scholarly journals Analysis of risk factors of acute kidney injury in perioperative patients after lung transplantation

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Xiaoshu Liu ◽  
Jing Zhang ◽  
Yang Yang ◽  
Xiaobo Huang ◽  
Xiaoqin Zhang ◽  
...  
2020 ◽  
Vol 52 (3) ◽  
pp. 967-976 ◽  
Author(s):  
E. Atchade ◽  
S. Barour ◽  
A. Tran-Dinh ◽  
S. Jean-Baptiste ◽  
S. Tanaka ◽  
...  

2021 ◽  
Author(s):  
Nam Eun Kim ◽  
Chi Young Kim ◽  
Song Yee Kim ◽  
Ha Eun Kim ◽  
Jin Gu Lee ◽  
...  

Abstract Background After lung transplantation (LT), some patients are at risk of acute kidney injury (AKI), which is associated with worse outcomes and increased mortality. Method Among 161 patients who underwent LT at Severance hospital in Seoul, Korea from October 2012 to September 2017, 148 patients were retrospectively enrolled. Results 59 (39.8%) developed AKI within 1-month after LT. Stage I or II, and stage III AKI were recorded in 26 (17.5%) and 33 (22.2%), respectively. AKI III usually occurred within 7 days after transplantation (early vs. late AKI III, 72.5% vs 21.1%). Pre-operative anemia, units of red blood cells transfused during surgery, colistin intravenous infusion for treating multi drug resistant pathogens were independent risk factors for AKI development. Post-operative bleeding, grade 3 PGD within 72 hrs, and sepsis were more common in the AKI group. Patients with AKI III ([24/33] 72.7%) had significantly higher 1-year mortality than the no-AKI ([18/89] 20.2%), and AKI I or II group ([9/26] 34.6%), log-rank test, P < 0.001). Conclusion AKI was associated with worse post-operative outcome, 3-month, and 1-year mortality after LT. Severity of AKI was usually determined in early post op period after LT, so optimal post-operative management as well as recipients selection should be considered.


Renal Failure ◽  
2021 ◽  
Vol 43 (1) ◽  
pp. 535-542
Author(s):  
Wen-Wen Du ◽  
Xiao-Xing Wang ◽  
Dan Zhang ◽  
Wen-Qian Chen ◽  
Xiang-Lin Zhang ◽  
...  

2012 ◽  
Vol 29 ◽  
pp. 179
Author(s):  
J. García Suárez ◽  
L. Gajate ◽  
A. Villafranca ◽  
M. Maric ◽  
M. Galán ◽  
...  

2020 ◽  
Author(s):  
Ling Sang ◽  
Sibei Chen ◽  
Lingbo Nong ◽  
Yonghao Xu ◽  
Haichong Zheng ◽  
...  

Abstract Background To evaluate the incidence, risk factors, and prognosis of acute kidney injury (AKI) after lung transplantation (LTx). Methods Records of patients who underwent LTx in a single center were retrospectively reviewed. The prevalence of post-transplant AKI, the use of continuous renal replacement therapy (CRRT), and the risk factors for AKI were investigated. The impact of AKI and CRRT on short-term outcomes and long-term survival was measured. Results 148 patients were included with 67 cases developed post-operative AKI. 31 patients underwent CRRT; the percentage of CRRT was 6.2%, 0%, 10% and 86.2% in no-AKI, and stage 1, 2 and 3 AKI, respectively. Patients with AKI had significantly higher ICU mortality and in-hospital mortality. The 1-year post-LTx survival rate of patients with AKI was 47.8%, significantly lower than those without (74.1%). There was no difference in the 1-year survival rate of those with stage 1 and stage 2 AKI, but patients with stage 3 AKI showed the worst survival. Patients who underwent CRRT had an inferior survival outcome (9.7% vs. 76.1%, P < 0.05). We found that higher APACHE II score (OR 1.082, P = 0.009), and higher intraoperative fluid balance (OR 1.001, P = 0.012) were independent risk factors, and female (OR 2.539) and pulmonary hypertension (OR 2.869) were potential risk factors for post-LTx AKI. A prediction model integration of the above factors showed a good concordance with actual risks and had a C-index of 0.76 (95% CI, 0.66–0.87). Conclusion Severe AKI which needed CRRT had a negative impact on the short-term and long-term outcomes.


Sign in / Sign up

Export Citation Format

Share Document