scholarly journals Some aspects of the use of genetically engineered biological products for the treatment of psoriasis

2019 ◽  
Author(s):  
R.G. Tuhbatullina ◽  
A.F. Latypova
Author(s):  
Asmuni Asmuni ◽  
Syahnan Syahnan ◽  
Asyura Asyura

Products are "goods and / or services related to food, beverages, drugs, cosmetics, chemical products, biological products, genetically engineered products, as well as used goods that are used, used or utilized by the public", while the halal certificate is a certificate issued by the Central or Provincial MUI regarding the case of a food product, foodstuff, beverage and medicine and cosmetics produced by the company after being examined and declared halal by an institution authorized to issue a halal product certification. In Article 4 of Law No. 33 of 2014 concerning the guarantee of halal products it states that "Products that enter, circulate and are traded in the territory of Indonesia must be certified halal". Normatively, the article clearly stipulates that drugs that enter, circulate and are traded in the territory of Indonesia must be guaranteed halal. However, the halal certification process for medicines in Indonesia is waiting for a long time due to various dynamics, this is the content of researchers seeing the gap between Law Number 33 of 2014 and the current reality, we should be able to reflect on other countries as well. Which is more advanced than Indonesia regarding halal certification?


Author(s):  
Asmuni Asmuni ◽  
M. Jamil ◽  
Fitri Rafianti

Products are "goods and / or services related to food, beverages, drugs, cosmetics, chemical products, biological products, genetically engineered products, as well as used goods that are used, used or utilized by the public", while the halal certificate is a certificate issued by the Central or Provincial MUI regarding the case of a food product, foodstuff, beverage and medicine and cosmetics produced by the company after being examined and declared halal by an institution authorized to issue a halal product certification. In Article 4 of Law No. 33 of 2014 concerning the guarantee of halal products it states that "Products that enter, circulate and are traded in the territory of Indonesia must be certified halal". Normatively, the article clearly stipulates that drugs that enter, circulate and are traded in the territory of Indonesia must be guaranteed halal. However, the halal certification process for medicines in Indonesia is waiting for a long time due to various dynamics, this is the content of researchers seeing the gap between Law Number 33 of 2014 and the current reality, we should be able to reflect on other countries as well. Which 


2019 ◽  
Vol 1 (7) ◽  
pp. 5-8
Author(s):  
L. S. Kruglova ◽  
A. A. Osina ◽  
A. A. Khotko

Among patients with psoriasis, approximately 50% are women and almost 75 % of them are under the age of 40 years. Thus, most women with psoriasis have childbearing potential. When pregnancy occurs in 22 % of patients, the activity of psoriasis persists, characteristic of the course before pregnancy, in 23 % of women, the course of the disease worsens. The article provides up-to-date data on the management of pregnant patients with psoriasis. To improve pregnancy outcomes in patients with psoriasis, it is important to prevent exacerbation of the disease. The choice of drug therapy in this case is based on an assessment of the ratio of the risk of undesirable effects of the drugs on the developing fetus and the risk of the development of exacerbation of psoriasis, which can cause an adverse pregnancy outcome. Despite the fact that the available clinical experience of using genetically engineered drugs is still limited, with a certain degree of confidence we can say that there is no increase in the risk of adverse pregnancy outcomes associated with therapy with certolizumab pegol.


2003 ◽  
Vol 773 ◽  
Author(s):  
Aaron R. Clapp ◽  
Igor L. Medintz ◽  
J. Matthew Mauro ◽  
Hedi Mattoussi

AbstractLuminescent CdSe-ZnS core-shell quantum dot (QD) bioconjugates were used as energy donors in fluorescent resonance energy transfer (FRET) binding assays. The QDs were coated with saturating amounts of genetically engineered maltose binding protein (MBP) using a noncovalent immobilization process, and Cy3 organic dyes covalently attached at a specific sequence to MBP were used as energy acceptor molecules. Energy transfer efficiency was measured as a function of the MBP-Cy3/QD molar ratio for two different donor fluorescence emissions (different QD core sizes). Apparent donor-acceptor distances were determined from these FRET studies, and the measured distances are consistent with QD-protein conjugate dimensions previously determined from structural studies.


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