Human Rhinovirus Infection Enhances the Th2 Environment in Allergic and Non-allergic Patients with Chronic Rhinosinusitis
Keyword(s):
Objectives. This study was conducted to determine whether patients with allergy might be more susceptible to human rhinovirus (HRV) infection and whether the effects of infection on the elicited immune responses are different in allergic and non-allergic patients with chronic rhinosinusitis (CRS). Methods. Uncinate process tissues were obtained from 61 chronic rhinosinusitis patients (of which, 39 had allergy and 22 did not) who were infected with HRV-16 using an air-liquid interface organ culture system. The expression levels of programmed cell death-ligand (PD-L)1, PD-L2, intracellular adhesion molecule 1 (ICAM-1), IFN-
Keyword(s):
1998 ◽
Vol 31
(2)
◽
pp. 102A
Keyword(s):
Keyword(s):
2011 ◽
Vol 20
(8)
◽
pp. 1244-1254
◽