Association between psychological risk factors and ischaemic heart disease in the open population of a large industrial centre of Eastern Siberia
Aim of study. To study gender-based association of high anxiety and depression with ischaemic heart disease exemplified by open population of the city of Krasnoyarsk. Material and methods. A representative sample formed from unoccupied population permanently residing in the city of Krasnoyarsk aged 25-64. Psychometric testing was performed via the Hospital Anxiety and Depression Scale (HADS), the prevalence of ischaemic heart disease was determined based on conventional epidemiological criteria. Results. High values of age-adjusted prevalence of anxiety and depression in the studied sample amounted to 40.1% and 35.0% respectively with no association with the gender. Ischaemic heart disease (IHD) was registered in 10.6% of the patients (15.8% male and 8.6% female subjects, p=0.092). Statistically significant association between IHD and high anxiety (OR=2.39; 95% CI 1.19-4.8; p=0.013) and depression (OR=2.1; 95% CI 1.1-4.1; p=0.031). Gender-discrete analysis has shown analogical associations of IHD with anxiety (OR=4.41; 95% CI 1.57-12.38; р=0.004) and depression (OR=2.91; 95% CI 1.20-7.10; р=0.027) in the female group. Analysis has shown absence of interrelation between the studied risk factors and IHD in the male group of patients. Conclusion. The factor of gender defines association between high anxiety and depression scores according to the HADS in open population of the city of Krasnoyarsk.