scholarly journals A randomized controlled trial of low carbohydrate and low fat/high fiber diets for weight loss.

1986 ◽  
Vol 76 (11) ◽  
pp. 1293-1296 ◽  
Author(s):  
J A Baron ◽  
A Schori ◽  
B Crow ◽  
R Carter ◽  
J I Mann
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Low Fat ◽  
High Fiber ◽  
Randomized Controlled ◽  
Low Carbohydrate

A RANDOMIZED TRIAL OF A VERY LOW CARBOHYDRATE KETOGENIC DIET V/S LOW FAT/CALORIE RESTRICTED DIET FOR WEIGHT LOSS AMONG OVERWEIGHT/OBESE ADULTS

2021 ◽  
pp. 6-8
Author(s):  
Maitri Hathi ◽  
Sudesh Kumar ◽  
Himanshu Nagar
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Ketogenic Diet ◽  
Controlled Trial ◽  
Dietary Advice ◽  
Low Fat ◽  
Obese Adults ◽  
Randomized Controlled ◽  
Short Period ◽  
Low Carbohydrate

BACKGROUND: Ketogenic diet is now in trend. But very less researches were conducted in India to check signicant effects on weight loss of Ketogenic Diet among overweight/obese adults compared to calorie restricted Low Fat diet. OBJECTIVE:To compare the effect of Very Low Carbohydrate Ketogenic (VLCK) diet and energy restricted Low-Fat (LF) diets on weight loss in overweight/obese healthy adults. Design: An interventional randomized controlled trial of 6 months was initiated. PARTICIPANTS: 113 overweight/obese adults with a body mass index of 25 kg/m2 or greater; with no abnormalities and more than 20 years of age. INTERVENTION: Among 113 overweight/obese adults, we conducted a six-month randomized controlled trial of two sets of dietary advice, each providing approximately 12,00-1500 calories per day but differing in protein, ber, fat and carbohydrate content. RESULTS: We found that dieters given VLCK advice tended to lose more weight than those given a LF diet. CONCLUSION: For short period of time VLCK diet is more effective than conventional LF diet for weight loss. But for long term effects further studies are required.

scholarly journals Effects of Low-Fat, Mediterranean, or Low-Carbohydrate Weight Loss Diets on Serum Urate and Cardiometabolic Risk Factors - A Secondary Analysis of the Dietary Intervention Randomized Controlled Trial (DIRECT)

2020 ◽  
Author(s):  
Chio Yokose ◽  
Natalie McCormick ◽  
Sharan K. Rai ◽  
Na Lu ◽  
Gary Curhan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Weight Loss ◽  
Cardiometabolic Risk ◽  
Dietary Intervention ◽  
Controlled Trial ◽  
Serum Urate ◽  
Group Comparison ◽  
Low Fat ◽  
Randomized Controlled ◽  
Low Carbohydrate

Objectives: <a>Weight loss diets may reduce serum urate (SU) by lowering insulin resistance while providing cardiometabolic benefits, something urate-lowering drugs have not shown in trials. </a>We aim to examine the effects of weight loss diets on SU and cardiometabolic risk factors. <p>Research Design and Methods: Secondary study of the Dietary Intervention Randomized Controlled Trial (DIRECT) using stored samples from 235 participants with moderate obesity randomly assigned to low-fat, restricted-calorie (n=85), Mediterranean, restricted-calorie (n=76), or low-carbohydrate, non-restricted-calorie (n=74) diets. We examined SU changes at 6- and 24-months overall, and among those with hyperuricemia (SU³416 μmol/L), a relevant subgroup at risk for gout.</p> <p>Results: Among all participants, average SU decreases were 48 μmol/L at 6-months and 18 μmol/L at 24-months, with no differences between diets (p>0.05). Body weight, HDL-C, total cholesterol to HDL-C ratio, triglycerides, and insulin concentrations also improved in all three groups (p<0.05 at 6 months). Adjusting for covariates, changes in weight and fasting plasma insulin concentrations remained associated with SU changes (p<0.05). SU reductions among those with hyperuricemia were 113, 119, and 143 μmol/L at 6 months for low-fat, Mediterranean, and low-carbohydrate diets (all p for within-group comparison <0.001; p>0.05 for between-group comparisons), and 65, 77, and 83 μmol/L, respectively, at 24-months (all p for within-group comparison <0.01; p>0.05 for between-group comparisons).</p> <a>Conclusions</a>: <a>Non-purine-focused weight loss diets may simultaneously improve SU and cardiovascular risk factors, likely mediated by reducing adiposity and insulin resistance. </a>These dietary options could provide personalized pathways to suit patient comorbidity and preferences for adherence.

scholarly journals Effects of Low-Fat, Mediterranean, or Low-Carbohydrate Weight Loss Diets on Serum Urate and Cardiometabolic Risk Factors - A Secondary Analysis of the Dietary Intervention Randomized Controlled Trial (DIRECT)

2020 ◽  
Author(s):  
Chio Yokose ◽  
Natalie McCormick ◽  
Sharan K. Rai ◽  
Na Lu ◽  
Gary Curhan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Weight Loss ◽  
Cardiometabolic Risk ◽  
Dietary Intervention ◽  
Controlled Trial ◽  
Serum Urate ◽  
Group Comparison ◽  
Low Fat ◽  
Randomized Controlled ◽  
Low Carbohydrate

Objectives: <a>Weight loss diets may reduce serum urate (SU) by lowering insulin resistance while providing cardiometabolic benefits, something urate-lowering drugs have not shown in trials. </a>We aim to examine the effects of weight loss diets on SU and cardiometabolic risk factors. <p>Research Design and Methods: Secondary study of the Dietary Intervention Randomized Controlled Trial (DIRECT) using stored samples from 235 participants with moderate obesity randomly assigned to low-fat, restricted-calorie (n=85), Mediterranean, restricted-calorie (n=76), or low-carbohydrate, non-restricted-calorie (n=74) diets. We examined SU changes at 6- and 24-months overall, and among those with hyperuricemia (SU³416 μmol/L), a relevant subgroup at risk for gout.</p> <p>Results: Among all participants, average SU decreases were 48 μmol/L at 6-months and 18 μmol/L at 24-months, with no differences between diets (p>0.05). Body weight, HDL-C, total cholesterol to HDL-C ratio, triglycerides, and insulin concentrations also improved in all three groups (p<0.05 at 6 months). Adjusting for covariates, changes in weight and fasting plasma insulin concentrations remained associated with SU changes (p<0.05). SU reductions among those with hyperuricemia were 113, 119, and 143 μmol/L at 6 months for low-fat, Mediterranean, and low-carbohydrate diets (all p for within-group comparison <0.001; p>0.05 for between-group comparisons), and 65, 77, and 83 μmol/L, respectively, at 24-months (all p for within-group comparison <0.01; p>0.05 for between-group comparisons).</p> <a>Conclusions</a>: <a>Non-purine-focused weight loss diets may simultaneously improve SU and cardiovascular risk factors, likely mediated by reducing adiposity and insulin resistance. </a>These dietary options could provide personalized pathways to suit patient comorbidity and preferences for adherence.

PROP Nontaster Women Lose More Weight Following a Low-Carbohydrate Versus a Low-Fat Diet in a Randomized Controlled Trial

Obesity ◽  
2017 ◽  
Vol 25 (10) ◽  
pp. 1682-1690 ◽  
Author(s):  
Brenda Burgess ◽  
Hollie A. Raynor ◽  
Beverly J. Tepper
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Low Fat ◽  
Randomized Controlled ◽  
Low Fat Diet ◽  
Low Carbohydrate
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