Analysis of binary activity of Lactofiltrum

2020 ◽  
Vol 15 (5) ◽  
pp. 110-116
Author(s):  
V.G. Yankova ◽  
◽  
I.L. Udyanskaya ◽  
S.V. Grigoryeva ◽  
S.V. Gribanova ◽  
...  

Lactofiltrum is a combination drug, pharmacological action of which is associated with the properties of its active components, namely lignin and lactulose. The effects of Lactofiltrum include normalization of the colon microbiota, decrease in the intensity of endogenous toxic conditions, and possibility of using it in patients of different age (the drug is recommended for adults and children >1 year of age); these properties of Lactofiltrum explain its popularity among doctors of various specialties and patients. Objective. To analyze the binary activity of Lactofiltrum using the methods of qualitative and quantitative assessment of the adsorption and prebiotic actions. Materials and methods. Microphotographs of the morphology and surface texture of Lactofiltrum were obtained using the OlympusBX-51 optical microscope. The following methods were proposed for qualitative and quantitative assessment of the adsorption and prebiotic actions of Lactofiltrum: method of ‘visual qualitative assessment of the enterosorbent adsorption activity’ and reverse complexometric titration. Prebiotic activity was evaluated using microbiological methods. Conclusion. Our experimental study confirmed high adsorption and prebiotic activity of Lactofiltrum. Key words: adsorption and prebiotic activity, Lactofiltrum, microbiocenosis, drug for children older than 1 year of age

Resources ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 28 ◽  
Author(s):  
Paúl Carrión-Mero ◽  
Oscar Loor-Oporto ◽  
Héctor Andrade-Ríos ◽  
Gricelda Herrera-Franco ◽  
Fernando Morante-Carballo ◽  
...  

Zaruma is host to the ‘‘El Sexmo’’ tourist mine, the galleries of which extend below the city, and its exploitation dates back to precolonial times. The mining boom created important development in the area, but informal mining also emerged causing environmental issues and safety problems. This study presents a qualitative and quantitative assessment of the “El Sexmo” Tourist Mine in the context of its potential as a tourism geosite and mining site. The methodological stages included: (i) The process and systematization of the general mine information and its surroundings; (ii) the assessment of the geological and mining interest of the mine, through GAM and Brilha method; and (iii) description and proposal of action strategies through Delphi analysis and a Strengths, Weaknesses, Opportunities, and Threats (SWOT) matrix. Based on the results of the quantitative evaluation, the high values in the educational, scientific, and tourist aspects of the two applied methodologies, show the mine as a potential geosite and mining site with added cultural value. In addition, the quantitative assessment in correspondence with the qualitative analysis, allowed to propose improvement strategies to take advantage of the geological resources and mining identity of the area, as an alternative that strengthens the infrastructure of the mine and consolidates the geotouristic development of the area.


2021 ◽  
Vol 20 (5) ◽  
pp. 972-986
Author(s):  
Ol'ga V. MANDROSHCHENKO

Subject. The article addresses the issues of analysis and management of tax risks. Objectives. The purpose is to show the significance of certain methods for tax risk assessment, identify problems in tax risk management, propose measures to improve the management process. Methods. The study employs methods of induction, deduction, structural analysis, synthesis, comparison, schematic representation of relationships, statistical and economic, computational and constructive techniques. Results. The paper reveals that tax budgets are often non-realistic. There are no methods for qualitative and quantitative assessment of tax risks, regulatory support in the field of tax risk monitoring. Conclusions. The described stages of government’s tax risk management are interconnected. It is important to apply modern methods in tax budget preparation, to develop methods for quantitative and qualitative assessment of tax risks, to strengthen the monitoring of tax risks through designing an algorithm of its implementation.


Author(s):  
A. M. Orel

Introduction. A complete and systematic x-ray examination of all parts of the spine at the same time in elderly and senile people has not yet been carried out. On the other hand, radiography can identify spinal statics disorders that are typical for this category of people.The goal of research — describe the types of spinal statics disorders in young, elderly and senile people.Materials and methods. Digital radiography of all parts of the spine was performed in 103 patients with dorsopathies. The first group included 50 patients aged 60–74 years; men 16, women 34. The second study group included 21 patients aged 75–88 years, 6 men and 15 women. The third control group included 32 randomly selected people aged 21 to 45 years, 15 men and 17 women. The study belongs to the group of a posteriori x-ray processing and was carried out without the participation and additional irradiation of patients. On the screen of a personal computer, using the methods developed by the author, unified digital x-ray images of all parts of the spine of each patient were obtained. From the INION point, a vertical line occipital vertical descended along all the structures of the spine. Using the midpoint of the front and rear contour x-ray image of the vertebral body of the TII and TXII the front-rear axes were passed through until they intersect with the occipital vertical at the back and intersect with each other at the front. A qualitative assessment of the occipital vertical passage relative to the structures of the spine and a quantitative assessment of the angles of inclination and the angle of intersection of the front-rear axes of the TII and TXII vertebrae was carried out..Results. Five types (from 0 to 4) of spine statics were described and criteria for their qualitative and quantitative assessment were determined. It was found that in the control group, the most common type of spine statics was zero (0), while type 3 and 4 were not determined. In contrast, 3 and 4 types of spinal statics were most frequently observed in second group of patients. In the first group of patients, types 1 and 2 of spine statics were most often revealed, and other types of spine statics also occurred. Among the entire group of examined patients n=103 0 type of spinal statics disorder was detected in 27 (26,2 %) patients, type 1 in 35 (34 %), type 2 in 22 (21,3 %), type 3 in 11 (10,7 %) and type 4 in 8 patients (7,8 %). In patients with type 0 spinal statics, the angle of inclination of the front-rear axis of the TII vertebra was 16,67±8,49º, and of the TXII vertebra was 18,33±4,33º. In type 1 statics of the spine, the angle of inclination of the front-rear axis of the TII vertebra was 26,66±6,73º, and of the TXII vertebra was 21,17±4,92º. In type 2 spinal statics, the angle of inclination of the front-rear axis of the TII vertebra was 32,95± 6,82º, and of the TXII vertebra was 19,68±5,4º. In type III spinal statics, the angle of inclination of the front-rear axis of the TII vertebra was 41,09±9,22º, and of the TXII vertebra 26±11,05º. Type 4 statics of the spine were diagnosed in the presence of type 1–3 statics, in addition to which a pathological fracture or multiple compression fractures were detected in any part of the spine, or the vertebral bodies took the form of fish vertebrae.Conclusion. The study demonstrated the presence of characteristic prevailing types of spinal statics in young, elderly and senile people. These qualitative and quantitative criteria allow us to evaluate them. Based on the results of the study, an application for the utility patent of the Russian Federation «The Method for Evaluating Spine Statics», № 2019144992, priority dated 30.12.2019 was issued and filed. The identified qualitative and quantitative indicators can be used to develop criteria for determining the biological age of a person, which will contribute to improving the evidence-based approach to medicine. 


2019 ◽  
Vol 11 (20) ◽  
pp. 2374
Author(s):  
Mohammed Q. Alkhatib ◽  
Miguel Velez-Reyes

In this paper, an unsupervised unmixing approach based on superpixel representation combined with regional partitioning is presented. A reduced-size image representation is obtained using superpixel segmentation where each superpixel is represented by its mean spectra. The superpixel image representation is then partitioned into regions using quadtree segmentation based on the Shannon entropy. Spectral endmembers are extracted from each region that corresponds to a leaf of the quadtree and combined using clustering into endmember classes. The proposed approach is tested and validated using the HYDICE Urban and ROSIS Pavia data sets. Different levels of qualitative and quantitative assessments are performed based on the available reference data. The proposed approach is also compared with global (no-regional quadtree segmentation) and with pixel-based (no-superpixel representation) unsupervised unmixing approaches. Qualitative assessment was based primarily on agreement with spatial distribution of materials obtained from a reference classification map. Quantitative assessment was based on comparing classification maps generated from abundance maps using winner takes it all with a 50% threshold and a reference classification map. High agreement with the reference classification map was obtained by the proposed approach as evidenced by high kappa values (over 70%). The proposed approach outperforms global unsupervised unmixing approaches with and without superpixel representation that do not account for regional information. The agreement performance of the proposed approach is slightly better when compared to the pixel-based approached using quadtree segmentation. However, the proposed approach resulted in significant computational savings due to the use of the superpixel representation.


2021 ◽  
Author(s):  
Richard Joseph Licata ◽  
Piyush M Mehta ◽  
W. Kent Tobiska ◽  
Bruce R Bowman ◽  
Marcin Dominik Pilinski

Urology ◽  
2004 ◽  
Vol 64 (6) ◽  
pp. 1121-1126 ◽  
Author(s):  
Oliver W. Hakenberg ◽  
Susanne Fuessel ◽  
Katja Richter ◽  
Michael Froehner ◽  
Sven Oehlschlaeger ◽  
...  

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