COMPARATIVE HPLC STUDY OF RELEASE KINETICS OF THE COCRYSTALLIZED AS WELL AS MIXTURE OF ACTIVE PHARMACEUTICAL INGREDIENTS OF ASPIRIN, IBUPROFEN, INDOMETHACIN, DICLOFENAC SODIUM AND PARACETAMOL IN BODY FLUIDS

2017 ◽  
pp. 1-11
Author(s):  
Prof. Dr. Dhrubo Jyoti Sen
Keyword(s):  
Release Kinetics ◽  
Diclofenac Sodium ◽  
Body Fluids ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Kinetics Of ◽  
Hplc Study

scholarly journals Sulfanyl Porphyrazines with Morpholinylethyl Periphery—Synthesis, Electrochemistry, and Photocatalytic Studies after Deposition on Titanium(IV) Oxide P25 Nanoparticles

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2280
Author(s):  
Tomasz Koczorowski ◽  
Wojciech Szczolko ◽  
Anna Teubert ◽  
Tomasz Goslinski
Keyword(s):  
Diclofenac Sodium ◽  
2D Nmr ◽  
Oxide Nanoparticles ◽  
Electrochemical Studies ◽  
Macrocyclic Compounds ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Vis Spectroscopy ◽  
Singlet Oxygen Quencher ◽  
Nmr Techniques

The syntheses, spectral UV–Vis, NMR, and electrochemical as well as photocatalytic properties of novel magnesium(II) and zinc(II) symmetrical sulfanyl porphyrazines with 2-(morpholin-4-yl)ethylsulfanyl peripheral substituents are presented. Both porphyrazine derivatives were synthesized in cyclotetramerization reactions and subsequently embedded on the surface of commercially available P25 titanium(IV) oxide nanoparticles. The obtained macrocyclic compounds were broadly characterized by ESI MS spectrometry, 1D and 2D NMR techniques, UV–Vis spectroscopy, and subjected to electrochemical studies. Both hybrid materials, consisting of porphyrazine derivatives embedded on the titanium(IV) oxide nanoparticles’ surface, were characterized in terms of particle size and distribution. Next, they were subjected to photocatalytic studies with 1,3-diphenylisobenzofuran, a known singlet oxygen quencher. The applicability of the obtained hybrid material consisting of titanium(IV) oxide P25 nanoparticles and magnesium(II) porphyrazine derivative was assessed in photocatalytic studies with selected active pharmaceutical ingredients, such as diclofenac sodium salt and ibuprofen.

scholarly journals Effect of Plasticizer on Release Kinetics of Diclofenac Sodium Pellets Coated with Eudragit RS 30 D

2008 ◽  
Vol 9 (4) ◽  
pp. 1240-1246 ◽  
Author(s):  
Golam Kibria ◽  
Monzurul Amin Roni ◽  
Mohammad Shahriarul Absar ◽  
Reza-ul Jalil
Keyword(s):  
Release Kinetics ◽  
Diclofenac Sodium ◽  
Eudragit Rs ◽  
Kinetics Of

scholarly journals DETERMINATION OF RADIOLOGICAL PARAMETERS OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS USING WINXCOM SOFTWARE IN THE ENERGY RANGE 1KEV TO 100KEV

2021 ◽  
Vol 5 (5) ◽  
pp. 54-62
Author(s):  
Arome Aruwa ◽  
Philibus Musa Gyuk ◽  
Columbus Tobechukwu Eze ◽  
Suleiman Isah ◽  
Achor Mathias Ogwo ◽  
...  
Keyword(s):  
Energy Range ◽  
Electron Density ◽  
Attenuation Coefficient ◽  
Atomic Number ◽  
Diclofenac Sodium ◽  
Effective Atomic Number ◽  
Mass Attenuation Coefficient ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Mass Attenuation

The effective atomic number, electron density and mass attenuation coefficient of some selected active pharmaceutical ingredients such as Diclofenac Sodium, Femotidine, Alprazolam, Amiodar, Amiodarone, Ciprofloxacin, and Nimesulide have been calculated over the energy range from 1 keV to 100 GeV for total and partial photon interactions by using WinXCom. The obtained data shows that the change in mass attenuation coefficient and electron density varies with energy and chemical composition of the active pharmaceutical ingredients (API’s) in drugs. The results in the variation of photon interaction with energy and effective atomic number of the API’s in drug are shown in the logarithmic graphs.

scholarly journals Effect of Acrylic Polymers on the Physical Parameters and in vitro Release Kinetics of Diclofenac Sodium Sustained Release Pellets

1970 ◽  
Vol 42 (3) ◽  
pp. 239-248
Author(s):  
MS Absar ◽  
G Kibria ◽  
R Ul Jalil
Keyword(s):  
Release Kinetics ◽  
Diclofenac Sodium ◽  
Physical Parameters ◽  
Acrylic Polymers ◽  
Eudragit Rs ◽  
Zero Order Kinetics ◽  
Methacrylate Copolymer ◽  
Eudragit Rl ◽  
Kinetics Of

The aim of the present study is to investigate the effect of Ammonio Methacrylate Copolymer Type A (Eudragit RL 30 D) and Ammonio Methacrylate Copolymer Type B (Eudragit RS 30 D) on the release kinetics study of diclofenac sodium form coated pellets. Eudragit RS 30 D and Eudragit RL 30 D were added into the formulation at 5:1 ratio. Different percent of this polymeric combination was loaded on to the drug-loaded pellets. Loss on drying value as well as bulk density of coated pellets increase along with the increase in polymer level. It was found that the cumulative percent release of drug decreased with the increase of polymer load in all cases. From all formulations it was observed that the release of diclofenac sodium in 0.1N HCl media was very low (maximum 2.87 %) at first 2 hours. Better sustaining effect was found from Eudragit RS 30 D and Eudragit RL 30 D combinations. Drug was released linearly along with time throughout the whole dissolution process in phosphate buffer (pH 6.8) and it was also revealed that, in all cases the release of diclofenac sodium followed zero order kinetics. Key words: Diclofenac sodium, Eudragit RL 30 D, Eudragit RS 30 D, Aqueous coating, Physical parameters, Kinetics of drug release Bangladesh J. Sci. Ind. Res. 42(3), 239-248, 2007

Sign in / Sign up

Export Citation Format

Share Document