scholarly journals Congenital Syphilis: A U.S. Perspective

Author(s):  
Alvaro Galvis ◽  
Antonio Arrieta

Congenital syphilis still represents a worldwide public health problem. If left untreated, can lead to fetal demise and high neonatal morbidity and mortality. Unfortunately, in the last decade there has been a resurgence of cases in the US. This review discusses the ongoing problem of this preventable congenital infection, vertical transmission and clinical manifestations while providing a guidance for the evaluation and management of infants born to mothers with reactive serologic tests for syphilis

Children ◽  
2020 ◽  
Vol 7 (11) ◽  
pp. 203
Author(s):  
Alvaro E. Galvis ◽  
Antonio Arrieta

Congenital syphilis still represents a worldwide public health problem. If left untreated, it can lead to fetal demise and high neonatal morbidity and mortality. Unfortunately, in the last decade, there has been a resurgence of cases in the U.S. This review discusses the ongoing problem of this preventable congenital infection, vertical transmission and clinical manifestations while providing a guidance for the evaluation and management of infants born to mothers with reactive serologic tests for syphilis.


Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 667
Author(s):  
Daniela Eugenia Popescu ◽  
Andreea Cioca ◽  
Cezara Muresan ◽  
Dan Navolan ◽  
Arina Gui ◽  
...  

Coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic causing a serious global public health problem. The risk of vertical transmission of SARS-CoV-2 is still debated, and the consequences of this virus on pregnant women and their fetuses remain unknown. We report a case of pregnancy complicated with hydrops fetalis that developed 7 weeks after recovery from a mild SARS-CoV-2 infection, leading to intrauterine death of the foetus. Evidence of SARS-CoV-2 placentitis was demonstrated by the presence of viral particles in the placenta identified by immunohistochemistry. As we excluded all possible etiological factors for non-immunologic hydrops fetalis, we believe that the fetal consequences of our case are related to vertical transmission of SARS-CoV-2 virus. To the best of our knowledge, this is the second reported case in the literature of COVID-19 infection complicated with hydrops fetalis and intrauterine fetal demise.


2019 ◽  
Vol 18 (4) ◽  
pp. 198-229
Author(s):  
Kaic Trindade Almeida ◽  
Álisson Neves Santos ◽  
Ana Karla Araújo Nascimento Costa ◽  
Myllena Rodrigues dos Santos ◽  
Ana Maria Fernandes Menezes ◽  
...  

Objective: To analyze the epidemiological profile of Congenital Syphilis in 18 municipalities in the state of Bahia between 2007 and 2017.Method: A descriptive, cross-sectional and quantitative study of the confirmed cases of Congenital Syphilis in the micro-region registered in the Aggravation and Notification Information System.Results: In the study period, 39 cases were confirmed, with 30.8% of the mothers being between 20 and 24 years of age, 59% were brown, 46.2% had incomplete primary education, 33.3% were housewives, 74.4% 94.9% underwent prenatal care, 53.8% were diagnosed at the time of delivery / curettage, 41% received inadequate treatment and 38.5% of the partners were not treated. With regard to newborns, 69.2% were diagnosed with 0 day of life, 74.4% with recent Congenital Syphilis and 46.2% asymptomatic.Conclusion: The data reveal a serious public health problem in the micro-region analyzed, also pointing out failures in the notification system, observed in the high ignored index in the studied variables. Objetivo: Analizar el perfil epidemiológico de Sífilis Congénita en 18 municipios en el interior del estado de Bahía entre 2007 y 2017.Método: Estudio descriptivo, transversal y cuantitativo de los casos confirmados de Sífilis Congénita en la microrregión registrados en el Sistema de Información de Agravios y Notificación.Resultados: En el período estudiado se confirmaron 39 casos, donde el 30,8% de las madres tiene entre 20 a 24 años, el 59% son pardas, el 46,2% tienen enseñanza fundamental incompleta, el 33,3% amas de casa, el 74,4% en el momento del parto / curetaje, el 41% recibió tratamiento inadecuado y el 38,5% de los socios no fueron tratados. Con respecto a los recién nacidos, el 69,2% fue diagnosticado con 0 días de vida, 74,4% con Sífilis Congénita reciente y 46,2% asintomáticos.Conclusión: Los datos revelan un serio problema de salud pública en la microrregión analizada apuntando también fallas en el sistema de notificación, observadas en el elevado índice de ignorados en las variables estudiadas. Objetivo: Analisar o perfil epidemiológico de Sífilis Congênita em 18 municípios no interior do estado da Bahia entre 2007 e 2017. Método: Estudo descritivo, transversal e quantitativo dos casos confirmados de Sífilis Congênita na microrregião registrados no Sistema de Informação de Agravos e Notificação. Resultados: No período estudado foram confirmados 39 casos, onde 30,8% das mães tem entre 20 a 24 anos, 59% são pardas, 46,2% possuem ensino fundamental incompleto, 33,3% donas de casa, 74,4% residentes na zona urbana, 94,9% realizou o pré-natal, 53,8% foram diagnosticadas no momento do parto/curetagem, 41% receberam tratamento inadequado e 38,5% dos parceiros não foram tratados. Com relação aos recém-nascidos, 69,2% foram diagnosticados com 0 dia de vida, 74,4% com Sífilis Congênita recente e 46,2% assintomáticos. Conclusão: Os dados revelam um sério problema de saúde pública na microrregião analisada apontando também falhas no sistema de notificação, observadas no elevado índice de ignorados nas variáveis estudadas.


2020 ◽  
Vol 04 (01) ◽  
pp. 40-46
Author(s):  
Chitra Mehta ◽  
Sushila Kataria ◽  
Yatin Mehta

AbstractCoronavirus 2019 (COVID-19) disease is the most recent global public health problem. It is caused by SARS-CoV-2 (severe acute respiratory syndrome related coronavirus 2), which is a RNA virus with a high mutation rate, belonging to the genus Coronavirus. The objective of this communication is to provide an initial understanding regarding pathophysiology, clinical manifestations, management, and prevention of this devastating disease.


2012 ◽  
Vol 63 (4) ◽  
pp. 308-311
Author(s):  
Adriana Raquel Cruz-Concha

Syphilis is a sexually transmitted infection (STI) caused by Treponema Pallidum, and is considered a serious public health problem as it affects more than 12 million people worldwide. It is estimated that over two million pregnant women are infected with syphilis each year worldwide, and a significant number of cases (692,100 to 1,53 million), are untreated (1). When it occurs in pregnant women it is easily transmitted to the fetus, causing complications in up to 81% of cases, including stillbirth, early neonatal death , prematurity, low birth weight or congenital infection (2).In Colombia, gestational and congenital syphilis is notifiable, and the figures reported by the System of Public Health Surveillance (sivigila, for its acronym in Spanish), are among the highest in Latin America and the Caribbean. In 2011 Colombia reported 2.9 cases of congenital syphilis / 1000 live births (3), a value which is worth almost six times higher than the target set by the Pan American Health Organization (PAHO) in its Elimination of Congenital Syphilis Plan (2, 4). The Colombian Pacific coast provides the country with a significant number of cases each year, being the port of Buenaventura, in Valle del Cauca, one of the worst affected areas, reporting on 2010, 141 cases of congenital syphilis, nine of which ended in a fatal outcome (5).


2018 ◽  
Vol 6 (9) ◽  
pp. 64
Author(s):  
James F. Anderson ◽  
Kelley Reinsmith-Jones ◽  
Laronistine Dyson ◽  
Adam H. Langsam

While the opioid crisis in the US has been widely publicized, what has not been given equal attention is the increasing number of pregnant women addicted to various prescribed and illegal opioids which has paralleled the current opioid epidemic. Instead of viewing the matter as a criminal justice issue, many experts believe that the issue is a public health problem because of the sheer number of people who are impacted nationwide, as well as the negative health consequences that affect the mothers and infants. We argue that opioid addicted pregnant women is not a criminal justice issue, but rather, a public health epidemic that requires healthcare approaches rather than punitive criminal justice strategies.


Author(s):  
Dr. Pradeep Kumar Jena ◽  
◽  
Dr. Swasthi Kabi Satapathy ◽  
Dr. Alok Satya Prakash Nayak ◽  
Dr. Sarthak NaIik ◽  
...  

Scrub typhus is a major public health problem in India with a wide spectrum of clinicalmanifestations and a low index of suspicion is low endemic areas which in turn can increasemorbidity and mortality. The clinical manifestations of scrub typhus can range from mild non-specificfebrile illness or constitutional symptoms such as fever, rash, myalgia, headache to various organdysfunction such as AKI, myocarditis, pneumonia, meningitis, encephalitis, GI bleed, hepatitis. Herewe report a case of a 9-year-old girl who presented with scrub septicemia and progressed to developcritical illness myopathy, which is very unusual.


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