scholarly journals The Validity and Reliability of the Patient Health Questionnaire-9 in Screening for Post-stroke Depression

2019 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  
Keyword(s):  
Depressive Disorder ◽  
Positive Likelihood Ratio ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Validity And Reliability ◽  
Stroke Patients ◽  
Psychiatric Interview ◽  
Post Stroke ◽  
Patient Health ◽  
Post Stroke Depression

Abstract Depression affects about 30% of stroke survivors within five years. Timely diagnosis and management of post-stroke depression (PSD) facilitate motor recovery and improve independence. The original version of the Patient Health Questionnaire-9 (PHQ-9) is one of the good screening tools for post-stroke depression. As yet, no validation studies of depression in Thai stroke patients by the Thai PHQ-9. Methods: The objectives of the study were to determine the criterion validity and reliability of the Thai PHQ-9 in screening for post-stroke depression by comparing with a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the Thai PHQ-9. The gold standard was a psychiatric interview leading to a DSM-5 diagnosis of depressive disorder. The summed-scored based diagnosis of depressive disorder with the PHQ-9 was obtained. The validity and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: 115 stroke patients (mean age, 64 + 10 years) were enrolled. The mean PHQ-9 score was 5.2 + 4.8. Using DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The Thai PHQ-9 had satisfactory internal consistency (Cronbach’s alpha, 0.78). The algorithm-based diagnosis of the Thai PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a summed-scored based diagnosis, an optimal cut-off score of six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI, 0.78–0.96). Conclusions: The PHQ-9 (Thai language version) has acceptable psychometric properties for screening for post-stroke depression, with a recommended cut-off score of 6 or greater in a Thai population. Keywords: depression, Patient Health Questionnaire-9, reliability, screening, stroke, Thai, validity

scholarly journals The Validity and Reliability of the Patient Health Questionnaire-9 in Screening for Post-Stroke Depression

2020 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  
Keyword(s):  
Depressive Disorder ◽  
Gold Standard ◽  
Positive Likelihood Ratio ◽  
Validity And Reliability ◽  
Stroke Patients ◽  
Psychiatric Interview ◽  
Post Stroke ◽  
Dsm 5 ◽  
Patient Health ◽  
Post Stroke Depression

Abstract Background: Depression affects about 30% of stroke survivors within five years. Timely diagnosis and management of post-stroke depression facilitate motor recovery and improve independence. The original version of the Patient Health Questionnaire-9 (PHQ-9) is recognized as a good screening tool for post-stroke depression. However, no validation studies have been undertaken for the use of the Thai PHQ-9 in screening for depression among Thai stroke patients. Methods: The objectives were to determine the criterion validity and reliability of the Thai PHQ-9 in screening for post-stroke depression by comparing its results with those of a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the Thai PHQ-9. The gold standard was a psychiatric interview leading to a DSM-5 diagnosis of depressive disorder. The summed-scored-based diagnosis of depressive disorder with the PHQ-9 was obtained. Validity and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: In all, 115 stroke patients with a mean age of 64 years (SD: 10 years) were enrolled. The mean PHQ-9 score was 5.2 (SD: 4.8). Using the DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The Thai PHQ-9 had satisfactory internal consistency (Cronbach’s alpha: 0.78). The algorithm-based diagnosis of the Thai PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a summed-scored-based diagnosis, an optimal cut-off score of six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI: 0.78–0.96). Conclusions: The Thai PHQ-9 has acceptable psychometric properties for screening for post-stroke depression, with a recommended cut-off score of ≥ 6 for a Thai population.

Abstract 118: Predictors of Post-Stroke Depression in Ischemic Stroke Patients using the Patient Health Questionnaire-9

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Lauren E Fournier ◽  
Xu Zhang ◽  
Esther Bonojo ◽  
Mary Love ◽  
Jennifer Sanner ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Stroke Patients ◽  
Post Stroke ◽  
Patient Health ◽  
Post Stroke Depression

scholarly journals The Validity and Reliability of the Patient Health Questionnaire-9 in Screening for Poststroke Depression

2019 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  
Keyword(s):  
Major Depression ◽  
Predictive Value ◽  
Gold Standard ◽  
Positive Likelihood Ratio ◽  
Health Questionnaire ◽  
Validity And Reliability ◽  
Poststroke Depression ◽  
Stroke Patients ◽  
Psychiatric Interview ◽  
Patient Health

Abstract Background: Poststroke depression affects about 30% of stroke survivors within five years. Timely diagnosis and management facilitate motor recovery and improve independence. The Patient Health Questionnaire-9 (PHQ-9) is one of the good screening tools for poststroke depression. High validity and reliability of the PHQ-9 is clinically essential. Methods: The objectives of the study were to determine the criterion validity and reliability of the PHQ-9 (Thai version) in screening for poststroke depression by comparing with a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the PHQ-9. The gold standard was a psychiatric interview for major depression. Diagnosis of major depression according to PHQ-9 can be categorical algorithm based and summed score based. The validity of these 2 ways of diagnosis and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: Enrolled were 115 stroke patients (mean age, 64 + 10 years). The mean PHQ-9 score was 5.2 + 4.8. Using DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The PHQ-9 had satisfactory internal consistency (Cronbach’s alpha, 0.78). The categorical algorithm of the PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a continuous measure, an optimal cut-off score of ≥ six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI, 0.78–0.96). Conclusions: The PHQ-9 has acceptable psychometric properties for screening for poststroke depression, with a recommended cut-off score of ≥ six.

Patient health questionnaire-15 (PHQ-15) to distinguish bipolar II disorder from major depressive disorder

2020 ◽  
Vol 290 ◽  
pp. 113026 ◽  
Author(s):  
Da-Liang Sun ◽  
Qing-He Liu ◽  
Mei-Juan Li ◽  
Yuan Yang ◽  
Ran Zhang ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Major Depressive ◽  
Bipolar Ii Disorder ◽  
Bipolar Ii ◽  
Patient Health

scholarly journals Validation of the Patient Health Questionnaire-9 for Major Depressive Disorder in the Occupational Health Setting

2015 ◽  
Vol 26 (2) ◽  
pp. 237-244 ◽  
Author(s):  
D. Volker ◽  
M. C. Zijlstra-Vlasveld ◽  
E. P. M. Brouwers ◽  
W. A. Homans ◽  
W. H. M. Emons ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Occupational Health ◽  
Depressive Disorder ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Major Depressive ◽  
Patient Health ◽  
Occupational Health Setting

scholarly journals Utilizing a Personal Smartphone Custom App to Assess the Patient Health Questionnaire-9 (PHQ-9) Depressive Symptoms in Patients With Major Depressive Disorder

2015 ◽  
Vol 2 (1) ◽  
pp. e8 ◽  
Author(s):  
John Torous ◽  
Patrick Staples ◽  
Meghan Shanahan ◽  
Charlie Lin ◽  
Pamela Peck ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Low Cost ◽  
Time Of Day ◽  
Patient Health Questionnaire ◽  
Therapeutic Monitoring ◽  
Depression Symptoms ◽  
Health Questionnaire ◽  
Major Depressive ◽  
Patient Health

Background Accurate reporting of patient symptoms is critical for diagnosis and therapeutic monitoring in psychiatry. Smartphones offer an accessible, low-cost means to collect patient symptoms in real time and aid in care. Objective To investigate adherence among psychiatric outpatients diagnosed with major depressive disorder in utilizing their personal smartphones to run a custom app to monitor Patient Health Questionnaire-9 (PHQ-9) depression symptoms, as well as to examine the correlation of these scores to traditionally administered (paper-and-pencil) PHQ-9 scores. Methods A total of 13 patients with major depressive disorder, referred by their clinicians, received standard outpatient treatment and, in addition, utilized their personal smartphones to run the study app to monitor their symptoms. Subjects downloaded and used the Mindful Moods app on their personal smartphone to complete up to three survey sessions per day, during which a randomized subset of PHQ-9 symptoms of major depressive disorder were assessed on a Likert scale. The study lasted 29 or 30 days without additional follow-up. Outcome measures included adherence, measured by the percentage of completed survey sessions, and estimates of daily PHQ-9 scores collected from the smartphone app, as well as from the traditionally administered PHQ-9. Results Overall adherence was 77.78% (903/1161) and varied with time of day. PHQ-9 estimates collected from the app strongly correlated (r=.84) with traditionally administered PHQ-9 scores, but app-collected scores were 3.02 (SD 2.25) points higher on average. More subjects reported suicidal ideation using the app than they did on the traditionally administered PHQ-9. Conclusions Patients with major depressive disorder are able to utilize an app on their personal smartphones to self-assess their symptoms of major depressive disorder with high levels of adherence. These app-collected results correlate with the traditionally administered PHQ-9. Scores recorded from the app may potentially be more sensitive and better able to capture suicidality than the traditional PHQ-9.

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