scholarly journals THE QUALITY OF LIFE OF PATIENTS WITH SYMPTOMS OF TEMPOROMANDIBULAR DISORDER IN INTEGRATED DENTAL ORTHOPEDIC REHABILITATION

2020 ◽  
Vol 16 (2) ◽  
pp. 144-150
Author(s):  
Sergey Chikunov ◽  
Fatima Dzalaeva ◽  
Anatoliy Utyuzh ◽  
Zarina Dzhagaeva ◽  
Aleksey Yumashev

Subject ― is adentia and dysfunction of the temporomandibular joint. Goal ― based on the quality of life indicators, to evaluate the efficiency of various approaches to dental orthopedic treatment of patients with adentia and temporomandibular disorder, who need a full mouth reconstruction. Methodology. A total pf 647 patients with adentia and a need for full mouth reconstruction were assigned to a comprehensive examination and treatment. Patients were divided into 3 groups. Group 1 (n = 218) was exposed to standard treatment procedures. Group 2 (n = 195) was given certain elements of the interdisciplinary approach to dental orthopedic rehabilitation. Group 3 (n = 234) was exposed to interdisciplinary approach towards dental orthopedic rehabilitation. The follow-up period was 7 years. A key step in the treatment of group 3 patients was to conduct full patient examinations sequentially. The corresponding procedures were supplemented with a temporomandibular disorder test. In treatment planning, the cause-and-effect relationships between this disorder and malocclusion were identified. Results. The improvement in temporomandibular joint after the interdisciplinary approach manifested in changes that were statistically significant (relative to those in the comparison groups). Pain sensations in the joint decreased as reported on the VAS score. The OHIP-14 subscale scores showed a downward trend that was more pronounced as compared with the standard procedure group, which indicates an improvement in the quality of life of patients. Conclusion. The use of interdisciplinary approach in dental orthopedic rehabilitation contributes to a prominent and persistent improvement in the dental quality of life of patients with adentia, who need a full mouth reconstruction.

Author(s):  
F.K. Dzalaeva ◽  
Chikunov S.O. Chikunov S.O. ◽  
A.S. Utyuzh ◽  
M.V. Mikhailova ◽  
A.V. Yumashev

Aim: based on occlusion and temporomandibular health indicators, to improve clinical effectiveness of dental orthopedic treatment of patients with a need for a full mouth reconstruction. Materials and methods. A total of 647 patients with adentia and a need for a full mouth reconstruction received comprehensive examination and treatment. Patients were divided into 3 groups. Group 1 (n=218) was exposed to standard treatment procedures. Group 2 (n=195) received certain elements of the interdisciplinary approach to dental orthopedic rehabilitation. Group 3 (n=234) was exposed to interdisciplinary approach towards dental orthopedic rehabilitation. The follow-up period was 7 years. A key step in the treatment of group 3 patients was to conduct full patient examinations sequentially. The corresponding procedures were supplemented with tests for temporomandibular disorder and occlusal relationships. In treatment planning, the cause-and-effect relationships between this disorder and malocclusion were identified. Results. It was found that the use of the present proposal contributes to the normalization of occlusion. For instance, the occlusal index dropped 2.1-fold (relative to that in the comparison groups). The frequency of ICP manifestations decreased by 2.1 to 4.3 times, the protrusion frequency decreased by 12.2 to 22.3 times, and the bruxism frequency became 4.8 to 5.2 times lower. Furthermore, the frequency of left and right mediotrusion detection dropped by 3.2—4.3 and 3.8—4.4 times, respectively. The revealed changes were persistent, and a positive effect maintained throughout the follow-up. Conclusion. The interdisciplinary approach to the restoration of the anatomical shape of teeth should involve the assessment and correction of occlusal disturbances.


2021 ◽  
Vol 2 (42) ◽  
pp. 52-62
Author(s):  
Saltanat Makhanova ◽  
◽  
Raushan Sekenova ◽  

The purpose of the study: analysis and assessment of the quality of life of glaucoma patients in Kazakhstan on the example of Balkhash. Methods. The study was conducted on the basis of the municipal state institution (KSU) "Polyclinic No. 2" of the city of Balkhash, Karaganda region in the period from 2019 to 2020. The study involved 46 men and 74 women. The average age of the respondents was ≥64 years. To determine the quality of life of glaucoma patients, we conducted a questionnaire compiled by ourselves and the NEI VFQ-25 questionnaire. The respondents were conditionally divided into three groups: group 1-patients who receive only conservative treatment; group 2 – patients who underwent laser correction in parallel with conservative treatment; group 3-patients who, in addition to previous types of treatment, were operated on. Results. Among the comparison groups, the values of indicators of dependence on the help of others (23.7) and role difficulties (23.9) and social activity (81.6) were significantly lower in patients receiving only conservative treatment. In this group, along with the physical and mental components, it was found that the gap in visual indicators is up to 4 times. Conclusions. The results of the study show that in glaucoma patients receiving only conservative treatment, the quality of life is low compared to the control groups according to all indicators of the scales. A significant impact on the decrease in the quality of life of patients receiving conservative treatment is caused by the discomfort associated with regular use of drugs prescribed for glaucoma and their side effects. Keywords: glaucoma, quality of life, NEI VFQ-256 questionnaire, Kazakhstan.


2020 ◽  
Vol 16 (2) ◽  
pp. 114-120
Author(s):  
Maria Mikhailova ◽  
Sergey Chikunov ◽  
Fatima Dzalaeva ◽  
Anatoliy Utyuzh ◽  
Aleksey Yumashev

Subject ― is a temporomandibular joint dysfunction. Goal ― to evaluate clinical effectiveness of an interdisciplinary approach towards dental orthopedic treatment of patients with obstructive sleep apnea and a need for a full mouth reconstruction. Methodology. A total of 95 patients (52 males and 43 females) with adentia, obstructive sleep apnea syndrome and temporomandibular disorder were assigned to comprehensive examination and treatment. All patients were in need for a full mouth reconstruction. Patients were divided into 3 groups. Group 1 (n = 32) was exposed to standard treatment procedures. Group 2 (n = 29) received certain elements of an interdisciplinary approach to dental orthopedic rehabilitation. Group 3 (n = 34) was exposed to multidisciplinary approach towards dental orthopedic rehabilitation. The follow-up period was 7 years. A key step in the treatment of group 3 patients was to conduct full patient examinations sequentially. The corresponding procedures were supplemented with a study of OSA manifestation patterns. Results. It was found that the use of the present proposal contributes to the normalization of the OSA picture in patients with temporomandibular disorder. For instance, the apnea-hypopnea index dropped, the basal nocturnal saturation increased, and the minimum saturation level decreased. Overall, the proportion of patients with better to favorable sleep increased. The revealed changes were persistent, and a positive effect was observed throughout the 5―7 years of follow-up. Conclusion. Performing restoration of the anatomical shape of the tooth with the interdisciplinary approach, the dentist should assess and relieve the manifestations of OSA while correcting the temporomandibular joint disturbances.


Pituitary ◽  
2021 ◽  
Author(s):  
Muhammad Fahad Arshad ◽  
Oluwafunto Ogunleye ◽  
Richard Ross ◽  
Miguel Debono

Abstract Purpose There is no consensus on quality of life (QOL) in patients with acromegaly requiring medical treatment after surgery compared with those achieving remission by surgery alone. Methods QuaLAT is a cross-sectional study comparing QOL in surgery-only treated acromegaly patients versus those requiring medical treatment post-surgery. Patients attending clinics were identified and divided into—Group 1: patients who had surgery only and were in biochemical remission, Group 2: all patients on medical treatment post-surgery, Group 3: patients from Group 2 with biochemical control. Participants were asked to fill three questionnaires; Acromegaly Quality of Life Questionnaire (ACROQOL), 36-Item Short Form Survey (SF36), and Fatigue Severity Scale (FSS). Results There were 32 patients in Group 1 and 25 in Group 2. There was no difference in QOL scores between groups 1 and 2, as measured by ACROQOL (mean difference [MD] = − 2.5, 95% CI − 16.6 to 11.6; p = 0.72), SF36v2 [Physical component score (PCS) MD = − 4.9, 95% CI − 10.9 to 1.2; p = 0.12; mental component score MD = − 3.0, 95% CI − 10.5 to 4.4; p = 0.44], or FSS (MD = − 0.004, 95% CI − 1.14 to 1.33; p = 0.1). Comparison between groups 1 and 3 however showed that PCS (and 3 subdomains) was significantly better in group 3 (MD = − 8.3, 95% CI − 14.8 to -1.8; p = 0.01). All three QOL scores were lower when compared with healthy controls. Conclusions Medical treatment not only achieves a QOL comparable to surgery, it may also be associated with better QOL in physical subdomains. When compared with healthy controls, QOL remains worse in treated acromegaly patients compared to controls.


Author(s):  
Fatima K. Dzalaeva ◽  
S. O. Chikunov ◽  
A. S. Utyuzh ◽  
M. V. Mikhailova ◽  
M. K. Budunova

Background. This study aimed to improve the clinical effect of dental orthopedic treatment for patients who need a complete dental reconstruction, by making use of the temporomandibular joint characteristics. Materials and Methods. A total of 647 patients with adentia who needed a complete dental reconstruction were exposed to a comprehensive examination and treatment. Patients were divided into 3 groups: orthopedic rehabilitation group (218 patients), interdisciplinary rehabilitation group (195 patients), and multidisciplinary rehabilitation group (234 patients). The follow-up period was 7 years. Results. After the proposed rehabilitation approach, patients in the main group demonstrated an improvement in the VAS (Visual Analogue Scale) score, which was significantly smaller with respect to that in the comparison groups. The frequency of clicking and pain during chewing as well as soreness sensations in this group decreased at a significantly lower pace compared to that in the comparison groups. Conclusions. Dental reconstruction procedures aimed at restoring the shape of the teeth should focus on pain relief and temporomandibular joint function correction. The most important stage in implementing this approach is a complete and consistent examination of patients who need dental reconstruction.


2014 ◽  
Vol 32 (31_suppl) ◽  
pp. 48-48
Author(s):  
Victor Tsu-Shih Chang ◽  
Charles B. Scott ◽  
Melanie L. Gonzalez ◽  
Jan Einhorn ◽  
Houling Yan ◽  
...  

48 Background: A Recursive Partitioning Analysis (RPA) prognostic algorithm based on quality of life and symptoms predicted 4 groups with distinct median survivals in patients with metastatic solid tumors receiving chemotherapy (ASCO 2013, Abst 9567). We update our findings. Methods: The RPA algorithm is based upon Karnofsky performance status (KPS), Functional Assessment of Cancer Therapy (FACT) physical well-being (PWB) subscale, and Memorial Symptom Assessment Scale Short Form (MSAS-SF) physical symptom distress (PHYS) subscale. Starting in 2007, a convenience sample of Veterans who were prescribed systemic treatment for their cancer was enrolled in an IRB approved protocol, and completed quality of life (FACT- G) and symptom (MSAS SF) questionnaires at the first cycle of treatment. We analyzed records of patients with stage IV metastatic solid tumors enrolled through June 2013, and determined survival as of June 15, 2014. Analyses were performed with STATA 11.0. Results: There were 97 patients(pts). The median age was 64 yrs, range 27-88. Males comprised 95 (98%) pts. First line chemotherapy was given to 78 (80%) pts. The most common primary sites were lung cancer 33 (35%), prostate 17 (17%) and colon 11 (11%) pts. Median KPS was 90% range 40-100%, PWB median 23 (range 6-28), and MSAS SF median PHYS 0.76 (range 0-3.2). Overall median survival was 285 days (range 6-2,358) and 80 pts (82%) had died. There was 1 pt in group 1, 58 in group 2, 12 in group 3, and 23 in group 4. The patient in group 1 had uterine sarcoma. Median survival (days) by RPA group was 155 for group 1, 177 for group 2, 292 for group 3, and 674 for group 4 (p=.011). Conclusions: These preliminary findings suggest that this algorithm is capable of dividing patients with metastatic solid tumor who are starting systemic therapy into prognostic groups. Further development is indicated.


2020 ◽  
Vol 78 (5) ◽  
pp. 255-261 ◽  
Author(s):  
Prabhat VARSHNEY ◽  
Rizwana PARVEEN ◽  
Mohd Ashif KHAN ◽  
Sunil KOHLI ◽  
Nidhi B. AGARWAL

ABSTRACT Background: Co-morbid diabetes and depression are prevalent chronic conditions negatively affecting quality of life (QoL). Inflammation has been considered as an integral mechanism in patients with both diabetes and depression. Objective: The aim of the present study was to investigate depression and its association with interleukins (IL)-1β and IL-9 in type 2 diabetic patients (T2DM) and controls. The QoL in diabetic patient was also assessed. Methods: Eighty subjects were included, distributed among three groups: Group 1 - Healthy controls; Group 2 - T2DM patients without depression; Group 3 - T2DM patients with depression. Depression and QoL were assessed using Patient Health Questionnaire (PHQ-9) and The Audit of Diabetes-Dependent QoL (ADDQoL), respectively. IL-1β and IL-9 were measured in serum samples of all the patients using ELISA kit. Results: The PHQ score in the Group 3 was significantly higher as compared to Group 1. The ADDQoL scores in the Group 3 were significantly higher as compared to Group 2. Levels of IL-9 and IL-1β were elevated in Group 3, as compared to the other groups. Conclusion: This study showed positive association between depression and IL-1β, IL-9 in T2DM patients. Additionally, the diabetic patients have poorer quality of life, which is further worsened by the presence of depression. Thus, routine assessment for the presence of depression is suggested in T2DM patients.


Author(s):  
N. L. Perelman

Aim. To compare the nature and degree of influence of different types of airway hyperresponsiveness (AHR) on the general and specific quality of life (QoL) of patients with asthma and control over the disease.Materials and methods. 234 patients with mild-to-moderate asthma, aged from 18 to 60 years old, were interviewed and examined. Depending on the presence of one or another type of AHR, 4 groups were formed: group 1 included 60 patients with cold AHR, group 2 – 75 patients with hypoosmotic AHR, group 3 – 35 patients with hyperosmotic AHR, group 4 – 64 patients with exercise-induced bronchoconstriction (EIB). QoL and the state of the emotional sphere were assessed using the SF-36, AQLQ, HADS questionnaires. The level of asthma control was determined using the ACT questionnaire. Lung function was assessed by spirometry.Results. When comparing QoL between groups, statistical differences were obtained for most of the SF-36 scales, with the exception of the domains “Role Physical” (RP) and “Bodily Pain” (BP), and their presence and significance varied depending on the types of AHR being compared. The lowest QoL indices were found in group 1 of patients with cold AHR according to the domains “Physical Activity” (PA), RP, BP, and “Role Emotional” (RE). The lowest indices for the domains “General Health” (GH), “Vitality” (V) and “Mental health” (MH) were found in the respondents of the 2nd group. Most of the highest QoL indicators in the compared groups were found in patients of group 4 with EIB in the domains PA, RP, V, RE, and MH. When carrying out a comparative analysis, the maximum number of significant differences was found between the groups with cold AHR and EIB. A comparative study of QoL using a special AQLQ questionnaire showed the lowest indices for the “Activity” and “Symptoms” domains in groups 1 and 2 of asthma patients. In addition, in group 1, the minimum QoL values were recorded for the “General QoL” domain (3.6±0.2 points), and in group 2, for the “Environment” domain (2.9±0.3 compared with 3.9±0.2 points in group 3, p<0.01).Conclusion. This study has demonstrated the multifaceted effect of AHR on health-related QoL, dependent on sensitivity to a particular physical stimulus and the season of maximum trigger action. The subjective assessment of psychosocial functioning is most differentiated according to the GH domain of the SF-36 questionnaire. The greatest negative impact on the QoL indices is exerted by the cold and hypoosmotic AHR, the least – by the EIB. The assessment of QoL allows to get a full picture of the perception of the patient's health level at the moment and in the given conditions.


2019 ◽  
Vol 13 (4) ◽  
pp. 640-646 ◽  
Author(s):  
Masahiko Yazawa ◽  
Kenji Omae ◽  
Yugo Shibagaki ◽  
Masaaki Inaba ◽  
Kazuhiko Tsuruya ◽  
...  

Abstract Background For hemodialysis (HD) patients, travel to the dialysis facility is an issue that can affect their quality of life (QOL), both physically and mentally. However, evidence on this association of transportation modality with health-related QOL (HRQOL) is scarce. Methods We conducted a cohort study among maintenance HD patients participating in the Japanese Dialysis Outcomes and Practice Pattern Study Phase 5. The study included patients who were functionally independent and able to walk. The primary exposure was the means of transportation to the dialysis facility, categorized into three groups, namely transportation by other drivers (Group 1), transportation via self-driving (Group 2) and transportation by bicycle or walking with or without public transportation (Group 3). The primary outcomes were physical and mental health composite scores (PCS and MCS) in the 12-item Short Form at 1 year after study initiation. Results Among 1225 eligible patients (Group 1, 34.4%; Group 2, 45.0%; Group 3, 20.7%), 835 were analyzed for the primary outcomes. Linear regression analyses revealed that patients in Groups 2 and 3 had significantly higher PCS and MCS at 1 year than those in Group 1 {adjusted mean differences of PCS 1.42 [95% confidence interval (CI) 0.17–2.68] and 1.94 [95% CI 0.65–3.23], respectively, and adjusted mean differences of MCS 2.53 [95% CI 0.92–4.14] and 2.20 [95% CI 0.45–3.95], respectively}. Conclusions Transportation modality was a significant prognostic factor for both PCS and MCS after 1 year in maintenance HD patients.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Andrew W Gardner ◽  
Polly Montgomery ◽  
Ming Wang ◽  
Biyi Shen

Introduction: The aims were to determine (a) whether patients with peripheral artery disease (PAD) who walked at least 7,000 and 10,000 steps/day had better ambulatory function and health-related quality of life (HRQoL) than patients who walked less than 7,000 steps/day, and (b) whether these group differences persisted after adjusting for covariates. Hypothesis: Patients who walk at least 7,000 steps/day have significantly better ambulatory function, as measured by greater 6-minute walk distance (6MWD), and better HRQoL, as measured by a higher distance score on the Walking Impairment Questionnaire (WIQ), than patients who walked less than 7,000 steps/day, and that patients who walked more than 10,000 steps/day would have the best values. Furthermore, group differences in the primary outcomes would persist after adjustment for covariates. Methods: Two hundred forty-eight patients were assessed on their daily activity for one week with a step activity monitor, and were grouped according to daily step counts as follows: Group 1 (<7,000 steps/day; n=153), Group 2 (7,000-9,999 steps/day; n=57), Group 3 (>10,000 steps/day; n=38). Primary outcomes were 6MWD and WIQ distance score, which is a disease-specific measurement of HRQoL. Results: Groups were different (p<0.05) on ankle/brachial index, and on prevalence of hypertension, diabetes, abdominal obesity, arthritis, and chronic obstructive pulmonary disease. Thus, these variables served as covariates in adjusted analyses, along with age, weight, and sex. 6MWD (mean±SD) was significantly different among the groups in unadjusted (p<0.01) and adjusted (p<0.01) analyses (Group 1=313±90 m, Group 2=378±84 m, Group 3=414±77 m), with Groups 2 and 3 having higher 6MWD than Group 1 (p<0.01). Similar results were found for the WIQ distance score (Group 1=30±30%, Group 2=45±35%, Group 3=47±34%; p<0.01). Conclusions: PAD patients who walked more than 7,000 and 10,000 steps/day had greater ambulatory function and HRQoL than patients who walked fewer than 7,000 steps/day, and this finding persisted after adjusting for covariates. The clinical significance is that PAD patients should be encouraged to walk more than 7,000 steps/day because this target is associated with greater ambulatory function and HRQoL


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