scholarly journals MULTISLICE COMPUTED TOMOGRAPHY TO MEASURE VISCERAL FAT AREA IN PATIENT WITH ASTHMA AND OBESITY

2018 ◽  
Vol 99 (5) ◽  
pp. 264-268
Author(s):  
N. S. Serova ◽  
N. V. Chichkova ◽  
A. A. Gasparyan ◽  
L. B. Kapanadze ◽  
V. V. Fomin

Asthma and obesity prevalence in population have increased over the last years. In the Global Strategy for Asthma Management and Prevention (GINA, 2017) the “asthma-obesity” phenotype is identified, it has certain clinical features, disease course and response to therapy. One of the hypotheses explaining the relationship between asthma and obesity is the systemic inflammation theory. The visceral adipose tissue (VAT) plays a key role in this hypothesis, it produces various adipokines, imbalance of which results in the state of mild inflammation. With that only the body mass index (BMI) is used to diagnose obesity in asthma patients, but BMI doesn’t take into account the amount of VAT in the body.The clinical case of a patient with asthma in combination with third degree of obesity is presented. Additionally the patient was given a multislice computed tomography to measure the visceral and subcutaneous fat areas, followed by an evaluation of the obtained data and a collation of the parameters with clinical and anthropometric characteristics.

2003 ◽  
Vol 149 (6) ◽  
pp. 543-548 ◽  
Author(s):  
AG Rockall ◽  
SA Sohaib ◽  
D Evans ◽  
G Kaltsas ◽  
AM Isidori ◽  
...  

OBJECTIVE: Hepatic steatosis may occur in association with insulin resistance and obesity, two features commonly seen in Cushing's syndrome (CS). The aim of this report is to assess the prevalence of hepatic steatosis in patients with active CS using computed tomography (CT) and to identify any associations between hepatic steatosis, endocrine and biochemical variables and body fat distribution. PATIENTS AND MEASUREMENTS: We identified 50 patients with active CS in whom appropriate CT was available to allow measurement of liver and spleen attenuation. In 26 patients, abdominal fat measurements were also available. Serum markers of CS and liver function tests were recorded. RESULTS: Ten of 50 patients had a liver-to-spleen CT attenuation ratio (L/S) of less than 1, indicating hepatic steatosis. There was a significant negative correlation between both liver attenuation and L/S ratio with total abdominal fat area, visceral fat area, the percentage of visceral fat and the visceral to subcutaneous fat ratio; the strongest negative correlation was found between visceral fat area and L/S ratio (r=-0.638, P<0.001, n=26). L/S ratio positively correlated with alkaline phosphatase levels (r=+0.423, P=0.044, n=23) but with no other serum marker of CS activity or liver enzyme. CONCLUSIONS: We have demonstrated hepatic steatosis on CT in 20% of patients with active CS. The presence of hepatic steatosis was significantly correlated with total abdominal fat area and visceral fat area.


2021 ◽  
Author(s):  
Yu-San Tee ◽  
Chi-Tung Cheng ◽  
Chi-Hsun Hsieh ◽  
Shih-Ching Kang ◽  
CHIH-YUAN FU ◽  
...  

Abstract Background: The severity of injury from motor vehicle crashes (MVCs) depends on complex biomechanical factors, and the body features of the injured person account for some of these factors. By assuming that vulnerable road users (VRU) have limited protection resulting from vehicle and safety equipment, the current study analyzed the characteristics of fat distribution measured by computed tomography (CT) imaging and investigated the existence of a “Cushion effect” in VRU.Materials and Methods: This retrospective study enrolled 592 VRU involved in MVCs who underwent CT scans. Visceral fat area and subcutaneous fat cross-sectional area were measured and adjusted according to total body area (TBA) and are presented as the visceral fat ratio and the subQ fat ratio (subcutaneous fat ratio). Risk factors for serious abdominal injury [maximum abbreviated injury scale (MAISabd ≥ 3)] resulting from MVCs were determined by univariate and multivariate analysis.Results: MAISabd ≥ 3 was observed in 104 (17.6%) of the patients. The SubQ fat ratio at the L4 vertebral level was significantly lower in the MAISabd ≥ 3 group than in the MAISabd < 3 group (24.9 ± 12.0 vs 28.1 ± 11.9%; p=0.015). A decreased L4 subQ fat ratio was associated with a higher risk for MAISabd ≥ 3 in multivariate analysis (odds ratio 0.063; 95% CI 0.008-0.509; p = 0.009).Conclusion: The current study supported the “Cushion effect” theory, and protection was apparently provided by subcutaneous fat tissue. This concept may further improve vehicle and safety designation in the future.


2017 ◽  
Vol 9 (10) ◽  
pp. 78
Author(s):  
Masato Mizui ◽  
Yuji Mizoguchi ◽  
Yutaka Senda ◽  
Masayuki Yokoi ◽  
Takao Tashiro

In Japan, the measurement of abdominal circumference is commonly used in diagnosis of visceral fat accumulation. It is also recommended that visceral fat at the umbilical level be measured using CT scans. If CT is used to measure the visceral fat area, we do not have to consider the possibility of measurement error due to subcutaneous fat. However, it is unknown whether the visceral fat area measurement by CT reflects the visceral fat volume of the entire abdomen.We examined the correlation between the visceral fat area at the umbilical level and the visceral fat volume of the entire abdomen using CT images taken from the diaphragm to the pubic bone.The results showed that there was a very high correlation between the visceral fat area and the visceral fat volume. The correlation was not affected by gender differences, old age or whether visceral fat was accumulated or not.Therefore, we concluded that it is possible to estimate the visceral fat volume of the entire abdomen by measuring the visceral fat area at the umbilical level.


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