scholarly journals Newly recognized extratumoral features of colorectal cancer challenge the current tumor-node-metastasis staging system

2018 ◽  
Author(s):  
Elias Athanasakis
Keyword(s):  
Colorectal Cancer ◽  
Staging System ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
Tumor Node Metastasis Staging

Assessment of the Relation between Serum Carcinoembryonic Antigen and Tumor Node Metastasis Staging of Colorectal Cancer

2021 ◽  
Vol 85 (2) ◽  
pp. 3898-3892
Author(s):  
Nouralddeen Ahmed Kareemeed ◽  
Alaa Mohamed Ibrahim Khalil ◽  
Wael Elsayed Lotfy Mokhtar ◽  
Hassan Rabea Galal Ashour
Keyword(s):  
Colorectal Cancer ◽  
Carcinoembryonic Antigen ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
Serum Carcinoembryonic Antigen ◽  
Tumor Node Metastasis Staging

scholarly journals Comparison of Characteristics and Survival Rates of Resectable Pancreatic Ductal Adenocarcinoma according to Tumor Location

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1706
Author(s):  
Min Kyu Sung ◽  
Yejong Park ◽  
Bong Jun Kwak ◽  
Eunsung Jun ◽  
Woohyung Lee ◽  
...  
Keyword(s):  
Survival Rates ◽  
Disease Free Survival ◽  
Staging System ◽  
Tumor Location ◽  
Ductal Adenocarcinoma ◽  
Tumor Node Metastasis ◽  
Free Survival ◽  
Node Metastasis ◽  
Tumor Node Metastasis Staging ◽  
Disease Free

The impact of tumor location on patient survival in pancreatic ductal adenocarcinoma (PDAC) remains controversial. This study investigated the association between primary tumor location and survival rates for resectable PDAC. Additionally, we assessed if this association remains consistent across categories of the Tumor-Node-Metastasis staging system. We analyzed 2471 patients who underwent surgical resection between 2000 and 2018 at a single center. Subgroup analysis was performed according to the Tumor-Node-Metastasis staging system. Among the group, 67.9% (1677 patients) had pancreatic head cancer (PHC) and 32.1% (794 patients) had pancreatic body/tail cancer (PBTC). Patients with PHC had worse overall survival and worse disease-free survival than those with PBTC. Patients with PHC had worse survival in stage IB and stage IIB than those with PBTC. No significant difference was observed for stages IA, IIA, and III. Multivariate analysis showed that elevated CA 19-9, mGPS, a longer hospital stay, complication, accompanying vein resection, larger tumor size, worse differentiation, higher TNM stage (stage IIB, III, IV), presence of LVI, and positive resection margin were risk factors for poor survival after resection. In resectable PDAC, patients with PHC had worse overall and disease-free survival than those with PBTC. However, tumor location was not an independent prognostic factor for PDAC.

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