scholarly journals Evaluation of Anterior Chamber Depth in 28,709 Adult Cataract Patients in China using Swept-Source Optical Biometry

2021 ◽  
Author(s):  
Qiong Lei ◽  
Haixia Tu ◽  
Xi Feng ◽  
Yong Wang
Keyword(s):  
Cataract Surgery ◽  
Anterior Chamber ◽  
Axial Length ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Regression Analysis ◽  
Swept Source ◽  
Mean Values ◽  
The Mean ◽  
Cataract Patients

Abstract Background: To create an anterior chamber depth (ACD) regression model for adult cataract surgery candidates from China, and to evaluate the distribution of their ocular biometric parameters.Methods: The ocular biometric records of 28,709 right eyes of cataract surgery candidates who were treated at Aier Eye Hospitals in nine cities from 2018 to 2019 were retrospectively analyzed. All measurements were taken with IOLMaster 700. We included patients who were at least 40 years old and were diagnosed with cataract.Results: The mean age of the patients was 68.6 ± 11.0 years. The mean values recorded were as follows: axial length (AL), 24.17 ± 2.47 mm; mean keratometry (Km) value, 44.09 ± 3.25 D; corneal astigmatism (CA), 1.06 ± 0.98 D; ACD, 3.02 ± 0.45 mm; lens thickness (LT), 4.52 ± 0.45 mm; central corneal thickness (CCT), 0.534 ± 0.04 mm; and white to white (WTW) corneal diameter, 11.64 ± 0.46 mm. The proportion of patients with long axial length (AL >25 mm) decreased with age. ACD, LT, AL, Km, WTW, and age were correlated. In the multivariate regression analysis of ACD, which included LT, AL, WTW, sex, Km, CCT, and age, there was a reasonable prediction with adjusted R2 = 0.629.Conclusions: The results show that high myopes are inclined to schedule cataract surgery at a younger age. LT and AL were found to be important factors that affect ACD. This study provides reference data for cataract patients from China.

scholarly journals Distribution of ocular biometric parameters and optimal model of anterior chamber depth regression in 28,709 adult cataract patients in China using swept‐source optical biometry

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiong Lei ◽  
Haixia Tu ◽  
Xi Feng ◽  
Julio Ortega-Usobiaga ◽  
Danmin Cao ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Anterior Chamber ◽  
Multivariate Regression ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Regression Analysis ◽  
Swept Source ◽  
Biometric Parameters ◽  
The Mean ◽  
Cataract Patients

Abstract Background The purpose of this study was to evaluate the ocular biometric parameters in adult cataract patients from China and create an anterior chamber depth (ACD) regression model. Methods The ocular biometric records of 28,709 right eyes of cataract surgery candidates who were treated at Aier Eye Hospitals in nine cities from 2018 to 2019 were retrospectively analyzed. All measurements were taken with IOLMaster 700. We included patients who were at least 40 years old and were diagnosed with cataract. Results The mean age of the patients was 68.6 ± 11.0 years. The mean values recorded were as follows: axial length (AL), 24.17 ± 2.47 mm; mean keratometry (Km) value, 44.26 ± 1.70 D; corneal astigmatism (CA), 1.06 ± 0.96 D; ACD, 3.02 ± 0.45 mm; lens thickness (LT), 4.52 ± 0.45 mm; central corneal thickness (CCT), 0.534 ± 0.04 mm; and white to white (WTW) corneal diameter, 11.64 ± 0.46 mm. ACD correlated positively with AL (Spearman coefficient, 0.544) and WTW (0.300), but negatively with LT (-0.660) and age (-0.285) (all P < 0.01). In the multivariate regression analysis of ACD, which included LT, AL, WTW, sex, Km, CCT, and age, there was a reasonable prediction with adjusted R2 = 0.641. Conclusions Cataract patients with longer AL and wider WTW have deeper ACD. With increasing age and lens thickening ACD becomes shallower. Based on the standardized coefficients of ACD multivariate regression analysis from the study, LT is the main factor that affects ACD, and is followed by AL.

scholarly journals Ocular Biometry and Corneal Astigmatism in Patients Undergoing Cataract Surgery in Bheri Zone of Nepal

2017 ◽  
Vol 15 (2) ◽  
pp. 53-57
Author(s):  
Bikram Bahadur Thapa ◽  
Y. Dhakal ◽  
J. K. Verma ◽  
P. Manandhar
Keyword(s):  
Cataract Surgery ◽  
Anterior Chamber ◽  
Axial Length ◽  
Anterior Chamber Depth ◽  
College Teaching ◽  
Visual Outcome ◽  
Corneal Astigmatism ◽  
Medical College ◽  
The Mean ◽  
Cataract Patients

 Introduction: Accurate measurement of ocular axial length, keratometry and anterior chamber depth before cataract surgery is crucial for calculating the power of intraocular lens (IOL) to be implanted. Corneal astigmatism is one of the major thefts to have best postoperative unaided visual acuity. Thus, knowing it preoperatively and taking appropriate intervention during surgery provides best postoperative visual outcome. But there are no studies on corneal astigmatism and biometric parameters in the population of Bheri Zone. MATERIAL AND METHOD: The medical records of the patients who had  ndergone cataract surgery between January 2017 and November 2017 at Nepalgunj medical college were retrospectively reviewed and analyzed. Patient's demographic parameter, keratometric value, anterior chamber depth, lens thickness and axial length data were collected and analyzed. RESULTS: This study evaluated the data in 65 eyes of 65 patients who had undergone cataract surgery. The mean age of patients was 59.3 ± 15.71 years. The mean corneal astigmatism was 1.37 D ±1.4D (range 0.00-6.75D). Corneal astigmatism was higher than 1.00 D in 32.3% of cases. The mean average keratometry was 44.54±1.83D. The magnitude of corneal astigmatism was positively correlated with age (p<0. 001) and there was a tendency for corneal astigmatism to increase with age above 50 years. Against-the-rule regular astigmatism was the most common type (46.2%) of astigmatism observed in this study. CONCLUSION: The present report showed the pattern of corneal astigmatism before cataract surgery in the patients at Nepalgunj Medical College Teaching Hospital. One third of cataract patients had corneal astigmatism of more than 1.0D. This finding provide the important normative reference and help ophthalmologists to plan and manage the cost-effective correction of preexisting corneal astigmatism in cataract patients to achieve the best visual outcome.

scholarly journals Analysis of Lens Thickness Distribution Based on Swept-Source Optical Coherence Tomography (SS-OCT)

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xi Feng ◽  
Yong Wang ◽  
Jianheng Liang ◽  
Yali Xu ◽  
Julio Ortega-Usobiaga ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Negative Correlation ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Biometric Data ◽  
Swept Source ◽  
Age Related ◽  
Cataract Patients

Objective. This study aimed to analyze the distribution of lens thickness (LT) and its associations in age-related cataract patients based on swept-source optical coherence tomography (SS-OCT). Methods. This cross-sectional study included 59,726 Chinese age-related cataract patients. Only right-eye data were included in the study. Repeated measures of ocular parameters were performed using an IOL Master 700 device. The distributions of ocular biometric data including anterior chamber depth (ACD), LT, axial length (AL), central corneal thickness (CCT), white-to-white (WTW), and mean keratometry (MK) and their associations with age were assessed. The anterior segment (AS) was measured as the sum of CCT, ACD, and LT, while the vitreous chamber depth (VCD) was calculated as the difference between AL and AS. The values of LT : AL, AS : AL, and VCD : AL in different AL groups and their changes are the main outcome measures used to observe the proportion of the anterior and posterior segments of the eye. Results. Biometric data were available for 59,726 individuals. The mean age was 68.81 years (range = 40–100); 40.62% were male and 59.38% were female. Mean anterior chamber depth (ACD) was 3.02 ± 0.44 mm, mean LT was 4.51 ± 0.44 mm, mean axial length (AL) was 23.89 ± 1.92 mm, mean central corneal thickness (CCT) was 0.53 ± 0.03 mm, mean white-to-white (WTW) was 11.64 ± 0.44 mm, and mean keratometry (MK) was 44.27 ± 1.65 diopter. Female patients had shorter AL, shallower ACD, smaller CCT and WTW, decreased LT, and steeper corneas ( p  < 0.005). ACD revealed the strongest negative correlation ( p  ≤ 0.001, r = –0.682) with LT. Age ( p  ≤ 0.001, r = 0.348) showed a moderate positive correlation, whereas MK ( p  ＜ 0.05, r = 0.011), CCT ( p  ≤ 0.001, r = 0.041) had a weak positive correlation and WTW ( p  ≤ 0.001, r = –0.034) had a weak negative correlation with LT. A nonlinear correlation was found between LT and AL. LT increased with age in both males and females. LT changed variably in eyes with AL less than 27 mm, LT decreased as AL increased, then LT gradually increased as AL increased in extremely long and extra-long eyes ( p  ≤ 0.001). LT : AL and AS : AL decreased as AL increased, VCD : AL gradually increased as AL increased in highly myopic eyes, and VCD : AL increased by about 0.01 for every 1 mm increase in AL. Conclusions. Among Chinese age-related cataract patients, we found LT to have the strongest relation with ACD. The lens was thicker in elderly patients and women. The correlation between LT and AL is not a simple negative correlation; with the increase of age, LT decreases first and then increases. The proportion of VCD is constantly rising with the elongation of AL.

Comparison of Axial Length and Anterior Chamber Depth Measurement among Optical, Applanation and Immersion Biometry

2019 ◽  
Vol 11 (1) ◽  
pp. 59-64
Author(s):  
Harun Ur Rashid ◽  
AQM Omar Sharif ◽  
Zinat Rehana Shipu ◽  
Debashish Ghosh ◽  
Sofia Akhter ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Anterior Chamber ◽  
Axial Length ◽  
Anterior Chamber Depth ◽  
Power Calculation ◽  
Strong Positive Correlation ◽  
Care Hospital ◽  
Optical Biometry ◽  
Depth Measurement ◽  
The Mean

Background: Precise biometry is one of the major key factors for obtaining desired refractive outcome after cataract surgery. Visual outcome strongly depends on accuracy of ocular parameters especially axial length (AL) and anterior chamber depth (ACD). It is very important to evaluate different biometry methods to have accurate measurements for IOL power calculation. Objective: The aim of the study is to compare and analyze the difference between the measurement of axial length (AL) and anterior chamber depth (ACD) using ultrasound applanation, immersion and optical biometry. Methodology: A prospective study conducted on 168 patients enrolled for cataract surgery from January 2018 to December 2018 in Dhaka Eye Care Hospital, Dhaka. 280 eyes have been tested by a single observer. Axial length (AL) and anterior chamber depth (ACD) was measured consecutively by optical, applanation and immersion biometry. The results have been statistically evaluated to establish efficacy and correlation among the three methods of biometry. Results: Statistical analysis showed the mean of axial length (AL) obtained from optical biometry is 23.36 ± 1.99 mm, which is 0.10mm (p=0.00) less by applanation biometry and 0.04 mm (p=0.00) less by immersion biometry. For anterior chamber depth (ACD), the mean value from optical biometry is 3.13 ± 0.47mm. This value is highest in compare to both applanation (0.002 mm less with p = 0.824) and immersion (0.04 mm less with p = 0.00) biometry. Further analysis reveals strong correlation of optical biometry with applanation biometry (r = 0.994 for AL and 0.945 for ACD) and immersion biometry (r = 0.995 for AL and 0.947 for ACD). Conclusion: The study reveals that among optical, applanation and immersion method the optical biometry method appeared to be the most precise way of measuring axial length (AL) and anterior chamber depth (ACD) of eye. The study also shows an excellent agreement and strong positive correlation of optical biometry with applanation and immersion biometry. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 59-64

Evaluation of biometric parameters in phacomorphic glaucoma and mature cataracts

2020 ◽  
pp. 112067212091453
Author(s):  
Ali Keleş ◽  
Emine Şen ◽  
Ufuk Elgin
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Odds Ratio ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Mature Cataract ◽  
Biometric Parameters ◽  
Significant Difference ◽  
The Mean

Purpose: The aims of this study were to compare the biometric parameters and axial lengths of eyes with phacomorphic glaucoma and mature cataract and to identify differences that might predispose to development of phacomorphic glaucoma. Methods: Three hundred forty-two patients were enrolled in this retrospective study. The eyes were divided into four groups—Group (G)1: phacomorphic glaucoma ( n = 29), G2: mature cataract ( n = 313), G3: contralateral phacomorphic glaucoma ( n = 29), and G4: contralateral mature cataract ( n = 313). Central corneal thickness and anterior chamber depth were assessed by optical low-coherence reflectometry (Lenstar LS 900®; Haag-Streit AG, Switzerland), while axial length was determined by A-scan ultrasound biometry. Results: The mean central corneal thickness of G1 was significantly higher than in other groups ( p < 0.001) and the mean anterior chamber depth of G1 was the lowest among the groups ( p < 0.001). Also, G2 had lower mean anterior chamber depth than G4 ( p < 0.001) and G3 had lower mean anterior chamber depth than G4 ( p = 0.007). Anterior chamber depth less than 3.27 mm had the higher odds ratio for distinguishing G3 versus G4 (odds ratio = 10.79, p < 0.001). Furthermore, patients aged ⩾68.9 years had the higher odds ratio for distinguishing G1 versus G2 (odds ratio = 2.82, p = 0.019). There was no significant difference in the presence of pseudoexfoliation material between G1 and G2 ( p = 0.057). There were no significant differences in axial length values among the four groups ( p = 0.097). Conclusion: Advanced age and shallow anterior chamber depth were found to be risk factors for developing phacomorphic glaucoma, but the presence of pseudoexfoliation material was not found to play a role as a risk factor in phacomorphic glaucoma development.

Inter-Observer Reproducibility of Axial Ocular Measurements with Non-contact HAAG-STRAIT Biometer

2021 ◽  
Vol 37 (3) ◽  
Author(s):  
Muhammad Suhail Sarwar ◽  
Sehrish Shahid ◽  
Muhammad Arslan Ashraf ◽  
Shaista Kanwal
Keyword(s):  
Data Analysis ◽  
Anterior Chamber ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Excellent Correlation ◽  
Interclass Correlation ◽  
The Mean

Purpose:  To check inter observer reproducibility of axial ocular measurements i.e. central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth (AD), lens thickness (LT), anterior segment lens (ASL), vitreous length (VL) and axial length (AL) with non-contact HAAG-STRAIT biometer. Study Design:  Comparative Reproducibility Analysis. Place and Duration of Study:  College of ophthalmology and allied vision sciences (COAVS), Mayo Hospital, Lahore. Methods:  This study included 66 healthy students (132 eyes). Data was collected through self-designed proforma by 2 operators independently. SPSS 21 was used for data analysis. Interclass correlation was applied for agreement between the two readings. Interclass coefficient (ICC) value greater than 0.7 was considered as excellent correlation. Results:  The mean CCT, AD, ACD, LT, ASL, VL, and AL were 526.47 ± 35.72 µm and 526.47 ± 36.06 µm (ICC = 0.92); 2.93 ± 0.29 mm and 2.93 ± 0.29 mm (ICC = 0.81); 3.45 ± 0.30 mm and 3.46 ± 0.30 mm (ICC = 0.79); 3.58 ± 0.28 mm and 3.56 ± 0.22 mm (ICC = 0.76); 7.03 ± 0.30 mm and 7.02 ± 0.27 mm (ICC = 0.80); 16.56 ± 0.85 mm and 16.62 ± 0.81 mm (ICC = 0.72); and 23.59 ± 0.85 mm and 23.64 ± 0.87 mm (ICC: 0.76) of observer 1 and 2, respectively. Conclusion:  Non-contact Biometer (HAAG-STRAIT) has high inter-observer reproducibility with strong interclass coefficient of greater than 0.72. Key Words:  Biometry, Axial Length, Central Corneal Thickness, Anterior Chamber Depth.

scholarly journals Comparison between a New Optical Biometry Device and an Anterior Segment Optical Coherence Tomographer for Measuring Central Corneal Thickness and Anterior Chamber Depth

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Jinhai Huang ◽  
Weicong Lu ◽  
Giacomo Savini ◽  
Hao Chen ◽  
Chengfang Wang ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Normal Subjects ◽  
Optical Coherence ◽  
Limits Of Agreement ◽  
Mean Values ◽  
The Mean

Purpose.To compare between a new optical biometer (AL-Scan, Nidek Co., Aichi, Japan) and an anterior segment optical coherence tomographer (Visante AS-OCT, Carl Zeiss Meditec, Dublin, USA) for measuring central corneal thickness (CCT), anterior chamber depth (ACD), and aqueous depth (AD).Methods.Sixty-three eyes of 63 normal subjects were examined with AL-Scan and Visante AS-OCT in this prospective study. One eye per subject was measured three times with both devices to record their CCT, ACD, and AD. All procedures were performed by the same operator. Agreement between the two devices was assessed using pairedt-tests, Bland-Altman plots, and 95% limits of agreement (LoA).Results.The mean CCT, ACD, and AD measured by AL-Scan were538.59±27.37 μm,3.70±0.30 mm, and3.16±0.30 mm, respectively. The mean values obtained by the Visante OCT were536.14±26.61 μm for CCT,3.71±0.29 mm for ACD, and3.17±0.29 mm for AD. The mean CCT by the AL-Scan was higher than that obtained by the Visante AS-OCT (difference =2.45±6.07 μm,P<0.05). The differences in ACD and AD measurements were not statistically significant. The 95% LoA of CCT, ACD, and AD were between −9.44 and 14.35 μm, −0.15 and 0.12 mm, and −0.15 and 0.12 mm, respectively.Conclusions.Since these two devices were comparable for measuring CCT, ACD, and AD, their results can be interchangeably used in the clinic.

scholarly journals Presbyopia and its anatomical and physiological variants

1970 ◽  
Vol 3 (2) ◽  
pp. 155-158
Author(s):  
M Gupta ◽  
RR Sukul ◽  
Y Gupta ◽  
M Dey ◽  
A Phougat ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Physiological Parameters ◽  
Corneal Curvature ◽  
Lens Thickness ◽  
Significant Difference ◽  
The Mean

Aim: To study the various ocular anatomical and physiological parameters in presbyopia. Materials and methods: We studied the various ocular anatomical and physiological parameters like corneal curvature (keratometry readings: K1 and K2), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and axial length (AL) in 100 presbyopic patients between 35 - 55 years of age. The patients were divided into two age groups: I (35 – 44 years) and II (45-55 yrs). ACD, AL and LT were measured using an Ascan. CCT was measured with ultrasonic pachymetry. Results: The CCT decreased (BE), LT increased and ACD decreased (RE) significantly with increasing age (p < 0.05). There was no significant difference in males and females. Nearly 3/4th of the total increase in lens thickness was responsible for the decrease in the anterior chamber depth and the rest, 1/4th , goes posteriorly. Corneal curvature and AL showed no significant change with age. Conclusions: The mean of CCT decreased significantly with advancing age. As age increased, the mean value of lens thickness increased and anterior chamber depth decreased. Nearly 3/ 4th of total increase in LT was anteriorly, decreasing the ACD. Corneal curvature and AL has no relation with age. Key words: Presbyopia, central corneal thickness, anterior chamber depth, lens thickness, axial length DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5269 Nepal J Ophthalmol 2011; 3(2): 155-158

scholarly journals Refractive error and biometrics of anterior segment of eyes of healthy young university students in Japan

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kumiko Kato ◽  
Mineo Kondo ◽  
Maki Takeuchi ◽  
Koji Hirano
Keyword(s):  
University Students ◽  
Anterior Chamber ◽  
Refractive Error ◽  
Axial Length ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Japanese University ◽  
The Mean ◽  
Corneal Diameter

Abstract To determine the parameters of the anterior segment of eyes that are significantly associated with the refractive error in healthy young Japanese university students. This was a cross-sectional observational study of 229 healthy Japanese university students (men: women,147:82) whose age ranged between 20 to 29 years. Univariate and multivariate linear regression analyses were performed to identify the factors that were significantly correlated with the refractive error. The independent variables included age, sex, axial length, anterior chamber depth, corneal diameter, curvature of anterior surface of cornea, and central corneal thickness. The mean refractive error (spherical equivalent) was −4.1 ± 2.7 diopters (D) with a range of −12.5 to +0.5 D, and the mean axial length was 25.4 ± 1.3 mm with a range of 22.4 to 29.0 mm. Pearson univariate correlation analysis found that the refractive error was significantly and negatively correlated with the axial length (R = −0.82, P < 0.001), deeper anterior chamber (R = −0.30, P < 0.001), and larger corneal diameter (R = −0.21, P = 0.001). Multiple regression analysis showed that the refractive error was significantly associated with a longer axial length (P < 0.001), a deeper anterior chamber (P < 0.001), and a flatter corneal curvature (P < 0.001).The biometric values of the anterior segment of the eyes should make the eye more hyperopic which would reduce the myopia-inducing lengthening of the axial length.

scholarly journals Changes in anterior segment optical coherence tomography following pars plana vitrectomy without tamponade

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alireza Khodabande ◽  
Massood Mohammadi ◽  
Hamid Riazi-Esfahani ◽  
Shahab Karami ◽  
Massood Mirghorbani ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Pars Plana Vitrectomy ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Optical Coherence ◽  
Mean Values ◽  
Iop Measurement ◽  
Pars Plana ◽  
The Mean

Abstract Background To evaluate changes in anterior segment morphology on anterior segment optical coherence tomography (AS-OCT) following pars plana vitrectomy (PPV) without tamponade. Methods Patients who underwent PPV without tamponade for epiretinal membrane were evaluated. Eligible patients underwent intraocular pressure (IOP) measurement and AS-OCT preoperatively as well as 1 month and 6 months post-operatively. Anterior chamber width (ACW), anterior chamber depth (ACD), trabecular iris angle (TIA), angle opening distance at 500 and 750 µm (AOD), and trabecular iris space area at 500 and 750 µm (TISA) at four quadrants were recorded and analyzed. Additionally, the mean values of TIA (MTIA), AOD (MAOD), and TISA (MTISA) for each eye (mean of four quadrants) were analyzed. Results 23 patients completed the study. The mean age of participants was 56.4 ± 3.6 years of age and 13/23 (56%) were female. Mean IOP of patients was 18.1 ± 1.1, 18.3 ± 1.1, and 18.1 ± 1.2 preoperatively,1 month post-operatively, and 6 months post-operatively, respectively. (p = 0.83). No difference was detected post-operatively in measurements of ACW, ACD, MTIA, MAOD500, MAOD750, MTISA500, and MTISA750. Conclusion Pars plana vitrectomy without tamponade was not associated with changes in anterior chamber morphology.

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