The importance of Chakras and Energy Imbalances Correction in the Prevention and Treatment of Gestational Diabetes

IntroductionSelective reporting bias, inconsistency in the chosen outcomes between trials and irrelevance of the chosen outcomes for women, limit the efficiency and value of research for prevention and treatment of gestational diabetes mellitus (GDM). One way to address these challenges is to develop core outcome sets (COSs).Methods and analysisThe aim of this manuscript is to present a protocol for a study to develop COSs for GDM prevention and treatment. This is a three-phase project consisting of (1) a systematic review of the literature to create two lists of outcomes that have been reported in trials and systematic reviews of trials of interventions for the prevention and treatment of GDM, (2) a three-round, web-based e-Delphi survey with key stakeholders to prioritise these outcomes and (3) a consensus meeting to resolve any remaining disagreements and to agree on two COSs.Ethics and disseminationEthical approval to conduct this study was obtained from the ethics committee at Galway University Hospitals on 13 December 2018 (Reference: C.A.2078). We will disseminate our research findings through peer-reviewed, open access publications and present at international conferences to reach a wide range of knowledge users.

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Gestational Diabetes Mellitus pharmacological prevention and treatment

Current Pharmaceutical Design ◽

10.2174/1381612827666210125155428 ◽

2021 ◽

Vol 27 ◽

Author(s):

Chatzakis Christos ◽

Cavoretto Paolo ◽

Sotiriadis Alexandros

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Therapeutic Option ◽

Safety Data ◽

Long Term Effects ◽

Pharmacological Prevention ◽

Oral Agents ◽

Prevention And Treatment

: Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy and is defined as glucose intolerance that first emerges or is first recognized during pregnancy. Several factors increase the risk of a pregnant woman to develop gestational diabetes mellitus and several interventions have been tested for the prevention of GDM development. The most common pharmacological interventions that have been assessed are metformin administration , probiotics administration and vitamin D administration. However, no intervention appears to be universally superior to placebo / no intervention for the prevention of GDM. Administration of insulin is the preferred medication for treating hyperglycemia in gestational diabetes mellitus. Metformin and glyburide are not regarded as first-line agents, as both cross the placenta to the fetus. Even though there are sufficient data indicating that administration of metformin is safe and effective in women with GDM there are very limited data concerning the long-term effects of metformin on offspring. Furthermore, glyburide should be used with caution, as increases the risk of neonatal hypoglycemia and some studies showed that increases also the risk of macrosomia. Overall, oral agents may be a therapeutic option in women with GDM after a discussion of the known risks and the need for more long-term safety data in offspring . The present review aims to highlight that current scientific status regarding the prevention and treatment of GDM.

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The influence of practising physical activity on the prevention and treatment of Gestational Diabetes: a systematic review

Current Diabetes Reviews ◽

10.2174/1573399817666210820110941 ◽

2021 ◽

Vol 17 ◽

Author(s):

Carla Rodríguez-Martínez ◽

Raquel Leirós-Rodríguez

Keyword(s):

Physical Activity ◽

Gestational Diabetes ◽

Eating Habits ◽

Lumbar Pain ◽

Moderate Intensity ◽

Toxic Substances ◽

Therapeutic Exercise ◽

Physical Activity Interventions ◽

Strength Exercises ◽

Prevention And Treatment

Background: During pregnancy, maintaining an inadequate lifestyle (bad eating habits, stress, consumption of toxic substances...) generate complications such as pre-eclampsia, overweight, lumbar pain and Gestational Diabetes. Objective: This review was carried out with the objective of to determine the influence of practising physical activity on the prevention and treatment of Gestational Diabetes; and to evaluate the efficacy of interventions based on therapeutic exercise in the management of such disease. Results: 25 articles were found, 9 were observational studies that analysed physical activity habits through questionnaires, and other 16 applied an intervention. With respect to the frequency of the sessions, most of these studies applied their interventions three times per week, with all of them obtaining positive results. Regarding intensity, all the studies that referred to it concluded that it must be at least moderate, highlighting that, at all times, the limitations of pregnant women must be taken into account. Conclusion: Physical activity interventions must be performed for a minimum of three times per week, at least at moderate intensity, and must be based on aerobic, resistance and strength exercises. Both for the prevention and treatment of this disease, the physical activity must be performed for a minimum of three times per week, at least at moderate intensity, and must be based on aerobic, resistance and strength exercises.

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RATIONALE FOR PREVENTION AND TREATMENT OF GLUCOSE-MEDIATED MACROSOMIA: A PROTOCOL FOR GESTATIONAL DIABETES

Endocrine Practice ◽

10.4158/ep.2.2.118 ◽

1996 ◽

Vol 2 (2) ◽

pp. 118-129 ◽

Cited By ~ 13

Author(s):

Lois Jovanovic-Peterson, MD ◽

Charles M. Peterson, MD

Keyword(s):

Gestational Diabetes ◽

Prevention And Treatment

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The Role of Lifestyle Intervention in the Prevention and Treatment of Gestational Diabetes

Seminars in Reproductive Medicine ◽

10.1055/s-0040-1722208 ◽

2021 ◽

Author(s):

Trine Moholdt ◽

Melanie Hayman ◽

Soulmaz Shorakae ◽

Wendy J. Brown ◽

Cheryce L. Harrison

Keyword(s):

Gestational Diabetes ◽

Lifestyle Modification ◽

Clinical Care ◽

Adverse Outcomes ◽

Large For Gestational Age ◽

Lifestyle Interventions ◽

Maternal Weight ◽

Exercise Interventions ◽

Positive Effects ◽

Prevention And Treatment

AbstractObesity during pregnancy is associated with the development of adverse outcomes, including gestational diabetes mellitus (GDM). GDM is highly associated with obesity and independently increases the risk of both complications during pregnancy and future impaired glycemic control and risk factors for cardiovascular disease for both the mother and child. Despite extensive research evaluating the effectiveness of lifestyle interventions incorporating diet and/or exercise, there remains a lack of definitive consensus on their overall efficacy alone or in combination for both the prevention and treatment of GDM. Combination of diet and physical activity/exercise interventions for GDM prevention demonstrates limited success, whereas exercise-only interventions report of risk reductions ranging from 3 to 49%. Similarly, combination therapy of diet and exercise is the first-line treatment of GDM, with positive effects on maternal weight gain and the prevalence of infants born large-for-gestational age. Yet, there is inconclusive evidence on the effects of diet or exercise as standalone therapies for GDM treatment. In clinical care, women with GDM should be treated with a multidisciplinary approach, starting with lifestyle modification and escalating to pharmacotherapy if needed. Several key knowledge gaps remain, including how lifestyle interventions can be optimized during pregnancy, and whether intervention during preconception is effective for preventing the rising prevalence of GDM.

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