scholarly journals Hepatitis C: Crioglobulinemia y vasculitis cutánea con acronecrosis. Reporte de un caso.

2013 ◽  
Vol 9 (4) ◽  
pp. 155 ◽  
Author(s):  
Rosa MOSTORINO ELGUERA ◽  
Eduardo GOTUZZO HERENCIA ◽  
Víctor ULLOA PEREZ

The C Hepatitis, it is a RNA virus of the Flaviviridae family, that introduces within their spectra of infection, manifestations liverworts and extrahepatic, being these last few frequent. Crioglobulinas could be detected in a third of patient with C hepatitis, but in only 1-2% of the cases develop cutaneous manifestations, some of this manifestatios are vaculitis with acronecrosis. The infection for C hepatitis occurs in other countries with diferent prevalence, they have more prevalence than in our countrie, being different to the prevalence for other types of viral hepatitis (B hepatitis). We are introduced the case of a patient attended to in our department with infection for C hepatitis and extrahepatic manifestations(acronecrosis) associate to presence of crioglobulinas.

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026464 ◽  
Author(s):  
Rob Bielen ◽  
Özgür M Koc ◽  
Dana Busschots ◽  
Geert Robaeys ◽  
Bert Aertgeerts ◽  
...  

ObjectivesChronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) have a major impact on mortality worldwide. Although effective treatments are available for both HBV and HCV infection, <50% of the patients are even diagnosed in Belgium. This study assessed the real-life testing—and diagnosis rate by general practitioners (GPs) in Flanders, Belgium.SettingWe assessed the testing rate for HBV and HCV in 48 primary care practices with electronic medical records linked into one central registry in Flanders, Belgium.ParticipantsThe registry contains data of 440 140 patients over 20 years, which corresponds to 2.2% of the total Flemish population yearly. The primary care practices are distributed across Flanders and the patient population is representative for the distribution of age, gender and socioeconomic status at the community level.ResultsOf 440 140 patients included in the registry, 7892 (1.8%) patients were screened for hepatitis B surface antigen (HBsAg) and 7206 (1.6%) for hepatitis C antibody (HCV Ab) of whom 369 (4.7%) and 163 (2.3%) tested positive, respectively. Of 14 059 patients with chronic liver enzyme elevation, 1112 (7.9%) and 1395 (9.9%) were tested for HBsAg and HCV Ab, respectively. There was no improvement in testing rates over time.ConclusionsThis study demonstrates that real-life testing uptake for viral hepatitis B and C is suboptimal in the general practices in Flanders, even in patients with chronically elevated liver enzymes. As GPs play a crucial role in prevention, diagnosis and linkage to care, efforts and strategies to increase the testing uptake for HBV and HCV are urgently needed.


2011 ◽  
Vol 41 (1) ◽  
pp. 23-25 ◽  
Author(s):  
Haris Riaz ◽  
Talha Riaz ◽  
Faizan Ullah ◽  
Sina Aziz ◽  
Muhammad Ubaid Khan ◽  
...  

Author(s):  
EV Khorkova ◽  
LV Lyalina ◽  
OM Mikailova ◽  
AYu Kovelenov ◽  
YuV Ostankova ◽  
...  

Introduction. To achieve the goal of eliminating viral hepatitis by 2030, it is necessary to assess the real situation, improve epidemiological surveillance and prevention of these infections. Objectives: To evaluate the results of epidemiological surveillance of chronic viral hepatitis B, C, D and hepatocellular carcinoma in order to optimize the surveillance system at the regional level. Materials and methods: We analyzed the incidence of viral hepatitis B, C and liver cancer in the regions of the Northwestern and Central Federal Districts of the Russian Federation over the past 10 years. We also studied the prevalence of hepatitis B, C, D, and hepatitis C virus genotypes (6,020 cases), and examined 465 case histories of patients with hepatocellular carcinoma in the Leningrad Region using techniques of epidemiological analysis, ELISA, PCR, and statistical methods. Results: We established a tendency towards a decrease in the incidence of chronic hepatitis B and C in all study areas. In 2020, high rates of hepatitis B (26.2 and 9.1) and hepatitis C (49.2 and 39.2) were registered in St. Petersburg and Moscow per 100,000 population, respectively. The prevalence of hepatitis D in the Leningrad Region was 6.3 per 100,000 population. Hepatitis C virus genotypes 1 and 3 prevailed (48.9 % and 43.9 %, respectively). A high incidence of liver cancer was established in St. Petersburg, the Pskov and Novgorod Regions. Conclusions: Our findings prove the efficiency of the surveillance system and prevention of chronic hepatitis B and C. The main objectives are to further reduce the incidence rate, screen all patients with chronic hepatitis B for hepatitis D, and use the results of molecular genetic studies and cancer registries for epidemiological surveillance purposes.


2021 ◽  
Vol 104 (3) ◽  
pp. 396-401

Background: Chronic viral hepatitis B (CHB) and chronic viral hepatitis C (CHC) are important causes of chronic liver disease and cancer development in patients with progressive fibrosis, which are often associated with hepatic steatosis. Objective: To evaluate the prevalence of hepatic steatosis in Thai CHB and CHC patients and its correlation with fibrosis stage. Materials and Methods: The authors examined the liver biopsy findings of CHB and CHC patients diagnosed at Srinagarind Hospital between 2016 and 2018. Routine Hematoxylin and Eosin staining with PAS, and Masson trichrome staining were used to evaluate fibrosis and steatosis histology according to the METAVIR and SAF scoring systems. The association were evaluated by chi-square, Fisher’s exact, and Spearman’s correlation tests with statistical significance defined as p-value less than 0.05. Results: One hundred thirty-eight cases were examined. The mean age of the patients was 45 years. Chronic hepatitis C was detected in 96 patients (69.6%), and CHB was detected in 42 patients (30.4%). Liver biopsies showed steatosis in 73 patients (52.9%; grade 1: 67.1%, grade 2: 19.2%, and grade 3: 13.7%). Steatosis was associated with viral hepatitis profile (OR 2.534, 95% CI 1.087 to 5.904, p=0.031); however, the METAVIR fibrosis stage associated with the age of the patient (OR 1.059, 95% CI 1.012 to 1.109, p=0.014) and METAVIR activity (OR 4.924, 95% CI 2.443 to 9.967, p<0.0001). Conclusion: Hepatic steatosis is commonly present in Thai CHC and CHB patients, and especially in the former. Steatosis was associated with viral hepatitis profile. Hepatic fibrosis is associated only with the age of the patient and METAVIR activity. Keywords: Chronic hepatitis B, Chronic hepatitis C, Steatosis, Fibrosis, METAVIR, SAF score, Liver biopsy


2021 ◽  
Vol 9 (4) ◽  
pp. 141
Author(s):  
Leto Olivier Gogbe ◽  
Thomas D’Aquin Toni ◽  
Jean-Jacques Renaud Dechi ◽  
Jean-Louis Philippe N’Din ◽  
Emmanuel Brou ◽  
...  

Author(s):  
Khaled Hassan

Introduction: The establishment of occupational health in all health structures, the improvement of working conditions and the generalization of antiviral B vaccination have contributed to the virtual disappearance of occupational viral hepatitis B and the very significant reduction in the incidence of viral hepatitis C. Aim: to assess knowledge, attitudes and practices on viral hepatitis B and C in health-care settings. Method: cross sectional study using questionnaire. Results: The latter was significantly higher for physicians (72.4%) than for support staff (66.8%) and nurses (60.5%)Viral hepatitis was feared by 82% of caregivers. Only 47.4% of the staff claimed to be correctly vaccinated against hepatitis B. Conclusion: The prevention of occupational viral hepatitis B and C is an objective set by the recommendations issued by the WHO and the CDC. Keyword: Hepatitis B, Hepatitis C


2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Edgardo Jose Escorcia Charris ◽  
Wilson Rafael Marrugo Balceiro

La cirrosis hepática es una de las enfermedades con mayor prevalencia y mortalidad en la población mundial; cuyas etiologías más importantes son de tipo alcohólica, virus de la hepatitis B y C, y esteatosis hepática no alcohólica; la caracterización epidemiológica y clínica, es fundamental para conocer  la casuística actual del problema. Se presenta un estudio descriptivo trasversal retrospectivo, con el objetivo de caracterizar epidemiológicamente y clínicamente a los pacientes con diagnóstico de cirrosis hepática en un centro regional del Caribe Colombiano, que reciben atención en la Unidad de Gastroenterología y hepatología de la Clínica General  del Norte, durante el periodo enero de 2012 a marzo de 2017. Se concluye que la etiología por virus de hepatitis C es la de mayor prevalencia en el medio local, le siguen en frecuencia el hígado graso no alcohólico, la hepatitis autoinmune, la cirrosis biliar primaria, el alcohol, viral hepatitis B y otras etiologías.


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