Prevalence of aeroallergens and food allergens in allergic patients in Tehran, Iran

2018 ◽  
Author(s):  
Nasrin Pazoki ◽  
Ali Ahmadi ◽  
Fatemeh Onsori ◽  
Mohsen Mosavi Khorshidi ◽  
Mahboubeh Mansori ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
Egg Yolk ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Food Allergens ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prick Test ◽  
Allergy And Immunology ◽  
Allergen Extracts

Background and Aims: Identification of different allergens is a major challenge in allergic diseases. Avoiding these allergens is known as one of the best types of treatment. The aim of this study is to determine the prevalence of aeroallergens and food allergens in patients with allergy by Skin Prick Test. Materials and Methods: A cross-sectional study was conducted on 255 patients with allergic diseases who had referred to the Khorshid Allergy and Immunology Clinic. Skin Prick Test was performed using 82 allergen extracts to determine the patients' sensitivity to food and aeroallergens. Results: One hundred percent of the patients were sensitive to at least one allergen. Allergy to food allergens and aeroallergens was 49% and 51 %, respectively. Most sensitivity to food allergens included hazelnut (26.27%), bananas (21.96%), egg yolk (21.56%) and wheat (20.39%). Among the aeroallergens, grass with a frequency of 87% and fungi with a frequency of 34% had the highest and lowest frequencies. Conclusion: Depending on the nutrition, cultural habits, environmental conditions, and life style, prevalence of the allergens in each area may be different. Therefore, early identification and avoidance from these allergens can be suggested.

scholarly journals Evaluation of skin prick test reactivity in children with allergic diseases: A cross sectional study

2021 ◽  
Vol 4 (1) ◽  
pp. 85-88
Author(s):  
Dr. K Pavan Kumar ◽  
Dr. RSV Srikrishna ◽  
Dr. Indira Pavan ◽  
Dr. M Surendranath ◽  
Dr. Major Nagaraju
Keyword(s):  
Skin Prick Test ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prick Test

scholarly journals Soil-transmitted helminth infection and skin prick test reactivity in children

2014 ◽  
Vol 54 (1) ◽  
pp. 52
Author(s):  
Schenny Regina Lubis ◽  
Lily Lrsa ◽  
Rita Evalina ◽  
Supriatmo Supriatmo ◽  
M. Sjabaroeddin
Keyword(s):  
Skin Prick Test ◽  
Urban Areas ◽  
Allergic Diseases ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Stool Examination ◽  
School Students ◽  
Chi Square ◽  
Cross Sectional ◽  
Prick Test

Background Allergic diseases cause an increasingly largeburden in developed countries and in urban areas of middleincomecountries . Paras itic infections may induce allergicresponses in humans, particularly soil-transmitted helminth(STH) infections that are prevalent in childhood in developingcountries. Although soil-transmitted helminth infec tions havebeen associated with lower prevalence of allergen skin testreactivity, study outcomes remain inconclusive.Objective To analyze for an association between STH infectionsand skin prick test reactivity in children.Methods We conducted a cross-sectional study in August 2009among primary school students aged 7- 12 years, at SecanggangSubdistrict, Langkat District, North Sumatera Province. Sixtyeight children were recruited in this study consisted of 34 childrenwith STH infections and the other 34 children without any STHinfection. Soil-transmitted helminth infections were determinedby Kato-Katz stool examination s. All subjects underwent skinprick tests for seven allergens. Results were con sidered to bepositive if wheal diameters 2: 3 mm and negative when whealdiameters < 3 mm. Data was an alysed by Chi-square test.Results Stool examinations revealed that the most commoninfec tion was T. trichiura (18/34 subjects), followed by mixedinfections (T. trichiura and A lumbricoides; 12/34 subjects), andA. lumbricoides (4134 subjects). There was a significant associationbetween STH infections and negative skin prick test (P= 0.002).In addition, there were significant associations with negative skinprick tests for each helminth type: A. lumbricoides (P=0.001) ,T. trichiura (P=0.01) and mixed infection (P = 0.006). Severeinfection intensity was also significantly associated with negativeskin prick tests (P=0.031) .Conclusion Children with STH infections tend to have negativeskin prick test results.

scholarly journals Skin prick test is more useful than specific IgE for diagnosis of buckwheat allergy: A retrospective cross-sectional study

2018 ◽  
Vol 67 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Noriyuki Yanagida ◽  
Sakura Sato ◽  
Kyohei Takahashi ◽  
Ken-ichi Nagakura ◽  
Kiyotake Ogura ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
Specific Ige ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prick Test

Sensitization to inhaled allergens in Atopic children in Jordan Capital, Amman: a cross-sectional study.

2021 ◽  
Vol 17 ◽  
Author(s):  
Montaha AL-Iede ◽  
Abdallah Al-Ani ◽  
Baraa Mafrachi ◽  
Dana Al-Khulaifat ◽  
Kamal Hassan ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
Pediatric Population ◽  
Age Groups ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Prick Test ◽  
Group 2

Background: As the prevalence of allergic diseases is increasing all over the world, it is vital to identify the specific allergens which contribute to the development and persistence of such conditions. Objectives: This study aims to assess the prevalence of aeroallergen sensitization and, to evaluate the profile of skin prick test among atopic Jordanian children who are visiting Jordan University Hospital (JUH). Methods: A retrospective analysis of all Skin Prick Test (SPT) results of atopic children and adolescents aged (1.5-18 years) who were seen at the pediatrics clinics at JUH from January 2018 until December 2019. Results: Over two years, a total of 171 children (male: female ratio of 1.9) with a median age of 6.2 years (1.5-18) were subjected to SPT. One hundred and seven children (62.5%) were found to be sensitized to at least one of the ten aeroallergen extracts tested. The most common sensitizations were to olive pollen (45.6%), Mites Dermatophagoides Petronyssinus (42.0%), and Dog Dander (38.6%). The highest sensitization rate was among the age group 2-4 years (28.1%). The sensitization rates increased in conjunction with an increase in age in the first age groups (preschool and school-age groups). Conclusion: The study’s findings provide an understanding of the locally prevalent aeroallergens, yet a multi-center review would be more useful for creating an optimized SPT panel specific to the Jordanian pediatric population.

scholarly journals Leptin, ghrelin and calprotectin: inflammatory markers in childhood asthma?

2013 ◽  
Vol 8 ◽  
Author(s):  
Nazan Cobanoglu ◽  
Nilufer Galip ◽  
Ceyhun Dalkan ◽  
Nerin Nadir Bahceciler
Keyword(s):  
Skin Prick Test ◽  
Vital Capacity ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prick Test ◽  
Previous Diagnosis ◽  
Group 2 ◽  
Group 1

Background: Appetite-modulating hormones ghrelin and leptin might be relevant to asthma with their pro-inflammatory effects, and calprotectin has been recognized as a promising marker of inflammation. The purpose of this study was to explore whether asthma, atopy and lung functions has a relation with serum levels of leptin, ghrelin and calprotectin as inflammatory markers in children. Methods: A cross-sectional study was performed by searching the doctor diagnosed asthma through questionnaires filled in by parents who were phoned, and children were invited to supply fasting blood samples in order to measure serum levels of leptin, ghrelin and calprotectin, and to perform skin prick test and spirometry. Participants were divided into Group 1, children with previous diagnosis of asthma, and Group 2, children without previous diagnosis of asthma. Results: One thousand and two hundred questionnaires were distributed and 589 of them were returned filled in. Out of 74 children whose parents accepted to participate in the study, 23 were in Group 1 and 51 were in Group 2. There was no statistical difference in serum levels of leptin, ghrelin, calprotectin, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF) , forced expiratory flow between 25 and 75% of vital capacity (FEF25-75) values , and skin prick test results between the two groups (p values are 0.39, 0.72, 0.5, 0.17, 0.5, 0.27, 0.18, and 0.81 respectively). Conclusion: In this study the inflammation in asthmatic children could not be shown by using serum leptin, ghrelin and calprotectin levels and this is possibly due to the low number of children with ever asthma and equal skin prick test positivity in both groups. This study is the first study aimed to show the relation between serum calprotectin levels and inflammation in asthma. As this study was a cross-sectional study, further prospectively designed randomized controlled studies are necessary to show the association of these markers and inflammation in asthma.

scholarly journals Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e018010 ◽  
Author(s):  
Ji Eun Soh ◽  
Kyung-Moon Kim ◽  
Ji-Won Kwon ◽  
Hyung Young Kim ◽  
Ju-Hee Seo ◽  
...  
Keyword(s):  
Preschool Children ◽  
Lung Function ◽  
Airway Inflammation ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Airway Function ◽  
Recurrent Wheeze

BackgroundRelationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.ObjectiveTo investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.DesignObservational study, comparing forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and mid-forced expiratory flow (FEF25%–75%), dose–response slope (DRS), exhaled nitric oxide (eNO) and atopic sensitisation between children with recurrent wheeze and those without.SettingPopulation-based, cross-sectional study in Seoul and the Gyeonggi province of Korea conducted as a government-funded programme to perform standardised measurement of the prevalence of allergic diseases, and related factors, in preschool children.Participants900 children aged 4–6 years.Primary and secondary outcome measureseNO, FEV1/FVC, FEF25%–75%, DRS, atopic sensitisation and allergic diseases.MethodsChildren completed the modified International Study of Asthma and Allergies in Childhood questionnaire and underwent eNO assessments, spirometry, methacholine bronchial provocation tests and skin prick tests. Recurrent wheeze was defined as having a lifetime wheeze of more than three episodes, based on the questionnaire. The frequency of hospitalisation and emergency room visits was also obtained by means of the questionnaire. ‘Current’ wheeze was defined as having symptoms or treatments within the past 12 months.ResultsThe prevalence of recurrent wheeze was 13.4%. Children with recurrent wheeze showed a higher prevalence of lifetime or current allergic rhinitis (p=0.01 and p=0.002, respectively) and lifetime atopic dermatitis (p=0.007). Children with recurrent wheeze showed lower FEV1/FVC (p=0.033) and FEF25%–75%(p=0.004), and higher eNO levels (p=0.013) than those without recurrent wheeze. However, the DRS, prevalence of atopic sensitisation and serum IgE levels were not significantly different between the two groups.ConclusionsRecurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy.

scholarly journals Sensitization profile in patients with respiratory allergic diseases: differences between conventional and molecular diagnosis (a cross-sectional study)

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Guillermo Til-Pérez ◽  
Claudio Carnevale ◽  
Pedro Luis Sarría-Echegaray ◽  
Diego Arancibia-Tagle ◽  
Sendy Chugo-Gordillo ◽  
...  
Keyword(s):  
Molecular Diagnosis ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Atopy and Quality of Life in Pediatric Chronic Rhinosinusitis

2019 ◽  
Vol 33 (5) ◽  
pp. 586-590 ◽  
Author(s):  
Anamika Anamika ◽  
Arunabha Chakravarti ◽  
Raj Kumar
Keyword(s):  
Quality Of Life ◽  
Skin Prick Test ◽  
Chronic Rhinosinusitis ◽  
Cross Sectional Study ◽  
Endoscopic Examination ◽  
Positive Skin Prick Test ◽  
Cross Sectional ◽  
Positive Skin ◽  
Prick Test

Background Atopy has been suggested in the development of chronic rhinosinusitis (CRS), as allergic rhinitis (AR) is common coexisting disease in pediatric and adult patients with CRS. The contribution of AR to CRS is less clear till date. Objectives The objectives of this study were to determine atopic profile of children with CRS and impact of atopic status on disease severity and quality of life. Methods One hundred ten patients, aged between 7 and 18 years of age, diagnosed with CRS based on history, detailed clinical examination including nasal endoscopic examination were included in this cross-sectional study. Scoring of CRS was done according to Lund Mackay Endoscopic Appearance Score. Patients underwent skin prick test against 65 common aeroallergens (1:10 w/v, 50% glycerinated) for evidence of atopy. SN-5 Sinus and Nasal Quality of Life Survey was used to assess the quality of life in the study subjects. Results Positive skin prick test to at least one of the common aeroallergens was present in 58 (52.7%) patients. Most common aeroallergen sensitivity was seen with insects in 48 (43.6%) patients. Patients of CRS with atopy had higher mean Lund Mackay endoscopic score and SN-5 score than nonatopic patients which was statistically significant. Conclusion In conclusion, we recommend that testing for aeroallergen sensitivity and assessment of quality of life should be included in the protocol for diagnosis and management of pediatric patients with CRS. Early diagnosis and treatment of allergy may halt the progression of CRS and also the development of asthma and other allergic multimorbid disorders.

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