scholarly journals The Validity and Reliability of the Patient Health Questionnaire-9 in Screening for Poststroke Depression

2019 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  

Abstract Background: Poststroke depression affects about 30% of stroke survivors within five years. Timely diagnosis and management facilitate motor recovery and improve independence. The Patient Health Questionnaire-9 (PHQ-9) is one of the good screening tools for poststroke depression. High validity and reliability of the PHQ-9 is clinically essential. Methods: The objectives of the study were to determine the criterion validity and reliability of the PHQ-9 (Thai version) in screening for poststroke depression by comparing with a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the PHQ-9. The gold standard was a psychiatric interview for major depression. Diagnosis of major depression according to PHQ-9 can be categorical algorithm based and summed score based. The validity of these 2 ways of diagnosis and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: Enrolled were 115 stroke patients (mean age, 64 + 10 years). The mean PHQ-9 score was 5.2 + 4.8. Using DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The PHQ-9 had satisfactory internal consistency (Cronbach’s alpha, 0.78). The categorical algorithm of the PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a continuous measure, an optimal cut-off score of ≥ six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI, 0.78–0.96). Conclusions: The PHQ-9 has acceptable psychometric properties for screening for poststroke depression, with a recommended cut-off score of ≥ six.

2020 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  

Abstract Background: Depression affects about 30% of stroke survivors within five years. Timely diagnosis and management of post-stroke depression facilitate motor recovery and improve independence. The original version of the Patient Health Questionnaire-9 (PHQ-9) is recognized as a good screening tool for post-stroke depression. However, no validation studies have been undertaken for the use of the Thai PHQ-9 in screening for depression among Thai stroke patients. Methods: The objectives were to determine the criterion validity and reliability of the Thai PHQ-9 in screening for post-stroke depression by comparing its results with those of a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the Thai PHQ-9. The gold standard was a psychiatric interview leading to a DSM-5 diagnosis of depressive disorder. The summed-scored-based diagnosis of depressive disorder with the PHQ-9 was obtained. Validity and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: In all, 115 stroke patients with a mean age of 64 years (SD: 10 years) were enrolled. The mean PHQ-9 score was 5.2 (SD: 4.8). Using the DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The Thai PHQ-9 had satisfactory internal consistency (Cronbach’s alpha: 0.78). The algorithm-based diagnosis of the Thai PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a summed-scored-based diagnosis, an optimal cut-off score of six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI: 0.78–0.96). Conclusions: The Thai PHQ-9 has acceptable psychometric properties for screening for post-stroke depression, with a recommended cut-off score of ≥ 6 for a Thai population.


2019 ◽  
Author(s):  
Piyapat Dajpratham ◽  
Panate Pukrittayakamee ◽  
Wanlop Atsariyasing ◽  
Kamonporn Wannarit ◽  
Jariya Boonhong ◽  
...  

Abstract Depression affects about 30% of stroke survivors within five years. Timely diagnosis and management of post-stroke depression (PSD) facilitate motor recovery and improve independence. The original version of the Patient Health Questionnaire-9 (PHQ-9) is one of the good screening tools for post-stroke depression. As yet, no validation studies of depression in Thai stroke patients by the Thai PHQ-9. Methods: The objectives of the study were to determine the criterion validity and reliability of the Thai PHQ-9 in screening for post-stroke depression by comparing with a psychiatric interview as the gold standard. First-ever stroke patients aged ≥ 45 years with a stroke duration 2 weeks–2 years were administered the Thai PHQ-9. The gold standard was a psychiatric interview leading to a DSM-5 diagnosis of depressive disorder. The summed-scored based diagnosis of depressive disorder with the PHQ-9 was obtained. The validity and reliability analyses, and a receiver operating characteristic curve analysis, were performed. Results: 115 stroke patients (mean age, 64 + 10 years) were enrolled. The mean PHQ-9 score was 5.2 + 4.8. Using DSM-5 criteria, 23 patients (20%) were diagnosed with depressive disorder. The Thai PHQ-9 had satisfactory internal consistency (Cronbach’s alpha, 0.78). The algorithm-based diagnosis of the Thai PHQ-9 had low sensitivity (0.52) but very high specificity (0.94) and positive likelihood ratio (9.6). Used as a summed-scored based diagnosis, an optimal cut-off score of six revealed a sensitivity of 0.87, specificity of 0.75, positive predictive value of 0.46, negative predictive value of 0.95, and positive likelihood ratio of 3.5. The area under the curve was 0.87 (95% CI, 0.78–0.96). Conclusions: The PHQ-9 (Thai language version) has acceptable psychometric properties for screening for post-stroke depression, with a recommended cut-off score of 6 or greater in a Thai population. Keywords: depression, Patient Health Questionnaire-9, reliability, screening, stroke, Thai, validity


Author(s):  
Lauren E. Fournier ◽  
Jennifer E. Sanner Beauchamp ◽  
Xu Zhang ◽  
Esther Bonojo ◽  
Mary Love ◽  
...  

2016 ◽  
Vol 184 (9) ◽  
pp. 636-643 ◽  
Author(s):  
Michael Y. Ni ◽  
Tom K. Li ◽  
Herbert Pang ◽  
Brandford H. Y. Chan ◽  
Betty Y. Yuan ◽  
...  

Abstract Despite the extensive history of social movements around the world, the evolution of population mental health before, during, and after a social movement remains sparsely documented. We sought to assess over time the prevalence of depressive symptoms during and after the Occupy Central movement in Hong Kong and to examine the associations of direct and indirect exposures to Occupy Central with depressive symptoms. We longitudinally administered interviews to 909 adults who were randomly sampled from the population-representative FAMILY Cohort at 6 time points from March 2009 to March 2015: twice each before, during, and after the Occupy Central protests. The Patient Health Questionnaire-9 was used to assess depressive symptoms and probable major depression (defined as Patient Health Questionnaire-9 score ≥10). The absolute prevalence of probable major depression increased by 7% after Occupy Central, regardless of personal involvement in the protests. Higher levels of depressive symptoms were associated with online and social media exposure to protest-related news (incidence rate ratio (IRR) = 1.28, 95% confidence interval (CI): 1.06, 1.55) and more frequent Facebook use (IRR = 1.38, 95% CI: 1.12, 1.71). Higher levels of intrafamilial sociopolitical conflict was associated with more depressive symptoms (IRR = 1.05, 95% CI: 1.01, 1.09). The Occupy Central protests resulted in substantial and sustained psychological distress in the community.


Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Lauren E Fournier ◽  
Xu Zhang ◽  
Esther Bonojo ◽  
Mary Love ◽  
Jennifer Sanner ◽  
...  

Diagnostica ◽  
2004 ◽  
Vol 50 (4) ◽  
pp. 171-181 ◽  
Author(s):  
Kerstin Gräfe ◽  
Stephan Zipfel ◽  
Wolfgang Herzog ◽  
Bernd Löwe

Zusammenfassung. Ziel dieser Studie ist die Validierung der deutschen Version des “Patient Health Questionnaire (PHQ-D)“. Der PHQ wurde zum praktikablen Screening psychischer Störungen für die Primärmedizin entwickelt und erfasst direkt die diagnostischen Kriterien des DSM-IV. N = 357 allgemeinmedizinische/internistische Patienten und N = 171 psychosomatische Patienten wurden mit dem PHQ-D und dem Strukturierten Klinischen Interview für DSM-IV (SKID-I) untersucht, wobei das SKID-I als diagnostischer Goldstandard diente. Ärzte und Patienten wurden zur Akzeptanz des PHQ-D befragt. Eine ausgezeichnete Kriteriumsvalidität des PHQ-D zeigte sich insbesondere bei der Diagnose der Major Depression, wo die Sensitivität für die medizinische Stichprobe bei 95% und die Spezifität bei 86% lag. Gute teststatistische Werte ergaben sich u.a. auch für die Panikstörung. Die Anwendung des PHQ-D wurde von jeweils mehr als 90% der Patienten und Ärzte gut akzeptiert. Mit dem PHQ-D liegt ein praktikables, valides und gut akzeptiertes Instrument zur Anwendung in Forschung und klinischer Praxis vor. Sein Einsatz kann zur verbesserten Versorgung psychischer Störungen beitragen.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Fikru Tsehayneh ◽  
Abenet Tafesse

Background. There is limited information and research carried out regarding the prevalence of poststroke depression (PSD) in the study area. Psychiatric disorders complicate a significant proportion of patients suffering from stroke. This of course have a great negative impact on our knowledge about poststroke depression in Ethiopia, and poststroke depression complicates a significant number of stroke patients and their rehabilitation. Methods. A cross-sectional study on all patients aged above 18 years and diagnosed with stroke in the past two years who attended the neurology follow-up clinics of Tikur Anbessa Specialized Hospital (TASH) and Zewditu Memorial Hospital (ZMH) was done by using a structured questionnaire containing Patient Health Questionnaire-9 (PHQ-9) depression screening tool. Result. Of 84 patients who were eligible for the study, 32.2% of patients have depressive symptoms. Women (OR 0.001, 95% CI 0.12–0.87) and aphasic patients (OR 0.034, 95% CI 0.19–1.27) were more likely to have depressive symptoms. Conclusion. Depressive symptoms after stroke are common in Ethiopian patients. Our study demonstrates female and aphasic patients are more likely to screen positive for PSD. Hence, screening all poststroke patients with different screening tools is practical, and further studies are needed to assess the validity of these screening tools and also to assess PSD as a predictor of stroke outcome.


2013 ◽  
Vol 5 (2) ◽  
pp. 61-68 ◽  
Author(s):  
Shulin Chen ◽  
Yu Fang ◽  
Helen Chiu ◽  
Hainan Fan ◽  
Tao Jin ◽  
...  

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