Care Hospital in Bengaluru – A Cross Sectional Study

2021 ◽  
Vol 8 (19) ◽  
pp. 1352-1356
Author(s):  
Kavana K ◽  
Sharath Kumar B.C

BACKGROUND “Skin is a mirror of internal diseases”. Diabetes mellitus (DM) is a metabolic disorder that needs considerations of many different specialities but the importance of dermatologist’s knowledge has not drawn much attention. As a result, we intend to study various cutaneous manifestation of diabetes mellitus. Prior to diagnosis of diabetes mellitus, patient may present with cutaneous manifestation. Thus, it can help in early diagnosis, management and prevention of complication and help in improvement of quality of life. METHODS This is a descriptive cross-sectional study. A total of 500 diabetic patients with cutaneous manifestations, who attended skin outpatient department (OPD) at Kempegowda Institute of Medical Sciences Hospital and Research Centre, Bengaluru, Karnataka, India, were evaluated. Detailed history was taken along with physical and mucocutaneous examination. Cutaneous manifestations, general description of diabetes mellitus like duration, type, and drug history as well as the demographic data were collected and analysed using descriptive statistics. RESULTS Among a total of 500 diabetes mellitus subjects, the most common cutaneous manifestations were infections (35 %) followed by pruritus (11 %). Among infections, tinea infections (48.29 %) were the most common followed by intertrigo (21 %). CONCLUSIONS The ignorance of skin manifestations in diabetes or improper treatment may worsen the condition. Early detection and treatment of common skin manifestations in diabetes will prevent further complications especially in cases of extensive tinea corporis, pruritus, psoriasis, lichen planus, macro and micro angiopathies, trophic ulcers etc. KEYWORDS Cutaneous manifestations, Diabetes mellitus

Author(s):  
Sujeet A. Divhare ◽  
Satyashil Ingale

Background: Potential importance of drug –drug interactions (DDIs) is increasing as polypharmacy becomes more prevalent. Because additional data on the incidence and pattern of potential DDIs among diabetic patients are lacking in India, and supplemental pharmacodynamic or clinical outcome information is needed to address importance of a drug- drug interaction. Aim and objectives: To identify and analyze the pattern of DDIs in patients being prescribed anti-diabetic drugs in a tertiary care hospital. Material and Methods: This prospective cross-sectional study was carried out for a period of three months in 200 Type 2 diabetes mellitus (Type 2 DM) patients who were taking at least one antidiabetic agent during the period of past six months, of any age and either sex admitted in medicine ward of a tertiary care teaching hospital. Only one prescription was included for each patient on his/her 3rd day of hospitalization in the ward. Results: A total of 1217 drugs were prescribed in 200 prescriptions, resulting in an average of 6.1 drugs per prescription. A total of 637 potential DDIs were noted. The majority were seen in middle aged and elderly people. No overall difference was detected in the patients on insulin or metformin therapy taking or not taking additional drugs with the potential to interact. Worse control was found in the group of patients on sulphonylurea therapy taking interacting drugs (P <0.05). This difference was most marked in the group of patients over 60 years of age, who also had the highest intake of potentially interacting drugs (57%; <35 years-37%). Conclusion: Antidiabetic drugs have numerous interactions. A good practice is to use a drug­–drug interaction checker if any questions arise, several are available online. Quality care starts with the clinician obtaining a complete medication list for each patient at the start of each visit. Keywords: diabetes mellitus, drug interactions, hypoglycemic agents, drug therapy, co-morbidity, polypharmacy


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Hasan Mahmud Reza ◽  
Towhid Hasan ◽  
Marjia Sultana ◽  
Md. Omar Faruque

Purpose Diabetes mellitus is becoming a growing concern worldwide. Hence, the purpose of this study is to assess the magnitude of poor glycemic control and to identify the determinants of poor glycemic control among diabetic patients attending a tertiary care hospital in Bangladesh. Design/methodology/approach This cross-sectional study was conducted among 732 diabetes patients seeking care at the outpatient department of Bangladesh Institute of Health Sciences Hospital, Dhaka, Bangladesh. Information, including glycemic status, was collected from patients’ medical records using a structured questionnaire. Findings About 87.6% of the patients were found to have poor glycemic control (glycosylated hemoglobin = 7%). Variables that were significant in bivariate analysis were put into a multivariate model where the factors associated with poor glycemic control were patients aged 41–60 years (odds ratio (OR)=2.26; 95% confidence interval (CI): 1.19–4.32, p = 0.013), suffering from diabetes for > 7 years (OR = 1.84; 95% CI: 1.12–2.99, p = 0.015), using insulin (OR = 2.34; 95% CI: 1.23–4.47; p = 0.010) or diet alone (OR = 0.20; 95% CI: 0.05–0.80, p = 0.023) as a type of diabetes treatment and proper use of medicine (OR = 0.37; 95% CI: 0.17–0.82, p = 0.015). Originality/value The high prevalence of poor glycemic control among diabetic patients is evident; therefore, strategic management and proper attention focusing on the predictors of poor glycemic control are necessary to reduce the long-term complications of diabetes.


Author(s):  
Kumara Lakshmanan Sengotuven ◽  
Rangaraj Murugaiyan ◽  
Karthikeyan Kaliaperumal

<p class="abstract"><strong>Background:</strong> Alcoholism is a chronic fatal disease of worldwide concern. Alcohol abuse can present in a variety of ways, and dermatological disease is emerging as an important marker of alcohol misuse. The aim is to find out the various skin manifestations associated in chronic alcoholics, to find out the most common skin manifestations among chronic alcoholics and to identify the early skin changes in chronic alcoholics.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study conducted in patients attending medicine, psychiatry and dermatology clinics at a tertiary care centre, Puducherry. Inclusion criteria were patients with history of chronic alcoholism, aged above 18 years. After obtaining history, cutaneous examination was done including skin, mucosa, hairs, and nails. Alcohol dependency pattern was calculated using short alcohol dependency score (SADD).<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 130 patients were included. All were male and 59.2% of them belonged to high dependency pattern. About 128 of them had dermatological manifestations pityriasis versicolor was the most common dermatoses followed by psoriasis. Alcohol specific dermatoses were not seen in our study.</p><p><strong>Conclusions:</strong> In our study, 98.4% of alcoholics had skin manifestations, of which cutaneous infections were the most common. </p>


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