scholarly journals Hyperthyroidism with Struma Ovarii

2014 ◽  
Vol 3 (1) ◽  
pp. 344
Author(s):  
Sarbhjit Kaur ◽  
Vijay Kumar Bodal ◽  
Manjit Singh Bal ◽  
Ranjeev Bhagat ◽  
Nishit Gupta ◽  
...  
Keyword(s):  
Malignant Lymphoma ◽  
Papillary Carcinoma ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Ovarian Neoplasm ◽  
Ovarian Tumors ◽  
Rare Tumor ◽  
Struma Ovarii ◽  
Ovarian Mass ◽  
Nodular Hyperplasia

<p>Struma ovarii or monodermal teratoma, is a specialized ovarian neoplasm composed entirely of mature thyroid tissue. It is a relatively rare tumor which comprises 1% of all ovarian tumors and 2.7% of all dermoid tumors. Its colour and consistency is like that of a thyroid tissue. The tissue may show any of the pathologic changes seen in a normally placed gland, including diffuse or nodular hyperplasia, thyroiditis, papillary carcinoma, follicular carcinoma and malignant lymphoma.</p><p>We reported a case of hyperthyroidism with struma ovarii. A 70 year old female was operated for ovarian mass. The sign and symptoms subside after operation.</p>

THYROID TYPE CARCINOMA ARISING IN STRUMA OVARII. SIX CLINICAL CASES AND REVIEW

2018 ◽  
Vol 64 (6) ◽  
pp. 708-715
Author(s):  
Natalya Severskaya ◽  
Andrey Rodichev ◽  
Aleksey Ilin ◽  
Dmitriy Semin ◽  
Pavel Isaev ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Clinical Course ◽  
Case Reports ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Complete Response ◽  
Pelvic Surgery ◽  
Ovarian Teratoma ◽  
Struma Ovarii

Struma ovarii is a rare variant of the mature ovarian teratoma composed of more than 50% thyroid tissue. Thyroid type carcinoma can occur in 5% of struma ovarii. Given the rarity of this pathology, as well as the different clinical course, approaches to the treatment of this disease are controversial. The proposed approaches to treatment vary from ovarian resection to total hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. We present here 6 case reports of thyroid type carcinoma in struma ovarii and outcome of patients treated in our clinic. All patients had pelvic surgery of different extent, followed by thyroidectomy and radioiodine therapy. The incidence of metastasis is 67% (4/6), 2 - intraperitoneal metas-tases, 2 - bone metastases. Among patients with metastases, 2 have reached a complete response, one with a good response continues treatment, one had progression. The follow-up period is 1 to 15 years (median 4 years). One patient with follicular carcinoma died of progression 8 years after diagnosis. The remaining patients are alive.

Struma ovarii-A rare entity

2021 ◽  
Vol 11 (1) ◽  
pp. 1898-1901
Author(s):  
Moushami Singh ◽  
Raghu Ram Bhandary ◽  
Jitendra Pariyar ◽  
Swechha Maskey ◽  
Hari Prasad Dhakal
Keyword(s):  
Benign Tumor ◽  
Histopathological Examination ◽  
Frozen Section ◽  
Abdominal Mass ◽  
Thyroid Tissue ◽  
Blood Parameters ◽  
Immature Teratoma ◽  
Rare Entity ◽  
Struma Ovarii ◽  
Ovarian Mass

Struma ovarii, also known as goiter of the ovary is a rare disease.1 Considering the rarity of this tumor and constrained literature in Nepal’s context, we hereby present a case of a 46-year-old female, asymptomatic, with normal blood parameters who presented with an abdominal mass. She was suspected of malignant ovarian mass on an ultrasonogram. Intraoperative frozen section examination revealed a benign tumor suggestive of dermal tumor versus struma ovarii. Postoperatively, histopathological examination was performed to assess the percentage of thyroid tissue and a diagnosis of benign struma ovarii was made which was confirmed by thyroglobulin positivity on immunohistochemistry. No features of immature teratoma and malignancy were identified.

Malignant Clinical Course of Histologically Benign Ovarian Struma: case report and literature review

2021 ◽  
Author(s):  
Aleksandra Asaturova ◽  
A. Magnaeva ◽  
A. Tregubova ◽  
V. Kometova ◽  
E. Karamurzin ◽  
...  
Keyword(s):  
Case Report ◽  
Ovarian Tumor ◽  
Clinical Course ◽  
Mature Teratoma ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Struma Ovarii ◽  
Diagnostic Challenge ◽  
Laboratory Findings ◽  
Metastatic Lesions

Abstract BackgroundStruma ovarii is a variant of monodermal teratoma, consisting of morphologically benign, atypical, or frankly malignant thyroid tissue. Morphologic features may or may not correlate with biologic behavior. Albeit this case report is not unique, ovarian tumor developed with peritoneal dissemination and bone metastasis, which is highly unlikely clinical complication. Additionally, we summarized previously cases of struma ovarii with an emphasis on correlation between morphological appearances, clinical course and providing treatment. Case presentationWe present the 38-year-old patient who was hospitalized for ovarian tumor. The diagnostic laparoscopy revealed lesions of peritoneum, sigmoid serosa and omentum and left ovarian mass. We diagnosed left ovarian mature teratoma without struma tissue and metastatic lesions with struma morphology which can be related to her history of left ovarian struma in 2016. Taking into account the metastatic lesions revealed in 2020, the tumor removed in 2016 was assessed as highly differentiated follicular carcinoma arising in struma ovarii. ConclusionsPrediction of biologic behavior of struma ovarii is still to be to diagnostic challenge, therefore multidisciplinary approach including clinical a n d laboratory findings, radiologic details and histopathological features is required. Providing additional data, the present case report contributes to expending the knowledge of these peculiar neoplasms.

scholarly journals A case benign struma ovarii

2021 ◽  
Vol 10 (3) ◽  
pp. 1224
Author(s):  
P. G. Paul ◽  
Anjana Annal ◽  
K. Anusha Chowdary ◽  
George Paul ◽  
Manali Shilotri
Keyword(s):  
Adnexal Mass ◽  
Thyroid Tissue ◽  
Clinical Manifestations ◽  
Benign Disease ◽  
Definitive Diagnosis ◽  
Ovarian Tumors ◽  
Struma Ovarii ◽  
Standard Line ◽  
Imaging Characteristics ◽  
The Right

Struma ovarii is a rare ovarian tumor and a monodermal variant of dermoid tumors of the ovary in which thyroid tissue components constitute more than 50% of the mass. Struma ovarii accounts for 0.5–1.0% of all ovarian tumors and 2-5% of ovarian teratomas. Most cases are benign, but malignant transformation is found in a small percentage. It usually presents as a unilateral adnexal mass at fifth and sixth decades of life, with symptoms like other ovarian tumors. The definitive diagnosis is made by histological examination. Adnexectomy remains the standard line of treatment for benign disease. A 41-year-old lady presented with pain in abdomen for 3 months. On ultrasonography and MRI, a multiloculated solid cystic lesion of 7×6 cm with internal echoes was found in the right adnexa. Laparoscopic right adnexectomy was performed. Histopathology was consistent with struma ovarii. Due to its vague clinical manifestations and diverse imaging characteristics, pre-operative diagnosis is challenging. 

Struma Ovarii : A Rare Monodermal Teratoma

JMS SKIMS ◽  
2017 ◽  
Vol 20 (1) ◽  
pp. 41-43
Author(s):  
Abdul Rasheed Rather ◽  
Shazia Bashir ◽  
Ather Hafiz Khan ◽  
Ashfaq Ul Hassan ◽  
Mohsin Ul Rasool ◽  
...  
Keyword(s):  
Ct Scan ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Ovarian Tumors ◽  
Rare Tumor ◽  
Struma Ovarii ◽  
Lower Abdomen ◽  
Loss Of Appetite ◽  
Adnexal Lesion

Struma ovarii is a rare tumor of ovary which accounts for 1% of all ovarian tumors and 3% 0f all dermoid tumors. It belongs to the group of monodermal teratomas. We present a case of struma ovarii in a 55 year old women who presented with symptoms of pain in lower abdomen and loss of appetite for the last one month. Radiological investigations including USG, CT scan and MRI revealed a complex right adnexal lesion. Final diagnosis of struma ovarii was made on histopathological examination which revealed colloid filled thyroid follicles lined by cuboidal epithelium. JMS 2017; 20(1):41-43

scholarly journals SUN-481 A Coexisting Primary Papillary Thyroid Carcinoma in a Case of Malignant Struma Ovarii with Follicular Thyroid Carcinoma: 2 Types of Thyroid Cancer in the Same Patient

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Ghada Elshimy ◽  
Richa Bhattarai ◽  
Kelvin Tran ◽  
Ricardo Rafael Correa
Keyword(s):  
Thyroid Carcinoma ◽  
Total Thyroidectomy ◽  
Follicular Thyroid Carcinoma ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Good Prognosis ◽  
Struma Ovarii ◽  
Malignant Struma Ovarii ◽  
Lymph Node Sampling ◽  
Aortic Lymph Node

Abstract Introduction: Struma ovarii is a rare monodermal variant of ovarian teratoma diagnosed when thyroid tissue is more than 50% of the overall tissue. It represents only 1% of all ovarian tumors. The vast majority of struma ovarii are benign (95%); however, malignant tumors have been reported in a small percentage of cases. The most common type is papillary carcinoma(PTC), followed by typical follicular carcinoma found in the pathology after surgical oophorectomy. We report a case of malignant struma ovarii with follicular carcinoma in the setting of additional micro PTC found after total thyroidectomy. Case report: A 48-year-old female presented with right-sided pelvic pain and a mobile pelvic mass. Pelvic MRI showed noted a large complex solid mass with cystic components in the right adnexa. It measured 7.7 x 8.4 x 6.7 cm. Subsequently, the patient underwent a robotic hysterectomy, bilateral salpingo-oophorectomy (TAHBSO), bilateral pelvic and para-aortic lymph node sampling, omentectomy and resection of nodules. Final pathology noted an ovary with struma ovarii with well-differentiated follicular carcinoma, peritoneal nodules containing thyroid tissue and benign lymph nodes. Subsequently, iodine 123 SPECT CT showed physiologic uptake in the thyroid with increased uptake in the pelvis, right perirectal region indicating residual thyroid tissue. The patient underwent total thyroidectomy with radioactive ablation with I131 (154.7 mCi). Pathology detected incidental 0.5mm micro PTC and it was classified as staged pT1aN. 6 months postoperatively, thyroglobulin (Tg) and Tg antibodies were undetectable with no abnormalities found on repeat whole-body scans. The patient has been following up with no new issues for the past 5 years indicating a good prognosis with low risk of recurrence. Discussion and Conclusion: In the literature, Struma ovarii containing thyroid-type carcinoma and papillary or follicular thyroid carcinoma metastasizing to the ovary has been documented. The standard treatment of a patient with malignant struma ovarii is TAHBSO and complete surgical staging, including peritoneal washings for cytology, pelvic and para-aortic lymph node sampling, and omentectomy. In cases with the residual malignant disease after surgery, total thyroidectomy and radioactive ablation are recommended. Our case is a unique case given the presence of 2 different thyroid carcinoma in the same patient. In addition, our patient had multiple risk factors for recurrence including large lesions&gt;4 cm, extra ovarian extension, and the coexisting synchronous primary thyroid cancer, however, she had a good prognosis with no recurrence during the 5 years follow up period.

scholarly journals Papillary Thyroid Cancer in a Struma Ovarii in a 17-Year-Old Nulliparous Patient: A Case Report

Diagnostics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 45 ◽  
Author(s):  
Agnieszka Gonet ◽  
Rafał Ślusarczyk ◽  
Danuta Gąsior-Perczak ◽  
Artur Kowalik ◽  
Janusz Kopczyński ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Carcinoma ◽  
Papillary Thyroid Cancer ◽  
Histopathological Examination ◽  
Thyroid Tissue ◽  
Histopathological Diagnosis ◽  
Struma Ovarii ◽  
Papillary Thyroid ◽  
Preoperative Serum ◽  
Therapeutic Decisions

Introduction: Struma ovarii accounts for 2% of mature teratomas. Struma ovarii is diagnosed when thyroid tissue accounts for >50% of the teratoma. Malignant transformation is rare, occurring in <5% of struma ovarii cases. Case presentation: A 17-year-old patient was diagnosed with papillary thyroid cancer in struma ovarii. The patient exhibited menstrual disorders. Abdominal and pelvic CT revealed a 17 cm mass in the left adnexa. Laparoscopic removal of the left adnexa with enucleation of right ovarian cysts was performed. Histopathological diagnosis was a follicular variant papillary carcinoma measuring 23 mm in diameter. Immunohistochemical positive expression of CK19, TTF-1, and thyroglobulin (Tg) confirmed the diagnosis. Molecular analysis detected the BRAF K601E mutation in ovarian tumor tissues. Preoperative serum Tg concentration was >300 ng/mL, which decreased to 38.2 ng/mL after gynecological surgery with undetectable anti-Tg antibodies. The patient underwent total thyroidectomy with no cancer detected on histopathological examination. The patient was treated with I-131 and showed no recurrence 4 years after the diagnosis. Conclusions: Malignant struma ovarii is diagnosed by surgery. Because papillary carcinoma in struma ovarii is rare and there are no guidelines regarding the management of this type of cancer, therapeutic decisions should be made individually based on clinical and pathological data.

Occurrence of struma ovarii among women operated for ovarian teratoma

2011 ◽  
Vol 152 (24) ◽  
pp. 964-966
Author(s):  
Péter Sámuel Nagy ◽  
Csaba Vass ◽  
Zoltán Tóth
Keyword(s):  
Tumor Size ◽  
Clinical Symptoms ◽  
Thyroid Tissue ◽  
Morphological Characteristics ◽  
Ovarian Teratoma ◽  
Rare Tumor ◽  
Struma Ovarii ◽  
Hormonal Activity ◽  
Diagnostic Efficacy ◽  
Main Symptom

Ovarian monodermal teratoma containing thyroid tissue is a rare tumor. Authors reviewed the records of 94 patients operated for ovarian teratoma in their department between 1986 and 2002, of which 3 patients proved to have struma ovarii. They found that the 3 patients had highly variable clinical symptoms and morphological characteristics including tumor size, pain as main symptom, and the presence or absence of ascites and hormonal activity. It is concluded that struma ovarii appears to be poorly diagnosed, but an extensive histological examination may increase the diagnostic efficacy. Orv. Hetil., 2011, 152, 964–966.

scholarly journals Cystic struma ovarii: a rare presentation of an infrequent tumor

2000 ◽  
Vol 118 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Rita Barbosa de Carvalho ◽  
Maria Letícia Cintra ◽  
Patrícia Sabino de Matos ◽  
Paulo Sérgio Bueno de Campos
Keyword(s):  
Case Report ◽  
Diagnostic Criteria ◽  
Microscopic Examination ◽  
Thyroid Tissue ◽  
Ovarian Tumors ◽  
Epithelial Lining ◽  
Struma Ovarii ◽  
Rare Presentation ◽  
Rare Neoplasm ◽  
Diagnostic Problems

CONTEXT: Struma ovarii, a rare neoplasm, is a monophyletic teratoma composed of thyroid tissue. It is generally considered to account for less than 5% of mature teratomas. CASE REPORT: A diagnosis of struma ovarii may be the source of many diagnostic problems. It may be cystic and microscopic examination may only reveal a few typical thyroid follicles, resulting in confusion with other cystic ovarian tumors. Extensive sampling should be undertaken and immunohistochemistry may be decisive in establishing the thyroid nature of the epithelial lining. The authors report two cases of cystic struma ovarii, and discuss diagnostic criteria and the limitations of frozen biopsies in these tumors.

scholarly journals Thyroid Carcinoma on the Side of the Absent Lobe in a Patient with Thyroid Hemiagenesis

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Hiroki Sato ◽  
Kiyoaki Tsukahara ◽  
Ray Motohashi ◽  
Midori Wakiya ◽  
Hiromi Serizawa ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Papillary Carcinoma ◽  
Thyroid Tissue ◽  
Needle Aspiration ◽  
Left Lobe ◽  
Thyroid Hemiagenesis ◽  
Poorly Differentiated ◽  
Node Metastases ◽  
Right Lobe ◽  
The Right

Background. Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe. Methods and Results. We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma. Conclusions. All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.

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