scholarly journals Methodology for assessing the degree of moisture ingress into the insulation of traction electric motors of diesel locomotives

2021 ◽  
Vol 2021 (4) ◽  
pp. 47-56
Author(s):  
Vladimir V. GRACHEV ◽  
◽  
Aleksandr V. GRISHCHENKO ◽  
Marina A. SCHREIBER ◽  
◽  
...  
Keyword(s):  
Anisotropic Diffusion ◽  
Moisture Absorption ◽  
Practical Importance ◽  
Controlled Environment ◽  
Insulating Materials ◽  
Insulating Material ◽  
One Dimensional ◽  
Dimensional Diffusion ◽  
Traction Electric Motor ◽  
The Ideal

Objective: To develop a method for assessing the degree of moisture absorption by the traction electric motor (TEM) insulation. Methods: Based on the analysis of one-dimensional diffusion of liquid into the insulating material of the TEM windings, it has been shown that cracks increase its saturation with liquid. The proposed analytical solution for anisotropic diffusion of liquid into a cracked insulating material has been investigated. Results: An analytical model has been developed that describes the ideal moisture absorption according to the Fick's law, and it has been shown that it is suitable for calculating the diffusion of moisture into the insulating materials of the TEM windings. Practical importance: Further research should be aimed at obtaining material properties in a moisture-controlled environment

scholarly journals Hopping and Flipping of RNA Polymerase on DNA during Recycling for Reinitiation after Intrinsic Termination in Bacterial Transcription

2021 ◽  
Vol 22 (5) ◽  
pp. 2398
Author(s):  
Wooyoung Kang ◽  
Seungha Hwang ◽  
Jin Young Kang ◽  
Changwon Kang ◽  
Sungchul Hohng
Keyword(s):  
Single Molecule ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Facilitated Diffusion ◽  
One Dimensional ◽  
Bacterial Transcription ◽  
Fluorescence Measurements ◽  
Dimensional Diffusion ◽  
Single Molecule Studies ◽  
Hopping Diffusion

Two different molecular mechanisms, sliding and hopping, are employed by DNA-binding proteins for their one-dimensional facilitated diffusion on nonspecific DNA regions until reaching their specific target sequences. While it has been controversial whether RNA polymerases (RNAPs) use one-dimensional diffusion in targeting their promoters for transcription initiation, two recent single-molecule studies discovered that post-terminational RNAPs use one-dimensional diffusion for their reinitiation on the same DNA molecules. Escherichia coli RNAP, after synthesizing and releasing product RNA at intrinsic termination, mostly remains bound on DNA and diffuses in both forward and backward directions for recycling, which facilitates reinitiation on nearby promoters. However, it has remained unsolved which mechanism of one-dimensional diffusion is employed by recycling RNAP between termination and reinitiation. Single-molecule fluorescence measurements in this study reveal that post-terminational RNAPs undergo hopping diffusion during recycling on DNA, as their one-dimensional diffusion coefficients increase with rising salt concentrations. We additionally find that reinitiation can occur on promoters positioned in sense and antisense orientations with comparable efficiencies, so reinitiation efficiency depends primarily on distance rather than direction of recycling diffusion. This additional finding confirms that orientation change or flipping of RNAP with respect to DNA efficiently occurs as expected from hopping diffusion.

scholarly journals A noninvasive fluorescence imaging-based platform measures 3D anisotropic extracellular diffusion

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Peng Chen ◽  
Xun Chen ◽  
R. Glenn Hepfer ◽  
Brooke J. Damon ◽  
Changcheng Shi ◽  
...  
Keyword(s):  
Anisotropic Diffusion ◽  
Biological Systems ◽  
Three Dimensional ◽  
Molecular Transport ◽  
Light Sheet ◽  
Fundamental Limitations ◽  
Disease Mechanisms ◽  
Dimensional Diffusion ◽  
Compositional Changes ◽  
Diffusion Tensors

AbstractDiffusion is a major molecular transport mechanism in biological systems. Quantifying direction-dependent (i.e., anisotropic) diffusion is vitally important to depicting how the three-dimensional (3D) tissue structure and composition affect the biochemical environment, and thus define tissue functions. However, a tool for noninvasively measuring the 3D anisotropic extracellular diffusion of biorelevant molecules is not yet available. Here, we present light-sheet imaging-based Fourier transform fluorescence recovery after photobleaching (LiFT-FRAP), which noninvasively determines 3D diffusion tensors of various biomolecules with diffusivities up to 51 µm2 s−1, reaching the physiological diffusivity range in most biological systems. Using cornea as an example, LiFT-FRAP reveals fundamental limitations of current invasive two-dimensional diffusion measurements, which have drawn controversial conclusions on extracellular diffusion in healthy and clinically treated tissues. Moreover, LiFT-FRAP demonstrates that tissue structural or compositional changes caused by diseases or scaffold fabrication yield direction-dependent diffusion changes. These results demonstrate LiFT-FRAP as a powerful platform technology for studying disease mechanisms, advancing clinical outcomes, and improving tissue engineering.

The combined effect of lattice’s uniaxial strains and electron–phonon interaction’s screening on TBEC of the intersite bipolarons

2016 ◽  
Vol 30 (26) ◽  
pp. 1650186
Author(s):  
B. Yavidov ◽  
SH. Djumanov ◽  
T. Saparbaev ◽  
O. Ganiyev ◽  
S. Zholdassova ◽  
...  
Keyword(s):  
Ideal Gas ◽  
Einstein Condensation ◽  
Chain Model ◽  
One Dimensional ◽  
Electron Phonon Interaction ◽  
Model Lattice ◽  
Experimental Values ◽  
Bose Einstein ◽  
Derivatives Of ◽  
The Ideal

Having accepted a more generalized form for density-displacement type electron–phonon interaction (EPI) force we studied the simultaneous effect of uniaxial strains and EPI’s screening on the temperature of Bose–Einstein condensation [Formula: see text] of the ideal gas of intersite bipolarons. [Formula: see text] of the ideal gas of intersite bipolarons is calculated as a function of both strain and screening radius for a one-dimensional chain model of cuprates within the framework of Extended Holstein–Hubbard model. It is shown that the chain model lattice comprises the essential features of cuprates regarding of strain and screening effects on transition temperature [Formula: see text] of superconductivity. The obtained values of strain derivatives of [Formula: see text] [Formula: see text] are in qualitative agreement with the experimental values of [Formula: see text] [Formula: see text] of La[Formula: see text]Sr[Formula: see text]CuO4 under moderate screening regimes.

Effect of heterogeneity on the lag time in one‐dimensional diffusion

1988 ◽  
Vol 89 (4) ◽  
pp. 2278-2280 ◽  
Author(s):  
Jenn‐Shing Chen ◽  
Jeffrey L. Fox
Keyword(s):  
Lag Time ◽  
One Dimensional ◽  
Dimensional Diffusion
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