Respiratory syncytial virus acute respiratory infections in ≥ 65-year-old adults in long-term care facilities in the Czech Republic

2021 ◽  
Vol 29 (3) ◽  
pp. 167-176
Author(s):  
Jiří Beran ◽  
Ana Ramirez Villaescusa ◽  
Raghavendra Devadiga ◽  
Thi Lien-Anh Nguyen ◽  
Olivier Gruselle ◽  
...  
2015 ◽  
Vol 10 (1) ◽  
pp. 34-36 ◽  
Author(s):  
Meghan T. Murray ◽  
Elizabeth Heitkemper ◽  
Olivia Jackson ◽  
Natalie Neu ◽  
Patricia Stone ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Mary Checivich ◽  
Shari Barlow ◽  
Peter Shult ◽  
Erik Residorf ◽  
Jonathan L. Temte

ObjectiveTo assess the feasibility of conducting respiratory virus surveillance for residents of long term care facilities (LTCF) using simple nasal swab specimens and to describe the virology of acute respiratory infections (ARI) in LCTFs.IntroductionAlthough residents of LTCFs have high morbidity and mortality associated with ARIs, there is very limited information on the virology of ARI in LTCFs.[1,2] Moreover, most virological testing of LCTF residents is reactive and is triggered by a resident meeting selected surveillance criteria. We report on incidental findings from a prospective trial of introducing rapid influenza diagnostic testing (RIDT) in ten Wisconsin LTCFs over a two-year period with an approach of testing any resident with ARI.MethodsAny resident with new onset of respiratory symptoms consistent with ARI had a nasal swab specimen collected for RIDT by nursing staff. Following processing for RIDT (Quidel Sofia Influenza A+B FIA), the residual swab was placed into viral transport medium and forwarded to the Wisconsin State Laboratory of Hygiene and tested for influenza using RT-PCR (IVD CDC Human Influenza Virus Real-Time RT-PCR Diagnostic Panel), and for 17 viruses (Luminex NxTAG Respiratory Pathogen Panel [RPP]). The numbers of viruses in each of 7 categories [influenza A (FluA ), influenza B (FluB), coronaviruses (COR), human metapneumovirus (hMPV), parainfluenza (PARA), respiratory syncytial virus (RSV) and rhinovirus/enterovirus (R/E)], across the two years were compared using chi-square.ResultsTotals of 164 and 190 specimens were submitted during 2016-2017 and 2017-2018, respectively. RPP identified viruses in 56.2% of specimens, with no difference in capture rate between years (55.5% vs. 56.8%). Influenza A (21.5%), influenza B (16.5%), RSV (19.0%) and hMPV (16.5%) accounted for 73.5% of all detections, while coronaviruses (15.5%), rhino/enteroviruses (8.5%) and parainfluenza (2.5%) were less common. Specific distribution of viruses varied significantly across the two years (Table: X2=48.1, df=6; p<0.001).ConclusionsSurveillance in LTCFs using nasal swabs collected for RIDT is highly feasible and yields virus identification rates similar to those obtained in clinical surveillance of ARI with collection of nasopharyngeal specimens by clinicians and those obtained in a school-based surveillance project of ARI with collection of combined nasal and oropharyngeal specimens collected by trained research assistants. Significant differences in virus composition occurred across the two study years. RSV varied little between years while hMPV demonstrated wide variation. Simple approaches to surveillance may provide a more comprehensive assessment of respiratory viruses in LTCF settings.References(1) Uršič T, Gorišek Miksić N, Lusa L, Strle F, Petrovec M. Viral respiratory infections in a nursing home: a six-month prospective study. BMC Infect Dis. 2016; 16: 637. Published online 2016 Nov 4. doi: 10.1186/s12879-016-1962-8(2) Masse S, Capai L, Falchi A. Epidemiology of Respiratory Pathogens among Elderly Nursing Home Residents with Acute Respiratory Infections in Corsica, France, 2013–2017. Biomed Res Int. 2017; 2017: 1423718. Published online 2017 Dec 17. doi: 10.1155/2017/1423718


2021 ◽  
Vol 1 (7) ◽  
Author(s):  
Keeley Farrell ◽  
Jennifer Horton

The results of 1 systematic review suggest that supplementation with vitamin D may provide some benefit for cancer-related mortality in older adults. It is unclear whether there is a benefit of vitamin D supplementation for all-cause mortality; however, no benefit was found for cardiovascular disease mortality, cardiovascular disease events, or cancer incidence. There is limited and mixed evidence on the effectiveness of vitamin D supplementation for dementia and mild cognitive impairment in older adults. The results of 1 systematic review suggest that vitamin D supplementation may provide protection against acute respiratory infections in the overall population; however, this result was not significant in the subgroup of patients older than 65 years. No evidence-based guidelines were identified regarding vitamin D supplementation for the prevention and/or treatment of cardiovascular disease, cancer, and other conditions in elderly patients residing in long-term care facilities.


2020 ◽  
Vol 28 (4) ◽  
pp. 200-203
Author(s):  
Nancy Barrett ◽  
Lisa Bailey ◽  
Florence Ford ◽  
Monique Thorne ◽  
Nancy Azab ◽  
...  

2020 ◽  
Vol 48 (12) ◽  
pp. 1474-1477 ◽  
Author(s):  
Sibyl Wilmont ◽  
Natalie Neu ◽  
Alexandra Hill-Ricciuti ◽  
Luis Alba ◽  
Mila M. Prill ◽  
...  

Author(s):  
Lisa Saiman ◽  
Sibyl Wilmont ◽  
Alexandra Hill-Ricciuti ◽  
Meaghan Jain ◽  
Emily Collins ◽  
...  

Abstract We surveyed clinical staff and on-site teachers working at pediatric long-term care facilities regarding prevention and control of acute respiratory infections and influenza in staff and residents. We uncovered knowledge gaps, particularly among teachers and clinical staff working &lt;5 years at sites, thereby elucidating areas for targeted staff education.


2021 ◽  
Vol 4 (6) ◽  
pp. e2111806
Author(s):  
Elliott Bosco ◽  
Robertus van Aalst ◽  
Kevin W. McConeghy ◽  
Joe Silva ◽  
Patience Moyo ◽  
...  

2011 ◽  
Vol 140 (3) ◽  
pp. 400-406 ◽  
Author(s):  
A. MANZUR ◽  
E. RUIZ DE GOPEGUI ◽  
M. DOMINGUEZ ◽  
D. MARISCAL ◽  
L. GAVALDA ◽  
...  

SUMMARYMethicillin-resistantStaphylococcus aureus(MRSA) is highly prevalent in Spanish hospitals and community long-term-care facilities (LTCFs). This longitudinal study was performed in community LTCFs to determine whether MRSA colonization is associated with MRSA infections and overall mortality. Nasal and decubitus ulcer cultures were performed every 6 months for an 18-month period on 178 MRSA-colonized residents (86 490 patient-days) and 196 non-MRSA carriers (97 470 patient-days). Fourteen residents developed MRSA infections and 10 of these were skin and soft tissue infections. Two patients with respiratory infections required hospitalization. The incidence rate of MRSA infection was 0·12/1000 patient-days in MRSA carriers and 0·05/1000 patient-days in non-carriers (P=0·46). No difference in MRSA infection rate was found according to the duration of MRSA colonization (P=0·69). The mortality rate was 20·8% in colonized residents and 16·8% in non-carriers; four residents with MRSA infection died. Overall mortality was statistically similar in both cohorts. Our results suggest that despite a high prevalence of MRSA colonization in LTCFs, MRSA infections are neither frequent nor severe while colonized residents remain at the facility. The epidemiological impact of an MRSA reservoir is more relevant than the clinical impact of this colonization for an individual resident and supports current recommendations to control MRSA spread in community LTCFs.


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