Impact of early and timely screening of preemies on the development of retinopathy of prematurity (ROP): An urban-semi urban comparative study.

Abstract Background: To study and analyse the factors affecting the proportion of retinopathy of prematurity (ROP) distribution between the urban and semi-urban regions in North India. Methods: Retrospective, observational, cross-sectional study. All babies referred for ROP examination by paediatricians or other general ophthalmologists between 2013 – 2016 were included in the study. Demographic, clinical and treatment related findings were recorded. Results: Five hundred and fifty-eight (467: urban & 91: semi urban) babies were examined for ROP. The mean birth weight in the urban and semi-urban setting was 1348.6 ± 395.21 gm and 1703.77 ± 401.76 gm respectively. The mean gestational age was 30.99 ± 2.93 weeks and 30.73 ± 2.08 weeks in the urban and semi-urban cohorts respectively. The average time for first ophthalmic examination following birth was 23.82 ± 13.69 (range: 3-77) days in the urban and 101.16 ± 238.26 (range: 13- 330) days in the semi-urban setting. 94% of the babies completed all screening examination visits. Any ROP was identified in 11.6% and 33.0% of the urban and semi-urban cohorts respectively; Type 1 was detected in 7.5% of urban babies and 23.1% of semi-urban babies Conclusion: Differences in the proportion of babies developing any ROP and Type 1 ROP between the semi-urban and urban groups is likely due to selection bias, as a high proportion of semi-urban babies did not attend for examination or failed to complete all the examinations necessary. This was particularly true for females. More needs to be done to increase access to regular, systematic screening of preterm babies within neonatal units.

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Examination of preterm babies for ROP referred to an eye department from an urban and semi-urban neonatal intensive care unit: implications for practice.

10.21203/rs.2.9416/v3 ◽

2019 ◽

Author(s):

Ramesh Venkatesh ◽

Prachi Abhishek Dave ◽

Prachi Gurav ◽

Manisha Agarwal ◽

Mamta Jajoo ◽

...

Keyword(s):

Neonatal Intensive Care ◽

Cross Sectional Study ◽

Urban Setting ◽

North India ◽

Cross Sectional ◽

Systematic Screening ◽

Factors Affecting ◽

Preterm Babies ◽

The Mean

Abstract Background: To study and analyse the factors affecting the proportion of retinopathy of prematurity (ROP) distribution between the urban and semi-urban regions in North India. Methods: Retrospective, observational, cross-sectional study. All babies referred for ROP examination by paediatricians or other general ophthalmologists between 2013 – 2016 were included in the study. Demographic, clinical and treatment related findings were recorded. Results: Five hundred and fifty-eight (467: urban & 91: semi urban) babies were examined for ROP. The mean birth weight in the urban and semi-urban setting was 1348.6 ± 395.21 gm and 1703.77 ± 401.76 gm respectively. The mean gestational age was 30.99 ± 2.93 weeks and 30.73 ± 2.08 weeks in the urban and semi-urban cohorts respectively. The average time for first ophthalmic examination following birth was 23.82 ± 13.69 (range: 3-77) days in the urban and 101.16 ± 238.26 (range: 13- 330) days in the semi-urban setting. 94% of the babies completed all screening examination visits. Any ROP was identified in 11.6% and 33.0% of the urban and semi-urban cohorts respectively; Type 1 was detected in 7.5% of urban babies and 23.1% of semi-urban babies Conclusion: Differences in the proportion of babies developing any ROP and Type 1 ROP between the semi-urban and urban groups is likely due to selection bias, as a high proportion of semi-urban babies did not attend for examination or failed to complete all the examinations necessary. This was particularly true for females. More needs to be done to increase access to regular, systematic screening of preterm babies within neonatal units.

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Examination of preterm babies for ROP referred to an eye department from an urban and semi-urban neonatal intensive care unit: implications for practice.

10.21203/rs.2.9416/v5 ◽

2019 ◽

Author(s):

Ramesh Venkatesh ◽

Prachi Abhishek Dave ◽

Prachi Gurav ◽

Manisha Agarwal ◽

Mamta Jajoo ◽

...

Keyword(s):

Neonatal Intensive Care ◽

Cross Sectional Study ◽

Urban Setting ◽

North India ◽

Cross Sectional ◽

Systematic Screening ◽

Factors Affecting ◽

Preterm Babies ◽

The Mean

Abstract Background: To study and analyse the factors affecting the proportion of retinopathy of prematurity (ROP) distribution between the urban and semi-urban regions in North India. Methods: Retrospective, observational, cross-sectional study. All babies referred for ROP examination by paediatricians or other general ophthalmologists between 2013 – 2016 were included in the study. Demographic, clinical and treatment related findings were recorded. Results: Five hundred and fifty-eight (467: urban & 91: semi urban) babies were examined for ROP. The mean birth weight in the urban and semi-urban setting was 1348.6 ± 395.21 gm and 1703.77 ± 401.76 gm respectively. The mean gestational age was 30.99 ± 2.93 weeks and 30.73 ± 2.08 weeks in the urban and semi-urban cohorts respectively. The average time for first ophthalmic examination following birth was 23.82 ± 13.69 (range: 3-77) days in the urban and 101.16 ± 238.26 (range: 13- 330) days in the semi-urban setting. 94% of the babies completed all screening examination visits. Any ROP was identified in 11.6% and 33.0% of the urban and semi-urban cohorts respectively; Type 1 was detected in 7.5% of urban babies and 23.1% of semi-urban babies Conclusion: Differences in the proportion of babies developing any ROP and Type 1 ROP between the semi-urban and urban groups is likely due to selection bias, as a high proportion of semi-urban babies did not attend for examination or failed to complete all the examinations necessary. This was particularly true for females. More needs to be done to increase access to regular, systematic screening of preterm babies within neonatal units.

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Examination of preterm babies for ROP referred to an eye department from an urban and semi-urban neonatal intensive care unit: implications for practice.

10.21203/rs.2.9416/v4 ◽

2019 ◽

Author(s):

Ramesh Venkatesh ◽

Prachi Abhishek Dave ◽

Prachi Gurav ◽

Manisha Agarwal ◽

Mamta Jajoo ◽

...

Keyword(s):

Neonatal Intensive Care ◽

Cross Sectional Study ◽

Urban Setting ◽

North India ◽

Cross Sectional ◽

Systematic Screening ◽

Factors Affecting ◽

Preterm Babies ◽

The Mean

Abstract Background: To study and analyse the factors affecting the proportion of retinopathy of prematurity (ROP) distribution between the urban and semi-urban regions in North India. Methods: Retrospective, observational, cross-sectional study. All babies referred for ROP examination by paediatricians or other general ophthalmologists between 2013 – 2016 were included in the study. Demographic, clinical and treatment related findings were recorded. Results: Five hundred and fifty-eight (467: urban & 91: semi urban) babies were examined for ROP. The mean birth weight in the urban and semi-urban setting was 1348.6 ± 395.21 gm and 1703.77 ± 401.76 gm respectively. The mean gestational age was 30.99 ± 2.93 weeks and 30.73 ± 2.08 weeks in the urban and semi-urban cohorts respectively. The average time for first ophthalmic examination following birth was 23.82 ± 13.69 (range: 3-77) days in the urban and 101.16 ± 238.26 (range: 13- 330) days in the semi-urban setting. 94% of the babies completed all screening examination visits. Any ROP was identified in 11.6% and 33.0% of the urban and semi-urban cohorts respectively; Type 1 was detected in 7.5% of urban babies and 23.1% of semi-urban babies Conclusion: Differences in the proportion of babies developing any ROP and Type 1 ROP between the semi-urban and urban groups is likely due to selection bias, as a high proportion of semi-urban babies did not attend for examination or failed to complete all the examinations necessary. This was particularly true for females. More needs to be done to increase access to regular, systematic screening of preterm babies within neonatal units.

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A cross-sectional study on the correlation between postnatal foot length and various other anthropometric parameters along with the gestational age

Pediatric Review International Journal of Pediatric Research ◽

10.17511/ijpr.2020.i08.04 ◽

2020 ◽

Vol 7 (8) ◽

pp. 414-419

Author(s):

Dr. Abhinaya Arun Raj ◽

◽

Dr. K. Maheswari ◽

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Head Circumference ◽

Cross Sectional Study ◽

Chest Circumference ◽

Sectional Study ◽

Cross Sectional ◽

Foot Length ◽

The Mean ◽

R Value

Introduction: This study was done to assess the utility of foot length in determining theanthropometric parameters of a newborn in a tertiary care teaching hospital. Materials andMethods: This cross-sectional study among 270 newborns were done at Sri Venkateswaraa medicalcollege hospital and research centre, from Nov 2018 to May 2020. All the healthy live newbornswere taken into the study and newborns with congenital lower limb anomalies were excluded.Results: The mean birth weight of the neonate 2.948+0.344 kg which ranged from 2.050 kg to3.750kg. The mean foot length, head circumference and chest circumference of the foot length was8.113+0.468 cm, 48.989+1.093 cm, 34.437+0.659 cm and 32.372+0.734 cm respectively. The footlength had a maximum correlation with birth weight (r-value=0.905) followed by gestational age (r-value=0.809), length (r-value=0.786), head circumference (r-value=0.719) and chest circumference(r-value=0.603). Conclusion: Foot length had a significant correlation with birth weight andgestational age of the neonates. Foot length also correlated significantly with other anthropometricvariables like length, head circumference and chest circumference.

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Association of Birth Parameters with Refractive Status in a Sample of Caucasian Children Aged 4–17 Years

Journal of Ophthalmology ◽

10.1155/2015/635682 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Berna Akova-Budak ◽

Sertaç Argun Kıvanç ◽

Osman Okan Olcaysü

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Small For Gestational Age ◽

Age Groups ◽

Cross Sectional Study ◽

Cross Sectional ◽

Refractive Status ◽

Ophthalmologic Examination ◽

The Mean ◽

Age Range

Purpose. To investigate the association of birth parameters with refractive status in different age groups of Caucasian children.Materials and Methods. This cross-sectional study included 564 eyes of 282 children aged 4 to 17 years. All children underwent complete ophthalmologic examination. The children were divided into three groups according to their refractive status (emmetropia,myopia, and hyperopia), ages (4–7, 8-9, 10–12, and 13–17), and appropriateness for gestational age, respectively.Results. The mean age of the children was9.2±2.8(age range 4–17 years). The mean spheric equivalent was+0.3±1.7(range: (−10.0)–(+10.0) diopters). The mean birth weight and gestational age were2681.1±930.8grams (750–5000 grams) and37.2±3.7weeks (25–42 weeks). According to multinominal logistic regression analysis, children with myopia were more likely to have higher birth weights than emmetropic children (OR: 1.0, 95% CI: 1.000–1.001, andP=0.028). The hypermetropes were found to be significantly small for gestational age between 13 and 17 years of age.Conclusion. Birth weight and appropriateness for gestational age as birth parameters may have an impact on development of all types of refractive errors. The hypermetropic children tended to be small for gestational age.

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Prevalence and Risk Factors of Retinopathy of Prematurity (ROP): A Cross-Sectional Study

Ophthalmology Research An International Journal ◽

10.9734/or/2021/v15i330212 ◽

2021 ◽

pp. 1-6

Author(s):

Kishan A. Makvana ◽

Apurva H. Suthar

Keyword(s):

Risk Factors ◽

Birth Weight ◽

Gestational Age ◽

Retinopathy Of Prematurity ◽

Delayed Diagnosis ◽

Developed Countries ◽

Preterm Neonates ◽

Cross Sectional ◽

The Mean

Background and Aim: Despite considerable progress made in the treatment of Retinopathy of prematurity (ROP), it is still a common cause of reduced vision in children in developed countries, and its prevalence is increasing. This is a preventable disease and responds to treatments appropriately if diagnosed at early stages, but in case of delayed diagnosis and treatment, it may lead to blindness. The aim of the present study is to describe the incidence, severity, and risk factors of ROP in a tertiary healthcare center. Material and Methods: This was a prospective, observational, nonrandomized study conducted in a tertiary-level neonatal intensive care unit (NICU) of a teaching hospital in Gujarat. A total of 130 preterm neonates admitted in the NICU during the study period were screened for ROP as per the guidelines of NNF of India. Screening was done under topical anesthesia, and findings were documented according to the International Classification for Retinopathy of Prematurity recommendations. The data were analyzed for gestational age, birth weight, and systemic factors predisposing to ROP. Results: Of the 130 neonates, 37 neonates were found to have ROP, with the incidence of ROP being 28.4%. The mean birth weight (1388 ± 312 g) and the mean gestational age (32.21 ± 2.50 wk) Out of the 37 neonates with ROP, 14 had a gestational age of > 32 weeks and/or birth weight of > 1500 g. ROP was classified into type 1 and type 2 as per the ETROP study, 14 (39.39%) neonates had type 1 or treatable ROP; there were no cases of APROP in our study; ROP regressed without any intervention in 13 neonates; 7 neonates were defaulters; and 11 neonates were treated with laser. Conclusion: ROP is strongly associated with smaller, more immature, and sicker neonates. However, in our study, about 40% of neonates who developed ROP were of higher gestation (> 32 wk) and birth weight (> 1500 g). The analysis of risk factors for ROP development will help to understand and predict it in severe preterm infants.

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Hypoglycemia in preterm babies Incidence and risk factors

Paediatrica Indonesiana ◽

10.14238/pi41.2.2001.82-87 ◽

2001 ◽

Vol 41 (2) ◽

pp. 82

Author(s):

Asril Aminullah ◽

Dita Setiati ◽

Sudigdo Sastroasmoro

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Perinatal Asphyxia ◽

Univariate Analysis ◽

Cross Sectional Study ◽

Cross Sectional ◽

Preterm Babies ◽

The Mean ◽

Common Problems ◽

Meconium Staining

Hypoglycemia is one of the most common problems in neonates, especially in preterm babies. Although in themajority of cases the outcome is good, symptomatic or asymptomatic hypoglycemia may give significant complications thatmay cause death or developmental delay later in life. We conducted a cross sectional study from September 5, 1999 throughMay 8, 2000 to identify factors associated with hypoglycemia in preterm babies treated at the Division of Perinatology, CiptoMangunkusumo Hospital, Jakarta. There were 112 babies included in the study, with the mean gestational age of 33.3 (range22 to 37, SD 4.2) weeks, and mean birth weight of 1801 (range 850 to 2440, SD 420) grams. Twenty-seven of the 112 infantsshowed hypoglycemia. Univariate analysis disclosed that birth weight, degree of perinatal asphyxia, small for gestational age(SGA), presence of respiratory distress syndrome, mothers with preeclampsia or eclampsia, and mothers who had intravenousinfusion of glucose during labor were significantly associated with hypoglycemia in preterm babies. Gestational age,meconium staining, or infant of diabetic mother were not significantly associated with neonatal hypoglycemia. On logisticregression analysis to control confounders we found that only the degree of perinatal asphyxia and small for gestational agewere associated with hypoglycemia in those preterm babies.

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Quality of life of former preterm adolescents

Jornal Brasileiro de Psiquiatria ◽

10.1590/0047-2085000000200 ◽

2018 ◽

Vol 67 (3) ◽

pp. 159-165

Author(s):

Rozane Lapoli Sanz Casseb ◽

Ethel Cukierkorn Battikha ◽

Ana Lucia Goulart ◽

Anna Luiza Pires Vieira ◽

Marina Carvalho de Moraes Barros ◽

...

Keyword(s):

Quality Of Life ◽

Birth Weight ◽

Social Relationships ◽

Gestational Age ◽

Distress Syndrome ◽

Very Low Birth Weight ◽

Cross Sectional Study ◽

Cross Sectional ◽

The Mean

ABSTRACT Objectives: To compare the quality of life of adolescents born prematurely with very-low-birth-weight, reported by adolescents themselves and their caregivers, and analyze associated factors perceived by both. Methods: This cross-sectional study included former preterm adolescents born with gestational age < 37 weeks and birth weigh < 1,500 g, who were being followed up at the premature outpatient clinic of a university institution, from birth to adolescence, and their caregivers. Quality of life was assessed by the WHOQOL-BREF questionnaire. Factors associated with quality of life were analyzed by linear regression. Results: Of 91 eligible adolescents, 73 (80.2%) were included, being 38 (52.1%) male. The mean gestational age was 30.1 ± 2.4 weeks and birth weight was 1134 ± 239 g. Adolescents reported better quality of life than their caregivers (p = 0.011), being respectively: dissatisfied (1.4 vs. 4.1%), neither satisfied nor dissatisfied (20.5 vs. 20.5%), satisfied (56.2 vs. 71.2%) and very satisfied (21.9 vs. 4.1%). Scores attributed by adolescents and caregivers were, respectively: overall quality of life (4.0 ± 0.7 vs. 3.8 ± 0.6, p = 0.032), physical domain (3.6 ± 0.6 vs. 3.5 ± 0.6, p = 0.685), psychological domain (3.4 ± 0.6 vs. 3.6 ± 0.6, p = 0.116), social relationships (3.7 ± 0.7 vs. 3.6 ± 0.8, p = 0.371) and environment (3.4 ± 0.7 vs. 3.2 ± 0.6, p = 0.037). For caregivers, absence of fixed partner and hospitalization in childhood decreased the overall quality of life score; furthermore, the occurrence of respiratory distress syndrome increased this score. In the adolescents’ view, leukomalacia reduced this score. Conclusions: Adolescents reported better quality of life than caregivers. For adolescents, only biological factors were associated with quality of life scores; for caregivers, biological and social factors were associated this scores.

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Mid-arm circumference and mid-arm/head circumference ratio in term newborns

Sao Paulo Medical Journal ◽

10.1590/s1516-31802004000200004 ◽

2004 ◽

Vol 122 (2) ◽

pp. 53-59 ◽

Cited By ~ 4

Author(s):

Bettina Barbosa Duque Figueira ◽

Conceição Aparecida de Mattos Segre

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Head Circumference ◽

Cross Sectional Study ◽

Mean Value ◽

Cross Sectional ◽

Mean Values ◽

Arm Circumference ◽

Term Newborns ◽

The Mean

CONTEXT: Mid-arm circumference of the newborn is strongly associated with birth weight and is a very good indicator of low and insufficient birth weight. However, there are few Brazilian studies on the relationship between mid-arm and head circumferences and, thus, this does not form part of the routine evaluation for newborns. OBJECTIVES: To establish the mid-arm circumference and mid-arm/head circumference ratio in a population of term newborns. TYPE OF STUDY: Cross-sectional study carried out between June 1997 and August 1999. SETTING: Hospital Maternidade Leonor Mendes de Barros, São Paulo. PARTICIPANTS: Term newborns (66 males and 65 females) of appropriate growth for gestational age, whose mothers were healthy, were included in the study. MAIN MEASUREMENTS: Arm circumference, arm circumference/head circumference ratio, birth weight and gestational age were measured within 48 hours of birth. Data were considered significant when p < 0.01. RESULTS: The mean values for the mid-arm circumference were 10.76 cm (standard deviation, SD = 0.68) for females and 10.76 (SD = 0.81) for males. The mean value for the mid-arm/head circumference ratio was 0.31 (SD = 0.02) for both sexes. Mid-arm circumference values were significantly related to birth weight and gestational age, whereas mid-arm/head circumference ratio was related only to birth weight. CONCLUSIONS: Mid-arm circumference and mid-arm/head circumference ratio values were established for the studied population. It was possible to obtain curves for both mid-arm circumference and mid-arm/head circumference ratio in relation to birth weight. However, for mid-arm circumference, it was only possible to obtain curves in relation to gestational age. The use of the regression curves did not seem powerful enough to predict the mid-arm circumference and mid-arm/head circumference ratio in this population of term newborns. There were no gender differences for either of the measurements studied.

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