Eye Loss Due to Disseminated Molluscum Contagiosum Skin Infection Involving the Eyelids in an Immune Competent Child

Background: Molluscum contagiosum is a common viral skin infection. Unusual presentations of this condition among immunocompetent individuals have rarely been reported. Objective: To highlight atypical clinical presentations of molluscum contagiosum in immunocompetent individuals. Methods and Results: An analysis of all cases of molluscum contagiosum with unusual presentation seen over a period of 2 years in the Farwaniya Department of Dermatology was conducted. Four patients (two males, two females), aged 13 to 35 years, with atypical molluscum contagiosum were encountered. Diagnosis was confirmed histopathologically. All of them were healthy, immunocompetent individuals without any underlying skin condition, except one who had preceding hand dermatitis. Clinical clues that could be helpful in making a diagnosis of molluscum contagiosum with an atypical presentation were looked for. Conclusion: A histopathologic examination may be necessary to make the diagnosis.

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Filaggrin mutations and Molluscum contagiosum skin infection in patients with atopic dermatitis

Annals of Allergy Asthma & Immunology ◽

10.1016/j.anai.2017.07.019 ◽

2017 ◽

Vol 119 (5) ◽

pp. 446-451 ◽

Cited By ~ 8

Author(s):

Sara Manti ◽

Maria Amorini ◽

Caterina Cuppari ◽

Annamaria Salpietro ◽

Francesca Porcino ◽

...

Keyword(s):

Atopic Dermatitis ◽

Skin Infection ◽

Molluscum Contagiosum

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Different Dermoscopic Aspects of Molluscum Contagiosum in the Same Patient: Case Report

Asploro Journal of Biomedical and Clinical Case Reports ◽

10.36502/2020/asjbccr.6199 ◽

2020 ◽

Vol 3 (2) ◽

pp. 128-131

Author(s):

Ziani J ◽

Chaoui R ◽

Oukarfi S ◽

Bennani M ◽

Elloudi S ◽

...

Keyword(s):

Case Report ◽

Skin Infection ◽

Skin Lesions ◽

Molluscum Contagiosum ◽

Epidermal Keratinocytes ◽

Patient Case ◽

Smallpox Virus ◽

Non Invasive ◽

Mucous Membranes ◽

Intracytoplasmic Inclusions

Molluscum contagiosum (MC) presents by skin lesions secondary to a viral skin infection at the expense of epidermal keratinocytes having appearances with specific intracytoplasmic inclusions caused by the smallpox virus. It is a frequent pathology that affects the skin and mucous membranes. The diagnosis of CD is easy, but when clinical features lack atypical lesions, it can hinder the diagnosis of CD. It is then that there is a need for early and easy diagnosis of CD by the ticket of the dermoscopy which is a non-invasive diagnostic tool that allows visualizing the different dermoscopic aspects that we describe through the same observation.

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Chemotherapy with paclitaxel for recalcitrant molluscum contagiosum in an HIV-infected patient

BMJ Case Reports ◽

10.1136/bcr-2020-240776 ◽

2021 ◽

Vol 14 (6) ◽

pp. e240776

Author(s):

Shannon Ugarte ◽

Sino Mehrmal ◽

Kevin Knopf

Keyword(s):

Skin Infection ◽

Social Stigma ◽

Molluscum Contagiosum ◽

Treatment Modalities ◽

Sexually Active ◽

Multiple Treatment ◽

The Social ◽

History Of ◽

Active Adults ◽

Cd4 T Cell Count

Molluscum contagiosum (MC) is a viral skin infection seen in children, sexually active adults and immunocompromised populations. It is usually a self-limiting illness that typically spontaneously resolves without therapeutic intervention. However, when the papules are extensive or refractory causing complications or aesthetic issues, multiple treatment modalities exist to relieve symptoms, limit spread and decrease the social stigma associated with visible lesions. Treatment is especially important in HIV/AIDS infected populations, where prevalence is estimated between 5% and 18% and susceptibility to larger, widespread and recalcitrant lesions involving atypical distributions is more common. We evaluated a 38-year-old woman with a history of AIDS (CD4+ T cell count <25 cells/µL) and poor adherence with antiretroviral therapy who presented with a 9-month history of persistent, progressively worsening facial and truncal umbilicated papules consistent with recalcitrant MC refractory to cidofovir injections. She was successfully treated with paclitaxel with complete resolution of the lesions after four cycles without adverse effects.

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