scholarly journals Loneliness and Neurocognitive Aging

Keyword(s):  
AGE ◽  
2006 ◽  
Vol 28 (3) ◽  
pp. 221-233 ◽  
Author(s):  
Michela Gallagher ◽  
Carlo Colantuoni ◽  
Howard Eichenbaum ◽  
Rebecca P. Haberman ◽  
Peter R. Rapp ◽  
...  

Diabetes Care ◽  
2020 ◽  
Vol 43 (5) ◽  
pp. 1111-1117 ◽  
Author(s):  
Hector M. González ◽  
Wassim Tarraf ◽  
Kevin A. González ◽  
Myriam Fornage ◽  
Donglin Zeng ◽  
...  

2019 ◽  
Vol 15 (12) ◽  
pp. 1507-1515 ◽  
Author(s):  
Hector M. González ◽  
Wassim Tarraf ◽  
Neil Schneiderman ◽  
Myriam Fornage ◽  
Priscilla M. Vásquez ◽  
...  

Author(s):  
Hana Burianová

Determining the mechanisms that underlie neurocognitive aging, such as compensation or dedifferentiation, and facilitating the development of effective strategies for cognitive improvement is essential due to the steadily rising aging population. One approach to study the characteristics of healthy aging comprises the assessment of functional connectivity, delineating markers of age-related neurocognitive plasticity. Functional connectivity paradigms characterize complex one-to-many (or many-to-many) structure–function relations, as higher-level cognitive processes are mediated by the interaction among a number of functionally related neural areas rather than localized to discrete brain regions. Task-related or resting-state interregional correlations of brain activity have been used as reliable indices of functional connectivity, delineating age-related alterations in a number of large-scale brain networks, which subserve attention, working memory, episodic retrieval, and task-switching. Together with behavioral and regional activation studies, connectivity studies and modeling approaches have contributed to our understanding of the mechanisms of age-related reorganization of distributed functional networks; specifically, reduced neural specificity (dedifferentiation) and associated impairment in inhibitory control and compensatory neural recruitment.


2020 ◽  
Vol 77 (3) ◽  
pp. 1267-1278
Author(s):  
Ariana M. Stickel ◽  
Wassim Tarraf ◽  
Benson Wu ◽  
Maria J. Marquine ◽  
Priscilla M. Vásquez ◽  
...  

Background: Among older adults, poorer cognitive functioning has been associated with impairments in instrumental activities of daily living (IADLs). However, IADL impairments among older Hispanics/Latinos is poorly understood. Objective: To characterize the relationships between cognition and risk for IADL impairment among diverse Hispanics/Latinos. Methods: Participants included 6,292 community-dwelling adults from the Study of Latinos - Investigation of Neurocognitive Aging, an ancillary study of 45+ year-olds in the Hispanic Community Health Study/Study of Latinos. Cognitive data (learning, memory, executive functioning, processing speed, and a Global cognitive composite) were collected at Visit 1. IADL functioning was self-reported 7 years later, and treated as a categorical (i.e., risk) and continuous (i.e., degree) measures of impairment. Survey two-part models (mixture of logit and generalized linear model with Gaussian distribution) and ordered logistic regression tested the associations of cognitive performance (individual tests and composite z-score) with IADL impairment. Additionally, we investigated the moderating role of age, sex, and Hispanic/Latino background on the association between cognition and IADL impairment. Results: Across all cognitive measures, poorer performance was associated with higher odds of IADL impairment 7 years later. Associations were generally stronger for the oldest group (70+ years) relative to the youngest group (50–59 years). Sex and Hispanic/Latino background did not modify the associations. Across the full sample, lower scores on learning, memory, and the Global cognitive composite were also associated with higher degree of IADL impairment. Conclusion: Across diverse Hispanics/Latinos, cognitive health is an important predictor of everyday functioning 7 years later, especially in older adulthood.


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