Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: a nationwide population-based study

Although recent clinical studies have suggested that water intake enhances muscle mass, its impact on muscle strength remain unclear, especially in older adults. This cross-sectional, population-based study using a representative sample of Koreans investigated the relationship of water intake with hand grip strength (HGS) in 4443 older adults, including 2090 men aged ≥50 years and 2253 postmenopausal women. A digital grip strength dynamometer was used for HGS assessment. Low muscle strength was defined by the Korean-specific HGS cut-off value and adequate water intake was defined according to the Korean dietary reference intakes. In an unadjusted model, water intake was significantly higher in men and women without than with low muscle strength (both p < 0.001), but this difference disappeared after adjustment for confounding variables in both men (p = 0.050) and women (p = 0.245). Similarly, the correlation between water intake and HGS, the difference in HGS depending on adequate water intake status, and the risk of low muscle strength depending on water intake quartile were significant only in the unadjusted model. These data indicate that factors such as age, body size, and resistance exercise contribute to improvements in HGS in older adults, whereas water intake may not.

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Lack of Association Between Vitamin D and Hand Grip Strength in Asians: A Nationwide Population-Based Study

Calcified Tissue International ◽

10.1007/s00223-018-0480-7 ◽

2018 ◽

Vol 104 (2) ◽

pp. 152-159 ◽

Cited By ~ 2

Author(s):

Beom-Jun Kim ◽

Mi Kyung Kwak ◽

Seung Hun Lee ◽

Jung-Min Koh

Keyword(s):

Vitamin D ◽

Grip Strength ◽

Population Based ◽

Hand Grip Strength ◽

Population Based Study ◽

Hand Grip

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Lower hand grip strength in older adults with non-alcoholic fatty liver disease: a nationwide population-based study

Aging ◽

10.18632/aging.102068 ◽

2019 ◽

Vol 11 (13) ◽

pp. 4547-4560 ◽

Cited By ~ 3

Author(s):

Beom-Jun Kim ◽

Seong Hee Ahn ◽

Seung Hun Lee ◽

Seongbin Hong ◽

Mark W. Hamrick ◽

...

Keyword(s):

Older Adults ◽

Liver Disease ◽

Fatty Liver ◽

Grip Strength ◽

Fatty Liver Disease ◽

Population Based ◽

Population Based Study ◽

Alcoholic Fatty Liver ◽

Hand Grip ◽

Alcoholic Fatty Liver Disease

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Hand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study

International Journal of Chronic Obstructive Pulmonary Disease ◽

10.2147/copd.s114154 ◽

2016 ◽

Vol Volume 11 ◽

pp. 2527-2534 ◽

Cited By ~ 8

Author(s):

Viktor Johansson Strandkvist ◽

Helena Backman ◽

Jenny Roding ◽

Caroline Stridsman ◽

Anne Lindberg

Keyword(s):

Cohort Study ◽

Grip Strength ◽

Population Based ◽

Forced Expiratory Volume ◽

Hand Grip Strength ◽

Hand Grip

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Peer Review #2 of "Comparison of hand grip strength and upper limb pressure pain threshold between older adults with or without non-specific shoulder pain (v0.1)"

10.7287/peerj.2995v0.1/reviews/2 ◽

2017 ◽

Keyword(s):

Older Adults ◽

Peer Review ◽

Grip Strength ◽

Shoulder Pain ◽

Upper Limb ◽

Pain Threshold ◽

Pressure Pain Threshold ◽

Hand Grip Strength ◽

Pressure Pain ◽

Hand Grip

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Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study

Scandinavian Journal of Public Health ◽

10.1177/1403494818801628 ◽

2018 ◽

Vol 48 (4) ◽

pp. 436-441 ◽

Cited By ~ 3

Author(s):

Marcus E. Cöster ◽

Magnus Karlsson ◽

Claes Ohlsson ◽

Dan Mellström ◽

Mattias Lorentzon ◽

...

Keyword(s):

Grip Strength ◽

Osteoporotic Fractures ◽

The Elderly ◽

Population Based ◽

Hand Grip Strength ◽

Test Time ◽

Physical Test ◽

Walking Test ◽

Hand Grip ◽

Physical Tests

Aims: Falls are common in the elderly population, and fall-related injuries are a major health issue. We investigated the ability of simple physical tests to predict incident falls. Methods: The Swedish Osteoporotic Fractures in Men (MrOS) study includes 3014 population-based men aged 69–81 years at the start of the study. These men performed five different physical tests at baseline: right-hand grip strength, left-hand grip strength, timed stand test, 6 m walking test (time and steps) and narrow walking test. During the first study year, we asked participants to fill out questionnaires regarding falls 4, 8 and 12 months after baseline. A total of 2969 men completed at least one questionnaire and were included in this study. We used generalised estimating equations and logarithmic regression models to estimate odds ratios for fallers and recurrent fallers (more than one fall during the one-year examination period) in each quartile of men for each physical test. Results: The proportions of fallers and recurrent fallers were higher in the lowest quartile of the physical tests than in the other three quartiles combined for all physical tests. A reduction of one standard deviation in respective physical test resulted in a 13–21% higher risk of becoming a faller and a 13–31% higher risk of becoming a recurrent faller. Conclusions: Low results on simple physical tests is a risk factor for incident falls in elderly Swedish men and may facilitate identification of high-risk individuals suitable for fall-intervention programs.

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The Brain-Derived Neurotrophic Factor Functional Polymorphism and Hand Grip Strength Impact the Association between Brain-Derived Neurotrophic Factor Levels and Cognition in Older Adults in the United States

Biological Research For Nursing ◽

10.1177/10998004211065151 ◽

2022 ◽

pp. 109980042110651

Author(s):

Tingting Liu ◽

Hongjin Li ◽

Yvette P. Conley ◽

Brian A. Primack ◽

Jing Wang ◽

...

Keyword(s):

Older Adults ◽

Cognitive Function ◽

Cognitive Decline ◽

Grip Strength ◽

Mental Status ◽

Neurotrophic Factor ◽

Brain Derived Neurotrophic Factor ◽

Hand Grip Strength ◽

Hand Grip ◽

Serum Bdnf

Introduction Aging is associated with subtle cognitive decline in attention, memory, executive function, processing speed, and reasoning. Although lower brain-derived neurotrophic factor (BDNF) has been linked to cognitive decline among older adults, it is not known if the association differs among individuals with various BDNF Val66Met (rs6265) genotypes. In addition, it is not clear whether these associations vary by hand grip strength or physical activity (PA). Methods A total of 2904 older adults were included in this study using data from the Health and Retirement Study. Associations between serum BDNF and measures of cognitive function were evaluated using multivariable linear regression models stratified by Met allele status. PA and hand grip strength were added to the model to evaluate whether including these variables altered associations between serum BDNF and cognition. Results Mean age was 71.4 years old, and mean body mass index was 28.3 kg/m2. Serum BDNF levels were positively associated with higher total cognitive score (beta = 0.34, p = .07), mental status (beta = 0.16, p = .07), and word recall (beta = 0.22, p =.04) among Met carriers, while serum BDNF levels were negatively associated with mental status (beta = −0.09, p = .07) among non-Met carriers. Furthermore, associations changed when hand grip strength was added to the model but not when PA was added to the model. Conclusions The BDNF Val66Met variant may moderate the association between serum BDNF levels and cognitive function in older adults. Furthermore, such associations differ according to hand grip strength but not PA.

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