scholarly journals Electric Field Distribution Analysis of Blood Cancer as a Potential Blood Cancer Therapy

2021 ◽  
Vol 22 (2) ◽  
pp. 127
Author(s):  
Miftakhul Firdhaus ◽  
Ulya Farahdina ◽  
Vinda Zakiyatuz Zulfa ◽  
Endarko Endarko ◽  
Agus Rubiyanto ◽  
...  

Blood cancer causes a significant increase in the concentration of Leukocytes, which can be broken down through dielectrophoresis and electrochemical procedures. Therefore, the electric field plays an important role in the migration of leukocytes to high voltage areas. This is because different electrode arrangements produce varying electric field distributions. Furthermore, this study applied finite element methods to generate electric fields when electrodes with an AC voltage were applied to blood placed in a chamber. Therefore, in this study, variations of mediums and electrode arrangements were investigated, which led to the recommendation of 3 models. The objective was to investigate electrode arrangements that produce optimal electric field distribution for the three models to exhibit a booster of electric field distribution. The maximum electric field is generated close to the electrode (Z=2 mm and Z=92 mm) for any material (i.e. normal blood, B lymphocyte, and T lymphocyte) with values of 22.6 V/m and 23.47 V/m, 22.85 V/m and 22.97 V/m, and 24.88 V/m and 25.01 V/m. Based on principle, lymphocytes in the blood result in positive dielectrophoresis, since they migrate to a higher electric field close to the electrode, with enough input voltage to turn the electrochemical process on the leukocytes into electric current. Furthermore, this study provides new perspectives and ideas, which have not been revealed in previous studies on blood cancer therapy using the electric field of Ag electrode in blood cancer distribution.Keywords: blood cancer, dielectrophoresis, electric field, voltage, electrochemical, and cancer therapy.

Author(s):  
N. Rouger

Purpose – Scientists and engineers have been solving Poisson’s equation in PN junctions following two approaches: analytical solving or numerical methods. Although several efforts have been accomplished to offer accurate and fast analyses of the electric field distribution as a function of voltage bias and doping profiles, so far none achieved an analytic or semi-analytic solution to describe neither a double diffused PN junction nor a general case for any doping profile. The paper aims to discuss these issues. Design/methodology/approach – In this work, a double Gaussian doping distribution is first considered. However, such a doping profile leads to an implicit problem where Poisson’s equation cannot be solved analytically. A method is introduced and successfully applied, and compared to a finite element analysis. The approach is then generalized, where any doping profile can be considered. 2D and 3D extensions are also presented, when symmetries occur for the doping profile. Findings – These results and the approach here presented offer an efficient and accurate alternative to numerical methods for the modeling and simulation of mathematical equations arising in physics of semiconductor devices. Research limitations/implications – A general 3D extension in the case where no symmetry exists can be considered for further developments. Practical implications – The paper strongly simplify and ease the optimization and design of any PN junction. Originality/value – This paper provides a novel method for electric field distribution analysis.


2012 ◽  
Vol 229-231 ◽  
pp. 807-810
Author(s):  
Li Zhang ◽  
Qing Min Li ◽  
Li Na Zhang ◽  
Yu Di Cong

±1000kV DC wall bushing under planning is a complex insulation system which bears the effects imposed by different working conditions. The electric field distribution is concentrated at the bushing outlet terminal, which might result in breakdown discharge especially when short-time abrupt conditions such as polarity reversal occur. In this paper, the finite element method is utilized to analyze electric field distribution and potential distribution of wall bushing during polarity reversal. Electric field distribution and potential distribution at the moment of polarity reversal are obtained, which provides value reference for the study of polarity reversal process.


2011 ◽  
Vol 130-134 ◽  
pp. 1413-1417
Author(s):  
You Hua Gao ◽  
Guo Wei Liu ◽  
Yan Bin Li ◽  
You Feng Gao

Numerical calculation model with compound insulation of transient electric field is given. The insulation is more prominent due to complication for voltage applied on valve side winding of the converter transformer. So the simplied structure for electric calculation on the valve side winding of the converter transformer is established. The electric field distribution characteristics on the valve side winding of the converter transformer is analyzed and electric fields in different resistivity and permittivity are calculated under AC high voltage, DC high voltage, AC superimposed DC voltage, polarity reversal voltage. The maximum electric field intensity is calculated and analyzed under kinds of high voltage. Some important influence factors for electric field distribution are also discussed in this paper.


2015 ◽  
Vol 25 (3) ◽  
pp. 1-4 ◽  
Author(s):  
Jaeun Yoo ◽  
Woo-Ju Shin ◽  
Young-Hee Han ◽  
BangWook Lee ◽  
Hey-Rim Kim ◽  
...  

2021 ◽  
Vol 1816 (1) ◽  
pp. 012046
Author(s):  
U Farahdina ◽  
V Z Zulfa ◽  
M Firdhaus ◽  
E Endarko ◽  
A Rubiyanto ◽  
...  

Author(s):  
Gunnar Håkonseth ◽  
Erling Ildstad

Layered paper–oil insulation is used in several types of HVDC equipment. In order to better understand breakdown mechanisms and optimize the design, it is important to understand the electric field distribution in the insulation. In the present work, a test object with such insulation has been modeled as a series connection of oil and impregnated paper. The permittivity, conductivity, and the dielectric response function has been measured for impregnated paper and oil separately and used as parameters in a dielectric response model for the layered insulation system. A system of differential equations has been established describing the voltages across each material, i.e. across each layer of the test object. These equations have been solved considering a DC step voltage across the whole test object. Based on this, the time-dependent electric field in each material as well as the time-dependent polarization current density in the test object have been calculated. The calculated polarization current density was found to agree well with the measured polarization current density of the test object. This indicates that application of dielectric response theory gives a good estimate of the time-dependent electric field distribution in layered insulation systems. The results show that 90 % of the change from initial values to steady-state values for the electric fields has occurred within the first 35 minutes after the voltage step. This applies to the electric fields in both of the materials of the examined test object at a temperature of 323 K.


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