Effect of physical exercise in bariatric surgery patients: protocol of a randomized controlled clinical trial.

Abstract Background: Bariatric surgery is an effective approach to weight loss and long-term comorbidity resolution. Although recommended in several guidelines, supervised exercise has not been systematically prescribed after bariatric surgery. The aim of this study is to determine the effects of two types of exercise, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT), on body composition, cardiopulmonary function and perceived quality of life in bariatric surgery patients.Methods: This randomized controlled exploratory pilot trial will include 75 adults of both sexes scheduled for bariatric surgery. They will be randomly assigned to one of three groups: 1) MICT, 2) HIIT, or 3) a control group. The intervention will occur 2 days a week for 4 months. Outcomes will be assessed at four points: 1) one week before surgery; 2) 21 days after surgery (baseline before the exercise program); 3) 8 weeks after beginning the exercise program; and 4) one week after the end of intervention. Primary outcomes will include body composition, heart rate variability, and six-minute walk test and quality of life scores. Secondary outcomes will be maximal respiratory pressure, flowmeter, hand dynamometry, and 30-second sit-to-stand test results.Discussion: Both exercise protocols in this study were developed according to evidence-based practice. It is expected that, after 16 weeks of intervention, body composition (measured by electrical bioimpedance), cardiopulmonary function (measured by heart rate variability, maximal inspiratory pressure, maximal expiratory pressure, peak expiratory flow, handgrip strength, and the six-minute walk test) and perceived quality of life (measured by the Moorehead-Ardelt quality of life questionnaire II and bariatric analysis and reporting outcome system scores) will improve, especially in the HIIT group.Trial registration: ClinicalTrials.gov, NCT04235842, registered 22 January 2020.

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Effect of Physical Exercise in Bariatric Surgery Patients: Protocol of a Randomized Controlled Clinical Trial

10.21203/rs.3.rs-21324/v1 ◽

2020 ◽

Author(s):

Andrea Herrera ◽

Andrea Tabach ◽

Karen Andaur ◽

Antonio Zamunér

Keyword(s):

Quality Of Life ◽

Bariatric Surgery ◽

Body Composition ◽

Exercise Program ◽

Controlled Clinical Trial ◽

Randomized Controlled ◽

Six Minute Walk Test ◽

Perceived Quality Of Life ◽

Minute Walk

Abstract Background: Bariatric surgery is an effective approach to weight loss and long-term comorbidity resolution. Although recommended in several guidelines, supervised exercise has not been systematically prescribed after bariatric surgery. The aim of this study is to determine the effects of two types of exercise, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT), on body composition, cardiopulmonary function and perceived quality of life in bariatric surgery patients.Methods: This randomized controlled clinical trial will include 75 adults of both sexes scheduled for bariatric surgery. They will be randomly assigned to one of three groups: 1) MICT, 2) HIIT, or 3) a control group. The intervention will occur 2 days a week for 4 months. Outcomes will be assessed at four points: 1) one week before surgery; 2) 21 days after surgery (baseline before the exercise program); 3) 8 weeks after beginning the exercise program; and 4) one week after the end of intervention. Primary outcomes will include body composition, heart rate variability, and six-minute walk test and quality of life scores. Secondary outcomes will be maximal respiratory pressure, flowmeter, hand dynamometry, and 30-second sit-to-stand test results.Discussion: Both exercise protocols in this study were developed according to evidence-based practice. It is expected that, after 16 weeks of intervention, body composition (measured by electrical bioimpedance), cardiopulmonary function (measured by heart rate variability, maximal inspiratory pressure, maximal expiratory pressure, peak expiratory flow, handgrip strength, and the six-minute walk test) and perceived quality of life (measured by the Moorehead-Ardelt quality of life questionnaire II and bariatric analysis and reporting outcome system scores) will improve, especially in the HIIT group.Trial registration: ClinicalTrials.gov, NCT04235842, registered 22 January 2020.

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Effect of physical exercise in bariatric surgery patients: protocol of a randomized controlled clinical trial

Trials ◽

10.1186/s13063-021-05056-4 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Andrea Herrera-Santelices ◽

Andrea Tabach-Apraiz ◽

Karen Andaur-Cáceres ◽

Antonio Roberto Zamunér

Keyword(s):

Quality Of Life ◽

Bariatric Surgery ◽

Heart Rate ◽

Heart Rate Variability ◽

Body Composition ◽

Exercise Program ◽

Walk Test ◽

Randomized Controlled ◽

Perceived Quality Of Life

Abstract Background Bariatric surgery is an effective approach to weight loss and long-term comorbidity resolution. Although recommended in several guidelines, supervised exercise has not been systematically prescribed after bariatric surgery. The aim of this study is to determine the effects of two types of exercise, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT), on body composition, cardiopulmonary function, and perceived quality of life in bariatric surgery patients. Methods This randomized controlled exploratory pilot trial will include 75 adults of both sexes scheduled for bariatric surgery. They will be randomly assigned to one of three groups: (1) MICT, (2) HIIT, or (3) a control group. The intervention will occur 2 days a week for 4 months. Outcomes will be assessed at four points: (1) 1 week before surgery, (2) 21 days after surgery (baseline before the exercise program), (3) 8 weeks after beginning the exercise program, and (4) 1 week after the end of intervention. Primary outcomes will include body composition, heart rate variability, and 6-min walk test and quality of life scores. Secondary outcomes will be maximal respiratory pressure, flowmeter, hand dynamometry, and 30-s sit-to-stand test results. Discussion Both exercise protocols in this study were developed according to evidence-based practice. It is expected that, after 16 weeks of intervention, body composition (measured by electrical bioimpedance), cardiopulmonary function (measured by heart rate variability, maximal inspiratory pressure, maximal expiratory pressure, peak expiratory flow, handgrip strength, and the 6-min walk test), and perceived quality of life (measured by the Moorehead-Ardelt quality of life questionnaire II and bariatric analysis and reporting outcome system scores) will improve, especially in the HIIT group. Trial registration ClinicalTrials.gov NCT04235842. Registered on 22 January 2020.

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Efficacy and Safety of an mHealth App and Wearable Device in Physical Performance for Patients With Hepatocellular Carcinoma: Development and Usability Study

JMIR mhealth and uhealth ◽

10.2196/14435 ◽

2020 ◽

Vol 8 (3) ◽

pp. e14435 ◽

Cited By ~ 3

Author(s):

Yoon Kim ◽

Jinserk Seo ◽

So-Yeon An ◽

Dong Hyun Sinn ◽

Ji Hye Hwang

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Body Composition ◽

Physical Fitness ◽

Exercise Program ◽

Walk Test ◽

6 Minute Walk Test ◽

Minute Walk ◽

Rehabilitation Exercise

Background Exercise is predicted to have a positive effect among hepatocellular carcinoma (HCC) patients. However, these patients are hesitant to start and build up an exercise program for one major reason: the vague fear of developing hepatic decompensation, a potentially fatal condition that can lead to death. Integrating mobile health (mHealth) with individualized exercise programs could be a possible option for promoting physical capacity among HCC patients. Objective The aim of this study was to evaluate the efficacy and safety of rehabilitation exercises, which have been individually prescribed via an mHealth app, on physical fitness, body composition, biochemical profile, and quality of life among HCC patients. Methods A total of 37 HCC patients were enrolled in a 12-week course with an mHealth app program targeted to HCC patients. The wearable wristband device Neofit (Partron Co) was provided to participants, and recorded daily physical data, such as the number of steps, calorie expenditure, exercise time, and heart rate. Each participant was given an individualized rehabilitation exercise program that was prescribed and adjusted at the 6-week midintervention period based on the assessment results. At baseline, 6-week, and 12-week sessions, participants’ physical fitness levels (ie, 6-minute walk test, grip strength test, and 30-second chair stand test) were measured. Physical activity levels, as measured by the International Physical Activity Questionnaire-Short Form (IPAQ-SF); body composition (ie, body mass index, body fat percentage, and muscle mass); biochemical profiles; and quality of life, as measured by the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30, were assessed at baseline and at the end point. At the 6-week midpoint, exercise intensity was individually adjusted. Results Of the 37 patients, 31 (84%) completed the 12-week intervention. Grip strength improved significantly after 12 weeks of the intervention. The 30-second chair stand test and the 6-minute walk test showed significant improvement from 0 to 6 weeks, from 0 to 12 weeks, and from 6 to 12 weeks. Muscle mass and the IPAQ-SF score increased significantly after 12 weeks of the intervention without biochemical deterioration. Conclusions Following 12 weeks of mHealth care, including an individually prescribed rehabilitation exercise program, we saw significant improvements in physical fitness, body composition, and physical activity without any complication or biochemical deterioration among compensated HCC patients who had completed therapy.

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Efficacy and Safety of an mHealth App and Wearable Device in Physical Performance for Patients With Hepatocellular Carcinoma: Development and Usability Study (Preprint)

10.2196/preprints.14435 ◽

2019 ◽

Author(s):

Yoon Kim ◽

Jinserk Seo ◽

So-Yeon An ◽

Dong Hyun Sinn ◽

Ji Hye Hwang

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Body Composition ◽

Physical Fitness ◽

Exercise Program ◽

Walk Test ◽

6 Minute Walk Test ◽

Minute Walk ◽

Rehabilitation Exercise

BACKGROUND Exercise is predicted to have a positive effect among hepatocellular carcinoma (HCC) patients. However, these patients are hesitant to start and build up an exercise program for one major reason: the vague fear of developing hepatic decompensation, a potentially fatal condition that can lead to death. Integrating mobile health (mHealth) with individualized exercise programs could be a possible option for promoting physical capacity among HCC patients. OBJECTIVE The aim of this study was to evaluate the efficacy and safety of rehabilitation exercises, which have been individually prescribed via an mHealth app, on physical fitness, body composition, biochemical profile, and quality of life among HCC patients. METHODS A total of 37 HCC patients were enrolled in a 12-week course with an mHealth app program targeted to HCC patients. The wearable wristband device Neofit (Partron Co) was provided to participants, and recorded daily physical data, such as the number of steps, calorie expenditure, exercise time, and heart rate. Each participant was given an individualized rehabilitation exercise program that was prescribed and adjusted at the 6-week midintervention period based on the assessment results. At baseline, 6-week, and 12-week sessions, participants’ physical fitness levels (ie, 6-minute walk test, grip strength test, and 30-second chair stand test) were measured. Physical activity levels, as measured by the International Physical Activity Questionnaire-Short Form (IPAQ-SF); body composition (ie, body mass index, body fat percentage, and muscle mass); biochemical profiles; and quality of life, as measured by the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30, were assessed at baseline and at the end point. At the 6-week midpoint, exercise intensity was individually adjusted. RESULTS Of the 37 patients, 31 (84%) completed the 12-week intervention. Grip strength improved significantly after 12 weeks of the intervention. The 30-second chair stand test and the 6-minute walk test showed significant improvement from 0 to 6 weeks, from 0 to 12 weeks, and from 6 to 12 weeks. Muscle mass and the IPAQ-SF score increased significantly after 12 weeks of the intervention without biochemical deterioration. CONCLUSIONS Following 12 weeks of mHealth care, including an individually prescribed rehabilitation exercise program, we saw significant improvements in physical fitness, body composition, and physical activity without any complication or biochemical deterioration among compensated HCC patients who had completed therapy.

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Abstract 17469: Comparing the Effect of CRT Implantation on Quality of Life in Older Patients Compared With Younger Patients: Systematic Review and Meta-Analysis

Circulation ◽

10.1161/circ.142.suppl_3.17469 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Praveen Ponnamreddy ◽

Saeed Juggan ◽

Lauren Gilstrap

Keyword(s):

Quality Of Life ◽

Older Patients ◽

Meta Analysis ◽

Nyha Class ◽

Age Group ◽

Walk Test ◽

Younger Patients ◽

Six Minute Walk Test ◽

Minute Walk

Background: CRT had been accepted as standard of care for patients with HFrEF who qualify for the therapy. The pivotal CRT trials enrolled patients significantly younger than the typical HFrEF patients seen in the community. Benefits of CRT in older HFrEF patients is largely unknown. We sought to evaluate the change in quality of life in older patients undergoing CRT in comparison to younger patients. Hypothesis: CRT implantation is associated with comparable improvements in quality of life in younger patients (age <70) and older patients (age 70 and above). Methods: PubMed, The Cochrane Library, Scopus, and Web of Science were queried for comparative effectiveness studies of CRT in older HFrEF patients. We gathered data for Quality of life measurements including improvement in NYHA class, MLHFQ, Six minute walk test. MLHFQ, Six minute walk test data was analyzed qualitatively as data was insufficient to impute Standard deviation for mean change. Changes in NYHA class was analyzed quantitatively. Random effects meta-analysis of improvement in NYHA class and relative risk (RR) is reported along with estimates of heterogeneity Results: Seven studies [n=2494 for younger group and n=1035 for older group] were included in changes in NYHA class meta-analysis. Older age group patients had similar improvement in NYHA class compared to younger age group patients. Relative risk 0.99 with 95%CI 0.93-1.06 (figure). Five studies reported Baseline and follow up MLHFQ scores for both the groups. All the five studies reported improvements in MLHFQ in both the groups. Three studies reported change in six minute walk test in meters before and after CRT implantation. All the studies reported improvement in six minute walk test both in younger and older group. Conclusions: People older than 70 years of age with heart failure with reduced ejection fraction who qualify for CRT derive similar benefits with improvement in quality of life compared to patients aged less than 70 years of age.

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