scholarly journals The differences in homeostasis model assessment values in type 2 diabetic patients with different lengths of history of diabetes

2019 ◽  
Author(s):  
Chen Wang ◽  
Zaibo Liu ◽  
Peng Zhang ◽  
Xiaolong Ma ◽  
Kui Che ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Model Assessment ◽  
Homeostasis Model Assessment ◽  
Type 2 Diabetic Patients ◽  
History Of ◽  
Type 2 Diabetic

Homeostasis model assessment (HOMA) in type 2 diabetic patients

2000 ◽  
Vol 50 ◽  
pp. 343
Author(s):  
Freddy Contreras ◽  
V Bermúdez ◽  
C Cano ◽  
A Souki ◽  
M Medina ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Model Assessment ◽  
Homeostasis Model Assessment ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Objectivization of vacuum-compression therapy effects on micro- and macrovascular perfusion in type 2 diabetic patients

2020 ◽  
Vol 65 (4) ◽  
pp. 469-476
Author(s):  
Jaroslav Prucha ◽  
Vladimir Socha ◽  
Lenka Hanakova ◽  
Andrej Lalis ◽  
Karel Hana
Keyword(s):  
Lower Limb ◽  
Compression Therapy ◽  
Neurological Complications ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Therapeutic Procedures ◽  
History Of ◽  
Injury Recovery ◽  
Type 2 Diabetic

AbstractThe present study aimed to evaluate the characteristic influence of physical therapeutic procedures of vacuum-compression therapy (VCT) on microvascular perfusion (MiP) and macrovascular perfusion (MaP) of the lower limb in diabetic patients. A sample of nine patients with a medical history of type 2 diabetes was used for the purpose of this study. Most of the subjects’ medical conditions included venous and neurological complications of the lower limb, whereas the rest of the subjects entered the treatment due to injury recovery or their phlebological disease. The PeriFlux System 5000 (Perimed, Sweden) diagnostic device was used to measure MiP. The MaP was evaluated based on the perfusion index (PI) using the Extremiter monitoring device (Embitron, Czech Republic) designed to perform VCT procedures. The study found that MiP and MaP increase as an effect of VCT procedures and at the same time PI clearly reflects the effect of the applied vacuum and compression phases, verifying the method’s vital influence on peripheral perfusion disorders.

scholarly journals Effect of pioglitazone on serum concentrations of osteoprotegerin in patients with type 2 diabetes mellitus

2011 ◽  
Vol 164 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Jong Suk Park ◽  
Min Ho Cho ◽  
Ji Sun Nam ◽  
Jeong Seon Yoo ◽  
Chul Woo Ahn ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Model Assessment ◽  
Type 2 Diabetic Patients ◽  
Reactive Protein ◽  
Regulatory Molecule ◽  
Metformin Group ◽  
Pioglitazone Group ◽  
Design And Methods ◽  
Type 2 Diabetic

ObjectiveOsteoprotegerin (OPG) acts as an important regulatory molecule in atherosclerosis. Recent studies report that thiazolidinediones could affect OPG expression. We investigated the relationship between OPG and inflammatory cytokines and the effects of pioglitazone (a PPARγ (PPARG) agonist) versus metformin on serum OPG levels in type 2 diabetic patients.Design and methodsSixty-seven type 2 diabetic patients were included in this study. They were assigned to pioglitazone (15 mg/day,n=34) or metformin (1000 mg/day,n=33) during 24 weeks. Various anthropometric and metabolic parameters, OPG, interleukin 6 (IL6), C-reactive protein (CRP), adiponectin, and homeostasis model assessment of insulin resistance (HOMA-IR), were measured at baseline and at 6 months of treatment.ResultsSerum OPG levels correlated significantly with fasting plasma glucose (FPG), HbAlc, HOMA-IR, IL6, and CRP, and inversely correlated with adiponectin after adjusting for age (P<0.05). Multiple regression analysis showed that FPG, HbAlc, and adioponectin were independently correlated with OPG level. After 6 months of treatment, the reduction in FPG and HbAlc levels was similar between the two groups. Pioglitazone treatment significantly increased body mass index (P<0.05) and waist circumference (P<0.05) and decreased triglycerides (P<0.05) and HOMA-IR (P<0.01). The adiponectin concentration was increased (P<0.05), and OPG and CRP levels were decreased in the pioglitazone group (P<0.05), but were unchanged in the metformin group. The changes in serum OPG in the pioglitazone group showed significant correlation with changes in FPG, HbAlc, and adiponectin.ConclusionsIn type 2 diabetic patients, pioglitazone decreases OPG levels, and this decrease in OPG levels might be associated with the increase in adiponectin.

scholarly journals Raised Arterial Pressure and Microalbuminuria in Type 2 Diabetic Subjects with Familial Hypertension

2016 ◽  
Vol 4 (1) ◽  
pp. 14-18
Author(s):  
Md Anisur Rahman ◽  
Md Mostarshid Billah ◽  
Palash Mitra ◽  
Md Emtiaz Hossan ◽  
Md Jakir Hossain ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Pressure ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Familial Predisposition ◽  
Significant Difference ◽  
History Of ◽  
Family History Of Hypertension ◽  
Type 2 Diabetic

Background and Aims : Microalbuminuria is claimed to be an early marker of nephropathy in type 2 diabetes.The raised arterial pressure is an important factor in the progression of diabetic nephropathy. There is a significant correlation between blood pressure and the progression of albuminuria in both type 1 and type 2 diabetes. This study in Bangladeshi type 2 diabetic patients was to evaluate whether microalbuminuria and raised arterial pressure are influenced by familial predisposition to hypertension.Methods : Sixty three newly diagnosed Bangladeshi type 2 diabetic patients were investigated. The diabetic subjects were divided into two groups as diabetes with family history of hypertension (n=37) and diabetes without family history of hypertension (n=26). Diabetic subjects were further divided into normotensive (n= 46) and hypertensive (n= 17); diabetic normoalbuminuric (n 44) and diabetic microalbuminuric (n 19) subgroups. Serum glucose was measured by glucose-oxidase; blood urea, serum creatinine and urinary creatinine by enzymatic-colorimetric method and urinary albumin by immunoturbidimetry method.Results : systolic blood pressure (SBP), diastolic blood pressure (DBP) and microalbuminuria were significantly elevated in diabetic subjects with familial predisposition to hypertension when compared to diabetic subjects without familial predisposition to hypertension [SBP (127±16 vs 110±14) mmHg P= 0.001; DBP (81±9 vs 72±11) mmHg P= 0.001; Microalbuminuria 2.23(0.28-9.43) vs 1.52(.29-3.91) mg/mmol p<0.03]. When diabetic normotensive subjects were compared with diabetic hypertensive subjects for microalbuminuria, no significant difference was found among themselves [median (range) 1.67(0.17-8.62) vs 1.70(.28-9.43) mg/mmol p = NS]. Comparison of blood pressure was found no significant difference between diabetic normoalbuminuric and diabetic microalbuminuric subjects [systolic blood pressure (117±17 vs 125±17) mmHg p= NS ; diastolic blood pressure (76±11 vs 82±10) mmHg p= NS ].Conclusion : Microalbuminuria, a marker of early diabetic nephropathy and raised arterial pressure, a progression factor of nephropathy are more influenced by familial predisposition to hypertension in diabetic population irrespective of presence or absence of microalbuminuria and hypertension.Bangladesh Crit Care J March 2016; 4 (1): 14-18

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