scholarly journals Pre- and Postoperative Parameters on Magnetic Resonance Imaging Predict Continence Recovery after Laparoscopic Radical prostatectomy

2020 ◽  
Author(s):  
Fan Zhang ◽  
Bin Yang ◽  
Ye Yan ◽  
Yichang Hao ◽  
Yi Huang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Radical Prostatectomy ◽  
Proportional Hazards ◽  
Removal Rate ◽  
Cox Proportional Hazards ◽  
Laparoscopic Radical Prostatectomy ◽  
Rank Test ◽  
Resonance Imaging ◽  
Vesicourethral Anastomosis

Abstract Background: To evaluate the association between pre- and postoperative parameters on magnetic resonance imaging (MRI) and continence recovery after laparoscopic radical prostatectomy (LRP). Methods: 73 patients who underwent LRP were retrospectively reviewed. Demographic characteristics, clinicopathologic outcomes and several MRI parameters before and after surgery were evaluated. Continence was defined as no pad per day. Early continence recovery was defined as continence recovery within 3 months. Kaplan-Meier analyses and log-rank test were used to compare time to continence recovery. Cox proportional-hazards regression analyses were performed to identify independent predictors of continence recovery after LRP.Results: Patients with smaller prostatic volume, shorter intravesical prostatic protrusion length (IPPL), longer preoperative membranous urethral length (MUL), lower MUL-removal rate, triangular vesicourethral anastomosis (VUA) and neurovascular bundle sparing experienced a faster continence recovery (All, p < 0.05). Multivariate analyses revealed IPPL (hazard ratio [HR]: 0.94, p = 0.044), preoperative MUL (HR: 1.10, p = 0.032), MUL-removal rate (HR: 0.91, p = 0.007) and shape of VUA (square vs. triangle, HR: 2.30, p = 0.012) were independent predictors of continence recovery after LRP.Conclusion: IPPL, preoperative MUL, MUL-removal rate and shape of VUA were promising parameters on MRI for predicting continence recovery after LRP.

scholarly journals Pre- and Postoperative Parameters on Magnetic Resonance Imaging Predict Continence Recovery after Laparoscopic Radical prostatectomy

2020 ◽  
Author(s):  
Fan Zhang ◽  
Bin Yang ◽  
Ye Yan ◽  
Yichang Hao ◽  
Yi Huang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Radical Prostatectomy ◽  
Scoring System ◽  
Removal Rate ◽  
Laparoscopic Radical Prostatectomy ◽  
Resonance Imaging ◽  
Vesicourethral Anastomosis ◽  
Risk Scoring ◽  
Risk Scoring System

Abstract Background: To evaluate the association between pre- and postoperative parameters on magnetic resonance imaging (MRI) and continence recovery after laparoscopic radical prostatectomy (LRP). To develop a risk scoring system for predicting continence recovery after LRP. Methods: 73 patients who underwent LRP were retrospectively reviewed. Demographic characteristics, clinicopathologic outcomes and several MRI parameters before and after surgery were evaluated. Continence was defined as no pad per day. Early continence recovery was defined as continence recovery within 3 months. Kaplan-Meier analyses and log-rank test were used to compare time to continence recovery. Cox proportional-hazards regression analyses were performed to identify independent predictors of continence recovery. Results: Patients with smaller prostatic volume, shorter intravesical prostatic protrusion length (IPPL), shorter preoperative membranous urethral length (MUL), lower MUL-removal rate, triangular vesicourethral anastomosis (VUA) and neurovascular bundle sparing experienced a faster continence recovery (All, p < 0.05). Multivariate analyses revealed IPPL (hazard ratio [HR]: 0.94, p = 0.044), preoperative MUL (HR: 1.10, p = 0.032), MUL-removal rate (HR: 0.91, p = 0.007) and shape of VUA (square vs. triangle, HR: 2.30, p = 0.012) were independent predictors of continence recovery. The four parameters were therefore used to develop a risk scoring system, termed Post-Prostatectomy Incontinence Score (PPIS) and ranging from 0 to 4. We observed early continence recovery in 100%, 84.6%, 27.8%, 0% and 0% of patients with a PPIS of 0, 1, 2, 3, 4, respectively. Conclusion: IPPL, preoperative MUL, MUL-removal rate and shape of VUA were independently predictors of continence recovery. PPIS could accurately predict the early continence recovery after LRP.

scholarly journals Prognostic Value of Classifying Parapharyngeal Extension in Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging

2015 ◽  
Vol 2015 ◽  
pp. 1-8
Author(s):  
Guo-Yi Zhang ◽  
Ying Huang ◽  
Xue-Feng Hu ◽  
Xiang-Ping Chen ◽  
Tao Xu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Nasopharyngeal Carcinoma ◽  
Prognostic Value ◽  
Cox Proportional Hazards ◽  
Rank Test ◽  
Retropharyngeal Space ◽  
Resonance Imaging ◽  
Free Survival ◽  
Masticator Space

Purpose. To subclassify parapharyngeal extension in nasopharyngeal carcinoma (NPC) and investigate its prognostic value and staging categories based on magnetic resonance imaging (MRI).Methods and Materials. Data from 1504 consecutive NPC patients treated with definitive-intent radiotherapy were analyzed retrospectively. Sites of parapharyngeal extension were defined by MRI. Overall survival (OS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) were calculated by the Kaplan-Meier method and compared with the log-rank test. Hazard consistency and hazard discrimination were determined by multivariate analysis with Cox proportional hazards models.Results. 1104 patients (73.4%) had parapharyngeal extension; 1.7–63.8% had involvement of various anatomic sites. The hazard ratio for death was significantly higher with extensive parapharyngeal extension (lateral pterygoid muscle of masticator space and beyond or parotid space) than with mild extension (medial pterygoid muscle of masticator space, or carotid, prestyloid, and prevertebral or retropharyngeal space). OS, LRFS, and DMFS with extensive parapharyngeal extension were similar to those in T4 disease; OS, LRFS, and DMFS with mild parapharyngeal extension were significantly higher than in those T3 disease (allP≤ 0.015).Conclusions. Parapharyngeal extension in NPC should be subclassified as mild or extensive, which should be regarded as stages T2 and T4 diseases, respectively.

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