scholarly journals Normal-sized basal ganglia perivascular space related to motor phenotype in Parkinson freezers

Aging ◽  
2021 ◽  
Author(s):  
Wen Lv ◽  
Yumei Yue ◽  
Ting Shen ◽  
Xingyue Hu ◽  
Lili Chen ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Perivascular Space ◽  
Motor Phenotype

scholarly journals Motor phenotype and magnetic resonance measures of basal ganglia iron levels in Parkinson's disease

2013 ◽  
Vol 19 (12) ◽  
pp. 1136-1142 ◽  
Author(s):  
Nico Bunzeck ◽  
Victoria Singh-Curry ◽  
Cindy Eckart ◽  
Nikolaus Weiskopf ◽  
Richard J. Perry ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Magnetic Resonance ◽  
Motor Phenotype

scholarly journals Relationship between Contrast Enhancement of the Perivascular Space in the Basal Ganglia and Endolymphatic Volume Ratio

2018 ◽  
Vol 17 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Toshio Ohashi ◽  
Shinji Naganawa ◽  
Toshio Katagiri ◽  
Kayao Kuno
Keyword(s):  
Basal Ganglia ◽  
Contrast Enhancement ◽  
Volume Ratio ◽  
Perivascular Space

Abstract WP211: The Association Between Arterial Stiffness and Perivascular Space Topography in Stroke Patients

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Jae-Han Bae ◽  
Kwang-Yeol Park ◽  
Jeong-Min Kim ◽  
Moo-Suk Park
Keyword(s):  
Basal Ganglia ◽  
Arterial Stiffness ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Laboratory Data ◽  
Multivariate Logistic Regression Analysis ◽  
Perivascular Space ◽  
University Hospital ◽  
Centrum Semiovale ◽  
High Degree

Background: Arterial stiffness aggravation is known to increase cerebral small vessel disease burden. We investigated the association between brachial-ankle pulse wave velocity (baPWV) and the topography of MRI visible perivascular space in acute stroke population. Method: We analyzed clinical and laboratory data of acute ischemic stroke or transient ischemic attack patients who had been admitted to Chung-Ang University Hospital within 7 days after symptom onset between January 1st 2014 and May 31th 2015. We included those patients who underwent both brain MR imaging including T2 weighted sequence and baPWV. The topography of perivascular space was examined in basal ganglia and centrum semiovale level with validating scale (score 0-4), and dichotomized as low (score3). Result: A total of 481 patients were included (mean age 68.2±12.3, 44.7% male). When the distribution of baPWV were divided into quartile, the proportions of high PVS in basal ganglia was 10%, 20%, 40% and 40%, respectively. The proportion of high PVS in centrum semiovale was 20%, 40%, 36%, and 49%, respectively. Multivariate logistic regression analysis revealed that the high degree of basal ganglia PVS was associated with baPWV>2255cm/s (odds ratio 1.7, confidence interval 1.0-2.7, p=0.048) after adjusting age>70 years, hypertension, current smoking status and previous stroke history. The high degree of centrum semiovale PVS showed marginal association with baPWV>2255cm/s (odds ratio=1.4, confidence interval 0.9-2.3, p=0.137) after adjusting age>70 years and hypertension. Conclusion: Our pilot study suggests potential pathophysiological association between arterial stiffness and PVS topography.

scholarly journals Insulin Resistance Is Independently Associated With Enlarged Perivascular Space in the Basal Ganglia in Nondiabetic Healthy Elderly Population

2020 ◽  
Vol 35 ◽  
pp. 153331752091212
Author(s):  
Danhong Wu ◽  
Xiaoli Yang ◽  
Ping Zhong ◽  
Xiaofei Ye ◽  
Chen Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Basal Ganglia ◽  
Elderly Population ◽  
Resistance Index ◽  
Perivascular Space ◽  
Model Assessment ◽  
Logistic Analysis ◽  
Healthy Elderly ◽  
Level Scale

Objectives: To investigate the association between insulin resistance (IR) and enlarged perivascular space (EPVS) in the basal gangliain nondiabetic healthy elderly population. Methods: A total of 235 nondiabetic healthy elderly population were recruited. A 3-level scale was used to evaluate the burden of EPVSs. The homeostasis model assessment–estimated insulin resistance index (HOMA-IR) was used for IR estimation. Correlation between IR and severity of EPVS was assessed using the regression model after adjusting demographics and cardiovascular risk factors. Results: The top quartile of HOMA-IR was 2.52, and 25.11% of patients showed IR. The proportion of patients with IR was higher in the moderate to severe EPVS group than in the mild group (36.51% vs 20.93%, P = .015). In multivariate logistic analysis, IR was positively correlated with the moderate to severe EPVS (adjusted odds ratio: 3.532, 95% confidence interval: 1.633-7.636, P = .001) after adjusting classical risk factors. Conclusions: Insulin resistance was independently correlated with EPVS in the basal ganglia in nondiabetic healthy elderly population.

Review of The Basal Ganglia II: Structure and Function--Current Concepts.

1988 ◽  
Vol 33 (11) ◽  
pp. 1008-1008
Author(s):  
No authorship indicated
Keyword(s):  
Basal Ganglia ◽  
Structure And Function ◽  
And Function

An fMRI Study of Arithmetic Training: Different Activation Patterns of Basal Ganglia Due to Differences in Training Procedures

2011 ◽  
Author(s):  
Arava Y. Kallai ◽  
Christian D. Schunn ◽  
Julie A. Fiez
Keyword(s):  
Basal Ganglia ◽  
Activation Patterns ◽  
Fmri Study

Righting a wrong: Dissociable effects of dorsomedial frontal and basal ganglia damage on error inhibition and correction

2013 ◽  
Author(s):  
Eldad Yitzhak Hochman ◽  
Seqian Wang ◽  
Theodor E. Milner ◽  
Lesley K. Fellows
Keyword(s):  
Basal Ganglia

Objective motor phenotype assessment of gait and posture in pre-manifest and symptomatic Huntington's disease

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
H Beckmann ◽  
S Rumpf ◽  
N Bechtel ◽  
HW Lange ◽  
C Saft ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Motor Phenotype
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