Postoperative Outcomes in Surgical COVID-19 Patients: A Multicenter Cohort Study

Abstract BackgroundData on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who undergone a surgery and the pandemic impact on surgical activities.MethodsWe conducted a multicenter cohort study between March 13 and June 19 2020. We included COVID-19 patients who underwent surgery in nine centres of the Province of Québec, the Canadian province most afflicted by the pandemic. We also included suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and overall surgical activities performed in participating centres. Our primary outcome was 30-day mortality. ResultsWe included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was 15.9%. This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22 616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44 486 cases).Conclusion In this study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was 15.9%. Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important. Trial registrationClinicalTrials.gov Identifier: NCT04458337

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Postoperative outcomes in surgical COVID-19 patients: a multicenter cohort study

BMC Anesthesiology ◽

10.1186/s12871-021-01233-9 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

François Martin Carrier ◽

Éva Amzallag ◽

Vincent Lecluyse ◽

Geneviève Côté ◽

Étienne J. Couture ◽

...

Keyword(s):

Cohort Study ◽

Primary Outcome ◽

Postoperative Mortality ◽

Pulmonary Complications ◽

Postoperative Outcomes ◽

Canadian Province ◽

Multicenter Cohort Study ◽

Time Of Surgery ◽

Multicenter Cohort ◽

Baseline Characteristics

Abstract Background Data on postoperative outcomes of the COVID-19 patient population is limited. We described COVID-19 patients who underwent a surgery and the pandemic impact on surgical activities. Methods We conducted a multicenter cohort study between March 13 and June 192,020. We included all COVID-19 patients who underwent surgery in nine centres of the Province of Québec, the Canadian province most afflicted by the pandemic. We also included concomitant suspected COVID-19 (subsequently confirmed not to have COVID-19) patients and patients who had recovered from it. We collected data on baseline characteristics, postoperative complications and postoperative mortality. Our primary outcome was 30-day mortality. We also collected data on overall surgical activities during this first wave and during the same period in 2019. Results We included 44 COVID-19 patients, 18 suspected patients, and 18 patients who had recovered from COVID-19 at time of surgery. Among the 44 COVID-19 patients, 31 surgeries (71%) were urgent and 16 (36%) were major. In these patients, pulmonary complications were frequent (25%) and 30-day mortality was high (15.9%). This mortality was higher in patients with symptoms (23.1%) compared to those without symptoms (5.6%), although not statistically significant (p = 0.118). Of the total 22,616 cases performed among participating centres during the study period, only 0.19% had COVID-19 at the time of surgery. Fewer procedures were performed during the study period compared to the same period in 2019 (44,486 cases). Conclusion In this Canadian cohort study, postoperative 30-day mortality in COVID-19 patients undergoing surgery was high (15.9%). Although few surgeries were performed on COVID-19 patients, the pandemic impact on surgical activity volume was important. Trial registration ClinicalTrials.gov Identifier: NCT04458337.

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Cardiorespiratory Comorbidity and Postoperative Complications following Esophagectomy: a European Multicenter Cohort Study

Annals of Surgical Oncology ◽

10.1245/s10434-019-07478-6 ◽

2019 ◽

Vol 26 (9) ◽

pp. 2864-2873 ◽

Cited By ~ 8

Author(s):

F. Klevebro ◽

J. A. Elliott ◽

A. Slaman ◽

B. D. Vermeulen ◽

S. Kamiya ◽

...

Keyword(s):

Cohort Study ◽

Postoperative Complications ◽

Multicenter Cohort Study ◽

Multicenter Cohort

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Geriatric Nutritional Risk Index, a predictive assessment tool, for postoperative complications after abdominal surgery: A prospective multicenter cohort study

Geriatrics and Gerontology International ◽

10.1111/ggi.13750 ◽

2019 ◽

Vol 19 (9) ◽

pp. 924-929 ◽

Cited By ~ 3

Author(s):

Masatoshi Hanada ◽

Kouta Yamauchi ◽

Shinjiro Miyazaki ◽

Jun Hirasawa ◽

Yohei Oyama ◽

...

Keyword(s):

Cohort Study ◽

Postoperative Complications ◽

Assessment Tool ◽

Risk Index ◽

Nutritional Risk ◽

Geriatric Nutritional Risk Index ◽

Multicenter Cohort Study ◽

Multicenter Cohort ◽

Nutritional Risk Index ◽

Predictive Assessment

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Short-Physical Performance Battery (SPPB) score is associated with postoperative pulmonary complications in elderly patients undergoing lung resection surgery: A prospective multicenter cohort study

Chronic Respiratory Disease ◽

10.1177/1479973120961846 ◽

2020 ◽

Vol 17 ◽

pp. 147997312096184

Author(s):

Masatoshi Hanada ◽

Kota Yamauchi ◽

Shinjiro Miyazaki ◽

Yohei Oyama ◽

Yorihide Yanagita ◽

...

Keyword(s):

Cohort Study ◽

Elderly Patients ◽

Physical Performance ◽

Lung Resection ◽

Pulmonary Complications ◽

Short Physical Performance Battery ◽

Postoperative Pulmonary Complications ◽

Multicenter Cohort Study ◽

Multicenter Cohort ◽

The Impact

Elderly patients awaiting lung resection surgery often have poor physical function, which puts them at a high risk of postoperative pulmonary complications. The aim of this study was to investigate the impact of preoperative physical performance on postoperative pulmonary complications in patients awaiting lung resection surgery. In this prospective multicenter cohort study, the characteristics of patients and postoperative pulmonary complications were compared between subjects with low (<10) and high (≥10) Short Physical Performance Battery (SPPB) scores. Postoperative pulmonary complications were defined as over grade II in Clavien-Dindo classification system. We estimated the effects of physical performance on postoperative pulmonary complications using multivariable hierarchical logistic regression. The postoperative pulmonary complications were compared between 331 patients in the high and 33 patients in the low SPPB group. Patients in the low SPPB score group had a significantly higher rate of postoperative pulmonary complications (p < 0.001). Low SPPB score was associated with a higher risk of postoperative pulmonary complications (odds ratio, 8.80; p < 0.001). The SPPB is a clinically useful evaluation tool to assess surgical patients’ physical performance. The low physical performance indicated by the SPPB may be predictive of postoperative pulmonary complications after lung resection surgery. Trial registration: Clinical Trials. University hospital Medical Information Network Center (UMIN-CTR) UMIN000021875.

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