One of the major challenges of ANLP research is the constant balancing act between the need for large samples, and the excessive time and monetary resources necessary for acquiring those samples. Amazon’s Mechanical Turk (MTurk) is a web-based data collection tool that has become a premier resource for researchers who are interested in optimizing their sample sizes and minimizing costs. Due to its supportive infrastructure, diverse participant pool, quality of data, and time and cost efficiency, MTurk seems particularly suitable for ANLP researchers who are interested in gathering large, high quality corpora in relatively short time frames. In this chapter, the authors first provide a broad description of the MTurk interface. Next, they describe the steps for acquiring IRB approval of MTurk experiments, designing experiments using the MTurk dashboard, and managing data. Finally, the chapter concludes by discussing the potential benefits and limitations of using MTurk for ANLP experimentation.