High-altitude climate therapy for children with immune thrombocytopenia in the Kyrgyz Republic

2020 ◽  
Vol 15 (1) ◽  
pp. 81-86
Author(s):  
S.M. Mamatov ◽  
◽  
G.Sh. G.Sh.Maymerova ◽  
Ayzhamal Esengeldi kyzy ◽  
A.O. Musakeev ◽  
...  
Keyword(s):  
High Altitude ◽  
Immune Thrombocytopenia ◽  
Kyrgyz Republic

Results of high-altitude climate treatment of immune thrombocytopenia in children in the Kyrgyz Republic (five-year analysis)

2020 ◽  
Author(s):  
А.К. Эсенгелди
Keyword(s):  
High Altitude ◽  
Immune Thrombocytopenia ◽  
Disease Duration ◽  
Objective Response ◽  
Kyrgyz Republic ◽  
Chronic Itp ◽  
Effi Ciency ◽  
The Subject ◽  
Further Development

Введение: Вопрос о дальнейшем совершенствовании базисной терапии иммунной тромбоцитопении (ИТП) по-прежнему широко обсуждается специалистами и является предметом оживленных дискуссий. Цель исследования: оценить эффективность высокогорной климатотерапии при хронической ИТП у детей за 5-летний период наблюдения после ежегодного лечения на высокогорной базе. Материалы и методы: В исследование включено 22 ребенка с хронической ИТП в возрасте от 3 до 14 лет, средний возраст — 6,30 ± 1,02 года, длительность заболевания 2-8 лет. Для лечения детей поднимали на высокогорную базу. Продолжительность лечения в высокогорье составляла 40 дней. Результаты: Из 22 детей, получивших 5 курсов высокогорной климатотерапии, у двоих наблюдали полную ремиссию в виде увеличения тромбоцитов более 100×109/л без кровоточивости. Объективный ответ в виде двукратного увеличения числа тромбоцитов, но менее 100×109/л без кровоточивости установлен у 18 детей, отсутствие эффекта было зарегистрировано у 2 детей. Заключение: Повторные курсы высокогорной климатотерапии способствуют улучшению клинической картины, существенному повышению числа тромбоцитов в периферической крови и достижению ремиссии при ИТП у детей. Background: Further development of basic treatment of immune thrombocytopenia (ITP) is still widely discussed by specialists and is the subject of lively discussions. Objectives: to assess the effi ciency of high-altitude climatotherapy in children with chronic ITP for a 5-year follow-up period after annual treatment at high-altitude base. Patients/Methods: The study included 22 children with chronic ITP from 3 to 14 years, the average age was 6.30 ± 1.02 years, and disease duration was 3-8 years. Children were raised to high-altitude base. Treatment duration was 40 days. Results: 22 children received 5 courses of high-altitude climatotherapy. Complete remission was observed in 2 patients with increasing of platelets more than 100×109/L without bleeding. In 18 children an objective response was found in the form of twofold increasing of platelets number, but less than 100×109/L without bleeding; no effect was recorded in 2 children. Conclusions: Repeated courses of high-altitude climatotherapy improve clinical characteristics, significantly increase the number of platelets in the peripheral blood and contribute to remission in children with ITP.

scholarly journals The use of an Alpine climate in the treatment of immune thrombocytopenic purpura (ITP) in children of the Kyrgyz Republic

2020 ◽  
Vol 11 (2) ◽  
pp. 2498-2504
Author(s):  
Mamatov Sagynali Murzaevich ◽  
Esengeldi Kyzy Aizhamal ◽  
Vityala Yethindra ◽  
Tugolbai Tagaev Jumabekovich ◽  
Arstanbekova Mira Arstanbekovna ◽  
...  
Keyword(s):  
Platelet Count ◽  
High Altitude ◽  
Sea Level ◽  
Immune Thrombocytopenia ◽  
Hematological Parameters ◽  
Complete Recovery ◽  
Kyrgyz Republic ◽  
Treatment Results ◽  
Thrombocytopenic Purpura ◽  
Chronic Immune Thrombocytopenia

The objective of the study is to evaluate the effectiveness of the use of alpine (high-altitude) climatotherapy in the chronic form of immune thrombocytopenia in children. The article presents the results of the treatment of immune thrombocytopenia in children during high altitude climatotherapy. For this type of treatment, the alpine climate of the Tuya-Ashu pass (3200 meters above sea level) in the Kyrgyz Republic used. A 40-day stay in the highlands contributes to the relief of hemorrhagic syndrome and a significant increase in platelet count. Evaluation of the treatment results showed that out of 32 children who received alpine (high-altitude) climatotherapy once, 2 achieved complete and 14 had partial remission. In 11 children, the improvement of clinical and hematological parameters was temporary, and the absence of effect recorded in 5 patients. 50% of children with chronic immune thrombocytopenia (ITP) responded positively to a single course of treatment. Repeated courses of treatment led only to an improvement in clinical and haematological parameters. In our study, we have a case of a complete recovery of a child with immune thrombocytopenia (ITP) after 5 treatments in high altitude conditions.

Use of high-altitude climate in therapy of childrenwith idiopathic thrombocytopenic purpura in Kyrgyz Republic

2018 ◽  
Author(s):  
С.М. Маматов ◽  
А.К. Эсенгелди ◽  
А.А. Махмануров
Keyword(s):  
Platelet Count ◽  
High Altitude ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Disease Duration ◽  
Hematological Parameters ◽  
Kyrgyz Republic ◽  
Duration Of Treatment ◽  
Thrombocytopenic Purpura ◽  
Hypoxia Exposure ◽  
The Subject

Введение. Вопрос о дальнейшем совершенствовании базисной терапии идиопатической тромбоцитопенической пурпуры (ИТП) по-прежнему широко обсуждается специалистами и является предметом оживленных дискуссий. Цель исследования: изучить динамику геморрагического синдрома и количества тромбоцитов у детей с ИТП в процессе высокогорной климатотерапии и оценить эффективность воздействия высокогорной гипоксии на течение болезни. Материалы и методы. В исследование включено 24 ребенка с хронической ИТП в возрасте от 5 до 14 лет (средний возраст — 10,25 ± 1,43 года) с длительностью заболевания от 4 до 8 лет. Для лечения детей поднимали на высокогорную базу Туя-Ашу (перевал Туя-Ашу, 3200 м над уровнем моря). Продолжительность лечения в высокогорье составляла 40 дней. Результаты. К концу срока пребывания в горах значительно уменьшались проявления геморрагического синдрома, полностью купировался анемический синдром, количество тромбоцитов достоверно увеличивалось с минимума 22,1 × 109/л до максимума 108,4 × 109/л. Заключение. Из 22 детей, получивших высокогорную климатотерапию, у 2 детей достигнута полная и у 15 — частичная ремиссия. У 4 детей улучшение клинико-гематологических показателей носило временный характер, и отсутствие эффекта зарегистрировано у 1 ребенка. Ремиссия достигнута у 77% больных детей. Introduction. Further improvement of the basic therapy of idiopathic thrombocytopenic purpura (ITP) is still widely discussedby specialists and is the subject of lively discussions. Aim: to study the dynamics of hemorrhagic syndrome and platelet count in children with ITP in the process of high-altitude climatotherapy and assess the eff ectiveness of high-altitude hypoxia exposure on the course of the disease. Materials and methods. The study included 24 children with chronic ITP aged 5 to 14 years (mean age — 10.25 ± 1.43 years) with disease duration from 4 to 8 years. For treatment children were raised to Tuya-Ashu high-altitude base (mountain pass Tuya Ashu, 3200 m above sea level). The duration of treatment in highlands was 40 days. Results. By the end of the treatment, the manifestations of hemorrhagic syndrome decreased signifi cantly, the anemic syndrome completely stopped, the platelet count increased significantly from minimum of 22.1 × 109/L to maximum of 108.4 × 109/L. Conclusion. High-altitude climatotherapy received 22 children, 2 children had complete remission and 15 — part remission. In 4 children the improvement of clinical and hematological parameters was temporal, and the absence of eff ect was registered in 1 child. Remission was achieved in 77% of ill children.

scholarly journals Nutrition characteristics and morbidity of adolescents (15-17 years) of Kyrgyz Republic

2017 ◽  
Vol 1 (Issue 1) ◽  
Author(s):  
Feruza Kochkorova ◽  
Marina Esenamanova ◽  
Raisa Atambaeva ◽  
Tatyana Tsivinskaya ◽  
Anarbek Erbaev
Keyword(s):  
High Altitude ◽  
Rural Population ◽  
Nutrition Status ◽  
Endocrine Disorders ◽  
Kyrgyz Republic ◽  
Food Ingredients ◽  
Healthy Nutrition ◽  
Increasing Trend ◽  
Excessive Consumption ◽  
Poverty Levels

Objective: In this study, we analyzed the nutrition status and morbidity of adolescents. Methods: The data for the current study were obtained from the database of National statistical committee of Kyrgyz Republic for the period of 2009-2014 on nutritional and energy value of nutrition of urban and rural population living in conditions of high-, middle- and low-altitudes. We compared obtained data with current recommended norms of consumption for food ingredients, energy and food products. - Results: Among adolescents of Kyrgyz Republic, residing especially in rural and high-altitude regions, there is an excessive consumption of fat and carbohydrates, and reduced consumption of protein. There is an increasing trend in prevalence of cardiovascular, respiratory, gastrointestinal and endocrine disorders, as well as malignancy for the period 2010-2014. Conclusion: The nutrition of adolescents is unbalanced and unhealthy, with diet composed mostly of carbohydrates and fat, lacking proteins and fruit and vegetables, accompanied by increased trend of morbidity, especially in rural and high-altitude regions. There is a need for interventions directed both to decrease poverty levels and increase awareness of healthy nutrition among adolescents and their families.

Contrast of Filament Bright Rims

1994 ◽  
Vol 144 ◽  
pp. 365-367
Author(s):  
E. V. Kononovich ◽  
O. B. Smirnova ◽  
P. Heinzel ◽  
P. Kotrč
Keyword(s):  
High Altitude ◽  
Line Profile ◽  
Line Center ◽  
Magnetic Structures ◽  
The Mean

AbstractThe Hα filtergrams obtained at Tjan-Shan High Altitude Observatory near Alma-Ata (Moscow University Station) were measured in order to specify the bright rims contrast at different points along the line profile (0.0; ± 0.25; ± 0.5; ± 0.75 and ± 1.0 Å). The mean contrast value in the line center is about 25 percent. The bright rims interpretation as the bases of magnetic structures supporting the filaments is suggested.

Clean Electron Microscope Substrate Films Used for Micrometeorite Collection and Study

1967 ◽  
Vol 25 ◽  
pp. 366-367
Author(s):  
D. M. Davies ◽  
R. Kemner ◽  
E. F. Fullam
Keyword(s):  
Thin Film ◽  
Electron Microscope ◽  
High Altitude ◽  
Amyl Acetate ◽  
Temperature Variations ◽  
Film Forming ◽  
Film Specimen ◽  
Particulate Contaminants

All serious electron microscopists at one time or another have been concerned with the cleanliness and freedom from artifacts of thin film specimen support substrates. This is particularly important where there are relatively few particles of a sample to be found for study, as in the case of micrometeorite collections. For the deposition of such celestial garbage through the use of balloons, rockets, and aircraft, the thin film substrates must have not only all the attributes necessary for use in the electron microscope, but also be able to withstand rather wide temperature variations at high altitude, vibration and shock inherent in the collection vehicle's operation and occasionally an unscheduled violent landing.Nitrocellulose has been selected as a film forming material that meets these requirements yet lends itself to a relatively simple clean-up procedure to remove particulate contaminants. A 1% nitrocellulose solution is prepared by dissolving “Parlodion” in redistilled amyl acetate from which all moisture has been removed.

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