scholarly journals Preparation and Evaluation of Mangifera Indica Loaded Ethosomal Gel for Anti-Inflammatory Activity in Animal Model

2018 ◽  
Author(s):  
Sireesha Kalva ◽  
Keyword(s):  
Animal Model ◽  
Mangifera Indica ◽  
Inflammatory Activity ◽  
Anti Inflammatory ◽  
Preparation And Evaluation

Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet

2019 ◽  
Vol 10 (8) ◽  
pp. 4861-4867 ◽  
Author(s):  
Renata Celi Lopes Toledo ◽  
Larissa Froede Brito ◽  
Mônica Maria Magalhães Caetano ◽  
Vânia Mayumi Nakajima ◽  
Bárbara Pereira da Silva ◽  
...  
Keyword(s):  
Acute Treatment ◽  
Leaf Extract ◽  
Mangifera Indica ◽  
Cafeteria Diet ◽  
Inflammatory Activity ◽  
Liver Inflammation ◽  
Anti Inflammatory

This study investigates the acute anti-inflammatory activity of Mangifera indica L. leaf extract and mangiferin in the liver of rats fed a cafeteria diet.

scholarly journals Anti-Inflammatory Activity of Ethnic Vegetables Osonshak <i>(Spilanthes calva)</i> and Chikipung <i>(Rumex vesicarius)</i> in Animal Model

2021 ◽  
Vol 12 (04) ◽  
pp. 85-90
Author(s):  
Sadia Tabaasum ◽  
Sneha Sarawar ◽  
Sheikh Faisal Assadullah Mahadi ◽  
Sheikh Nazrul Islam
Keyword(s):  
Animal Model ◽  
Inflammatory Activity ◽  
Anti Inflammatory

scholarly journals Preparation and Evaluation of Herbal Anti-Inflammatory Gel

2021 ◽  
pp. 48-52
Author(s):  
Shrikant M. Madhekar ◽  
Ms. Amanpreetkaur Dumda ◽  
Mr. Pinjari Juned Shaikh Ismail ◽  
Mr. Baig Ubaid Quader Baig
Keyword(s):  
Health Care ◽  
Xanthan Gum ◽  
Skin Irritation ◽  
Herbal Medicines ◽  
Inflammatory Activity ◽  
Anti Inflammatory ◽  
Health And Healing ◽  
Gel Formulations ◽  
Preparation And Evaluation ◽  
Good Homogeneity

Herbal medicines is still the mainstay of about 75-80% of the world’s population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatibility with human body and lesser side effects. Herbal medicines consist of plant or its part to treat injuries, disease or illnesses and are used to prevent and treat diseases and ailments or to promote health and healing. It is a drug or preparation made from a plant or plants and used for any to such purpose. Herbal medicines are the oldest form of health care known to mankind. Gel formulations prepared with Carbopol 934, HPMC K 100 M and Xanthan gum showed good homogeneity, no skin irritation, good stability and anti-inflammatory activity. However, the Xanthan gum based gel proved to the formula of choice, since it showed the highest percentage of extrudability, good spreadability and rheological properties. Formulation F1 and F5 showed the best formulation with significant anti-inflammatory activity. Formulation 1 and F5 shows approximately equal anti-inflammatory activity.

scholarly journals The anti-inflammatory activity of standard aqueous stem bark extract of Mangifera indica L. as evident in inhibition of Group IA sPLA2

2016 ◽  
Vol 88 (1) ◽  
pp. 197-209 ◽  
Author(s):  
BHADRAPURA LAKKAPPA DHANANJAYA ◽  
SUDHARSHAN SHIVALINGAIAH
Keyword(s):  
Mangifera Indica ◽  
Direct Interaction ◽  
Pharmaceutical Formulations ◽  
Stem Bark ◽  
Inflammatory Activity ◽  
Bark Extract ◽  
Binding Studies ◽  
Edema Formation ◽  
Stem Bark Extract ◽  
Anti Inflammatory

ABSTRACT The standard aqueous stem bark extract is consumed as herbal drink and used in the pharmaceutical formulations to treat patients suffering from various disease conditions in Cuba. This study was carried out to evaluate the modulatory effect of standard aqueous bark extract of M. indica on Group IA sPLA2. M. indica extract, dose dependently inhibited the GIA sPLA2 (NN-XIa-PLA2) activity with an IC50 value 8.1 µg/ml. M. indica extract effectively inhibited the indirect hemolytic activity up to 98% at ~40 µg/ml concentration and at various concentrations (0-50 µg/ml), it dose dependently inhibited the edema formation. When examined as a function of increased substrate and calcium concentration, there was no relieve of inhibitory effect on the GIA sPLA2. Furthermore, the inhibition was irreversible as evidenced from binding studies. It is observed that the aqueous extract ofM. indica effectively inhibits sPLA2 and it is associated inflammatory activities, which substantiate their anti-inflammatory properties. The mode of inhibition could be due to direct interaction of components present in the extract, with sPLA2 enzyme. Further studies on understanding the principal constituents, responsible for the anti-inflammatory activity would be interesting to develop this into potent anti-inflammatory agent.

Mesenchymal stem/stromal cell-derived microparticles show anti-inflammatory activity in an animal model of ulcerative colitis

Cytotherapy ◽  
2014 ◽  
Vol 16 (4) ◽  
pp. S25
Author(s):  
A. Del Fattore ◽  
R. Luciano ◽  
A. Fierabracci ◽  
M. Muraca
Keyword(s):  
Ulcerative Colitis ◽  
Animal Model ◽  
Stromal Cell ◽  
Inflammatory Activity ◽  
Anti Inflammatory
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