scholarly journals Assessing testing rates for viral hepatitis B and C by general practitioners in Flanders, Belgium: a registry-based study

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026464 ◽  
Author(s):  
Rob Bielen ◽  
Özgür M Koc ◽  
Dana Busschots ◽  
Geert Robaeys ◽  
Bert Aertgeerts ◽  
...  
Keyword(s):  
Primary Care ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Real Life ◽  
Life Testing ◽  
Viral Hepatitis B ◽  
Testing Uptake ◽  
Care Practices ◽  
Primary Care Practices

ObjectivesChronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) have a major impact on mortality worldwide. Although effective treatments are available for both HBV and HCV infection, <50% of the patients are even diagnosed in Belgium. This study assessed the real-life testing—and diagnosis rate by general practitioners (GPs) in Flanders, Belgium.SettingWe assessed the testing rate for HBV and HCV in 48 primary care practices with electronic medical records linked into one central registry in Flanders, Belgium.ParticipantsThe registry contains data of 440 140 patients over 20 years, which corresponds to 2.2% of the total Flemish population yearly. The primary care practices are distributed across Flanders and the patient population is representative for the distribution of age, gender and socioeconomic status at the community level.ResultsOf 440 140 patients included in the registry, 7892 (1.8%) patients were screened for hepatitis B surface antigen (HBsAg) and 7206 (1.6%) for hepatitis C antibody (HCV Ab) of whom 369 (4.7%) and 163 (2.3%) tested positive, respectively. Of 14 059 patients with chronic liver enzyme elevation, 1112 (7.9%) and 1395 (9.9%) were tested for HBsAg and HCV Ab, respectively. There was no improvement in testing rates over time.ConclusionsThis study demonstrates that real-life testing uptake for viral hepatitis B and C is suboptimal in the general practices in Flanders, even in patients with chronically elevated liver enzymes. As GPs play a crucial role in prevention, diagnosis and linkage to care, efforts and strategies to increase the testing uptake for HBV and HCV are urgently needed.

scholarly journals Hepatitis C: Crioglobulinemia y vasculitis cutánea con acronecrosis. Reporte de un caso.

2013 ◽  
Vol 9 (4) ◽  
pp. 155 ◽  
Author(s):  
Rosa MOSTORINO ELGUERA ◽  
Eduardo GOTUZZO HERENCIA ◽  
Víctor ULLOA PEREZ
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Rna Virus ◽  
Extrahepatic Manifestations ◽  
Cutaneous Manifestations ◽  
Viral Hepatitis B

The C Hepatitis, it is a RNA virus of the Flaviviridae family, that introduces within their spectra of infection, manifestations liverworts and extrahepatic, being these last few frequent. Crioglobulinas could be detected in a third of patient with C hepatitis, but in only 1-2% of the cases develop cutaneous manifestations, some of this manifestatios are vaculitis with acronecrosis. The infection for C hepatitis occurs in other countries with diferent prevalence, they have more prevalence than in our countrie, being different to the prevalence for other types of viral hepatitis (B hepatitis). We are introduced the case of a patient attended to in our department with infection for C hepatitis and extrahepatic manifestations(acronecrosis) associate to presence of crioglobulinas.

Assessment of the seroprevalence of viral hepatitis B, viral hepatitis C and HIV in multitransfused thalassaemia major patients in Karachi, Pakistan

2011 ◽  
Vol 41 (1) ◽  
pp. 23-25 ◽  
Author(s):  
Haris Riaz ◽  
Talha Riaz ◽  
Faizan Ullah ◽  
Sina Aziz ◽  
Muhammad Ubaid Khan ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Thalassaemia Major ◽  
Viral Hepatitis C ◽  
Viral Hepatitis B

Current Issues of Epidemiological Surveillance of Chronic Viral Hepatitis B, C, D and Hepatocellular Carcinoma at the Regional Level

2021 ◽  
pp. 76-84
Author(s):  
EV Khorkova ◽  
LV Lyalina ◽  
OM Mikailova ◽  
AYu Kovelenov ◽  
YuV Ostankova ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Chronic Hepatitis B ◽  
Epidemiological Surveillance ◽  
Leningrad Region ◽  
Hepatitis D ◽  
Viral Hepatitis B

Introduction. To achieve the goal of eliminating viral hepatitis by 2030, it is necessary to assess the real situation, improve epidemiological surveillance and prevention of these infections. Objectives: To evaluate the results of epidemiological surveillance of chronic viral hepatitis B, C, D and hepatocellular carcinoma in order to optimize the surveillance system at the regional level. Materials and methods: We analyzed the incidence of viral hepatitis B, C and liver cancer in the regions of the Northwestern and Central Federal Districts of the Russian Federation over the past 10 years. We also studied the prevalence of hepatitis B, C, D, and hepatitis C virus genotypes (6,020 cases), and examined 465 case histories of patients with hepatocellular carcinoma in the Leningrad Region using techniques of epidemiological analysis, ELISA, PCR, and statistical methods. Results: We established a tendency towards a decrease in the incidence of chronic hepatitis B and C in all study areas. In 2020, high rates of hepatitis B (26.2 and 9.1) and hepatitis C (49.2 and 39.2) were registered in St. Petersburg and Moscow per 100,000 population, respectively. The prevalence of hepatitis D in the Leningrad Region was 6.3 per 100,000 population. Hepatitis C virus genotypes 1 and 3 prevailed (48.9 % and 43.9 %, respectively). A high incidence of liver cancer was established in St. Petersburg, the Pskov and Novgorod Regions. Conclusions: Our findings prove the efficiency of the surveillance system and prevention of chronic hepatitis B and C. The main objectives are to further reduce the incidence rate, screen all patients with chronic hepatitis B for hepatitis D, and use the results of molecular genetic studies and cancer registries for epidemiological surveillance purposes.

Association between Hepatic Steatosis and Fibrosis in Chronic Viral Hepatitis B and C Patients

2021 ◽  
Vol 104 (3) ◽  
pp. 396-401
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Liver Biopsy ◽  
Viral Hepatitis ◽  
Hepatic Steatosis ◽  
Chronic Hepatitis C ◽  
Chronic Viral Hepatitis ◽  
Fibrosis Stage ◽  
Viral Hepatitis B

Background: Chronic viral hepatitis B (CHB) and chronic viral hepatitis C (CHC) are important causes of chronic liver disease and cancer development in patients with progressive fibrosis, which are often associated with hepatic steatosis. Objective: To evaluate the prevalence of hepatic steatosis in Thai CHB and CHC patients and its correlation with fibrosis stage. Materials and Methods: The authors examined the liver biopsy findings of CHB and CHC patients diagnosed at Srinagarind Hospital between 2016 and 2018. Routine Hematoxylin and Eosin staining with PAS, and Masson trichrome staining were used to evaluate fibrosis and steatosis histology according to the METAVIR and SAF scoring systems. The association were evaluated by chi-square, Fisher’s exact, and Spearman’s correlation tests with statistical significance defined as p-value less than 0.05. Results: One hundred thirty-eight cases were examined. The mean age of the patients was 45 years. Chronic hepatitis C was detected in 96 patients (69.6%), and CHB was detected in 42 patients (30.4%). Liver biopsies showed steatosis in 73 patients (52.9%; grade 1: 67.1%, grade 2: 19.2%, and grade 3: 13.7%). Steatosis was associated with viral hepatitis profile (OR 2.534, 95% CI 1.087 to 5.904, p=0.031); however, the METAVIR fibrosis stage associated with the age of the patient (OR 1.059, 95% CI 1.012 to 1.109, p=0.014) and METAVIR activity (OR 4.924, 95% CI 2.443 to 9.967, p<0.0001). Conclusion: Hepatic steatosis is commonly present in Thai CHC and CHB patients, and especially in the former. Steatosis was associated with viral hepatitis profile. Hepatic fibrosis is associated only with the age of the patient and METAVIR activity. Keywords: Chronic hepatitis B, Chronic hepatitis C, Steatosis, Fibrosis, METAVIR, SAF score, Liver biopsy

Hepatitis C Virus Screening and Care: Complexity of Implementation in Primary Care Practices Serving Disadvantaged Populations

2019 ◽  
Vol 171 (12) ◽  
pp. 865 ◽  
Author(s):  
Barbara J. Turner ◽  
Andrea Rochat ◽  
Sarah Lill ◽  
Raudel Bobadilla ◽  
Ludivina Hernandez ◽  
...  
Keyword(s):  
Primary Care ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Disadvantaged Populations ◽  
Care Practices ◽  
Primary Care Practices ◽  
Virus Screening

scholarly journals Room for Improvement: Rates of Birth Cohort Hepatitis C Screening in Primary Care Practices—A WWAMI Region Practice and Research Network Study

2019 ◽  
Vol 10 ◽  
pp. 215013271988429 ◽  
Author(s):  
Allison M. Cole ◽  
Gina A. Keppel ◽  
Laura-Mae Baldwin ◽  
Ryan Gilles ◽  
John Holmes ◽  
...  
Keyword(s):  
United States ◽  
Primary Care ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Birth Cohort ◽  
The United States ◽  
Research Network ◽  
Health Record ◽  
Care Practices ◽  
Primary Care Practices

Introduction: An estimated 2.4 million people in the United States live with hepatitis C. Though there are effective treatments for chronic hepatitis C, many infected individuals remain untreated because 40% to 50% of individuals with chronic hepatitis C are unaware of their hepatitis C status. In 2013, the United States Preventive Services Task Force (USPSTF) recommended that adults born between 1945 and 1965 should be offered one-time hepatitis C screening. The purpose of this study is to describe rates of birth cohort hepatitis C screening across primary care practices in the WWAMI region Practice and Research Network (WPRN). Methods: Cross-sectional observational study of adult patients born between 1945 and 1965 who also had a primary care visit at 1 of 9 participating health systems (22 primary care clinics) between July 31, 2013 and September 30, 2015. Data extracted from the electronic health record systems at each clinic were used to calculate the proportion of birth cohort eligible patients with evidence of hepatitis C screening as well as proportions of screened patients with positive hepatitis C screening test results. Results: Of the 32 139 eligible patients, only 10.9% had evidence of hepatitis C screening in the electronic health record data (range 1.2%-49.1% across organizations). Among the 4 WPRN sites that were able to report data by race and ethnicity, the rate of hepatitis C screening was higher among African Americans (39.9%) and American Indians/Alaska Natives (23.2%) compared with Caucasians (10.7%; P < .001). Discussion: Rates of birth cohort hepatitis C screening are low in primary care practices. Future research to develop and test interventions to increase rates of birth cohort hepatitis C screening in primary care settings are needed.

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